HitPredict

Protein: SIR2
NAD-dependent protein deacetylase sirtuin-2 (EC 2.3.1.286) (NAD-dependent protein defatty-acylase sirtuin-2) (EC 2.3.1.-) (Regulatory protein SIR2 homolog 2) (SIR2-like protein 2)

Gene: SIR2, Sirt2
Organism: Rattus norvegicus
Interactions: 2
UniProt ID: Q5RJQ4

Gene Ontology (top 5):
GO:0000122 - negative regulation of transcription by RNA polymerase II
GO:0000792 - heterochromatin
GO:0003682 - chromatin binding
GO:0003950 - NAD+ ADP-ribosyltransferase activity
GO:0004407 - histone deacetylase activity