Protein: MED7
Mediator of RNA polymerase II transcription subunit 7 (Mediator complex subunit 7)

Gene: MED7
Organism: Candida albicans SC5314
Interactions: 89
UniProt ID: Q5AEN6

Gene Ontology (top 5):
GO:0000122 - negative regulation of transcription by RNA polymerase II
GO:0003713 - transcription coactivator activity
GO:0006357 - regulation of transcription by RNA polymerase II
GO:0016592 - mediator complex
GO:0032968 - positive regulation of transcription elongation by RNA polymerase II

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

1202728

MED8
Mediator of RNA polymerase II transcription subunit 8

2

2

Small-scale

0.754

High

1202739

MED4
Mediator of RNA polymerase II transcription subunit 4

1

2

Small-scale

0.618

High

1202814

MED10
Mediator of RNA polymerase II transcription subunit 10

1

6

Small-scale

0.618

High

1202860

MED21
Mediator of RNA polymerase II transcription subunit 21

1

1

Small-scale

0.618

High

1202871

MED7
Mediator of RNA polymerase II transcription subunit 7

1

1

Small-scale

0.618

High

1202872

MED14
Mediator of RNA polymerase II transcription subunit 14

1

3

Small-scale

0.618

High

1202877

MED17
Mediator of RNA polymerase II transcription subunit 17

1

2

Small-scale

0.618

High

1202700

MED16
Mediator of RNA polymerase II transcription subunit 16

1

1

Small-scale

0.479

High

1202762

MED18
Mediator of RNA polymerase II transcription subunit 18

1

1

Small-scale

0.479

High

1202717

MED11
Mediator of RNA polymerase II transcription subunit 11

1

0

Small-scale

0.458

High

1202848

MED22
Mediator of RNA polymerase II transcription subunit 22

1

0

Small-scale

0.458

High

1202876

Q5AHH0
Mediator of RNA polymerase II transcription subunit 1

1

0

Small-scale

0.458

High

313517

MPG1
Mannose-1-phosphate guanyltransferase

1

1

Small-scale

0.437

High

835804

HSP71
Heat shock protein HSP70

1

3

Small-scale

0.437

High

857676

HSP72
Heat shock protein SSA2

1

3

Small-scale

0.437

High

857758

HSP90
Heat shock protein 90 homolog

1

2

Small-scale

0.437

High

1013920

GBLP
Small ribosomal subunit protein RACK1

1

1

Small-scale

0.437

High

1018100

IF4A
ATP-dependent RNA helicase eIF4A

1

2

Small-scale

0.437

High

1202745

ERB1
Ribosome biogenesis protein ERB1

1

1

Small-scale

0.437

High

1202755

Q59WB7
Ribosome assembly protein 1

1

2

Small-scale

0.437

High

1202776

Q59YE8
Eukaryotic peptide chain release factor GTP-binding subunit

1

1

Small-scale

0.437

High

1202777

Q59YH4
T-complex protein 1 subunit eta

1

1

Small-scale

0.437

High

1202791

EF2
Elongation factor 2

1

2

Small-scale

0.437

High

1202813

Q5A397
Hsp70 chaperone Ssb

1

3

Small-scale

0.437

High

1202846

Q5A8Y5
DNA-directed RNA polymerase subunit beta

1

2

Small-scale

0.437

High

1202854

Q5AB84
RRM domain-containing protein

1

1

Small-scale

0.437

High

1202856

Q5ABC3
Elongation factor Tu

1

1

Small-scale

0.437

High

1202875

Q5AGZ8
ATP-dependent 6-phosphofructokinase

1

1

Small-scale

0.437

High

1202880

DBP5
ATP-dependent RNA helicase DBP5

1

1

Small-scale

0.437

High

1202883

Q5AK53
ATP-dependent 6-phosphofructokinase

1

1

Small-scale

0.437

High

1202887

Q5ANP6
Sbp1p

1

1

Small-scale

0.437

High

1202888

YTM1
Ribosome biogenesis protein YTM1

1

1

Small-scale

0.437

High

148841

CATA
Peroxisomal catalase

1

0

Small-scale

0.249

Low

206084

1433
14-3-3 protein homolog

1

0

Small-scale

0.249

Low

206085

RSSA
Small ribosomal subunit protein uS2

1

0

Small-scale

0.249

Low

237879

RL13
Large ribosomal subunit protein eL13

1

0

Small-scale

0.249

Low

515427

EF1A1
Elongation factor 1-alpha 1

1

0

Small-scale

0.249

Low

643210

PPIA
Peptidyl-prolyl cis-trans isomerase

1

0

Small-scale

0.249

Low

828609

RS3A
Small ribosomal subunit protein eS1

1

0

Small-scale

0.249

Low

845386

PHR1
pH-responsive protein 1

1

0

Small-scale

0.249

Low

857879

KPYK
Pyruvate kinase

1

0

Small-scale

0.249

Low

922807

GFA1
Glutamine--fructose-6-phosphate aminotransferase [isomerizing]

1

0

Small-scale

0.249

Low

1011042

PMGY
Phosphoglycerate mutase

1

0

Small-scale

0.249

Low

1013922

IPYR
Inorganic pyrophosphatase

1

0

Small-scale

0.249

Low

1013925

PDC1
Pyruvate decarboxylase

1

0

Small-scale

0.249

Low

1013926

G6PI
Glucose-6-phosphate isomerase

1

0

Small-scale

0.249

Low

1202630

Q59MZ5
Phosphoribosylformylglycinamidine synthase

1

0

Small-scale

0.249

Low

1202695

SUN41
Secreted beta-glucosidase SUN41

1

0

Small-scale

0.249

Low

1202698

EIF3A
Eukaryotic translation initiation factor 3 subunit A

1

0

Small-scale

0.249

Low

1202703

VATB
V-type proton ATPase subunit B

1

0

Small-scale

0.249

Low

1202709

Q59R20
proline--tRNA ligase

1

0

Small-scale

0.249

Low

1202734

Q59TD5
NADH dehydrogenase [ubiquinone] flavoprotein 1, mitochondrial

1

0

Small-scale

0.249

Low

1202742

Q59US5
Homocysteine/cysteine synthase

1

0

Small-scale

0.249

Low

1202760

Q59WG3
AAA family ATPase

1

0

Small-scale

0.249

Low

1202761

PESC
Pescadillo homolog

1

0

Small-scale

0.249

Low

1202774

MP65
Cell surface mannoprotein MP65

1

0

Small-scale

0.249

Low

1202784

Q59ZH8
Translation termination factor eRF1

1

0

Small-scale

0.249

Low

1202792

Q5A0N3
Ribonucleoside-diphosphate reductase

1

0

Small-scale

0.249

Low

1202806

Q5A1E8
Succinate dehydrogenase [ubiquinone] flavoprotein subunit, mitochondrial

1

0

Small-scale

0.249

Low

1202810

NSA2
Ribosome biogenesis protein NSA2

1

0

Small-scale

0.249

Low

1202811

Q5A330
Pex19p

1

0

Small-scale

0.249

Low

1202815

Q5A3K7
2-oxoglutarate reductase

1

0

Small-scale

0.249

Low

1202816

Q5A3N5
Large ribosomal subunit protein mL50

1

0

Small-scale

0.249

Low

1202819

DED1
ATP-dependent RNA helicase DED1

1

0

Small-scale

0.249

Low

1202821

Q5A4W7
Fatty acid synthase subunit beta

1

0

Small-scale

0.249

Low

1202822

Q5A516
ADP/ATP translocase

1

0

Small-scale

0.249

Low

1202831

Q5A6M6
Coatomer subunit beta

1

0

Small-scale

0.249

Low

1202832

Q5A6Q6
Small ribosomal subunit protein uS4m

1

0

Small-scale

0.249

Low

1202833

RL15A
Large ribosomal subunit protein eL15

1

0

Small-scale

0.249

Low

1202837

Q5A750
Transketolase

1

0

Small-scale

0.249

Low

1202844

TCTP
Translationally-controlled tumor protein homolog

1

0

Small-scale

0.249

Low

1202853

Q5AAU7
Eukaryotic translation initiation factor 2 subunit alpha

1

0

Small-scale

0.249

Low

1202859

EIF3J
Eukaryotic translation initiation factor 3 subunit J

1

0

Small-scale

0.249

Low

1202862

Q5ADM7
Glyceraldehyde-3-phosphate dehydrogenase

1

0

Small-scale

0.249

Low

1202867

Q5AEB8
Proteasome subunit alpha type

1

0

Small-scale

0.249

Low

1202868

CAF17
Iron-sulfur cluster assembly factor IBA57 homolog, mitochondrial

1

0

Small-scale

0.249

Low

1202870

RL9B
Large ribosomal subunit protein uL6

1

0

Small-scale

0.249

Low

1202873

RS5
Small ribosomal subunit protein uS7

1

0

Small-scale

0.249

Low

1202874

Q5AGX8
Acetyltransferase component of pyruvate dehydrogenase complex

1

0

Small-scale

0.249

Low

1202878

PABP
Polyadenylate-binding protein, cytoplasmic and nuclear

1

0

Small-scale

0.249

Low

1202879

RS7A
Small ribosomal subunit protein eS7

1

0

Small-scale

0.249

Low

1202881

RL12
Large ribosomal subunit protein uL11

1

0

Small-scale

0.249

Low

1202882

Q5AK00
RRM domain-containing protein

1

0

Small-scale

0.249

Low

1202884

Q5AKW2
Myosin 2

1

0

Small-scale

0.249

Low

1202885

ARO1
Pentafunctional AROM polypeptide [Includes: 3-dehydroquinate synthase

1

0

Small-scale

0.249

Low

1202886

DEF1
RNA polymerase II degradation factor 1

1

0

Small-scale

0.249

Low

1202889

PUR6
Phosphoribosylaminoimidazole carboxylase

1

0

Small-scale

0.249

Low

1202890

KAPR
cAMP-dependent protein kinase regulatory subunit

1

0

Small-scale

0.249

Low


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Last updated: 11Aug2025