Protein: CTNB1
Catenin beta-1 (Beta-catenin)

Gene: CTNB1, Ctnnb1
Organism: Rattus norvegicus
Interactions: 136
UniProt ID: Q9WU82

Gene Ontology (top 5):
GO:0000122 - negative regulation of transcription by RNA polymerase II
GO:0000165 - MAPK cascade
GO:0000209 - protein polyubiquitination
GO:0000578 - embryonic axis specification
GO:0000791 - euchromatin

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

1000466

APC
Adenomatous polyposis coli protein

3

20

Small-scale

0.817

High

312201

MAGI2
Membrane-associated guanylate kinase, WW and PDZ domain-containing protein 2

2

20

Small-scale

0.628

High

93016

D3ZRM5
Ras-related protein Rab-23

1

6

High-throughput

0.618

High

98854

F1M2G3
Ras-related and estrogen-regulated growth inhibitor

1

4

High-throughput

0.618

High

147917

NUP50
Nuclear pore complex protein Nup50

1

20

High-throughput

0.618

High

1490147

CADH2
Cadherin-2

1

20

Small-scale

0.618

High

73334

B1WC54
G1/S-specific cyclin-E1

1

6

Small-scale

0.561

High

1231092

CCNA1
Cyclin-A1

1

5

Small-scale

0.561

High

1220366

ITM2B
Integral membrane protein 2B

1

1

High-throughput

0.536

High

930656

AAPK1
5'-AMP-activated protein kinase catalytic subunit alpha-1

1

0

High-throughput

0.513

High

1243145

Q6P751
Cyclin-dependent kinase 2

1

10

Small-scale

0.501

High

1189

A0A096MKF8
Mediator complex subunit 12

1

16

High-throughput

0.479

High

50144

RFOX2
RNA binding protein fox-1 homolog 2

1

5

High-throughput

0.479

High

50958

APC5
Anaphase-promoting complex subunit 5

1

1

High-throughput

0.479

High

60449

A2RRT6
Zinc finger CCCH-type antiviral protein 1

1

3

High-throughput

0.479

High

73545

B2GUZ3
Monofunctional C1-tetrahydrofolate synthase, mitochondrial

1

2

High-throughput

0.479

High

73555

B2GV01
Metastasis-associated gene family, member 2

1

13

High-throughput

0.479

High

76711

B4F7B3
Dynein axonemal intermediate chain 3

1

10

High-throughput

0.479

High

81567

B5DEQ4
Small nuclear ribonucleoprotein polypeptide B2

1

6

High-throughput

0.479

High

92810

D3Z8H0
U1 small nuclear ribonucleoprotein 70 kDa

1

10

High-throughput

0.479

High

92812

D3Z8L5
Pumilio homolog 1

1

1

High-throughput

0.479

High

92836

D3ZAX5
Calcium homeostasis endoplasmic reticulum protein

1

2

High-throughput

0.479

High

92877

D3ZCX1
Methyl-CpG binding domain protein 6

1

11

High-throughput

0.479

High

92980

D3ZM64
Protein Jade-1

1

6

High-throughput

0.479

High

93007

D3ZQM0
Splicing factor 3A subunit 1

1

4

High-throughput

0.479

High

93009

D3ZQN7
Laminin subunit beta-1

1

7

High-throughput

0.479

High

93018

D3ZRN2
Mediator of RNA polymerase II transcription subunit 1

1

6

High-throughput

0.479

High

93035

D3ZSK6
Dishevelled-binding antagonist of beta-catenin 2

1

2

Small-scale

0.479

High

93037

D3ZSL5
Tyrosine-protein phosphatase non-receptor type

1

20

High-throughput

0.479

High

93072

D3ZUV9
CCR4-NOT transcription complex subunit 3

1

8

High-throughput

0.479

High

93105

D3ZV15
E3 ubiquitin-protein ligase CBL

1

5

Small-scale

0.479

High

93146

D3ZXH7
Aly/REF export factor

1

5

High-throughput

0.479

High

93159

D3ZZ81
PTPRF interacting protein alpha 1

1

5

Small-scale

0.479

High

93175

D3ZZZ0
AT hook containing transcription factor 1

1

11

High-throughput

0.479

High

93202

D4A1Z8
Ras-associating and dilute domain-containing protein

1

18

High-throughput

0.479

High

93229

D4A3S8
tRNA

1

2

High-throughput

0.479

High

93269

D4A7B5
NK2 homeobox 8

1

3

High-throughput

0.479

High

93277

D4A7U1
Zyxin

1

7

High-throughput

0.479

High

93285

D4A8H8
Cytoplasmic FMR1-interacting protein

1

3

High-throughput

0.479

High

93296

D4A9P0
Kinesin family member 7

1

4

High-throughput

0.479

High

93357

D4AEI5
Myelin expression factor 2

1

3

High-throughput

0.479

High

97313

E9PTR4
Ubiquitin associated protein 2-like

1

8

High-throughput

0.479

High

98559

F1LM55
Cell cycle and apoptosis regulator 2

1

3

High-throughput

0.479

High

98630

F1LSK5
HEAT repeat containing 5A

1

1

High-throughput

0.479

High

98889

F1M8G6
DNA polymerase zeta catalytic subunit

1

2

High-throughput

0.479

High

98890

F1M8I6
non-specific serine/threonine protein kinase

1

16

High-throughput

0.479

High

98916

F1MAG8
Semaphorin 3D

1

1

High-throughput

0.479

High

108139

SRSF6
Serine/arginine-rich splicing factor 6

1

3

High-throughput

0.479

High

415089

TPM1
Tropomyosin alpha-1 chain

1

4

High-throughput

0.479

High

415164

CATA
Catalase

1

2

High-throughput

0.479

High

465299

CXA1
Gap junction alpha-1 protein

1

7

Small-scale

0.479

High

482993

TPM4
Tropomyosin alpha-4 chain

1

5

High-throughput

0.479

High

505905

M3K7
Mitogen-activated protein kinase kinase kinase 7

1

5

High-throughput

0.479

High

581805

SYDC
Aspartate--tRNA ligase, cytoplasmic

1

2

High-throughput

0.479

High

613671

GSK3B
Glycogen synthase kinase-3 beta

1

12

Small-scale

0.479

High

613889

PSA3
Proteasome subunit alpha type-3

1

3

High-throughput

0.479

High

639538

PSA4
Proteasome subunit alpha type-4

1

3

High-throughput

0.479

High

649466

FBRL
rRNA 2'-O-methyltransferase fibrillarin

1

1

High-throughput

0.479

High

701102

PSB6
Proteasome subunit beta type-6

1

5

High-throughput

0.479

High

701257

PSB5
Proteasome subunit beta type-5

1

3

High-throughput

0.479

High

712712

SERPH
Serpin H1

1

1

High-throughput

0.479

High

771529

NMDZ1
Glutamate receptor ionotropic, NMDA 1

1

4

Small-scale

0.479

High

954939

PSA6
Proteasome subunit alpha type-6

1

2

High-throughput

0.479

High

976960

EF1A1
Elongation factor 1-alpha 1

1

1

High-throughput

0.479

High

977648

PP2AB
Serine/threonine-protein phosphatase 2A catalytic subunit beta isoform

1

6

High-throughput

0.479

High

989526

IF4E
Eukaryotic translation initiation factor 4E

1

1

High-throughput

0.479

High

995941

ACTC
Actin, alpha cardiac muscle 1

1

6

High-throughput

0.479

High

1017568

ACTZ
Alpha-centractin

1

8

High-throughput

0.479

High

1017571

EFTU
Elongation factor Tu, mitochondrial

1

3

High-throughput

0.479

High

1022044

GRIP1
Glutamate receptor-interacting protein 1

1

16

Small-scale

0.479

High

1028058

NMDE1
Glutamate receptor ionotropic, NMDA 2A

1

4

Small-scale

0.479

High

1028069

NMDE2
Glutamate receptor ionotropic, NMDA 2B

1

4

Small-scale

0.479

High

1041952

BUP1
Beta-ureidopropionase

1

1

High-throughput

0.479

High

1083825

K2C8
Keratin, type II cytoskeletal 8

1

1

High-throughput

0.479

High

1181565

AIMP2
Aminoacyl tRNA synthase complex-interacting multifunctional protein 2

1

1

High-throughput

0.479

High

1186462

ATD3A
ATPase family AAA domain-containing protein 3A

1

9

High-throughput

0.479

High

1193306

Q498M8
Tip-associated protein

1

3

High-throughput

0.479

High

1195184

RING2
E3 ubiquitin-protein ligase RING2

1

20

High-throughput

0.479

High

1216902

Q5U302
Catenin alpha-1

1

12

High-throughput

0.479

High

1220196

LARP7
La-related protein 7

1

12

High-throughput

0.479

High

1220209

FXR1
RNA-binding protein FXR1

1

6

High-throughput

0.479

High

1224385

K1C19
Keratin, type I cytoskeletal 19

1

2

High-throughput

0.479

High

1224556

UBC
Polyubiquitin-C [Cleaved into: Ubiquitin; Ubiquitin-related]

1

7

Small-scale

0.479

High

1224607

HYOU1
Hypoxia up-regulated protein 1

1

8

High-throughput

0.479

High

1225805

RTN1
Reticulon-1

1

1

High-throughput

0.479

High

1225810

PTPRF
Receptor-type tyrosine-protein phosphatase F

1

19

Small-scale

0.479

High

1226353

Q66H79
E3 ubiquitin-protein ligase TRIM32

1

10

High-throughput

0.479

High

1229390

Q68HB5
Protocadherin 7, isoform CRA_b

1

1

High-throughput

0.479

High

1235368

Q6JBI7
LMO7a

1

7

High-throughput

0.479

High

1243143

DAB2P
Disabled homolog 2-interacting protein

1

6

High-throughput

0.479

High

1247835

Q6TUD1
Asparagine--tRNA ligase, cytoplasmic

1

2

High-throughput

0.479

High

1282859

FMR1
Fragile X messenger ribonucleoprotein 1

1

6

High-throughput

0.479

High

1317375

SCMC2
Mitochondrial adenyl nucleotide antiporter SLC25A25

1

3

High-throughput

0.479

High

1317380

CASC3
Protein CASC3

1

5

High-throughput

0.479

High

1341632

FAT3
Protocadherin Fat 3

1

4

High-throughput

0.479

High

1354095

HNRH1
Heterogeneous nuclear ribonucleoprotein H

1

5

High-throughput

0.479

High

1408952

PLCE1
1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase epsilon-1

1

1

High-throughput

0.479

High

1424436

MAGD1
Melanoma-associated antigen D1

1

3

High-throughput

0.479

High

1440943

PRP19
Pre-mRNA-processing factor 19

1

17

High-throughput

0.479

High

1490148

SC31A
Protein transport protein Sec31A

1

17

High-throughput

0.479

High

81565

B5DEM7
Transcription elongation factor SPT4

1

0

High-throughput

0.458

High

81570

B5DF15
Interleukin 17 receptor B

1

0

High-throughput

0.458

High

92968

D3ZKK5
phosphatidylinositol-3,5-bisphosphate 3-phosphatase

1

0

High-throughput

0.458

High

93038

D3ZSQ1
Pecanex-like protein

1

0

High-throughput

0.458

High

93039

D3ZSU7
Migration and invasion enhancer 1

1

0

High-throughput

0.458

High

93124

D3ZVN7
Amine oxidase

1

0

High-throughput

0.458

High

93181

D4A065
ADAM metallopeptidase with thrombospondin type 1 motif, 6

1

0

High-throughput

0.458

High

98612

F1LR02
Collagen type XVIII alpha 1 chain

1

0

High-throughput

0.458

High

548661

KCC2G
Calcium/calmodulin-dependent protein kinase type II subunit gamma

1

0

High-throughput

0.458

High

613734

CSDE1
Cold shock domain-containing protein E1

1

0

High-throughput

0.458

High

772431

IDE
Insulin-degrading enzyme

1

0

High-throughput

0.458

High

1194072

Q4G079
Aminoacyl tRNA synthetase complex-interacting multifunctional protein 1

1

0

High-throughput

0.458

High

1208524

Q5PQX2
Cytochrome P450 3A

1

0

High-throughput

0.458

High

1216892

SPS2L
SPATS2-like protein

1

0

High-throughput

0.458

High

1220429

Q5XIR5
BAG family molecular chaperone regulator 4

1

0

High-throughput

0.458

High

1225712

SC65
Endoplasmic reticulum protein SC65

1

0

High-throughput

0.458

High

1231094

STN1
CST complex subunit STN1

1

0

High-throughput

0.458

High

1250437

MYADM
Myeloid-associated differentiation marker

1

0

High-throughput

0.458

High

1455814

DCTN4
Dynactin subunit 4

1

0

High-throughput

0.458

High

93131

D3ZWB4
Spermatogenesis associated 13

1

2

Small-scale

0.445

High

580589

INSR
Insulin receptor

1

20

High-throughput

0.445

High

621319

GLUT4
Solute carrier family 2, facilitated glucose transporter member 4

1

3

High-throughput

0.445

High

98861

F1M392
LIM and calponin homology domains 1

1

6

High-throughput

0.437

High

104790

F7F9U6
Plectin

1

4

High-throughput

0.437

High

867915

PGS1
Biglycan

1

1

High-throughput

0.437

High

1203412

Q5BK91
Proto-oncogene vav

1

6

High-throughput

0.437

High

1209075

Q5RKG9
Eukaryotic translation initiation factor 4B

1

3

High-throughput

0.437

High

1220210

Q5XI84
EGF-containing fibulin-like extracellular matrix protein 2

1

3

High-throughput

0.437

High

92811

D3Z8H9
Coiled-coil domain containing 103

1

0

High-throughput

0.249

Low

92921

D3ZG43
NADH dehydrogenase [ubiquinone] iron-sulfur protein 3, mitochondrial

1

0

High-throughput

0.249

Low

93195

D4A175
tRNA dimethylallyltransferase

1

0

High-throughput

0.249

Low

93245

D4A4H5
Stromal cell derived factor 2

1

0

High-throughput

0.249

Low

93319

D4AC70
Collagen type VIII alpha 1 chain

1

0

High-throughput

0.249

Low

551676

COX5B
Cytochrome c oxidase subunit 5B, mitochondrial

1

0

High-throughput

0.249

Low

1274397

GCP60
Golgi resident protein GCP60

1

0

High-throughput

0.249

Low

1274398

Q7TP77
Large ribosomal subunit protein mL49

1

0

High-throughput

0.249

Low


Service provided by Combinatics, Japan

Last updated: 11Aug2025