HitPredict - High confidence protein-protein interactions

Protein: HMGCL
Hydroxymethylglutaryl-CoA lyase, mitochondrial (HL) (HMG-CoA lyase) (EC 4.1.3.4) (3-hydroxy-3-methylglutarate-CoA lyase)

Gene: HMGCL
Organism: Mus musculus
Interactions: 7
UniProt ID: P38060

Gene Ontology (top 5):
GO:0000287 - magnesium ion binding
GO:0004419 - hydroxymethylglutaryl-CoA lyase activity
GO:0005198 - structural molecule activity
GO:0005739 - mitochondrion
GO:0005743 - mitochondrial inner membrane

Download interactions: TXT MITAB-2.5

Interaction	Interactor	Experiments	Homologs	Category	Interaction Score	Confidence
107208	F8VQL0 Hepatocyte growth factor receptor	1	1	High-throughput	0.437	High
398142	CFAD Complement factor D	1	2	High-throughput	0.437	High
46496	SIM43 Small integral membrane protein 43	1	0	High-throughput	0.249	Low
660925	IRF8 Interferon regulatory factor 8	1	0	High-throughput	0.249	Low
792504	FACD2 Fanconi anemia group D2 protein homolog	1	0	High-throughput	0.249	Low
792505	FNDC5 Fibronectin type III domain-containing protein 5	1	0	High-throughput	0.249	Low
792503	PP1A Serine/threonine-protein phosphatase PP1-alpha catalytic subunit	1	0	High-throughput	0.232	Low

Service provided by Combinatics, Japan

Last updated: 11Aug2025