Protein: SINA
E3 ubiquitin-protein ligase sina (EC 2.3.2.27) (RING-type E3 ubiquitin transferase sina) (Seven in absentia protein)

Gene: SINA
Organism: Drosophila melanogaster
Interactions: 138
UniProt ID: P21461

Gene Ontology (top 5):
GO:0000151 - ubiquitin ligase complex
GO:0004842 - ubiquitin-protein transferase activity
GO:0005634 - nucleus
GO:0005737 - cytoplasm
GO:0005829 - cytosol

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

598805

SINA
E3 ubiquitin-protein ligase sina

3

16

Small-scale

0.871

High

598831

PHYL
Protein phyllopod

10

1

Small-scale

0.759

High

598815

TTKA
Protein tramtrack, alpha isoform

5

13

Small-scale

0.720

High

598874

Q9VFT4
AT27578p

3

4

High-throughput

0.653

High

598893

Q9VRY7
GH13213p

3

1

High-throughput

0.646

High

598853

EBI
F-box-like/WD repeat-containing protein ebi

2

6

Small-scale

0.639

High

598909

Q9W3H5
GEO04367p1

4

1

High-throughput

0.628

High

598858

Q9V3G9
AT18705p

3

1

High-throughput

0.596

High

53272

A1Z8K2
FI20150p1

2

1

High-throughput

0.596

High

248375

O62602
mitogen-activated protein kinase kinase

2

12

High-throughput

0.594

High

396157

HUNB
Protein hunchback

2

3

High-throughput

0.594

High

598807

DSX
Protein doublesex

2

1

High-throughput

0.594

High

598808

POXM
Paired box pox-meso protein

2

1

High-throughput

0.594

High

598809

POXN
Paired box pox-neuro protein

2

1

High-throughput

0.594

High

598812

UBE2N
Ubiquitin-conjugating enzyme E2 N

2

20

High-throughput

0.594

High

598814

ERKA
Mitogen-activated protein kinase ERK-A

2

8

High-throughput

0.594

High

598818

UBCD4
Ubiquitin-conjugating enzyme E2-22 kDa

2

20

High-throughput

0.594

High

598819

UBC84
Ubiquitin-conjugating enzyme E2-18 kDa

2

20

High-throughput

0.594

High

598823

ESMC
Enhancer of split mgamma protein

2

1

High-throughput

0.594

High

598824

RSMB
Small nuclear ribonucleoprotein-associated protein B

2

2

High-throughput

0.594

High

598830

TFDP
Transcription factor Dp

2

1

High-throughput

0.594

High

598836

Q4V6Y7
IP01295p

2

3

High-throughput

0.594

High

598843

Q8IHH3
AT01055p

2

2

High-throughput

0.594

High

598851

SH3G3
Endophilin-A

2

11

High-throughput

0.594

High

598854

Q961D1
Cyclin K, isoform A

2

2

High-throughput

0.594

High

598860

Q9V3M9
Tektin

2

3

High-throughput

0.594

High

598863

Q9VA79
FI06144p

2

1

High-throughput

0.594

High

598868

Q9VBQ3
FI08017p

2

1

High-throughput

0.594

High

598877

Q9VIK7
LD18032p

2

1

High-throughput

0.594

High

598879

Q9VJS5
AT16033p

2

20

High-throughput

0.594

High

598882

Q9VL73
LP20791p

2

1

High-throughput

0.594

High

598883

Q9VLF2
CCR4-NOT transcription complex subunit 9

2

1

High-throughput

0.594

High

598890

BOWEL
Protein bowel

2

3

High-throughput

0.594

High

598892

LIN28
Protein lin-28 homolog

2

2

High-throughput

0.594

High

598900

Q9VWS0
Inhibitor of growth protein

2

1

High-throughput

0.594

High

598907

Q9W2P8
Homeobrain

2

1

High-throughput

0.594

High

598915

Q9XZ57
Eb1, isoform E

2

6

High-throughput

0.594

High

598916

MB21L
Protein mab-21-like

2

1

High-throughput

0.594

High

598806

SUS
Protein suppressor of sable

2

0

High-throughput

0.569

High

598810

DISC
Protein disconnected

2

0

High-throughput

0.569

High

598839

ADRM1
Proteasomal ubiquitin receptor ADRM1 homolog

2

0

High-throughput

0.569

High

598872

Q9VDP8
CG4973 protein

2

0

High-throughput

0.569

High

598873

Q9VDX4
MIP05121p

2

0

High-throughput

0.569

High

598876

MCM10
Protein MCM10 homolog

2

0

High-throughput

0.569

High

485889

AST5
Achaete-scute complex protein T5

1

1

Small-scale

0.552

High

598840

Q7KNM2
Dorsal interacting protein 4

1

20

Small-scale

0.552

High

598822

PROML
Prominin-like protein

2

1

High-throughput

0.542

High

598856

SPIN
Protein spinster

2

1

High-throughput

0.542

High

598857

Q9I7W2
COMM domain-containing protein 3

2

1

High-throughput

0.542

High

598865

KL98A
Kinesin-like protein Klp98A

2

4

High-throughput

0.542

High

598886

POLZ2
DNA polymerase zeta subunit 2

2

1

High-throughput

0.542

High

598896

Q9VW77
IP19827p

2

2

High-throughput

0.542

High

598904

Q9W0B3
GH19706p

2

2

High-throughput

0.542

High

566083

KINH
Kinesin heavy chain

1

2

High-throughput

0.508

High

598811

UBCD1
Ubiquitin-conjugating enzyme E2-17 kDa

1

20

Small-scale

0.508

High

598829

DIAP1
Death-associated inhibitor of apoptosis 1

1

12

High-throughput

0.508

High

598862

CSN7
COP9 signalosome complex subunit 7

1

2

High-throughput

0.508

High

598864

Q9VAA9
JIL-1 anchoring and stabilizing protein, isoform A

1

3

High-throughput

0.508

High

598902

Q9VZY2
Myocardin-related transcription factor, isoform D

1

3

High-throughput

0.508

High

53643

A1Z904
Dystrobrevin

1

4

High-throughput

0.494

High

87072

C6SV46
RE29848p

1

1

High-throughput

0.494

High

116029

M9PHB8
Sarcoplasmic calcium-binding protein, isoform C

1

1

High-throughput

0.494

High

570914

TTKB
Protein tramtrack, beta isoform

1

10

High-throughput

0.494

High

598825

Q058W3
IP14616p

1

1

High-throughput

0.494

High

598828

Q0IGU0
IP21556p

1

13

High-throughput

0.494

High

598833

Q29R02
LD04512p

1

5

High-throughput

0.494

High

598837

Q5BIB4
RE15812p

1

7

High-throughput

0.494

High

598891

Q9VRL1
GEO06356p1

1

20

High-throughput

0.494

High

598912

Q9W4B3
Visual system homeobox 2

1

6

High-throughput

0.494

High

598834

Q29R10
LD24322p

1

0

High-throughput

0.486

High

598850

Q8SX78
LD05679p

1

0

High-throughput

0.486

High

598866

Q9VBJ6
Uncharacterized protein

1

0

High-throughput

0.486

High

598875

Q9VHL0
Hinge2

1

0

High-throughput

0.486

High

598885

Q9VMH2
Actin-related protein 2/3 complex subunit 4

1

0

High-throughput

0.486

High

598887

Q9VPD4
Vesicle transport protein

1

0

High-throughput

0.486

High

332143

O96676
BcDNA.GH12350

1

1

High-throughput

0.481

High

577199

EMS
Homeotic protein empty spiracles

1

7

High-throughput

0.481

High

598820

GSC
Homeobox protein goosecoid

1

6

High-throughput

0.481

High

598827

Q0E9B2
Dystrobrevin

1

4

High-throughput

0.481

High

598838

Q6NNF8
SD21550p

1

1

High-throughput

0.481

High

598846

Q8IQ53
GEO11416p1

1

20

High-throughput

0.481

High

598871

Q9VDN4
Uncharacterized protein, isoform A

1

3

High-throughput

0.481

High

598899

Q9VWP7
C2H2-type domain-containing protein

1

1

High-throughput

0.481

High

598918

X2JDS9
Visual system homeobox 2

1

6

High-throughput

0.481

High

485923

AST4
Achaete-scute complex protein T4

1

3

Small-scale

0.479

High

332419

O97059
Ccp84Ab

1

2

High-throughput

0.464

High

577333

PTC
Protein patched

1

2

High-throughput

0.464

High

598821

CNN
Centrosomin

1

5

High-throughput

0.464

High

598870

Q9VCT6
Uncharacterized protein

1

2

High-throughput

0.464

High

598878

Q9VJM1
GEO13348p1

1

1

High-throughput

0.464

High

598884

SDHF4
Succinate dehydrogenase assembly factor 4, mitochondrial

1

1

High-throughput

0.464

High

598894

Q9VT89
Insulin-like growth factor-binding protein complex acid labile subunit

1

6

High-throughput

0.464

High

598908

Q9W2X3
MIP13962p

1

1

High-throughput

0.464

High

598835

Q2PE13
Activating transcription factor-2

1

0

High-throughput

0.460

High

598852

Q8T476
AT12568p

1

1

High-throughput

0.457

High

46909

A0A4D6K416
Uncharacterized protein, isoform B

1

1

High-throughput

0.451

High

89790

D5A7J7
RH44958p

1

1

High-throughput

0.451

High

598832

Q29QK1
IP05464p

1

1

High-throughput

0.451

High

598841

Q8I942
IP11514p

1

1

High-throughput

0.451

High

598844

Q8INY5
RE08003p1

1

2

High-throughput

0.451

High

598845

Q8INY6
RH05790p

1

2

High-throughput

0.451

High

598849

Q8MKK6
GH04870p

1

3

High-throughput

0.451

High

598910

Q9W481
LD15807p

1

3

High-throughput

0.451

High

53117

A1Z8D5
FI20187p1

1

3

High-throughput

0.439

High

112411

M9MSK1
Uncharacterized protein, isoform B

1

1

High-throughput

0.439

High

598847

Q8IR73
Uncharacterized protein

1

1

High-throughput

0.439

High

598848

Q8IRR4
GM27849p

1

3

High-throughput

0.439

High

598859

Q9V3L8
Ccp84Aa

1

2

High-throughput

0.439

High

598895

Q9VUE1
Histidine-rich glycoprotein

1

1

High-throughput

0.439

High

598897

Q9VWD2
RE70461p

1

1

High-throughput

0.439

High

598917

X2JCJ0
Uncharacterized protein, isoform B

1

1

High-throughput

0.439

High

598919

X2JEH3
Uncharacterized protein, isoform E

1

2

High-throughput

0.439

High

598842

Q8IGE8
RH36596p

1

1

High-throughput

0.417

High

598913

Q9W4I6
Uncharacterized protein, isoform A

1

1

High-throughput

0.417

High

598911

Q9W483
GH18971p

3

0

High-throughput

0.340

High

87091

C6SV53
Bip1, isoform B

2

0

High-throughput

0.310

High

598826

Q058Z8
GEO11848p1

2

0

High-throughput

0.310

High

598855

Q961J0
GH21160p

2

0

High-throughput

0.310

High

598881

Q9VKU4
IP09348p

2

0

High-throughput

0.310

High

598888

Q9VPV6
AT13819p

2

0

High-throughput

0.310

High

598889

Q9VPZ1
GEO12410p1

2

0

High-throughput

0.310

High

598898

MINY3
Ubiquitin carboxyl-terminal hydrolase MINDY-3 homolog

2

0

High-throughput

0.310

High

598901

Q9VZJ1
Protein dpy-30 homolog

2

0

High-throughput

0.310

High

598903

Q9W0A2
MIP23106p

2

0

High-throughput

0.310

High

598906

Q9W2A3
IP10558p

2

0

High-throughput

0.310

High

598816

GRK
Protein gurken

1

0

High-throughput

0.282

High

53250

A1Z8J5
Shavenoid, isoform A

1

0

High-throughput

0.265

Low

186026

SURF4
Surfeit locus protein 4 homolog

1

0

High-throughput

0.265

Low

598813

HYI
Putative hydroxypyruvate isomerase

1

0

High-throughput

0.265

Low

598817

RL9
Large ribosomal subunit protein uL6

1

0

High-throughput

0.265

Low

598861

Q9V3P2
Nucleolar protein 10

1

0

High-throughput

0.265

Low

598867

Q9VBP2
GH01133p

1

0

High-throughput

0.265

Low

598869

Q9VC06
LD37516p

1

0

High-throughput

0.265

Low

598880

Q9VJX2
Uncharacterized protein

1

0

High-throughput

0.265

Low

598914

Q9XZ22
Uncharacterized protein, isoform A

1

0

High-throughput

0.265

Low

55009

A1ZAC0
Transferrin

1

0

High-throughput

0.238

Low

598905

Q9W0Z5
LP09747p

1

0

High-throughput

0.238

Low


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Last updated: 15 Jul 2024