Protein: CBX2
Chromobox protein homolog 2

Gene: CBX2
Organism: Homo sapiens
Interactions: 124
UniProt ID: Q14781

Gene Ontology (top 5):
GO:0000122 - negative regulation of transcription by RNA polymerase II
GO:0000791 - euchromatin
GO:0000792 - heterochromatin
GO:0003677 - DNA binding
GO:0003682 - chromatin binding

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

1059184

RING2
E3 ubiquitin-protein ligase RING2

10

20

Small-scale

0.976

High

717831

BMI1
Polycomb complex protein BMI-1

10

20

Small-scale

0.973

High

718398

PCGF2
Polycomb group RING finger protein 2

9

20

Small-scale

0.972

High

987972

RING1
E3 ubiquitin-protein ligase RING1

5

20

Small-scale

0.924

High

123249

CBX4
E3 SUMO-protein ligase CBX4

4

17

Small-scale

0.873

High

1059196

CBX8
Chromobox protein homolog 8

2

18

Small-scale

0.754

High

943062

PHC1
Polyhomeotic-like protein 1

6

20

Small-scale

0.733

High

1059170

PHC2
Polyhomeotic-like protein 2

6

20

Small-scale

0.732

High

1059186

MDFI
MyoD family inhibitor

4

1

High-throughput

0.703

High

898909

PSME3
Proteasome activator complex subunit 3

4

1

High-throughput

0.699

High

931637

CSK2B
Casein kinase II subunit beta

4

4

Small-scale

0.694

High

1059177

PHC3
Polyhomeotic-like protein 3

4

20

Small-scale

0.686

High

934768

H31
Histone H3.1

4

20

Small-scale

0.682

High

1059153

RBY1F
RNA-binding motif protein, Y chromosome, family 1 member F/J

3

4

High-throughput

0.675

High

952341

H33
Histone H3.3

3

20

Small-scale

0.650

High

918366

H2B1C
Histone H2B type 1-C/E/F/G/I

3

20

High-throughput

0.633

High

1059207

LMBL1
Lethal(3)malignant brain tumor-like protein 1

2

20

High-throughput

0.628

High

1059175

RYBP
RING1 and YY1-binding protein

2

12

Small-scale

0.624

High

316035

CBX6
Chromobox protein homolog 6

1

19

High-throughput

0.618

High

1059151

CBX2
Chromobox protein homolog 2

1

18

Small-scale

0.618

High

1059156

PCGF3
Polycomb group RING finger protein 3

1

20

High-throughput

0.618

High

1059168

PCGF5
Polycomb group RING finger protein 5

1

20

High-throughput

0.618

High

1059189

PCGF1
Polycomb group RING finger protein 1

1

20

High-throughput

0.618

High

1059190

PCGF6
Polycomb group RING finger protein 6

1

20

High-throughput

0.618

High

1059162

DHX57
Putative ATP-dependent RNA helicase DHX57

3

7

High-throughput

0.616

High

455449

PARP1
Poly [ADP-ribose] polymerase 1

2

16

High-throughput

0.611

High

586751

CSK22
Casein kinase II subunit alpha'

2

10

Small-scale

0.611

High

934172

CSK21
Casein kinase II subunit alpha

2

10

Small-scale

0.611

High

1059176

BOLL
Protein boule-like

2

4

High-throughput

0.606

High

575051

RL7
Large ribosomal subunit protein uL30

2

0

High-throughput

0.602

High

1059179

UBP7
Ubiquitin carboxyl-terminal hydrolase 7

2

9

Small-scale

0.584

High

1059202

SCML1
Sex comb on midleg-like protein 1

2

20

High-throughput

0.584

High

1059164

RBPS2
RNA-binding protein with multiple splicing 2

2

0

High-throughput

0.580

High

1059154

H31T
Histone H3.1t

2

20

Small-scale

0.578

High

483439

RBY1A
RNA-binding motif protein, Y chromosome, family 1 member A1

1

4

High-throughput

0.573

High

1059165

H32
Histone H3.2

1

20

Small-scale

0.568

High

887356

KR122
Keratin-associated protein 12-2

2

10

High-throughput

0.553

High

888533

KR123
Keratin-associated protein 12-3

2

1

High-throughput

0.553

High

1059191

KRA44
Keratin-associated protein 4-4

2

10

High-throughput

0.553

High

1059180

TRI63
E3 ubiquitin-protein ligase TRIM63

1

13

High-throughput

0.541

High

1059192

TRI55
Tripartite motif-containing protein 55

1

20

High-throughput

0.541

High

270634

MYCB2
E3 ubiquitin-protein ligase MYCBP2

1

3

High-throughput

0.536

High

391702

H2A1B
Histone H2A type 1-B/E

1

20

High-throughput

0.536

High

418283

NPM
Nucleophosmin

1

3

High-throughput

0.536

High

470020

H2AZ
Histone H2A.Z

1

20

High-throughput

0.536

High

508528

TOP1
DNA topoisomerase 1

1

7

High-throughput

0.536

High

564901

HMGA1
High mobility group protein HMG-I/HMG-Y

1

5

High-throughput

0.536

High

595229

LMNB1
Lamin-B1

1

7

High-throughput

0.536

High

818053

SOX2
Transcription factor SOX-2

1

16

High-throughput

0.536

High

917274

H4
Histone H4

1

15

High-throughput

0.536

High

942161

GTF2I
General transcription factor II-I

1

2

High-throughput

0.536

High

948791

HMGN5
High mobility group nucleosome-binding domain-containing protein 5

1

7

High-throughput

0.536

High

969586

CENPE
Centromere-associated protein E

1

2

High-throughput

0.536

High

996672

SSRP1
FACT complex subunit SSRP1

1

20

High-throughput

0.536

High

1059152

NUMA1
Nuclear mitotic apparatus protein 1

1

12

High-throughput

0.536

High

1059155

H2B2E
Histone H2B type 2-E

1

20

High-throughput

0.536

High

1059157

DCAF6
DDB1- and CUL4-associated factor 6

1

14

High-throughput

0.536

High

1059166

NUFP2
FMR1-interacting protein NUFIP2

1

3

High-throughput

0.536

High

1059182

SCMH1
Polycomb protein SCMH1

1

20

High-throughput

0.536

High

1059188

PLCD4
1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase delta-4

1

1

High-throughput

0.536

High

1059193

PAR12
Protein mono-ADP-ribosyltransferase PARP12

1

5

High-throughput

0.536

High

1059199

ZKSC7
Zinc finger protein with KRAB and SCAN domains 7

1

20

High-throughput

0.536

High

1059208

KDM3A
Lysine-specific demethylase 3A

1

15

High-throughput

0.536

High

473281

KRA23
Keratin-associated protein 2-3

1

10

High-throughput

0.523

High

889246

KR107
Keratin-associated protein 10-7

1

8

High-throughput

0.523

High

889760

KR109
Keratin-associated protein 10-9

1

9

High-throughput

0.523

High

959931

TF2B
Transcription initiation factor IIB

1

1

High-throughput

0.515

High

1025750

TADBP
TAR DNA-binding protein 43

1

3

High-throughput

0.515

High

1059161

Q6FHY5
MEOX2 protein

1

4

High-throughput

0.515

High

1059167

SPRE1
Sprouty-related, EVH1 domain-containing protein 1

1

1

High-throughput

0.515

High

1059209

TF3C3
General transcription factor 3C polypeptide 3

1

1

High-throughput

0.515

High

1059187

KR412
Keratin-associated protein 4-12

1

10

High-throughput

0.494

High

870647

SYYC
Tyrosine--tRNA ligase, cytoplasmic

1

0

High-throughput

0.493

High

165793

TRNK1
TPR and ankyrin repeat-containing protein 1

1

1

High-throughput

0.489

High

591330

TNR1B
Tumor necrosis factor receptor superfamily member 1B

1

3

High-throughput

0.489

High

1059159

CD158
Coiled-coil domain-containing protein 158

1

2

High-throughput

0.489

High

1059160

RN213
E3 ubiquitin-protein ligase RNF213

1

2

High-throughput

0.489

High

1059173

DI3L2
DIS3-like exonuclease 2

1

1

High-throughput

0.489

High

1059203

ANR26
Ankyrin repeat domain-containing protein 26

1

4

High-throughput

0.489

High

837975

MEOX2
Homeobox protein MOX-2

1

4

High-throughput

0.481

High

179640

RPA34
DNA-directed RNA polymerase I subunit RPA34

1

10

High-throughput

0.479

High

239344

CC14B
Dual specificity protein phosphatase CDC14B

1

4

High-throughput

0.479

High

265649

E2F6
Transcription factor E2F6

1

10

High-throughput

0.479

High

319841

HERC2
E3 ubiquitin-protein ligase HERC2

1

2

High-throughput

0.479

High

346802

MYC
Myc proto-oncogene protein

1

20

High-throughput

0.479

High

374242

RAF1
RAF proto-oncogene serine/threonine-protein kinase

1

6

High-throughput

0.479

High

652857

APEX1
DNA repair nuclease/redox regulator APEX1

1

1

High-throughput

0.479

High

707633

H2B1B
Histone H2B type 1-B

1

20

High-throughput

0.479

High

828230

CENPA
Histone H3-like centromeric protein A

1

20

High-throughput

0.479

High

850048

UBP11
Ubiquitin carboxyl-terminal hydrolase 11

1

14

Small-scale

0.479

High

928911

SKP1
S-phase kinase-associated protein 1

1

2

High-throughput

0.479

High

959422

VIGLN
Vigilin

1

11

High-throughput

0.479

High

967872

PO5F1
POU domain, class 5, transcription factor 1

1

3

High-throughput

0.479

High

1056829

MDC1
Mediator of DNA damage checkpoint protein 1

1

14

High-throughput

0.479

High

1059158

BCORL
BCL-6 corepressor-like protein 1

1

13

High-throughput

0.479

High

1059163

BCOR
BCL-6 corepressor

1

20

High-throughput

0.479

High

1059169

MGAP
MAX gene-associated protein

1

9

High-throughput

0.479

High

1059171

SMC5
Structural maintenance of chromosomes protein 5

1

11

High-throughput

0.479

High

1059172

YAF2
YY1-associated factor 2

1

12

High-throughput

0.479

High

1059174

PELP1
Proline-, glutamic acid- and leucine-rich protein 1

1

15

Small-scale

0.479

High

1059178

KDM2B
Lysine-specific demethylase 2B

1

10

High-throughput

0.479

High

1059181

SNR40
U5 small nuclear ribonucleoprotein 40 kDa protein

1

16

High-throughput

0.479

High

1059185

FEV
Protein FEV

1

2

High-throughput

0.479

High

1059194

NANOG
Homeobox protein NANOG

1

6

High-throughput

0.479

High

1059197

MDN1
Midasin

1

1

Small-scale

0.479

High

1059198

TE2IP
Telomeric repeat-binding factor 2-interacting protein 1

1

3

High-throughput

0.479

High

1059201

DAXX
Death domain-associated protein 6

1

5

Small-scale

0.479

High

1059204

SCML2
Sex comb on midleg-like protein 2

1

20

Small-scale

0.479

High

1059206

ZN330
Zinc finger protein 330

1

4

High-throughput

0.479

High

1059210

RT18B
Small ribosomal subunit protein mS40

1

1

High-throughput

0.479

High

103738

G5E9A7
DM1 locus, WD repeat containing

1

10

High-throughput

0.470

High

338441

EGFR
Epidermal growth factor receptor

1

0

High-throughput

0.458

High

658502

TEAD1
Transcriptional enhancer factor TEF-1

1

0

High-throughput

0.458

High

1059205

ASF1A
Histone chaperone ASF1A

1

0

High-throughput

0.458

High

888690

KR101
Keratin-associated protein 10-1

1

9

High-throughput

0.439

High

888870

KR103
Keratin-associated protein 10-3

1

10

High-throughput

0.439

High

1059195

FBRS
Probable fibrosin-1

1

6

High-throughput

0.437

High

67076

CRTP1
Cysteine-rich tail protein 1

2

0

High-throughput

0.316

High

1059200

SPAT7
Spermatogenesis-associated protein 7

1

0

High-throughput

0.279

Low

1059211

KCNE3
Potassium voltage-gated channel subfamily E member 3

1

0

High-throughput

0.279

Low

47223

A0A6Q8PF08
Peripheral myelin protein 22

1

0

High-throughput

0.268

Low

100767

APRIO
Alternative prion protein

1

0

High-throughput

0.249

Low

1059183

DDRGK
DDRGK domain-containing protein 1

1

0

High-throughput

0.249

Low


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Last updated: 15 Jul 2024