Protein: TRM61
tRNA (adenine(58)-N(1))-methyltransferase catalytic subunit TRMT61A (EC 2.1.1.220) (mRNA methyladenosine-N(1)-methyltransferase catalytic subunit TRMT61A) (EC 2.1.1.-) (tRNA(m1A58)-methyltransferase subunit TRMT61A) (tRNA(m1A58)MTase subunit TRMT61A)

Gene: TRM61, TRMT61A
Organism: Homo sapiens
Interactions: 59
UniProt ID: Q96FX7

Gene Ontology (top 5):
GO:0005634 - nucleus
GO:0005654 - nucleoplasm
GO:0030488 - tRNA methylation
GO:0031515 - tRNA (m1A) methyltransferase complex
GO:0061953 - mRNA (adenine-N1-)-methyltransferase activity

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

1291643

TRM6
tRNA

4

2

Small-scale

0.895

High

167104

ARHGB
Rho guanine nucleotide exchange factor 11

3

1

High-throughput

0.667

High

198953

RFOX2
RNA binding protein fox-1 homolog 2

3

0

High-throughput

0.638

High

1050748

FHL2
Four and a half LIM domains protein 2

3

0

High-throughput

0.638

High

1291640

ARHGC
Rho guanine nucleotide exchange factor 12

3

1

High-throughput

0.609

High

1039145

KCC2D
Calcium/calmodulin-dependent protein kinase type II subunit delta

2

0

High-throughput

0.602

High

880317

TCL1A
T-cell leukemia/lymphoma protein 1A

2

0

High-throughput

0.580

High

213904

DYRK3
Dual specificity tyrosine-phosphorylation-regulated kinase 3

1

3

High-throughput

0.536

High

403310

LA
Lupus La protein

1

1

High-throughput

0.536

High

1038623

HDAC1
Histone deacetylase 1

1

1

High-throughput

0.536

High

1291636

TF7L2
Transcription factor 7-like 2

1

1

High-throughput

0.536

High

1175095

TBA1A
Tubulin alpha-1A chain

1

0

High-throughput

0.513

High

1202049

CAND1
Cullin-associated NEDD8-dissociated protein 1

1

0

High-throughput

0.513

High

1259895

TF3C2
General transcription factor 3C polypeptide 2

1

0

High-throughput

0.513

High

1271121

N42L2
NEDD4-binding protein 2-like 2

1

0

High-throughput

0.513

High

1272526

CSN5
COP9 signalosome complex subunit 5

1

0

High-throughput

0.513

High

1291631

TCAB1
Telomerase Cajal body protein 1

1

0

High-throughput

0.513

High

1291633

PLK3
Serine/threonine-protein kinase PLK3

1

0

High-throughput

0.513

High

1291637

SNRK
SNF-related serine/threonine-protein kinase

1

0

High-throughput

0.513

High

1291638

RNF12
E3 ubiquitin-protein ligase RLIM

1

0

High-throughput

0.513

High

770977

TCPZ
T-complex protein 1 subunit zeta

1

2

High-throughput

0.489

High

943406

TCPB
T-complex protein 1 subunit beta

1

1

High-throughput

0.489

High

1077854

MYLK
Myosin light chain kinase, smooth muscle

1

1

High-throughput

0.489

High

1266392

TCPW
T-complex protein 1 subunit zeta-2

1

2

High-throughput

0.489

High

1291644

MAST1
Microtubule-associated serine/threonine-protein kinase 1

1

1

High-throughput

0.489

High

818343

SOX2
Transcription factor SOX-2

1

1

High-throughput

0.479

High

935106

H31
Histone H3.1

1

2

High-throughput

0.479

High

952543

H33
Histone H3.3

1

2

High-throughput

0.479

High

1291641

ZRAN1
Ubiquitin thioesterase ZRANB1

1

1

High-throughput

0.479

High

374683

RAF1
RAF proto-oncogene serine/threonine-protein kinase

1

0

High-throughput

0.458

High

553424

RFA2
Replication protein A 32 kDa subunit

1

0

High-throughput

0.458

High

651942

RFA1
Replication protein A 70 kDa DNA-binding subunit

1

0

High-throughput

0.458

High

721145

RFA3
Replication protein A 14 kDa subunit

1

0

High-throughput

0.458

High

1085879

IF16
Gamma-interferon-inducible protein 16

1

0

High-throughput

0.458

High

1236433

SIR6
NAD-dependent protein deacylase sirtuin-6

1

0

High-throughput

0.458

High

1291634

NANOG
Homeobox protein NANOG

1

0

High-throughput

0.458

High

1291635

BRD7
Bromodomain-containing protein 7

1

0

High-throughput

0.458

High

402345

JUN
Transcription factor Jun

1

0

High-throughput

0.426

High

789172

HELZ
Probable helicase with zinc finger domain

1

0

High-throughput

0.426

High

670580

PBLD
Phenazine biosynthesis-like domain-containing protein

3

0

High-throughput

0.347

High

828866

SRP09
Signal recognition particle 9 kDa protein

2

0

High-throughput

0.328

High

1291642

EVL
Ena/VASP-like protein

2

0

High-throughput

0.328

High

200654

CP110
Centriolar coiled-coil protein of 110 kDa

1

0

High-throughput

0.279

Low

225020

ZNRD2
Protein ZNRD2

1

0

High-throughput

0.279

Low

309512

MTMR5
Myotubularin-related protein 5

1

0

High-throughput

0.279

Low

687029

GRK4
G protein-coupled receptor kinase 4

1

0

High-throughput

0.279

Low

1114186

TBB8
Tubulin beta-8 chain

1

0

High-throughput

0.279

Low

1121486

KLH26
Kelch-like protein 26

1

0

High-throughput

0.279

Low

1150627

MRCKG
Serine/threonine-protein kinase MRCK gamma

1

0

High-throughput

0.279

Low

1162292

WDR59
GATOR2 complex protein WDR59

1

0

High-throughput

0.279

Low

1163793

RICTR
Rapamycin-insensitive companion of mTOR

1

0

High-throughput

0.279

Low

1291630

TCPH
T-complex protein 1 subunit eta

1

0

High-throughput

0.279

Low

1291632

EIF2A
Eukaryotic translation initiation factor 2A

1

0

High-throughput

0.279

Low

1291645

EMIL1
EMILIN-1

1

0

High-throughput

0.279

Low

1171211

TRI67
Tripartite motif-containing protein 67

1

0

High-throughput

0.249

Low

1281549

MYDGF
Myeloid-derived growth factor

1

0

High-throughput

0.249

Low

600648

EPHA1
Ephrin type-A receptor 1

1

0

High-throughput

0.238

Low

47687

A0AUL9
ATG2A protein

1

0

High-throughput

0.232

Low

1291639

USE1
Vesicle transport protein USE1

1

0

Small-scale

0.232

Low


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Last updated: 15 Jul 2024