Protein: CLPB
Mitochondrial disaggregase (EC 3.6.1.-) (Suppressor of potassium transport defect 3) [Cleaved into: Mitochondrial disaggregase, cleaved form]

Gene: CLPB
Organism: Homo sapiens
Interactions: 208
UniProt ID: Q9H078

Gene Ontology (top 5):
GO:0005524 - ATP binding
GO:0005737 - cytoplasm
GO:0005739 - mitochondrion
GO:0005758 - mitochondrial intermembrane space
GO:0016887 - ATP hydrolysis activity

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

154237

CHK1
Serine/threonine-protein kinase Chk1

3

0

High-throughput

0.803

High

1260291

PTPM1
Phosphatidylglycerophosphatase and protein-tyrosine phosphatase 1

2

3

High-throughput

0.754

High

374846

RAF1
RAF proto-oncogene serine/threonine-protein kinase

2

1

High-throughput

0.737

High

548125

UCHL3
Ubiquitin carboxyl-terminal hydrolase isozyme L3

4

1

High-throughput

0.697

High

153169

MP2K7
Dual specificity mitogen-activated protein kinase kinase 7

1

3

High-throughput

0.691

High

270443

KS6A5
Ribosomal protein S6 kinase alpha-5

1

1

High-throughput

0.691

High

609695

KAPCG
cAMP-dependent protein kinase catalytic subunit gamma

1

2

High-throughput

0.691

High

794421

GRK6
G protein-coupled receptor kinase 6

1

3

High-throughput

0.691

High

851679

NEK4
Serine/threonine-protein kinase Nek4

1

2

High-throughput

0.691

High

871473

AAPK2
5'-AMP-activated protein kinase catalytic subunit alpha-2

1

2

High-throughput

0.691

High

1315121

TSSK6
Testis-specific serine/threonine-protein kinase 6

1

2

High-throughput

0.691

High

1315491

PINK1
Serine/threonine-protein kinase PINK1, mitochondrial

1

2

High-throughput

0.691

High

1327251

NRBP2
Nuclear receptor-binding protein 2

1

5

High-throughput

0.691

High

1327264

DD19B
ATP-dependent RNA helicase DDX19B

1

3

High-throughput

0.691

High

1327266

MOK
MAPK/MAK/MRK overlapping kinase

1

4

High-throughput

0.665

High

1327265

TTF2
Transcription termination factor 2

3

7

Small-scale

0.664

High

848472

IRAK1
Interleukin-1 receptor-associated kinase 1

1

0

High-throughput

0.656

High

1042502

CUL3
Cullin-3

3

2

High-throughput

0.650

High

325383

AIFM1
Apoptosis-inducing factor 1, mitochondrial

3

3

High-throughput

0.643

High

59638

GTPBA
GTP-binding protein 10

2

5

High-throughput

0.628

High

256674

CLU
Clustered mitochondria protein homolog

2

3

High-throughput

0.628

High

803228

IF2M
Translation initiation factor IF-2, mitochondrial

2

12

High-throughput

0.628

High

873873

IF5
Eukaryotic translation initiation factor 5

2

4

High-throughput

0.628

High

1065718

SETB1
Histone-lysine N-methyltransferase SETDB1

2

1

High-throughput

0.628

High

1327236

SRMS
Tyrosine-protein kinase Srms

2

1

High-throughput

0.628

High

1327267

EXOG
Nuclease EXOG, mitochondrial

2

1

High-throughput

0.628

High

118442

HAX1
HCLS1-associated protein X-1

3

0

Small-scale

0.628

High

656080

PSB8
Proteasome subunit beta type-8

1

2

High-throughput

0.618

High

813736

CAPZB
F-actin-capping protein subunit beta

1

3

High-throughput

0.618

High

149267

CTRO
Citron Rho-interacting kinase

1

3

High-throughput

0.618

High

295240

RECQ4
ATP-dependent DNA helicase Q4

1

3

High-throughput

0.618

High

519824

KCRU
Creatine kinase U-type, mitochondrial

1

1

High-throughput

0.618

High

737476

LONM
Lon protease homolog, mitochondrial

1

8

High-throughput

0.618

High

1171634

TRI67
Tripartite motif-containing protein 67

1

6

High-throughput

0.618

High

1184026

DHX30
ATP-dependent RNA helicase DHX30

1

3

High-throughput

0.618

High

1292208

AURKB
Aurora kinase B

1

3

High-throughput

0.618

High

1303097

YMEL1
ATP-dependent zinc metalloprotease YME1L1

1

5

High-throughput

0.618

High

1313927

DUS23
Dual specificity protein phosphatase 23

1

3

High-throughput

0.618

High

1317402

STK33
Serine/threonine-protein kinase 33

1

2

High-throughput

0.618

High

1327237

Q9H4D1
Protein kinase

1

2

High-throughput

0.618

High

1327239

DUS21
Dual specificity protein phosphatase 21

1

1

High-throughput

0.618

High

1327249

DUS22
Dual specificity protein phosphatase 22

1

1

High-throughput

0.618

High

1327259

PAK5
Serine/threonine-protein kinase PAK 5

1

4

High-throughput

0.618

High

1327271

AFG32
Mitochondrial inner membrane m-AAA protease component AFG3L2

1

6

High-throughput

0.618

High

1191376

ADCK2
Uncharacterized aarF domain-containing protein kinase 2

2

5

High-throughput

0.611

High

1287836

COQ8B
Atypical kinase COQ8B, mitochondrial

2

5

High-throughput

0.611

High

962965

MDM2
E3 ubiquitin-protein ligase Mdm2

2

0

High-throughput

0.602

High

1283705

P33MX
Putative monooxygenase p33MONOX

2

0

High-throughput

0.602

High

1290882

TRI11
E3 ubiquitin-protein ligase TRIM11

2

0

High-throughput

0.602

High

228633

PRKN
E3 ubiquitin-protein ligase parkin

2

9

High-throughput

0.584

High

231155

OPA1
Dynamin-like GTPase OPA1, mitochondrial

2

3

Small-scale

0.584

High

266812

NDUS3
NADH dehydrogenase [ubiquinone] iron-sulfur protein 3, mitochondrial

2

1

High-throughput

0.584

High

525636

COX41
Cytochrome c oxidase subunit 4 isoform 1, mitochondrial

2

1

High-throughput

0.584

High

1327243

SFXN1
Sideroflexin-1

2

2

High-throughput

0.584

High

883640

RIPK4
Receptor-interacting serine/threonine-protein kinase 4

1

2

High-throughput

0.575

High

862246

ARFP1
Arfaptin-1

2

1

High-throughput

0.574

High

1327252

PHAG1
Phosphoprotein associated with glycosphingolipid-enriched microdomains 1

2

1

High-throughput

0.574

High

370396

ESR1
Estrogen receptor

2

4

High-throughput

0.571

High

1306240

MDFI
MyoD family inhibitor

1

1

High-throughput

0.560

High

900878

RHOA
Transforming protein RhoA

1

11

High-throughput

0.553

High

951316

RHOG
Rho-related GTP-binding protein RhoG

1

8

High-throughput

0.553

High

1327270

TRRAP
Transformation/transcription domain-associated protein

1

6

High-throughput

0.553

High

272388

MTU1
Mitochondrial tRNA-specific 2-thiouridylase 1

1

1

High-throughput

0.536

High

313146

MOCS3
Adenylyltransferase and sulfurtransferase MOCS3

1

4

High-throughput

0.536

High

455852

PARP1
Poly [ADP-ribose] polymerase 1

1

1

High-throughput

0.536

High

504728

HSP7C
Heat shock cognate 71 kDa protein

1

2

High-throughput

0.536

High

871771

HSP72
Heat shock-related 70 kDa protein 2

1

4

High-throughput

0.536

High

1161341

VIP1
Inositol hexakisphosphate and diphosphoinositol-pentakisphosphate kinase 1

1

2

High-throughput

0.536

High

1170511

S2548
Solute carrier family 25 member 48

1

5

High-throughput

0.536

High

1299359

RBM14
RNA-binding protein 14

1

2

High-throughput

0.536

High

1310628

ZNG1A
Zinc-regulated GTPase metalloprotein activator 1A

1

1

High-throughput

0.536

High

1327255

OCAD1
OCIA domain-containing protein 1

2

1

High-throughput

0.533

High

1173921

UBP30
Ubiquitin carboxyl-terminal hydrolase 30

1

2

High-throughput

0.515

High

1184975

CSN6
COP9 signalosome complex subunit 6

1

1

High-throughput

0.515

High

64068

AQ12B
Aquaporin-12B

1

0

High-throughput

0.513

High

983073

ICA69
Islet cell autoantigen 1

1

0

High-throughput

0.513

High

1246522

PPTC7
Protein phosphatase PTC7 homolog

1

0

High-throughput

0.513

High

1327258

NDUAD
NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 13

1

0

High-throughput

0.513

High

1327261

MTFP1
Mitochondrial fission process protein 1

1

0

High-throughput

0.513

High

1327263

TPC2L
Trafficking protein particle complex subunit 2-like protein

1

0

High-throughput

0.513

High

151899

IRS4
Insulin receptor substrate 4

1

1

High-throughput

0.489

High

165044

SC16A
Protein transport protein Sec16A

1

4

High-throughput

0.489

High

215854

ANGL7
Angiopoietin-related protein 7

1

3

High-throughput

0.489

High

538768

HXB1
Homeobox protein Hox-B1

1

2

High-throughput

0.489

High

726543

TIMP3
Metalloproteinase inhibitor 3

1

1

High-throughput

0.489

High

1067612

P2RY6
P2Y purinoceptor 6

1

1

High-throughput

0.489

High

1221215

CMA1C
Protein CIMAP1C

1

1

High-throughput

0.489

High

1237291

STPG3
Protein STPG3

1

1

High-throughput

0.489

High

1288027

HDA11
Histone deacetylase 11

1

3

High-throughput

0.489

High

1298855

NP1L5
Nucleosome assembly protein 1-like 5

1

1

High-throughput

0.489

High

1299990

PUS7
Pseudouridylate synthase 7 homolog

1

1

High-throughput

0.489

High

171446

SMAD9
Mothers against decapentaplegic homolog 9

1

0

High-throughput

0.486

High

121365

NDUS8
NADH dehydrogenase [ubiquinone] iron-sulfur protein 8, mitochondrial

1

1

High-throughput

0.479

High

163251

XPO1
Exportin-1

1

4

High-throughput

0.479

High

204049

HTRA2
Serine protease HTRA2, mitochondrial

1

4

High-throughput

0.479

High

258524

COQ9
Ubiquinone biosynthesis protein COQ9, mitochondrial

1

1

High-throughput

0.479

High

274622

S2512
Electrogenic aspartate/glutamate antiporter SLC25A12, mitochondrial

1

4

High-throughput

0.479

High

276878

SCO1
Protein SCO1 homolog, mitochondrial

1

2

High-throughput

0.479

High

327558

TRUB2
Pseudouridylate synthase TRUB2, mitochondrial

1

3

High-throughput

0.479

High

385490

NTRK1
High affinity nerve growth factor receptor

1

3

High-throughput

0.479

High

540758

CX6B1
Cytochrome c oxidase subunit 6B1

1

1

High-throughput

0.479

High

658158

NDUS1
NADH-ubiquinone oxidoreductase 75 kDa subunit, mitochondrial

1

2

High-throughput

0.479

High

739278

ODO2
Dihydrolipoyllysine-residue succinyltransferase component of 2-oxoglutarate dehydrogenase complex, mitochondrial

1

4

High-throughput

0.479

High

832710

MCM2
DNA replication licensing factor MCM2

1

4

High-throughput

0.479

High

833116

ACOT2
Acyl-coenzyme A thioesterase 2, mitochondrial

1

2

High-throughput

0.479

High

846222

RT29
Small ribosomal subunit protein mS29

1

1

High-throughput

0.479

High

879942

NDUV3
NADH dehydrogenase [ubiquinone] flavoprotein 3, mitochondrial

1

1

High-throughput

0.479

High

946962

RT22
Small ribosomal subunit protein mS22

1

1

High-throughput

0.479

High

947659

RT05
Small ribosomal subunit protein uS5m

1

4

High-throughput

0.479

High

948354

RT34
Small ribosomal subunit protein mS34

1

1

High-throughput

0.479

High

948706

RT09
Small ribosomal subunit protein uS9m

1

2

High-throughput

0.479

High

949165

LACTB
Serine beta-lactamase-like protein LACTB, mitochondrial

1

1

High-throughput

0.479

High

999072

EP300
Histone acetyltransferase p300

1

5

High-throughput

0.479

High

1020550

TRAP1
Heat shock protein 75 kDa, mitochondrial

1

5

High-throughput

0.479

High

1036060

BIRC3
Baculoviral IAP repeat-containing protein 3

1

2

High-throughput

0.479

High

1081397

E2F4
Transcription factor E2F4

1

2

High-throughput

0.479

High

1088637

MIC60
MICOS complex subunit MIC60

1

1

High-throughput

0.479

High

1102065

ERC6L
DNA excision repair protein ERCC-6-like

1

9

High-throughput

0.479

High

1183690

TM10C
tRNA methyltransferase 10 homolog C

1

1

Small-scale

0.479

High

1185364

FAKD5
FAST kinase domain-containing protein 5, mitochondrial

1

2

High-throughput

0.479

High

1246641

COQ8A
Atypical kinase COQ8A, mitochondrial

1

5

High-throughput

0.479

High

1266955

RT27
Small ribosomal subunit protein mS27

1

1

High-throughput

0.479

High

1268781

RT31
Small ribosomal subunit protein mS31

1

1

High-throughput

0.479

High

1269565

ESR2
Estrogen receptor beta

1

4

High-throughput

0.479

High

1283486

MFRN2
Mitoferrin-2

1

5

High-throughput

0.479

High

1285861

COA7
Cytochrome c oxidase assembly factor 7

1

4

High-throughput

0.479

High

1289293

OMA1
Metalloendopeptidase OMA1, mitochondrial

1

1

High-throughput

0.479

High

1290621

PTCD3
Small ribosomal subunit protein mS39

1

1

High-throughput

0.479

High

1297457

IMP1L
Mitochondrial inner membrane protease subunit 1

1

2

High-throughput

0.479

High

1305250

PHB2
Prohibitin-2

1

5

High-throughput

0.479

High

1317115

RT26
Small ribosomal subunit protein mS26

1

1

High-throughput

0.479

High

1319002

AMRA1
Activating molecule in BECN1-regulated autophagy protein 1

1

7

High-throughput

0.479

High

1327234

S2551
Mitochondrial nicotinamide adenine dinucleotide transporter SLC25A51

1

4

High-throughput

0.479

High

1327238

PKHA4
Pleckstrin homology domain-containing family A member 4

1

4

High-throughput

0.479

High

1327250

SYIM
Isoleucine--tRNA ligase, mitochondrial

1

6

High-throughput

0.479

High

1327254

RMND1
Required for meiotic nuclear division protein 1 homolog

1

2

High-throughput

0.479

High

1327262

ZRAN1
Ubiquitin thioesterase ZRANB1

1

1

High-throughput

0.479

High

1327269

RT02
Small ribosomal subunit protein uS2m

1

8

High-throughput

0.479

High

1327272

SAM50
Sorting and assembly machinery component 50 homolog

1

2

High-throughput

0.479

High

1243842

KMT2C
Histone-lysine N-methyltransferase 2C

1

2

High-throughput

0.470

High

1297246

DJC30
DnaJ homolog subfamily C member 30, mitochondrial

1

8

High-throughput

0.470

High

1315196

OSB10
Oxysterol-binding protein-related protein 10

1

4

High-throughput

0.470

High

50400

NDUF8
NADH dehydrogenase [ubiquinone] 1 alpha subcomplex assembly factor 8

1

0

High-throughput

0.458

High

130591

NDUA4
Cytochrome c oxidase subunit NDUFA4

1

0

High-throughput

0.458

High

264626

MTX2
Metaxin-2

1

0

High-throughput

0.458

High

323111

STAU1
Double-stranded RNA-binding protein Staufen homolog 1

1

0

High-throughput

0.458

High

473415

CISD3
CDGSH iron-sulfur domain-containing protein 3, mitochondrial

1

0

High-throughput

0.458

High

780072

CCNF
Cyclin-F

1

0

High-throughput

0.458

High

851968

NDUA8
NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 8

1

0

High-throughput

0.458

High

1074652

SURF1
Surfeit locus protein 1

1

0

High-throughput

0.458

High

1086081

CDKN3
Cyclin-dependent kinase inhibitor 3

1

0

High-throughput

0.458

High

1183217

COX15
Heme A synthase COX15

1

0

High-throughput

0.458

High

1260244

CEMIP
Cell migration-inducing and hyaluronan-binding protein

1

0

Small-scale

0.458

High

1264596

CHC10
Coiled-coil-helix-coiled-coil-helix domain-containing protein 10, mitochondrial

1

0

High-throughput

0.458

High

1281844

FBX32
F-box only protein 32

1

0

High-throughput

0.458

High

1286188

F136A
Protein FAM136A

1

0

High-throughput

0.458

High

1294347

COX14
Cytochrome c oxidase assembly protein COX14

1

0

High-throughput

0.458

High

1311091

TIM29
Mitochondrial import inner membrane translocase subunit Tim29

1

0

High-throughput

0.458

High

1312491

DHRS4
Dehydrogenase/reductase SDR family member 4

1

0

High-throughput

0.458

High

1313257

MIC26
MICOS complex subunit MIC26

1

0

High-throughput

0.458

High

1327235

PARL
Presenilin-associated rhomboid-like protein, mitochondrial

1

0

High-throughput

0.458

High

1327240

OPA3
Optic atrophy 3 protein

1

0

High-throughput

0.458

High

1327241

EGLN3
Prolyl hydroxylase EGLN3

1

0

High-throughput

0.458

High

1327242

CQ10B
Coenzyme Q-binding protein COQ10 homolog B, mitochondrial

1

0

High-throughput

0.458

High

1327244

ZFYV1
Zinc finger FYVE domain-containing protein 1

1

0

Small-scale

0.458

High

1327248

DBLOH
Diablo IAP-binding mitochondrial protein

1

0

High-throughput

0.458

High

1327253

MCUB
Calcium uniporter regulatory subunit MCUb, mitochondrial

1

0

High-throughput

0.458

High

1327256

MIC19
MICOS complex subunit MIC19

1

0

High-throughput

0.458

High

1327273

TIM13
Mitochondrial import inner membrane translocase subunit Tim13

1

0

High-throughput

0.458

High

175191

OGT1
UDP-N-acetylglucosamine--peptide N-acetylglucosaminyltransferase 110 kDa subunit

1

2

High-throughput

0.457

High

442481

RU17
U1 small nuclear ribonucleoprotein 70 kDa

1

1

High-throughput

0.437

High

652197

RFA1
Replication protein A 70 kDa DNA-binding subunit

1

5

High-throughput

0.437

High

881677

PEX3
Peroxisomal biogenesis factor 3

1

1

High-throughput

0.437

High

947479

RT35
Small ribosomal subunit protein mS35

1

1

High-throughput

0.437

High

1086486

NDUA5
NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 5

1

1

High-throughput

0.437

High

1222098

S15A3
Solute carrier family 15 member 3

1

1

High-throughput

0.437

High

1236486

SIR6
NAD-dependent protein deacylase sirtuin-6

1

4

High-throughput

0.437

High

1241400

SEN2
tRNA-splicing endonuclease subunit Sen2

1

1

High-throughput

0.437

High

1243134

FXL13
F-box and leucine-rich repeat protein 13

1

1

Small-scale

0.437

High

1289877

RT24
Small ribosomal subunit protein uS3m

1

1

High-throughput

0.437

High

1294381

RCC1L
RCC1-like G exchanging factor-like protein

1

1

High-throughput

0.437

High

1302830

IMP2L
Mitochondrial inner membrane protease subunit 2

1

2

High-throughput

0.437

High

1327246

DNJC4
DnaJ homolog subfamily C member 4

1

9

High-throughput

0.437

High

1327247

BIRC6
Baculoviral IAP repeat-containing protein 6

1

4

High-throughput

0.437

High

1327268

RT07
Small ribosomal subunit protein uS7m

1

5

High-throughput

0.437

High

1036887

SQSTM
Sequestosome-1

1

0

High-throughput

0.426

High

1327260

UVRAG
UV radiation resistance-associated gene protein

1

0

High-throughput

0.426

High

47691

A0AUL9
ATG2A protein

1

1

High-throughput

0.407

High

99679

F5H1C8
Solute carrier family 15 member 3

1

1

High-throughput

0.407

High

154568

ZN213
Zinc finger protein 213

1

1

High-throughput

0.407

High

1169901

PKHG7
Pleckstrin homology domain-containing family G member 7

1

2

High-throughput

0.407

High

1241610

MOT11
Monocarboxylate transporter 11

1

2

High-throughput

0.407

High

1327257

TRM1
tRNA

1

2

High-throughput

0.407

High

1327274

X6RFA8
Solute carrier family 25 member 28

1

6

High-throughput

0.407

High

1245775

CEP70
Centrosomal protein of 70 kDa

1

0

High-throughput

0.299

High

819671

NRIP1
Nuclear receptor-interacting protein 1

1

0

High-throughput

0.282

High

304451

REC8
Meiotic recombination protein REC8 homolog

1

0

High-throughput

0.279

Low

995932

PDE4D
3',5'-cyclic-AMP phosphodiesterase 4D

1

0

High-throughput

0.279

Low

1218626

FXRD2
FAD-dependent oxidoreductase domain-containing protein 2

1

0

High-throughput

0.279

Low

1239059

CO053
Putative uncharacterized protein encoded by LINC02694

1

0

High-throughput

0.279

Low

1327233

UN93B
Protein unc-93 homolog B1

1

0

High-throughput

0.279

Low

235302

OGA
Protein O-GlcNAcase

1

0

High-throughput

0.249

Low

641276

DNMT1
DNA

1

0

High-throughput

0.249

Low

1074992

TERF2
Telomeric repeat-binding factor 2

1

0

High-throughput

0.249

Low

1188837

PARPT
Protein mono-ADP-ribosyltransferase TIPARP

1

0

High-throughput

0.249

Low

1262390

MAIP1
m-AAA protease-interacting protein 1, mitochondrial

1

0

High-throughput

0.249

Low

1318563

NMES1
Normal mucosa of esophagus-specific gene 1 protein

1

0

High-throughput

0.249

Low

1327245

PLRKT
Plasminogen receptor

1

0

High-throughput

0.249

Low


Service provided by Combinatics, Japan

Last updated: 15 Jul 2024