Protein: P3C2A
Phosphatidylinositol 4-phosphate 3-kinase C2 domain-containing subunit alpha (PI3K-C2-alpha) (PtdIns-3-kinase C2 subunit alpha) (EC 2.7.1.137) (EC 2.7.1.153) (EC 2.7.1.154) (Phosphoinositide 3-kinase-C2-alpha)

Gene: P3C2A, PIK3C2A
Organism: Homo sapiens
Interactions: 173
UniProt ID: O00443

Gene Ontology (top 5):
GO:0005524 - ATP binding
GO:0005654 - nucleoplasm
GO:0005737 - cytoplasm
GO:0005802 - trans-Golgi network
GO:0005829 - cytosol

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

128887

HAVR2
Hepatitis A virus cellular receptor 2

2

2

High-throughput

0.726

High

128813

1433B
14-3-3 protein beta/alpha

5

20

High-throughput

0.722

High

128786

STABP
STAM-binding protein

4

1

High-throughput

0.697

High

128849

PICAL
Phosphatidylinositol-binding clathrin assembly protein

3

1

High-throughput

0.675

High

128800

CLCB
Clathrin light chain B

3

2

High-throughput

0.667

High

128882

CCNJL
Cyclin-J-like protein

3

2

High-throughput

0.667

High

128867

SNPC4
snRNA-activating protein complex subunit 4

1

0

High-throughput

0.656

High

128921

ANLN
Anillin

1

0

High-throughput

0.656

High

128930

PILRA
Paired immunoglobulin-like type 2 receptor alpha

1

0

High-throughput

0.656

High

128857

NADC
Nicotinate-nucleotide pyrophosphorylase [carboxylating]

3

0

High-throughput

0.638

High

128834

1433G
14-3-3 protein gamma

2

20

High-throughput

0.635

High

128836

1433E
14-3-3 protein epsilon

2

6

High-throughput

0.635

High

128838

1433Z
14-3-3 protein zeta/delta

2

20

High-throughput

0.635

High

128844

1433F
14-3-3 protein eta

2

20

High-throughput

0.635

High

128846

CDC16
Cell division cycle protein 16 homolog

2

2

High-throughput

0.628

High

128853

EPN4
Clathrin interactor 1

2

1

High-throughput

0.628

High

128897

STALP
AMSH-like protease

2

1

High-throughput

0.628

High

120195

RHOD
Rho-related GTP-binding protein RhoD

1

20

High-throughput

0.618

High

128776

STX6
Syntaxin-6

1

2

High-throughput

0.618

High

128782

RHBT1
Rho-related BTB domain-containing protein 1

1

20

High-throughput

0.618

High

128794

RAF1
RAF proto-oncogene serine/threonine-protein kinase

1

3

High-throughput

0.618

High

128803

RAC2
Ras-related C3 botulinum toxin substrate 2

1

20

High-throughput

0.618

High

128827

RND2
Rho-related GTP-binding protein RhoN

1

20

High-throughput

0.618

High

128832

CDC42
Cell division control protein 42 homolog

1

20

High-throughput

0.618

High

128833

RHOA
Transforming protein RhoA

1

20

High-throughput

0.618

High

128869

A16L1
Autophagy-related protein 16-1

1

11

High-throughput

0.618

High

128876

RHOU
Rho-related GTP-binding protein RhoU

1

20

High-throughput

0.618

High

128899

RHOV
Rho-related GTP-binding protein RhoV

1

20

High-throughput

0.618

High

128904

DNJC7
DnaJ homolog subfamily C member 7

1

5

High-throughput

0.618

High

128914

PKHA4
Pleckstrin homology domain-containing family A member 4

1

10

High-throughput

0.618

High

128919

RHOF
Rho-related GTP-binding protein RhoF

1

20

High-throughput

0.618

High

128920

MYO10
Unconventional myosin-X

1

3

Small-scale

0.618

High

128929

FBW1B
F-box/WD repeat-containing protein 11

1

6

High-throughput

0.618

High

47719

RBM47
RNA-binding protein 47

2

3

High-throughput

0.611

High

128799

CLCA
Clathrin light chain A

2

2

High-throughput

0.611

High

128913

MLP3A
Microtubule-associated proteins 1A/1B light chain 3A

2

2

Small-scale

0.611

High

128871

CNDH2
Condensin-2 complex subunit H2

2

0

High-throughput

0.602

High

128896

F136A
Protein FAM136A

2

0

High-throughput

0.602

High

128936

CRYL1
Lambda-crystallin homolog

2

0

High-throughput

0.602

High

128801

HSP7C
Heat shock cognate 71 kDa protein

2

1

High-throughput

0.584

High

128771

P3C2A
Phosphatidylinositol 4-phosphate 3-kinase C2 domain-containing subunit alpha

1

13

High-throughput

0.575

High

128872

PKHA7
Pleckstrin homology domain-containing family A member 7

1

10

High-throughput

0.575

High

128793

ESR1
Estrogen receptor

2

10

High-throughput

0.571

High

128824

PAXI
Paxillin

2

1

High-throughput

0.571

High

128810

1433T
14-3-3 protein theta

1

20

High-throughput

0.554

High

128864

AMOT
Angiomotin

1

10

High-throughput

0.541

High

128772

GAK
Cyclin-G-associated kinase

1

2

High-throughput

0.536

High

128773

SC16A
Protein transport protein Sec16A

1

1

High-throughput

0.536

High

128774

GP182
G-protein coupled receptor 182

1

20

High-throughput

0.536

High

128775

ACTN4
Alpha-actinin-4

1

3

High-throughput

0.536

High

128780

AUXI
Auxilin

1

1

High-throughput

0.536

High

128791

PGK1
Phosphoglycerate kinase 1

1

1

High-throughput

0.536

High

128807

FLNA
Filamin-A

1

2

High-throughput

0.536

High

128808

ROA2
Heterogeneous nuclear ribonucleoproteins A2/B1

1

1

High-throughput

0.536

High

128809

SYTC
Threonine--tRNA ligase 1, cytoplasmic

1

1

High-throughput

0.536

High

128815

ARRB2
Beta-arrestin-2

1

2

High-throughput

0.536

High

128818

MYH9
Myosin-9

1

5

High-throughput

0.536

High

128821

IQGA1
Ras GTPase-activating-like protein IQGAP1

1

2

High-throughput

0.536

High

128822

CAZA2
F-actin-capping protein subunit alpha-2

1

1

High-throughput

0.536

High

128823

CAPZB
F-actin-capping protein subunit beta

1

1

High-throughput

0.536

High

128825

ARRB1
Beta-arrestin-1

1

2

High-throughput

0.536

High

128835

PP1B
Serine/threonine-protein phosphatase PP1-beta catalytic subunit

1

3

High-throughput

0.536

High

128840

CLH1
Clathrin heavy chain 1

1

6

High-throughput

0.536

High

128842

FKBP4
Peptidyl-prolyl cis-trans isomerase FKBP4

1

7

High-throughput

0.536

High

128845

LG3BP
Galectin-3-binding protein

1

2

High-throughput

0.536

High

128847

TIF1B
Transcription intermediary factor 1-beta

1

4

High-throughput

0.536

High

128855

P2RY6
P2Y purinoceptor 6

1

20

High-throughput

0.536

High

128856

TEBP
Prostaglandin E synthase 3

1

3

High-throughput

0.536

High

128859

SC23A
Protein transport protein Sec23A

1

1

High-throughput

0.536

High

128860

OASL
2'-5'-oligoadenylate synthase-like protein

1

3

High-throughput

0.536

High

128862

DREB
Drebrin

1

4

High-throughput

0.536

High

128891

MY18A
Unconventional myosin-XVIIIa

1

8

High-throughput

0.536

High

128895

EFMT3
EEF1A lysine methyltransferase 3

1

2

High-throughput

0.536

High

128898

MYO19
Unconventional myosin-XIX

1

10

High-throughput

0.536

High

128900

TMM74
Transmembrane protein 74

1

2

High-throughput

0.536

High

128907

DUS16
Dual specificity protein phosphatase 16

1

3

High-throughput

0.536

High

128908

WNK3
Serine/threonine-protein kinase WNK3

1

4

High-throughput

0.536

High

128926

ANFY1
Rabankyrin-5

1

1

High-throughput

0.536

High

128927

LIMA1
LIM domain and actin-binding protein 1

1

3

High-throughput

0.536

High

128933

PA2G4
Proliferation-associated protein 2G4

1

3

High-throughput

0.536

High

128935

LRCH1
Leucine-rich repeat and calponin homology domain-containing protein 1

1

1

High-throughput

0.536

High

128938

STK24
Serine/threonine-protein kinase 24

1

9

High-throughput

0.536

High

128915

DUS21
Dual specificity protein phosphatase 21

1

3

High-throughput

0.515

High

128785

ATG7
Ubiquitin-like modifier-activating enzyme ATG7

1

0

High-throughput

0.513

High

128788

BAG2
BAG family molecular chaperone regulator 2

1

0

High-throughput

0.513

High

128789

AL1A1
Aldehyde dehydrogenase 1A1

1

0

High-throughput

0.513

High

128797

PROF1
Profilin-1

1

0

High-throughput

0.513

High

128804

NQO1
NAD(P)H dehydrogenase [quinone] 1

1

0

High-throughput

0.513

High

128806

CAN2
Calpain-2 catalytic subunit

1

0

High-throughput

0.513

High

128829

RPAB4
DNA-directed RNA polymerases I, II, and III subunit RPABC4

1

0

High-throughput

0.513

High

128839

TYB10
Thymosin beta-10

1

0

High-throughput

0.513

High

128865

EFMT2
EEF1A lysine methyltransferase 2

1

0

High-throughput

0.513

High

128873

LYPD4
Ly6/PLAUR domain-containing protein 4

1

0

High-throughput

0.513

High

128879

POGZ
Pogo transposable element with ZNF domain

1

0

High-throughput

0.513

High

128884

SYNPO
Synaptopodin

1

0

High-throughput

0.513

High

128889

YLAT2
Y+L amino acid transporter 2

1

0

High-throughput

0.513

High

128910

IF5A2
Eukaryotic translation initiation factor 5A-2

1

0

High-throughput

0.513

High

128911

CXL16
C-X-C motif chemokine 16

1

0

High-throughput

0.513

High

128918

PAAT
ATPase PAAT

1

0

High-throughput

0.513

High

128922

RPC2
DNA-directed RNA polymerase III subunit RPC2

1

0

High-throughput

0.513

High

128924

GTSE1
G2 and S phase-expressed protein 1

1

0

High-throughput

0.513

High

128937

BACE2
Beta-secretase 2

1

0

High-throughput

0.513

High

71027

HNRC2
Heterogeneous nuclear ribonucleoprotein C-like 2

1

1

High-throughput

0.489

High

128820

MAGA9
Melanoma-associated antigen 9

1

2

High-throughput

0.489

High

128902

MA7D2
MAP7 domain-containing protein 2

1

9

High-throughput

0.489

High

118815

GTPB1
GTP-binding protein 1

1

2

High-throughput

0.479

High

128777

PRKN
E3 ubiquitin-protein ligase parkin

1

7

High-throughput

0.479

High

128778

NUPR1
Nuclear protein 1

1

1

High-throughput

0.479

High

128779

DNJA2
DnaJ homolog subfamily A member 2

1

2

High-throughput

0.479

High

128781

NU155
Nuclear pore complex protein Nup155

1

1

High-throughput

0.479

High

128783

TRI37
E3 ubiquitin-protein ligase TRIM37

1

10

High-throughput

0.479

High

128784

KI20A
Kinesin-like protein KIF20A

1

9

High-throughput

0.479

High

128787

STAU1
Double-stranded RNA-binding protein Staufen homolog 1

1

3

High-throughput

0.479

High

128792

MYC
Myc proto-oncogene protein

1

4

High-throughput

0.479

High

128796

NTRK1
High affinity nerve growth factor receptor

1

17

High-throughput

0.479

High

128798

VIME
Vimentin

1

3

High-throughput

0.479

High

128802

TRI27
Zinc finger protein RFP

1

1

Small-scale

0.479

High

128805

RFA2
Replication protein A 32 kDa subunit

1

4

High-throughput

0.479

High

128811

RFA1
Replication protein A 70 kDa DNA-binding subunit

1

3

High-throughput

0.479

High

128814

1433S
14-3-3 protein sigma

1

20

High-throughput

0.479

High

128817

RFA3
Replication protein A 14 kDa subunit

1

3

High-throughput

0.479

High

128819

MLH1
DNA mismatch repair protein Mlh1

1

3

High-throughput

0.479

High

128828

AK1C2
Aldo-keto reductase family 1 member C2

1

2

High-throughput

0.479

High

128830

PMS1
PMS1 protein homolog 1

1

3

High-throughput

0.479

High

128831

PMS2
Mismatch repair endonuclease PMS2

1

3

High-throughput

0.479

High

128837

AP2B1
AP-2 complex subunit beta

1

3

High-throughput

0.479

High

128848

FKBP5
Peptidyl-prolyl cis-trans isomerase FKBP5

1

7

High-throughput

0.479

High

128851

EIF3A
Eukaryotic translation initiation factor 3 subunit A

1

14

High-throughput

0.479

High

128852

UBP2L
Ubiquitin-associated protein 2-like

1

2

High-throughput

0.479

High

128854

KIF14
Kinesin-like protein KIF14

1

7

High-throughput

0.479

High

128870

LTOR1
Ragulator complex protein LAMTOR1

1

5

High-throughput

0.479

High

128874

SYNE3
Nesprin-3

1

11

High-throughput

0.479

High

128875

TRI67
Tripartite motif-containing protein 67

1

8

High-throughput

0.479

High

128877

ATG9A
Autophagy-related protein 9A

1

1

High-throughput

0.479

High

128878

PARPT
Protein mono-ADP-ribosyltransferase TIPARP

1

2

High-throughput

0.479

High

128883

RHG18
Rho GTPase-activating protein 18

1

1

High-throughput

0.479

High

128888

SMAP2
Stromal membrane-associated protein 2

1

2

High-throughput

0.479

High

128892

AKAP1
A-kinase anchor protein 1, mitochondrial

1

1

High-throughput

0.479

High

128893

ESR2
Estrogen receptor beta

1

10

High-throughput

0.479

High

128894

CSN5
COP9 signalosome complex subunit 5

1

3

High-throughput

0.479

High

128905

LZTS2
Leucine zipper putative tumor suppressor 2

1

10

High-throughput

0.479

High

128912

PTN23
Tyrosine-protein phosphatase non-receptor type 23

1

2

Small-scale

0.479

High

128916

EGLN3
Prolyl hydroxylase EGLN3

1

2

High-throughput

0.479

High

128928

ANC2
Anaphase-promoting complex subunit 2

1

5

High-throughput

0.479

High

128931

MYO6
Unconventional myosin-VI

1

7

Small-scale

0.479

High

128932

MAGD2
Melanoma-associated antigen D2

1

2

High-throughput

0.479

High

128934

NINL
Ninein-like protein

1

7

High-throughput

0.479

High

128812

TKT
Transketolase

1

0

High-throughput

0.458

High

128866

SMAG2
Protein Smaug homolog 2

1

0

High-throughput

0.458

High

128880

YTHD3
YTH domain-containing family protein 3

1

0

High-throughput

0.458

High

128881

DYR2
Dihydrofolate reductase 2, mitochondrial

1

0

High-throughput

0.458

High

128886

NUP35
Nucleoporin NUP35

1

0

High-throughput

0.458

High

128890

CNOT9
CCR4-NOT transcription complex subunit 9

1

0

High-throughput

0.458

High

128903

RMD3
Regulator of microtubule dynamics protein 3

1

0

High-throughput

0.458

High

128906

LGR4
Leucine-rich repeat-containing G-protein coupled receptor 4

1

0

High-throughput

0.458

High

128917

TDRD3
Tudor domain-containing protein 3

1

0

High-throughput

0.458

High

128861

EREP1
Endosomal transmembrane epsin interactor 1

1

1

Small-scale

0.457

High

128790

EGFR
Epidermal growth factor receptor

1

18

Small-scale

0.445

High

128795

ERBB2
Receptor tyrosine-protein kinase erbB-2

1

15

Small-scale

0.445

High

128816

BMI1
Polycomb complex protein BMI-1

1

1

High-throughput

0.445

High

128843

AK1C1
Aldo-keto reductase family 1 member C1

1

2

High-throughput

0.445

High

128850

DYR1A
Dual specificity tyrosine-phosphorylation-regulated kinase 1A

1

3

High-throughput

0.445

High

128909

ZDHC5
Palmitoyltransferase ZDHHC5

1

5

High-throughput

0.445

High

128826

TSP3
Thrombospondin-3

1

1

High-throughput

0.437

High

128858

TOM20
Mitochondrial import receptor subunit TOM20 homolog

1

1

High-throughput

0.437

High

128841

OCRL
Inositol polyphosphate 5-phosphatase OCRL

1

0

High-throughput

0.426

High

128925

PP4RL
Putative serine/threonine-protein phosphatase 4 regulatory subunit 1-like

1

3

High-throughput

0.407

High

128868

CF141
Uncharacterized protein C6orf141

2

0

High-throughput

0.328

High

128863

CF184
Cilia- and flagella-associated protein 184

1

0

High-throughput

0.279

Low

128901

ARX
Homeobox protein ARX

1

0

High-throughput

0.279

Low

128885

S2541
Mitochondrial carrier protein SCaMC-3L

1

0

High-throughput

0.249

Low

128923

F120C
Constitutive coactivator of PPAR-gamma-like protein 2

1

0

High-throughput

0.249

Low


Service provided by Combinatics, Japan

Last updated: 15 Jul 2024