Protein: ACOT8
Acyl-coenzyme A thioesterase 8 (Acyl-CoA thioesterase 8) (EC 3.1.2.1) (EC 3.1.2.11) (EC 3.1.2.2) (EC 3.1.2.3) (EC 3.1.2.5) (Choloyl-coenzyme A thioesterase) (EC 3.1.2.27) (HIV-Nef-associated acyl-CoA thioesterase) (Peroxisomal acyl-CoA thioesterase 2) (PTE-2) (Peroxisomal acyl-coenzyme A thioester hydrolase 1) (PTE-1) (Peroxisomal long-chain acyl-CoA thioesterase 1) (Thioesterase II) (hACTE-III) (hACTEIII) (hTE)

Gene: ACOT8
Organism: Homo sapiens
Interactions: 51
UniProt ID: O14734

Gene Ontology (top 5):
GO:0003986 - acetyl-CoA hydrolase activity
GO:0004778 - succinyl-CoA hydrolase activity
GO:0005782 - peroxisomal matrix
GO:0005829 - cytosol
GO:0006637 - acyl-CoA metabolic process

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

153217

PML
Protein PML

3

1

High-throughput

0.667

High

153222

PEX5
Peroxisomal targeting signal 1 receptor

4

0

Small-scale

0.663

High

153225

REL
Proto-oncogene c-Rel

3

0

High-throughput

0.646

High

153216

PTN3
Tyrosine-protein phosphatase non-receptor type 3

2

0

High-throughput

0.585

High

153206

ESR1
Estrogen receptor

2

1

High-throughput

0.571

High

153212

CFTR
Cystic fibrosis transmembrane conductance regulator

1

0

High-throughput

0.518

High

153218

MK04
Mitogen-activated protein kinase 4

1

0

High-throughput

0.513

High

153233

HSC20
Iron-sulfur cluster co-chaperone protein HscB

1

0

High-throughput

0.513

High

153236

CDC26
Anaphase-promoting complex subunit CDC26

1

0

High-throughput

0.513

High

153248

FBX7
F-box only protein 7

1

0

High-throughput

0.480

High

153208

GCR
Glucocorticoid receptor

1

1

High-throughput

0.479

High

153244

PRD16
Histone-lysine N-methyltransferase PRDM16

1

0

High-throughput

0.460

High

116525

ADAS
Alkyldihydroxyacetonephosphate synthase, peroxisomal

1

0

High-throughput

0.458

High

148131

CTRO
Citron Rho-interacting kinase

1

0

High-throughput

0.458

High

153207

CATA
Catalase

1

0

High-throughput

0.458

High

153209

ISG15
Ubiquitin-like protein ISG15

1

0

High-throughput

0.458

High

153211

TAU
Microtubule-associated protein tau

1

0

High-throughput

0.458

High

153221

CCNF
Cyclin-F

1

0

High-throughput

0.458

High

153223

UBE2H
Ubiquitin-conjugating enzyme E2 H

1

0

High-throughput

0.458

High

153226

CUL3
Cullin-3

1

0

High-throughput

0.458

High

153227

CL16A
Protein CLEC16A

1

0

High-throughput

0.458

High

153230

TBA1A
Tubulin alpha-1A chain

1

0

High-throughput

0.458

High

153235

MTMRE
Myotubularin-related protein 14

1

0

High-throughput

0.458

High

153239

OTUL
Ubiquitin thioesterase otulin

1

0

Small-scale

0.458

High

153245

NMRL1
NmrA-like family domain-containing protein 1

1

0

High-throughput

0.458

High

153246

ZRAN1
Ubiquitin thioesterase ZRANB1

1

0

High-throughput

0.458

High

153202

BRD1
Bromodomain-containing protein 1

1

1

High-throughput

0.437

High

153214

TAF1
Transcription initiation factor TFIID subunit 1

1

3

High-throughput

0.437

High

153237

TP4A1
Protein tyrosine phosphatase type IVA 1

1

1

High-throughput

0.437

High

153241

RING2
E3 ubiquitin-protein ligase RING2

1

1

High-throughput

0.437

High

153242

BRD8
Bromodomain-containing protein 8

1

2

High-throughput

0.437

High

153234

KLH23
Kelch-like protein 23

3

0

High-throughput

0.347

High

153231

P4HA3
Prolyl 4-hydroxylase subunit alpha-3

2

0

High-throughput

0.316

High

153203

MYC
Myc proto-oncogene protein

1

0

High-throughput

0.279

Low

153210

ODPA
Pyruvate dehydrogenase E1 component subunit alpha, somatic form, mitochondrial

1

0

High-throughput

0.279

Low

153228

VSTM1
V-set and transmembrane domain-containing protein 1

1

0

High-throughput

0.279

Low

153238

SNX21
Sorting nexin-21

1

0

High-throughput

0.279

Low

153247

MAST1
Microtubule-associated serine/threonine-protein kinase 1

1

0

High-throughput

0.279

Low

153240

COA7
Cytochrome c oxidase assembly factor 7

1

0

High-throughput

0.269

Low

47721

RBM47
RNA-binding protein 47

1

0

High-throughput

0.249

Low

153201

TRI66
Tripartite motif-containing protein 66

1

0

High-throughput

0.249

Low

153204

INS
Insulin [Cleaved into: Insulin B chain; Insulin A chain]

1

0

High-throughput

0.249

Low

153213

AMPN
Aminopeptidase N

1

0

High-throughput

0.249

Low

153215

SP100
Nuclear autoantigen Sp-100

1

0

High-throughput

0.249

Low

153219

PHB1
Prohibitin 1

1

0

High-throughput

0.249

Low

153220

BRCA1
Breast cancer type 1 susceptibility protein

1

0

High-throughput

0.249

Low

153224

VIGLN
Vigilin

1

0

High-throughput

0.249

Low

153229

TRI67
Tripartite motif-containing protein 67

1

0

High-throughput

0.249

Low

153232

TM11B
Transmembrane protease serine 11B

1

0

High-throughput

0.249

Low

153243

PKHA4
Pleckstrin homology domain-containing family A member 4

1

0

High-throughput

0.249

Low

153205

IGHA1
Immunoglobulin heavy constant alpha 1

1

0

High-throughput

0.232

Low


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Last updated: 15 Jul 2024