Protein: DGKZ
Diacylglycerol kinase zeta (DAG kinase zeta) (EC 2.7.1.107) (EC 2.7.1.93) (Diglyceride kinase zeta) (DGK-zeta)

Gene: DGKZ
Organism: Homo sapiens
Interactions: 80
UniProt ID: Q13574

Gene Ontology (top 5):
GO:0001727 - lipid kinase activity
GO:0004143 - ATP-dependent diacylglycerol kinase activity
GO:0005524 - ATP binding
GO:0005634 - nucleus
GO:0005737 - cytoplasm

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

386691

P53
Cellular tumor antigen p53

1

2

Small-scale

0.724

High

586733

CSK22
Casein kinase II subunit alpha'

1

4

High-throughput

0.691

High

934152

CSK21
Casein kinase II subunit alpha

1

5

High-throughput

0.691

High

1039996

DDX51
ATP-dependent RNA helicase DDX51

1

1

High-throughput

0.691

High

310028

GRP1
RAS guanyl-releasing protein 1

1

4

Small-scale

0.665

High

349298

RASH
GTPase HRas

1

13

Small-scale

0.665

High

1039989

MK06
Mitogen-activated protein kinase 6

1

7

High-throughput

0.656

High

1039994

ASCC3
Activating signal cointegrator 1 complex subunit 3

1

0

High-throughput

0.656

High

1040005

DDX27
Probable ATP-dependent RNA helicase DDX27

1

0

High-throughput

0.656

High

1033829

SNTA1
Alpha-1-syntrophin

1

14

Small-scale

0.647

High

1033865

SNTB2
Beta-2-syntrophin

1

16

Small-scale

0.647

High

1039984

SNTB1
Beta-1-syntrophin

1

15

Small-scale

0.647

High

962560

ECT2L
Epithelial cell-transforming sequence 2 oncogene-like

1

6

High-throughput

0.618

High

374192

RAF1
RAF proto-oncogene serine/threonine-protein kinase

1

6

High-throughput

0.618

High

857118

CAZA1
F-actin-capping protein subunit alpha-1

1

2

High-throughput

0.618

High

600567

EPHA1
Ephrin type-A receptor 1

1

3

High-throughput

0.590

High

581003

PLCG1
1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-1

1

0

Small-scale

0.586

High

1040006

SNX27
Sorting nexin-27

2

4

Small-scale

0.584

High

369554

ESR1
Estrogen receptor

2

4

High-throughput

0.571

High

414274

RB
Retinoblastoma-associated protein

1

5

Small-scale

0.546

High

787228

PK3CA
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform

1

0

Small-scale

0.537

High

49245

FEZF1
Fez family zinc finger protein 1

1

2

High-throughput

0.536

High

470375

H2A1
Histone H2A type 1

1

1

High-throughput

0.536

High

559091

H15
Histone H1.5

1

6

High-throughput

0.536

High

559694

H12
Histone H1.2

1

6

High-throughput

0.536

High

685941

ARRB2
Beta-arrestin-2

1

5

High-throughput

0.536

High

827196

ARRB1
Beta-arrestin-1

1

5

High-throughput

0.536

High

876779

NP1L1
Nucleosome assembly protein 1-like 1

1

2

High-throughput

0.536

High

1039985

RRP5
Protein RRP5 homolog

1

1

High-throughput

0.536

High

1039987

TEBP
Prostaglandin E synthase 3

1

1

High-throughput

0.536

High

1039988

ZKSC8
Zinc finger protein with KRAB and SCAN domains 8

1

1

High-throughput

0.536

High

1039993

KBTB6
Kelch repeat and BTB domain-containing protein 6

1

2

High-throughput

0.536

High

1039999

NOC3L
Nucleolar complex protein 3 homolog

1

1

High-throughput

0.536

High

1040000

HNRLL
Heterogeneous nuclear ribonucleoprotein L-like

1

1

High-throughput

0.536

High

1040001

KBTB7
Kelch repeat and BTB domain-containing protein 7

1

1

High-throughput

0.536

High

1040008

NP1L4
Nucleosome assembly protein 1-like 4

1

2

High-throughput

0.536

High

1040009

PI51A
Phosphatidylinositol 4-phosphate 5-kinase type-1 alpha

1

2

High-throughput

0.536

High

1040010

UBE2O
(E3-independent) E2 ubiquitin-conjugating enzyme

1

1

High-throughput

0.536

High

1040014

HM20A
High mobility group protein 20A

1

2

High-throughput

0.536

High

997112

RBL2
Retinoblastoma-like protein 2

1

5

Small-scale

0.534

High

600018

SAT1
Diamine acetyltransferase 1

1

0

High-throughput

0.518

High

852911

HNRPM
Heterogeneous nuclear ribonucleoprotein M

1

2

High-throughput

0.515

High

179174

COPT1
High affinity copper uptake protein 1

1

0

High-throughput

0.513

High

196093

RRP8
Ribosomal RNA-processing protein 8

1

0

High-throughput

0.513

High

230352

ZC3H1
Zinc finger C3H1 domain-containing protein

1

0

High-throughput

0.513

High

364884

FRIL
Ferritin light chain

1

0

High-throughput

0.513

High

826407

FNTA
Protein farnesyltransferase/geranylgeranyltransferase type-1 subunit alpha

1

0

High-throughput

0.513

High

826453

FNTB
Protein farnesyltransferase subunit beta

1

0

High-throughput

0.513

High

931625

CSK2B
Casein kinase II subunit beta

1

0

High-throughput

0.513

High

957830

EFNB1
Ephrin-B1

1

0

High-throughput

0.513

High

977230

CEBPZ
CCAAT/enhancer-binding protein zeta

1

0

High-throughput

0.513

High

1039986

BMS1
Ribosome biogenesis protein BMS1 homolog

1

0

High-throughput

0.513

High

1039992

TRM1L
TRMT1-like protein

1

0

High-throughput

0.513

High

1039998

LRC15
Leucine-rich repeat-containing protein 15

1

0

High-throughput

0.513

High

1040004

ARK2N
Protein ARK2N

1

0

High-throughput

0.513

High

1040011

ASCC2
Activating signal cointegrator 1 complex subunit 2

1

0

High-throughput

0.513

High

1040013

CBX8
Chromobox protein homolog 8

1

0

High-throughput

0.513

High

1040017

ZN629
Zinc finger protein 629

1

0

High-throughput

0.513

High

1040019

NOC2L
Nucleolar complex protein 2 homolog

1

0

High-throughput

0.513

High

1018928

COX10
Protoheme IX farnesyltransferase, mitochondrial

1

0

High-throughput

0.493

High

1040016

RBM28
RNA-binding protein 28

1

1

High-throughput

0.489

High

660133

RBL1
Retinoblastoma-like protein 1

1

5

Small-scale

0.488

High

640243

PTN3
Tyrosine-protein phosphatase non-receptor type 3

1

4

High-throughput

0.479

High

771954

VHL
von Hippel-Lindau disease tumor suppressor

1

1

Small-scale

0.479

High

1040002

ESR2
Estrogen receptor beta

1

4

High-throughput

0.479

High

1040015

PAR6A
Partitioning defective 6 homolog alpha

1

10

Small-scale

0.479

High

1040018

ZRAN1
Ubiquitin thioesterase ZRANB1

1

4

High-throughput

0.479

High

162718

XPO1
Exportin-1

1

0

High-throughput

0.458

High

890651

PTEN
Phosphatidylinositol 3,4,5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase PTEN

1

0

Small-scale

0.458

High

1040003

RL36L
Ribosomal protein eL42-like

1

0

High-throughput

0.458

High

56618

PIPSL
Putative PIP5K1A and PSMD4-like protein

1

1

High-throughput

0.445

High

230047

NPA1P
Nucleolar pre-ribosomal-associated protein 1

1

0

High-throughput

0.279

Low

1039991

NOL8
Nucleolar protein 8

1

0

High-throughput

0.279

Low

1039995

FNBP4
Formin-binding protein 4

1

0

High-throughput

0.279

Low

1039997

WDR36
WD repeat-containing protein 36

1

0

High-throughput

0.279

Low

1040007

TEFM
Transcription elongation factor, mitochondrial

1

0

High-throughput

0.279

Low

1040012

NOL6
Nucleolar protein 6

1

0

High-throughput

0.279

Low

1039990

GL1AD
DNA-directed RNA polymerase II subunit GRINL1A, isoforms 4/5

1

0

High-throughput

0.251

Low

352097

INS
Insulin [Cleaved into: Insulin B chain; Insulin A chain]

1

0

High-throughput

0.249

Low

375738

GBA1
Lysosomal acid glucosylceramidase

1

0

Small-scale

0.249

Low


Service provided by Combinatics, Japan

Last updated: 15 Jul 2024