Protein: IL7RA
Interleukin-7 receptor subunit alpha (IL-7 receptor subunit alpha) (IL-7R subunit alpha) (IL-7R-alpha) (IL-7RA) (CDw127) (CD antigen CD127)

Gene: IL7RA, IL7R
Organism: Homo sapiens
Interactions: 149
UniProt ID: P16871

Gene Ontology (top 5):
GO:0000018 - regulation of DNA recombination
GO:0000902 - cell morphogenesis
GO:0001782 - B cell homeostasis
GO:0001913 - T cell mediated cytotoxicity
GO:0001915 - negative regulation of T cell mediated cytotoxicity

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

526539

IL7
Interleukin-7

4

0

Small-scale

0.860

High

562536

JAK3
Tyrosine-protein kinase JAK3

2

3

Small-scale

0.754

High

562584

CISH
Cytokine-inducible SH2-containing protein

2

4

Small-scale

0.754

High

562563

EPHA7
Ephrin type-A receptor 7

1

1

High-throughput

0.691

High

499227

KIT
Mast/stem cell growth factor receptor Kit

1

0

Small-scale

0.687

High

562531

KPCI
Protein kinase C iota type

1

0

High-throughput

0.656

High

562566

LAMA3
Laminin subunit alpha-3

1

0

High-throughput

0.656

High

562523

IL2RG
Cytokine receptor common subunit gamma

3

2

Small-scale

0.640

High

411991

FYN
Tyrosine-protein kinase Fyn

1

0

Small-scale

0.631

High

562570

CD302
CD302 antigen

1

0

High-throughput

0.630

High

146591

SOCS2
Suppressor of cytokine signaling 2

1

4

Small-scale

0.618

High

181790

SOCS1
Suppressor of cytokine signaling 1

1

5

Small-scale

0.618

High

562504

NFKB1
Nuclear factor NF-kappa-B p105 subunit

1

1

Small-scale

0.618

High

562506

JAK1
Tyrosine-protein kinase JAK1

1

3

High-throughput

0.618

High

562510

MK03
Mitogen-activated protein kinase 3

1

1

High-throughput

0.618

High

562515

MK01
Mitogen-activated protein kinase 1

1

1

High-throughput

0.618

High

562528

STAT3
Signal transducer and activator of transcription 3

1

2

High-throughput

0.618

High

562532

STAT1
Signal transducer and activator of transcription 1-alpha/beta

1

2

High-throughput

0.618

High

562533

STA5A
Signal transducer and activator of transcription 5A

1

2

High-throughput

0.618

High

562542

MTPN
Myotrophin

1

1

High-throughput

0.618

High

562545

GRB2
Growth factor receptor-bound protein 2

1

1

High-throughput

0.618

High

562561

FAK2
Protein-tyrosine kinase 2-beta

1

2

Small-scale

0.618

High

533190

PLSL
Plastin-2

1

0

High-throughput

0.586

High

562505

CBL
E3 ubiquitin-protein ligase CBL

1

0

Small-scale

0.586

High

562513

P85A
Phosphatidylinositol 3-kinase regulatory subunit alpha

1

0

Small-scale

0.586

High

562527

TAGL2
Transgelin-2

1

0

High-throughput

0.586

High

562564

MARE1
Microtubule-associated protein RP/EB family member 1

1

0

High-throughput

0.586

High

309205

APOL3
Apolipoprotein L3

2

0

High-throughput

0.580

High

515694

CD20
B-lymphocyte antigen CD20

2

0

High-throughput

0.580

High

562522

SDC4
Syndecan-4

2

0

High-throughput

0.580

High

562557

MALL
MAL-like protein

2

0

High-throughput

0.580

High

562568

ATRAP
Type-1 angiotensin II receptor-associated protein

2

0

High-throughput

0.580

High

562573

VANG1
Vang-like protein 1

1

1

High-throughput

0.536

High

562574

PMGT1
Protein O-linked-mannose beta-1,2-N-acetylglucosaminyltransferase 1

1

1

High-throughput

0.536

High

562587

GMEB2
Glucocorticoid modulatory element-binding protein 2

1

1

High-throughput

0.536

High

562589

VANG2
Vang-like protein 2

1

1

High-throughput

0.536

High

562593

GMEB1
Glucocorticoid modulatory element-binding protein 1

1

1

High-throughput

0.536

High

562553

TF65
Transcription factor p65

1

1

Small-scale

0.534

High

117252

PDLI1
PDZ and LIM domain protein 1

1

0

High-throughput

0.517

High

562575

FAM3C
Protein FAM3C

1

1

High-throughput

0.515

High

237935

EXOC3
Exocyst complex component 3

1

0

High-throughput

0.513

High

447015

FGF2
Fibroblast growth factor 2

1

0

High-throughput

0.513

High

562541

ECHB
Trifunctional enzyme subunit beta, mitochondrial

1

0

High-throughput

0.513

High

562552

AMPD2
AMP deaminase 2

1

0

High-throughput

0.513

High

562555

TF3C1
General transcription factor 3C polypeptide 1

1

0

High-throughput

0.513

High

562558

SQSTM
Sequestosome-1

1

0

High-throughput

0.513

High

562571

TM192
Transmembrane protein 192

1

0

High-throughput

0.513

High

562592

TF3C3
General transcription factor 3C polypeptide 3

1

0

High-throughput

0.513

High

417907

NPM
Nucleophosmin

1

0

High-throughput

0.493

High

306754

VAMP5
Vesicle-associated membrane protein 5

1

0

High-throughput

0.493

High

562511

VATL
V-type proton ATPase 16 kDa proteolipid subunit c

1

0

High-throughput

0.493

High

562529

ECHA
Trifunctional enzyme subunit alpha, mitochondrial

1

1

High-throughput

0.489

High

150288

CCS
Copper chaperone for superoxide dismutase

1

1

High-throughput

0.479

High

336350

SODC
Superoxide dismutase [Cu-Zn]

1

1

High-throughput

0.479

High

381114

TBB4A
Tubulin beta-4A chain

1

4

High-throughput

0.479

High

385836

CPNS1
Calpain small subunit 1

1

1

High-throughput

0.479

High

409445

MYL1
Myosin light chain 1/3, skeletal muscle isoform

1

2

High-throughput

0.479

High

417141

ENOA
Alpha-enolase

1

1

High-throughput

0.479

High

418868

TPM3
Tropomyosin alpha-3 chain

1

1

High-throughput

0.479

High

423135

PDIA1
Protein disulfide-isomerase

1

2

High-throughput

0.479

High

428005

TBB5
Tubulin beta chain

1

4

High-throughput

0.479

High

441661

MYL3
Myosin light chain 3

1

2

High-throughput

0.479

High

447652

ENOG
Gamma-enolase

1

1

High-throughput

0.479

High

449178

LEG1
Galectin-1

1

1

High-throughput

0.479

High

495454

THIO
Thioredoxin

1

1

High-throughput

0.479

High

501649

BIP
Endoplasmic reticulum chaperone BiP

1

3

High-throughput

0.479

High

503384

HSP7C
Heat shock cognate 71 kDa protein

1

2

High-throughput

0.479

High

546919

EZRI
Ezrin

1

1

High-throughput

0.479

High

562502

HSP76
Heat shock 70 kDa protein 6

1

2

High-throughput

0.479

High

562507

COF1
Cofilin-1

1

1

High-throughput

0.479

High

562508

MOES
Moesin

1

1

High-throughput

0.479

High

562516

ERP29
Endoplasmic reticulum resident protein 29

1

3

High-throughput

0.479

High

562517

PRDX6
Peroxiredoxin-6

1

2

High-throughput

0.479

High

562518

PRDX3
Thioredoxin-dependent peroxide reductase, mitochondrial

1

2

High-throughput

0.479

High

562521

SORCN
Sorcin

1

1

High-throughput

0.479

High

562524

1433B
14-3-3 protein beta/alpha

1

1

High-throughput

0.479

High

562525

PRDX2
Peroxiredoxin-2

1

2

High-throughput

0.479

High

562526

HS71L
Heat shock 70 kDa protein 1-like

1

2

High-throughput

0.479

High

562543

MYL6
Myosin light polypeptide 6

1

2

High-throughput

0.479

High

562544

ACTB
Actin, cytoplasmic 1

1

1

High-throughput

0.479

High

562546

1433Z
14-3-3 protein zeta/delta

1

1

High-throughput

0.479

High

562547

ACTG
Actin, cytoplasmic 2

1

1

High-throughput

0.479

High

562548

TPM4
Tropomyosin alpha-4 chain

1

1

High-throughput

0.479

High

562550

TBA4A
Tubulin alpha-4A chain

1

6

High-throughput

0.479

High

562551

TBB4B
Tubulin beta-4B chain

1

4

High-throughput

0.479

High

562554

PSME1
Proteasome activator complex subunit 1

1

1

High-throughput

0.479

High

562556

ECH1
Delta(3,5)-Delta(2,4)-dienoyl-CoA isomerase, mitochondrial

1

1

High-throughput

0.479

High

562560

COTL1
Coactosin-like protein

1

1

High-throughput

0.479

High

562562

PDIA6
Protein disulfide-isomerase A6

1

2

High-throughput

0.479

High

562569

TBA1A
Tubulin alpha-1A chain

1

6

High-throughput

0.479

High

562586

DBNL
Drebrin-like protein

1

1

High-throughput

0.479

High

562588

PSME2
Proteasome activator complex subunit 2

1

1

High-throughput

0.479

High

224295

RAD21
Double-strand-break repair protein rad21 homolog

1

0

High-throughput

0.460

High

124567

CLIC1
Chloride intracellular channel protein 1

1

0

High-throughput

0.458

High

181295

ARPC5
Actin-related protein 2/3 complex subunit 5

1

0

High-throughput

0.458

High

261074

SH3L1
Adapter SH3BGRL

1

0

High-throughput

0.458

High

336922

F13A
Coagulation factor XIII A chain

1

0

High-throughput

0.458

High

361309

APOA1
Apolipoprotein A-I

1

0

High-throughput

0.458

High

361973

FIBG
Fibrinogen gamma chain

1

0

High-throughput

0.458

High

363561

TTHY
Transthyretin

1

0

High-throughput

0.458

High

363711

ALBU
Albumin

1

0

High-throughput

0.458

High

364038

CXCL7
Platelet basic protein

1

0

High-throughput

0.458

High

364519

TRFE
Serotransferrin

1

0

High-throughput

0.458

High

378430

SODM
Superoxide dismutase [Mn], mitochondrial

1

0

High-throughput

0.458

High

381786

G3P
Glyceraldehyde-3-phosphate dehydrogenase

1

0

High-throughput

0.458

High

388209

HSPB1
Heat shock protein beta-1

1

0

High-throughput

0.458

High

413821

GELS
Gelsolin

1

0

High-throughput

0.458

High

415193

ATPB
ATP synthase subunit beta, mitochondrial

1

0

High-throughput

0.458

High

421964

LDHB
L-lactate dehydrogenase B chain

1

0

High-throughput

0.458

High

430041

PROF1
Profilin-1

1

0

High-throughput

0.458

High

430442

APT
Adenine phosphoribosyltransferase

1

0

High-throughput

0.458

High

439929

ITA2B
Integrin alpha-IIb

1

0

High-throughput

0.458

High

440935

PLEK
Pleckstrin

1

0

High-throughput

0.458

High

445274

RSSA
Small ribosomal subunit protein uS2

1

0

High-throughput

0.458

High

448284

GSTP1
Glutathione S-transferase P

1

0

High-throughput

0.458

High

499513

CH60
60 kDa heat shock protein, mitochondrial

1

0

High-throughput

0.458

High

562503

VINC
Vinculin

1

0

High-throughput

0.458

High

562509

S10A4
Protein S100-A4

1

0

High-throughput

0.458

High

562512

CALR
Calreticulin

1

0

High-throughput

0.458

High

562514

PSA5
Proteasome subunit alpha type-5

1

0

High-throughput

0.458

High

562519

PEBP1
Phosphatidylethanolamine-binding protein 1

1

0

High-throughput

0.458

High

562530

BCL6
B-cell lymphoma 6 protein

1

0

Small-scale

0.458

High

562534

CAPZB
F-actin-capping protein subunit beta

1

0

High-throughput

0.458

High

562535

TCPE
T-complex protein 1 subunit epsilon

1

0

High-throughput

0.458

High

562537

GDIR1
Rho GDP-dissociation inhibitor 1

1

0

High-throughput

0.458

High

562538

CAZA1
F-actin-capping protein subunit alpha-1

1

0

High-throughput

0.458

High

562539

SNAA
Alpha-soluble NSF attachment protein

1

0

High-throughput

0.458

High

562540

TERA
Transitional endoplasmic reticulum ATPase

1

0

High-throughput

0.458

High

562565

ZYX
Zyxin

1

0

High-throughput

0.458

High

562577

PARK7
Parkinson disease protein 7

1

0

High-throughput

0.458

High

562590

NSF1C
NSFL1 cofactor p47

1

0

High-throughput

0.458

High

313679

BRI3
Membrane protein BRI3

1

0

Small-scale

0.438

High

562520

PDIA3
Protein disulfide-isomerase A3

1

2

High-throughput

0.437

High

562549

TBA1B
Tubulin alpha-1B chain

1

6

High-throughput

0.437

High

562559

TBB2A
Tubulin beta-2A chain

1

4

High-throughput

0.437

High

562567

LEGL
Galectin-related protein

1

1

High-throughput

0.437

High

562578

TBA1C
Tubulin alpha-1C chain

1

6

High-throughput

0.437

High

562580

TBB6
Tubulin beta-6 chain

1

4

High-throughput

0.437

High

562582

TBB1
Tubulin beta-1 chain

1

6

High-throughput

0.437

High

562585

TBA8
Tubulin alpha-8 chain

1

6

High-throughput

0.437

High

562591

COF2
Cofilin-2

1

1

High-throughput

0.437

High

49301

T120B
Transmembrane protein 120B

2

0

High-throughput

0.316

High

68132

F1712
Protein FAM171A2

1

0

High-throughput

0.279

Low

470255

H2A1
Histone H2A type 1

1

0

High-throughput

0.279

Low

562572

MFSD8
Major facilitator superfamily domain-containing protein 8

1

0

High-throughput

0.279

Low

562576

MITOK
Mitochondrial potassium channel

1

0

High-throughput

0.279

Low

562579

CQ080
Mitochondrial nucleoid-associated protein 1

1

0

High-throughput

0.279

Low

562583

PRD10
PR domain zinc finger protein 10

1

0

High-throughput

0.279

Low

562581

TMM60
Transmembrane protein 60

1

0

High-throughput

0.268

Low


Service provided by Combinatics, Japan

Last updated: 15 Jul 2024