Protein: CTLA4
Cytotoxic T-lymphocyte protein 4 (Cytotoxic T-lymphocyte-associated antigen 4) (CTLA-4) (CD antigen CD152)

Gene: CTLA4
Organism: Homo sapiens
Interactions: 109
UniProt ID: P16410

Gene Ontology (top 5):
GO:0002250 - adaptive immune response
GO:0005794 - Golgi apparatus
GO:0005886 - plasma membrane
GO:0006955 - immune response
GO:0006974 - DNA damage response

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

560040

CD80
T-lymphocyte activation antigen CD80

4

7

Small-scale

0.906

High

560044

CD86
T-lymphocyte activation antigen CD86

2

7

Small-scale

0.817

High

499226

KIT
Mast/stem cell growth factor receptor Kit

1

1

High-throughput

0.691

High

560035

INAR1
Interferon alpha/beta receptor 1

1

4

High-throughput

0.691

High

560038

FGFR3
Fibroblast growth factor receptor 3

1

2

High-throughput

0.691

High

560043

TNFL9
Tumor necrosis factor ligand superfamily member 9

1

1

High-throughput

0.691

High

560048

BCAM
Basal cell adhesion molecule

1

1

High-throughput

0.691

High

560049

EPHA4
Ephrin type-A receptor 4

1

2

High-throughput

0.691

High

560056

I10R2
Interleukin-10 receptor subunit beta

1

2

High-throughput

0.691

High

560060

PTPRS
Receptor-type tyrosine-protein phosphatase S

1

3

High-throughput

0.691

High

560067

CDON
Cell adhesion molecule-related/down-regulated by oncogenes

1

2

High-throughput

0.691

High

560069

SDK2
Protein sidekick-2

1

2

High-throughput

0.691

High

560074

LRP10
Low-density lipoprotein receptor-related protein 10

1

1

High-throughput

0.691

High

560086

PTPRU
Receptor-type tyrosine-protein phosphatase U

1

1

High-throughput

0.691

High

560087

NEO1
Neogenin

1

2

High-throughput

0.691

High

560088

IGSF8
Immunoglobulin superfamily member 8

1

1

High-throughput

0.691

High

560116

LRP12
Low-density lipoprotein receptor-related protein 12

1

1

High-throughput

0.691

High

560118

ROBO1
Roundabout homolog 1

1

3

High-throughput

0.691

High

560090

AP2M1
AP-2 complex subunit mu

4

1

Small-scale

0.688

High

155262

NRP1
Neuropilin-1

1

0

High-throughput

0.656

High

277430

DGAT1
Diacylglycerol O-acyltransferase 1

1

0

High-throughput

0.656

High

311046

MPZL1
Myelin protein zero-like protein 1

1

0

High-throughput

0.656

High

474912

UBB
Polyubiquitin-B [Cleaved into: Ubiquitin]

1

0

High-throughput

0.656

High

560041

ABCD1
ATP-binding cassette sub-family D member 1

1

0

High-throughput

0.656

High

560042

BMR1A
Bone morphogenetic protein receptor type-1A

1

0

High-throughput

0.656

High

560046

S26A2
Sulfate transporter

1

0

High-throughput

0.656

High

560050

MFAP3
Microfibril-associated glycoprotein 3

1

0

High-throughput

0.656

High

560070

ZRAB3
DNA annealing helicase and endonuclease ZRANB3

1

0

High-throughput

0.656

High

560085

LPAR1
Lysophosphatidic acid receptor 1

1

0

High-throughput

0.656

High

560091

RB39B
Ras-related protein Rab-39B

1

0

High-throughput

0.656

High

560100

ULBP3
UL16-binding protein 3

1

0

High-throughput

0.656

High

560114

JAG2
Protein jagged-2

1

0

High-throughput

0.656

High

560110

PD1L1
Programmed cell death 1 ligand 1

1

7

Small-scale

0.618

High

560039

P85A
Phosphatidylinositol 3-kinase regulatory subunit alpha

3

6

Small-scale

0.611

High

560047

LRBA
Lipopolysaccharide-responsive and beige-like anchor protein

2

0

Small-scale

0.595

High

560059

MALL
MAL-like protein

2

0

High-throughput

0.580

High

214747

PM34
Peroxisomal membrane protein PMP34

1

0

High-throughput

0.578

High

267739

TAF5L
TAF5-like RNA polymerase II p300/CBP-associated factor-associated factor 65 kDa subunit 5L

1

0

High-throughput

0.578

High

560101

S2551
Mitochondrial nicotinamide adenine dinucleotide transporter SLC25A51

1

0

High-throughput

0.578

High

560034

CTLA4
Cytotoxic T-lymphocyte protein 4

1

1

Small-scale

0.575

High

560036

PTN2
Tyrosine-protein phosphatase non-receptor type 2

1

2

High-throughput

0.536

High

560052

I13R1
Interleukin-13 receptor subunit alpha-1

1

3

High-throughput

0.536

High

560053

EFNB1
Ephrin-B1

1

1

High-throughput

0.536

High

560098

TACAN
Ion channel TACAN

1

1

High-throughput

0.536

High

560105

PLCC
1-acyl-sn-glycerol-3-phosphate acyltransferase gamma

1

1

High-throughput

0.536

High

560064

2A5A
Serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit alpha isoform

1

0

Small-scale

0.529

High

129369

GOLI4
Golgi integral membrane protein 4

1

0

High-throughput

0.513

High

199576

B4GT5
Beta-1,4-galactosyltransferase 5

1

0

High-throughput

0.513

High

207191

SGCE
Epsilon-sarcoglycan

1

0

High-throughput

0.513

High

309560

GOSR1
Golgi SNAP receptor complex member 1

1

0

High-throughput

0.513

High

560037

FUT4
Alpha-(1,3)-fucosyltransferase 4

1

0

High-throughput

0.513

High

560057

GOGA2
Golgin subfamily A member 2

1

0

High-throughput

0.513

High

560066

OCLN
Occludin

1

0

High-throughput

0.513

High

560081

GOLM1
Golgi membrane protein 1

1

0

High-throughput

0.513

High

560082

RN149
E3 ubiquitin-protein ligase RNF149

1

0

High-throughput

0.513

High

560096

MYADM
Myeloid-associated differentiation marker

1

0

High-throughput

0.513

High

560099

FUT8
Alpha-(1,6)-fucosyltransferase

1

0

High-throughput

0.513

High

560102

GO45
Golgin-45

1

0

High-throughput

0.513

High

560106

ZDH18
Palmitoyltransferase ZDHHC18

1

0

High-throughput

0.513

High

560108

S39A1
Zinc transporter ZIP1

1

0

High-throughput

0.513

High

560109

PDXL2
Podocalyxin-like protein 2

1

0

High-throughput

0.513

High

560111

S53A1
Solute carrier family 53 member 1

1

0

High-throughput

0.513

High

560113

VANG2
Vang-like protein 2

1

0

High-throughput

0.513

High

49299

T120B
Transmembrane protein 120B

1

1

High-throughput

0.489

High

159876

HGS
Hepatocyte growth factor-regulated tyrosine kinase substrate

1

1

High-throughput

0.489

High

272791

TM1L1
TOM1-like protein 1

1

1

High-throughput

0.489

High

560107

PLCE
1-acyl-sn-glycerol-3-phosphate acyltransferase epsilon

1

1

High-throughput

0.489

High

238347

JAK2
Tyrosine-protein kinase JAK2

1

4

Small-scale

0.479

High

411585

LCK
Tyrosine-protein kinase Lck

1

3

Small-scale

0.479

High

411989

FYN
Tyrosine-protein kinase Fyn

1

3

Small-scale

0.479

High

433562

LYN
Tyrosine-protein kinase Lyn

1

3

Small-scale

0.479

High

560062

RPGF1
Rap guanine nucleotide exchange factor 1

1

0

Small-scale

0.458

High

58276

TM218
Transmembrane protein 218

2

0

High-throughput

0.316

High

560068

CTXN3
Cortexin-3

2

0

High-throughput

0.316

High

64170

CO061
Uncharacterized protein C15orf61

1

0

High-throughput

0.279

Low

165307

KHNYN
Protein KHNYN

1

0

High-throughput

0.279

Low

275488

CAN15
Calpain-15

1

0

High-throughput

0.279

Low

297896

ST65G
STAGA complex 65 subunit gamma

1

0

High-throughput

0.279

Low

560051

NOP14
Nucleolar protein 14

1

0

High-throughput

0.279

Low

560054

UBXN1
UBX domain-containing protein 1

1

0

High-throughput

0.279

Low

560055

FOXM1
Forkhead box protein M1

1

0

High-throughput

0.279

Low

560058

DYH14
Dynein axonemal heavy chain 14

1

0

High-throughput

0.279

Low

560061

PEX6
Peroxisomal ATPase PEX6

1

0

High-throughput

0.279

Low

560063

IQCB1
IQ calmodulin-binding motif-containing protein 1

1

0

High-throughput

0.279

Low

560065

ELF2
ETS-related transcription factor Elf-2

1

0

High-throughput

0.279

Low

560071

DEP1A
DEP domain-containing protein 1A

1

0

High-throughput

0.279

Low

560072

LTMD1
LETM1 domain-containing protein 1

1

0

High-throughput

0.279

Low

560073

NFRKB
Nuclear factor related to kappa-B-binding protein

1

0

High-throughput

0.279

Low

560075

VPS36
Vacuolar protein-sorting-associated protein 36

1

0

High-throughput

0.279

Low

560076

DEN6A
Protein DENND6A

1

0

High-throughput

0.279

Low

560077

MGAP
MAX gene-associated protein

1

0

High-throughput

0.279

Low

560078

PLPL6
Patatin-like phospholipase domain-containing protein 6

1

0

High-throughput

0.279

Low

560079

RBFA
Putative ribosome-binding factor A, mitochondrial

1

0

High-throughput

0.279

Low

560080

MINY1
Ubiquitin carboxyl-terminal hydrolase MINDY-1

1

0

High-throughput

0.279

Low

560083

RHBL4
Rhomboid-related protein 4

1

0

High-throughput

0.279

Low

560084

S35F5
Solute carrier family 35 member F5

1

0

High-throughput

0.279

Low

560089

TADA1
Transcriptional adapter 1

1

0

High-throughput

0.279

Low

560092

NGBR
Dehydrodolichyl diphosphate synthase complex subunit NUS1

1

0

High-throughput

0.279

Low

560093

MYO19
Unconventional myosin-XIX

1

0

High-throughput

0.279

Low

560094

P121A
Nuclear envelope pore membrane protein POM 121

1

0

High-throughput

0.279

Low

560095

FACR2
Fatty acyl-CoA reductase 2

1

0

High-throughput

0.279

Low

560097

NOC4L
Nucleolar complex protein 4 homolog

1

0

High-throughput

0.279

Low

560103

CUED2
CUE domain-containing protein 2

1

0

High-throughput

0.279

Low

560104

NSUN3
tRNA

1

0

High-throughput

0.279

Low

560112

PKHB1
Pleckstrin homology domain-containing family B member 1

1

0

High-throughput

0.279

Low

560115

MAN1
Inner nuclear membrane protein Man1

1

0

High-throughput

0.279

Low

560117

TAF6L
TAF6-like RNA polymerase II p300/CBP-associated factor-associated factor 65 kDa subunit 6L

1

0

High-throughput

0.279

Low

560045

STA5A
Signal transducer and activator of transcription 5A

1

0

Small-scale

0.238

Low


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Last updated: 15 Jul 2024