Protein: CDC27
Cell division cycle protein 27 homolog (Anaphase-promoting complex subunit 3) (APC3) (CDC27 homolog) (CDC27Hs) (H-NUC)

Gene: CDC27
Organism: Homo sapiens
Interactions: 223
UniProt ID: P30260

Gene Ontology (top 5):
GO:0005634 - nucleus
GO:0005654 - nucleoplasm
GO:0005680 - anaphase-promoting complex
GO:0005737 - cytoplasm
GO:0005813 - centrosome

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

672822

CDC16
Cell division cycle protein 16 homolog

25

17

Small-scale

0.990

High

672916

CDC23
Cell division cycle protein 23 homolog

20

17

Small-scale

0.987

High

672917

APC7
Anaphase-promoting complex subunit 7

20

18

Small-scale

0.986

High

672927

APC10
Anaphase-promoting complex subunit 10

11

14

Small-scale

0.973

High

672864

CDC26
Anaphase-promoting complex subunit CDC26

10

5

Small-scale

0.969

High

672874

APC16
Anaphase-promoting complex subunit 16

8

4

Small-scale

0.966

High

672772

CDC27
Cell division cycle protein 27 homolog

6

16

Small-scale

0.931

High

672885

APC13
Anaphase-promoting complex subunit 13

5

5

Small-scale

0.916

High

672797

APC15
Anaphase-promoting complex subunit 15

3

7

Small-scale

0.861

High

672820

CDC20
Cell division cycle protein 20 homolog

61

20

Small-scale

0.772

High

672926

FZR1
Fizzy-related protein homolog

35

20

Small-scale

0.769

High

672919

APC4
Anaphase-promoting complex subunit 4

33

8

Small-scale

0.769

High

672824

MD2L1
Mitotic spindle assembly checkpoint protein MAD2A

28

6

Small-scale

0.768

High

236886

BUB1B
Mitotic checkpoint serine/threonine-protein kinase BUB1 beta

25

17

Small-scale

0.767

High

672918

APC5
Anaphase-promoting complex subunit 5

19

9

Small-scale

0.763

High

672920

ANC2
Anaphase-promoting complex subunit 2

17

19

Small-scale

0.761

High

672889

APC1
Anaphase-promoting complex subunit 1

14

8

Small-scale

0.757

High

672923

FBX5
F-box only protein 5

8

7

Small-scale

0.750

High

211124

BUB3
Mitotic checkpoint protein BUB3

8

9

Small-scale

0.747

High

538478

CCNB1
G2/mitotic-specific cyclin-B1

7

8

Small-scale

0.738

High

672906

APC11
Anaphase-promoting complex subunit 11

7

8

Small-scale

0.735

High

672790

NEK2
Serine/threonine-protein kinase Nek2

6

10

Small-scale

0.730

High

672842

UBE2S
Ubiquitin-conjugating enzyme E2 S

5

4

Small-scale

0.704

High

672785

NOTC1
Neurogenic locus notch homolog protein 1

1

4

High-throughput

0.691

High

330179

PTTG1
Securin

5

0

Small-scale

0.680

High

672833

MDC1
Mediator of DNA damage checkpoint protein 1

3

15

Small-scale

0.678

High

275175

GRAP2
GRB2-related adapter protein 2

3

12

High-throughput

0.667

High

327737

TTLL1
Polyglutamylase complex subunit TTLL1

3

2

High-throughput

0.667

High

672774

RIR2
Ribonucleoside-diphosphate reductase subunit M2

3

2

High-throughput

0.667

High

672871

SH3K1
SH3 domain-containing kinase-binding protein 1

3

11

High-throughput

0.667

High

672794

PLK1
Serine/threonine-protein kinase PLK1

3

8

Small-scale

0.656

High

672793

PPP5
Serine/threonine-protein phosphatase 5

1

7

Small-scale

0.647

High

521748

CADH1
Cadherin-1

5

6

Small-scale

0.641

High

672776

TTK
Dual specificity protein kinase TTK

3

9

Small-scale

0.640

High

672845

ANO6
Anoctamin-6

2

2

High-throughput

0.628

High

672852

RN19B
E3 ubiquitin-protein ligase RNF19B

2

14

High-throughput

0.628

High

672860

KIF2B
Kinesin-like protein KIF2B

2

6

High-throughput

0.628

High

672899

ZN408
Zinc finger protein 408

2

3

High-throughput

0.628

High

294424

RECQ4
ATP-dependent DNA helicase Q4

1

8

High-throughput

0.618

High

349910

RASK
GTPase KRas

1

3

High-throughput

0.618

High

503512

HSP7C
Heat shock cognate 71 kDa protein

1

1

High-throughput

0.618

High

672803

RHOB
Rho-related GTP-binding protein RhoB

1

6

High-throughput

0.618

High

672807

PP2AA
Serine/threonine-protein phosphatase 2A catalytic subunit alpha isoform

1

5

Small-scale

0.618

High

672859

CUL9
Cullin-9

1

6

Small-scale

0.618

High

672840

SMAD2
Mothers against decapentaplegic homolog 2

2

6

Small-scale

0.611

High

351621

PENK
Proenkephalin-A [Cleaved into: Synenkephalin; Met-enkephalin

3

1

High-throughput

0.609

High

672897

MAGIX
PDZ domain-containing protein MAGIX

3

6

High-throughput

0.609

High

672827

PIN1
Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1

2

0

Small-scale

0.607

High

414186

RB
Retinoblastoma-associated protein

2

1

Small-scale

0.606

High

672798

PTEN
Phosphatidylinositol 3,4,5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase PTEN

1

2

Small-scale

0.599

High

672880

DCR1C
Protein artemis

2

0

High-throughput

0.585

High

160401

AURKA
Aurora kinase A

2

6

Small-scale

0.584

High

226620

PRKN
E3 ubiquitin-protein ligase parkin

2

18

High-throughput

0.584

High

243993

BRD4
Bromodomain-containing protein 4

2

13

High-throughput

0.584

High

590130

CCNA2
Cyclin-A2

2

8

Small-scale

0.584

High

672808

H31
Histone H3.1

2

6

High-throughput

0.584

High

672818

FOXM1
Forkhead box protein M1

2

1

Small-scale

0.584

High

672826

SQSTM
Sequestosome-1

2

4

High-throughput

0.584

High

672856

UBP37
Ubiquitin carboxyl-terminal hydrolase 37

2

6

Small-scale

0.584

High

672861

SIR6
NAD-dependent protein deacylase sirtuin-6

2

4

Small-scale

0.584

High

672870

CBP
CREB-binding protein

2

17

Small-scale

0.584

High

672876

AURKB
Aurora kinase B

2

6

Small-scale

0.584

High

672915

MD2L2
Mitotic spindle assembly checkpoint protein MAD2B

2

6

Small-scale

0.584

High

672848

Q5T8C6
Cell division cycle 16

1

17

High-throughput

0.575

High

672851

CP087
UPF0547 protein C16orf87

2

4

High-throughput

0.574

High

369057

ESR1
Estrogen receptor

2

19

High-throughput

0.571

High

672829

DYR1A
Dual specificity tyrosine-phosphorylation-regulated kinase 1A

2

7

High-throughput

0.571

High

672816

HSF2
Heat shock factor protein 2

1

4

Small-scale

0.561

High

672825

SKP2
S-phase kinase-associated protein 2

2

0

Small-scale

0.559

High

672893

CUED2
CUE domain-containing protein 2

2

0

Small-scale

0.559

High

206805

FOXO3
Forkhead box protein O3

1

3

High-throughput

0.554

High

672867

ELMO1
Engulfment and cell motility protein 1

1

1

Small-scale

0.552

High

602497

COMT
Catechol O-methyltransferase

1

0

High-throughput

0.549

High

672812

ID2
DNA-binding protein inhibitor ID-2

1

0

Small-scale

0.537

High

126433

FOXE1
Forkhead box protein E1

1

2

High-throughput

0.536

High

426579

H10
Histone H1.0

1

2

High-throughput

0.536

High

469952

H2AZ
Histone H2A.Z

1

4

High-throughput

0.536

High

564811

HMGA1
High mobility group protein HMG-I/HMG-Y

1

1

High-throughput

0.536

High

622367

CCND1
G1/S-specific cyclin-D1

1

9

Small-scale

0.536

High

672786

CAPZB
F-actin-capping protein subunit beta

1

1

High-throughput

0.536

High

672806

SKP1
S-phase kinase-associated protein 1

1

2

High-throughput

0.536

High

672817

SUH
Recombining binding protein suppressor of hairless

1

2

High-throughput

0.536

High

672828

SNW1
SNW domain-containing protein 1

1

4

High-throughput

0.536

High

672834

NUMA1
Nuclear mitotic apparatus protein 1

1

3

High-throughput

0.536

High

672843

H2B2E
Histone H2B type 2-E

1

6

High-throughput

0.536

High

672849

RSBN1
Lysine-specific demethylase 9

1

1

High-throughput

0.536

High

672869

THRSP
Thyroid hormone-inducible hepatic protein

1

1

High-throughput

0.536

High

672881

CDC5L
Cell division cycle 5-like protein

1

4

High-throughput

0.536

High

672886

FOXP3
Forkhead box protein P3

1

2

High-throughput

0.536

High

672887

FOXQ1
Forkhead box protein Q1

1

2

High-throughput

0.536

High

672890

NUCKS
Nuclear ubiquitous casein and cyclin-dependent kinase substrate 1

1

1

High-throughput

0.536

High

672896

RABE2
Rab GTPase-binding effector protein 2

1

3

High-throughput

0.536

High

672914

SRP68
Signal recognition particle subunit SRP68

1

1

High-throughput

0.536

High

672921

PO2F3
POU domain, class 2, transcription factor 3

1

3

High-throughput

0.536

High

672789

UBP11
Ubiquitin carboxyl-terminal hydrolase 11

1

7

High-throughput

0.515

High

672813

H11
Histone H1.1

1

2

High-throughput

0.515

High

672858

CC125
Coiled-coil domain-containing protein 125

1

1

High-throughput

0.515

High

536610

FPPS
Farnesyl pyrophosphate synthase

1

0

High-throughput

0.513

High

672839

TEAD2
Transcriptional enhancer factor TEF-4

1

0

High-throughput

0.513

High

672863

MCPH1
Microcephalin

1

0

Small-scale

0.513

High

672866

ZN526
Zinc finger protein 526

1

0

High-throughput

0.513

High

672883

CDCA3
Cell division cycle-associated protein 3

1

0

High-throughput

0.513

High

672908

CFA97
Cilia- and flagella-associated protein 97

1

3

High-throughput

0.506

High

475381

UBC
Polyubiquitin-C [Cleaved into: Ubiquitin]

1

5

High-throughput

0.501

High

672777

CTNB1
Catenin beta-1

1

6

Small-scale

0.501

High

672799

CKS1
Cyclin-dependent kinases regulatory subunit 1

1

2

Small-scale

0.501

High

672872

P5CR2
Pyrroline-5-carboxylate reductase 2

1

4

High-throughput

0.489

High

672932

LTOR2
Ragulator complex protein LAMTOR2

1

2

High-throughput

0.489

High

672875

CDCA5
Sororin

1

0

Small-scale

0.479

High

162427

XPO1
Exportin-1

1

10

High-throughput

0.479

High

208244

DCX
Neuronal migration protein doublecortin

1

2

Small-scale

0.479

High

305153

UBE4B
Ubiquitin conjugation factor E4 B

1

1

Small-scale

0.479

High

319132

BRD1
Bromodomain-containing protein 1

1

7

High-throughput

0.479

High

322231

STAU1
Double-stranded RNA-binding protein Staufen homolog 1

1

8

High-throughput

0.479

High

337363

ABL1
Tyrosine-protein kinase ABL1

1

4

High-throughput

0.479

High

346028

MYC
Myc proto-oncogene protein

1

5

High-throughput

0.479

High

412040

FYN
Tyrosine-protein kinase Fyn

1

4

High-throughput

0.479

High

417166

ENOA
Alpha-enolase

1

2

Small-scale

0.479

High

448296

GSTP1
Glutathione S-transferase P

1

2

Small-scale

0.479

High

487163

ANDR
Androgen receptor

1

18

Small-scale

0.479

High

517079

PCNA
Proliferating cell nuclear antigen

1

1

Small-scale

0.479

High

519132

KCRB
Creatine kinase B-type

1

2

Small-scale

0.479

High

519676

ANXA3
Annexin A3

1

3

Small-scale

0.479

High

552026

RFA2
Replication protein A 32 kDa subunit

1

8

High-throughput

0.479

High

557619

NCK1
SH2/SH3 adapter protein NCK1

1

11

High-throughput

0.479

High

569253

CEBPB
CCAAT/enhancer-binding protein beta

1

4

High-throughput

0.479

High

578283

PGAM1
Phosphoglycerate mutase 1

1

1

Small-scale

0.479

High

584881

RO52
E3 ubiquitin-protein ligase TRIM21

1

4

Small-scale

0.479

High

600089

TAF1
Transcription initiation factor TFIID subunit 1

1

20

Small-scale

0.479

High

631354

BRD2
Bromodomain-containing protein 2

1

20

High-throughput

0.479

High

650452

RFA1
Replication protein A 70 kDa DNA-binding subunit

1

6

High-throughput

0.479

High

655229

P85A
Phosphatidylinositol 3-kinase regulatory subunit alpha

1

2

High-throughput

0.479

High

656153

PSA5
Proteasome subunit alpha type-5

1

4

Small-scale

0.479

High

672773

WEE1
Wee1-like protein kinase

1

11

High-throughput

0.479

High

672775

H2B1B
Histone H2B type 1-B

1

6

Small-scale

0.479

High

672778

RFA3
Replication protein A 14 kDa subunit

1

5

High-throughput

0.479

High

672779

HXD13
Homeobox protein Hox-D13

1

2

Small-scale

0.479

High

672780

BRCA1
Breast cancer type 1 susceptibility protein

1

8

High-throughput

0.479

High

672782

CCNF
Cyclin-F

1

13

High-throughput

0.479

High

672783

GATA4
Transcription factor GATA-4

1

6

High-throughput

0.479

High

672784

ATRX
Transcriptional regulator ATRX

1

6

Small-scale

0.479

High

672787

NR2C2
Nuclear receptor subfamily 2 group C member 2

1

3

High-throughput

0.479

High

672788

MXI1
Max-interacting protein 1

1

3

Small-scale

0.479

High

672791

NEK3
Serine/threonine-protein kinase Nek3

1

12

High-throughput

0.479

High

672792

NUP98
Nuclear pore complex protein Nup98-Nup96

1

4

Small-scale

0.479

High

672795

TERA
Transitional endoplasmic reticulum ATPase

1

1

High-throughput

0.479

High

672800

WDR5
WD repeat-containing protein 5

1

7

Small-scale

0.479

High

672801

RS14
Small ribosomal subunit protein uS11

1

1

Small-scale

0.479

High

672804

H4
Histone H4

1

5

High-throughput

0.479

High

672805

GRB2
Growth factor receptor-bound protein 2

1

9

High-throughput

0.479

High

672809

SMAD3
Mothers against decapentaplegic homolog 3

1

6

Small-scale

0.479

High

672810

H33
Histone H3.3

1

6

High-throughput

0.479

High

672811

E2F1
Transcription factor E2F1

1

1

Small-scale

0.479

High

672814

HHEX
Hematopoietically-expressed homeobox protein HHEX

1

1

Small-scale

0.479

High

672815

KMT2A
Histone-lysine N-methyltransferase 2A

1

10

Small-scale

0.479

High

672819

EP300
Histone acetyltransferase p300

1

20

High-throughput

0.479

High

672821

TP53B
TP53-binding protein 1

1

9

High-throughput

0.479

High

672823

FADD
FAS-associated death domain protein

1

1

Small-scale

0.479

High

672830

TFDP1
Transcription factor Dp-1

1

1

Small-scale

0.479

High

672831

DCTN1
Dynactin subunit 1

1

1

High-throughput

0.479

High

672836

BRD3
Bromodomain-containing protein 3

1

13

High-throughput

0.479

High

672837

2A5A
Serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit alpha isoform

1

2

Small-scale

0.479

High

672838

RBBP5
Retinoblastoma-binding protein 5

1

8

Small-scale

0.479

High

672841

EZH2
Histone-lysine N-methyltransferase EZH2

1

9

High-throughput

0.479

High

672844

FBX43
F-box only protein 43

1

7

Small-scale

0.479

High

672850

DAB2P
Disabled homolog 2-interacting protein

1

1

Small-scale

0.479

High

672853

TRI67
Tripartite motif-containing protein 67

1

13

High-throughput

0.479

High

672854

PAXI1
PAX-interacting protein 1

1

9

High-throughput

0.479

High

672855

SPERI
Speriolin

1

4

Small-scale

0.479

High

672857

MIB1
E3 ubiquitin-protein ligase MIB1

1

2

Small-scale

0.479

High

672862

TNR6A
Trinucleotide repeat-containing gene 6A protein

1

11

Small-scale

0.479

High

672865

KI18A
Kinesin-like protein KIF18A

1

8

Small-scale

0.479

High

672868

ESR2
Estrogen receptor beta

1

19

High-throughput

0.479

High

672878

ELMO2
Engulfment and cell motility protein 2

1

1

Small-scale

0.479

High

672879

ZN363
RING finger and CHY zinc finger domain-containing protein 1

1

1

High-throughput

0.479

High

672882

TBX5
T-box transcription factor TBX5

1

2

High-throughput

0.479

High

672894

SMRCD
SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A containing DEAD/H box 1

1

6

High-throughput

0.479

High

672895

PKHA4
Pleckstrin homology domain-containing family A member 4

1

11

High-throughput

0.479

High

672898

EGLN3
Prolyl hydroxylase EGLN3

1

2

High-throughput

0.479

High

672900

PKHA5
Pleckstrin homology domain-containing family A member 5

1

13

Small-scale

0.479

High

672901

CHD8
Chromodomain-helicase-DNA-binding protein 8

1

1

High-throughput

0.479

High

672902

TRI36
E3 ubiquitin-protein ligase TRIM36

1

20

High-throughput

0.479

High

672903

BIRC6
Baculoviral IAP repeat-containing protein 6

1

4

Small-scale

0.479

High

672907

TLS1
Splicing factor C9orf78

1

3

High-throughput

0.479

High

672909

HECW2
E3 ubiquitin-protein ligase HECW2

1

8

High-throughput

0.479

High

672910

ASH2L
Set1/Ash2 histone methyltransferase complex subunit ASH2

1

3

Small-scale

0.479

High

672912

ZRAN1
Ubiquitin thioesterase ZRANB1

1

8

High-throughput

0.479

High

672928

TRI33
E3 ubiquitin-protein ligase TRIM33

1

18

Small-scale

0.479

High

672929

PHF8
Histone lysine demethylase PHF8

1

6

Small-scale

0.479

High

672930

MARE3
Microtubule-associated protein RP/EB family member 3

1

1

High-throughput

0.479

High

672931

NINL
Ninein-like protein

1

2

Small-scale

0.479

High

672934

TACC3
Transforming acidic coiled-coil-containing protein 3

1

2

Small-scale

0.479

High

672936

MD1L1
Mitotic spindle assembly checkpoint protein MAD1

1

1

Small-scale

0.479

High

672873

DCPS
m7GpppX diphosphatase

1

0

High-throughput

0.460

High

672892

ADNP
Activity-dependent neuroprotector homeobox protein

1

0

High-throughput

0.460

High

124577

CLIC1
Chloride intracellular channel protein 1

1

0

Small-scale

0.458

High

267129

GEMI
Geminin

1

0

Small-scale

0.458

High

562886

STMN1
Stathmin

1

0

Small-scale

0.458

High

589791

TBP
TATA-box-binding protein

1

0

Small-scale

0.458

High

672781

CDN1A
Cyclin-dependent kinase inhibitor 1

1

0

Small-scale

0.458

High

672796

IF6
Eukaryotic translation initiation factor 6

1

0

High-throughput

0.458

High

672802

RS13
Small ribosomal subunit protein uS15

1

0

Small-scale

0.458

High

672832

NBR1
Next to BRCA1 gene 1 protein

1

0

High-throughput

0.458

High

672835

MD2BP
MAD2L1-binding protein

1

0

Small-scale

0.458

High

672846

BOREA
Borealin

1

0

Small-scale

0.458

High

672884

PYM1
Partner of Y14 and mago

1

0

Small-scale

0.458

High

672888

MLP3B
Microtubule-associated proteins 1A/1B light chain 3B

1

0

High-throughput

0.458

High

672891

EPN3
Epsin-3

1

0

High-throughput

0.458

High

672905

HXC10
Homeobox protein Hox-C10

1

0

Small-scale

0.458

High

672911

REV1
DNA repair protein REV1

1

0

Small-scale

0.458

High

672922

NUDT5
ADP-sugar pyrophosphatase

1

0

Small-scale

0.458

High

672925

TPX2
Targeting protein for Xklp2

1

0

Small-scale

0.458

High

672933

ZN330
Zinc finger protein 330

1

0

High-throughput

0.458

High

672847

LRRK2
Leucine-rich repeat serine/threonine-protein kinase 2

1

3

High-throughput

0.445

High

384341

NTRK1
High affinity nerve growth factor receptor

1

4

High-throughput

0.437

High

672924

HECD1
E3 ubiquitin-protein ligase HECTD1

1

11

Small-scale

0.437

High

672935

EMIL1
EMILIN-1

1

2

Small-scale

0.437

High

672877

MR1L1
MORF4 family-associated protein 1-like 1

1

0

High-throughput

0.279

Low

672913

LTOR3
Ragulator complex protein LAMTOR3

1

0

High-throughput

0.279

Low

672904

GKN1
Gastrokine-1

1

0

High-throughput

0.251

Low

49603

LNP1
Leukemia NUP98 fusion partner 1

1

0

Small-scale

0.249

Low

526558

CCL4
C-C motif chemokine 4

1

0

Small-scale

0.249

Low


Service provided by Combinatics, Japan

Last updated: 15 Jul 2024