Protein: ADA15
Disintegrin and metalloproteinase domain-containing protein 15 (ADAM 15) (EC 3.4.24.-) (Metalloprotease RGD disintegrin protein) (Metalloproteinase-like, disintegrin-like, and cysteine-rich protein 15) (MDC-15) (Metargidin)

Gene: ADA15, ADAM15
Organism: Homo sapiens
Interactions: 72
UniProt ID: Q13444

Gene Ontology (top 5):
GO:0001525 - angiogenesis
GO:0001669 - acrosomal vesicle
GO:0001953 - negative regulation of cell-matrix adhesion
GO:0002418 - immune response to tumor cell
GO:0004222 - metalloendopeptidase activity

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

1034773

ADA33
Disintegrin and metalloproteinase domain-containing protein 33

2

12

High-throughput

0.811

High

924546

GRB2
Growth factor receptor-bound protein 2

4

20

Small-scale

0.707

High

522964

SRC
Proto-oncogene tyrosine-protein kinase Src

4

20

Small-scale

0.702

High

1034764

SNX33
Sorting nexin-33

4

20

Small-scale

0.696

High

532947

PRG2
Bone marrow proteoglycan

1

11

High-throughput

0.691

High

1034765

CLC2B
C-type lectin domain family 2 member B

1

20

High-throughput

0.691

High

1034782

SNX9
Sorting nexin-9

3

20

Small-scale

0.687

High

442824

HCK
Tyrosine-protein kinase HCK

3

20

Small-scale

0.680

High

411708

LCK
Tyrosine-protein kinase Lck

3

20

Small-scale

0.676

High

654311

CALX
Calnexin

3

11

High-throughput

0.650

High

173579

NPHP1
Nephrocystin-1

2

2

Small-scale

0.646

High

412180

FYN
Tyrosine-protein kinase Fyn

2

20

Small-scale

0.636

High

557680

NCK1
SH2/SH3 adapter protein NCK1

2

20

Small-scale

0.634

High

1034780

PACN3
Protein kinase C and casein kinase substrate in neurons protein 3

2

20

Small-scale

0.631

High

433748

LYN
Tyrosine-protein kinase Lyn

2

20

Small-scale

0.629

High

1034754

SPD2A
SH3 and PX domain-containing protein 2A

3

18

Small-scale

0.622

High

396587

ITB3
Integrin beta-3

1

16

Small-scale

0.618

High

1034775

FBX6
F-box only protein 6

2

9

High-throughput

0.584

High

49909

ODAM
Odontogenic ameloblast-associated protein

2

0

High-throughput

0.580

High

1034770

SH3G2
Endophilin-A1

1

20

Small-scale

0.573

High

970881

SP4
Transcription factor Sp4

1

1

High-throughput

0.573

High

1034748

FHL3
Four and a half LIM domains protein 3

1

4

High-throughput

0.573

High

298978

SRBS2
Sorbin and SH3 domain-containing protein 2

1

20

Small-scale

0.561

High

433344

YES
Tyrosine-protein kinase Yes

1

20

Small-scale

0.561

High

1034763

SH3R3
E3 ubiquitin-protein ligase SH3RF3

1

20

Small-scale

0.561

High

986371

BTK
Tyrosine-protein kinase BTK

1

20

Small-scale

0.536

High

1034767

OSTF1
Osteoclast-stimulating factor 1

1

14

Small-scale

0.536

High

318370

ECEL1
Endothelin-converting enzyme-like 1

1

3

High-throughput

0.536

High

514382

PSPC
Surfactant protein C

1

4

High-throughput

0.536

High

535633

EDN3
Endothelin-3

1

1

High-throughput

0.536

High

1034756

BRID5
BRICHOS domain-containing protein 5

1

2

High-throughput

0.536

High

1034757

LYPD4
Ly6/PLAUR domain-containing protein 4

1

2

High-throughput

0.536

High

1034779

MD2L2
Mitotic spindle assembly checkpoint protein MAD2B

2

4

Small-scale

0.526

High

177884

TMPS2
Transmembrane protease serine 2

1

18

High-throughput

0.515

High

658930

MK01
Mitogen-activated protein kinase 1

1

5

Small-scale

0.515

High

1034749

PTK6
Protein-tyrosine kinase 6

1

20

Small-scale

0.515

High

1034776

TMPS4
Transmembrane protease serine 4

1

18

High-throughput

0.515

High

1034772

FUT8
Alpha-(1,6)-fucosyltransferase

1

0

High-throughput

0.513

High

1034750

ARHG7
Rho guanine nucleotide exchange factor 7

1

7

Small-scale

0.512

High

1034751

ARHG6
Rho guanine nucleotide exchange factor 6

1

6

Small-scale

0.512

High

1034781

SHLB1
Endophilin-B1

1

16

Small-scale

0.512

High

537642

NCF1
Neutrophil cytosol factor 1

1

20

Small-scale

0.501

High

655355

P85A
Phosphatidylinositol 3-kinase regulatory subunit alpha

1

7

Small-scale

0.501

High

788990

TEC
Tyrosine-protein kinase Tec

1

20

Small-scale

0.501

High

996560

ITK
Tyrosine-protein kinase ITK/TSK

1

20

Small-scale

0.501

High

1034753

ITSN1
Intersectin-1

1

11

Small-scale

0.501

High

1034752

PCH2
Pachytene checkpoint protein 2 homolog

1

2

High-throughput

0.494

High

180123

SIA8E
Alpha-2,8-sialyltransferase 8E

1

2

High-throughput

0.489

High

1034774

SDF2L
Stromal cell-derived factor 2-like protein 1

1

7

High-throughput

0.489

High

205362

TGON2
Trans-Golgi network integral membrane protein 2

1

11

High-throughput

0.479

High

337463

ABL1
Tyrosine-protein kinase ABL1

1

20

Small-scale

0.479

High

344976

CYTN
Cystatin-SN

1

5

Small-scale

0.479

High

443077

ITA5
Integrin alpha-5

1

4

Small-scale

0.479

High

647571

MK03
Mitogen-activated protein kinase 3

1

5

Small-scale

0.479

High

648748

DPP4
Dipeptidyl peptidase 4

1

1

High-throughput

0.479

High

726516

TIMP3
Metalloproteinase inhibitor 3

1

5

Small-scale

0.479

High

1034747

CUL3
Cullin-3

1

6

High-throughput

0.479

High

1034758

LMBRL
Protein LMBR1L

1

3

High-throughput

0.479

High

1034759

SH3R1
E3 ubiquitin-protein ligase SH3RF1

1

20

Small-scale

0.479

High

1034760

TM11B
Transmembrane protease serine 11B

1

17

High-throughput

0.479

High

1034766

ESR2
Estrogen receptor beta

1

3

High-throughput

0.479

High

1034771

SRBS1
Sorbin and SH3 domain-containing protein 1

1

20

Small-scale

0.479

High

1034777

T106B
Transmembrane protein 106B

1

7

High-throughput

0.479

High

1034761

PLD3
5'-3' exonuclease PLD3

1

0

High-throughput

0.458

High

1034755

SNX30
Sorting nexin-30

1

19

Small-scale

0.457

High

1034778

RIM3A
RIMS-binding protein 3A

1

11

Small-scale

0.457

High

1029221

MD2L1
Mitotic spindle assembly checkpoint protein MAD2A

1

4

Small-scale

0.437

High

1034769

SPAG5
Sperm-associated antigen 5

1

2

Small-scale

0.417

High

868473

ATX1
Ataxin-1

2

0

High-throughput

0.316

High

740146

NUP62
Nuclear pore glycoprotein p62

1

0

High-throughput

0.299

High

1034762

BANP
Protein BANP

1

0

High-throughput

0.299

High

1034768

RBPMS
RNA-binding protein with multiple splicing

1

0

High-throughput

0.299

High


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Last updated: 15 Jul 2024