Protein: HOOK3
Protein Hook homolog 3 (h-hook3) (hHK3)

Gene: HOOK3
Organism: Homo sapiens
Interactions: 194
UniProt ID: Q86VS8

Gene Ontology (top 5):
GO:0000242 - pericentriolar material
GO:0005737 - cytoplasm
GO:0005801 - cis-Golgi network
GO:0005813 - centrosome
GO:0005874 - microtubule

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

1202479

HOOK1
Protein Hook homolog 1

7

17

Small-scale

0.969

High

1202419

HOOK3
Protein Hook homolog 3

3

18

Small-scale

0.837

High

1202460

AKTIP
AKT-interacting protein

7

4

Small-scale

0.751

High

1202428

FHI1B
FHF complex subunit HOOK-interacting protein 1B

6

13

Small-scale

0.739

High

1202437

HOOK2
Protein Hook homolog 2

1

17

Small-scale

0.713

High

1202485

TN13B
Tumor necrosis factor ligand superfamily member 13B

4

2

High-throughput

0.699

High

985760

FHI1A
FHF complex subunit HOOK-interacting protein 1A

4

13

High-throughput

0.697

High

216943

KIF1C
Kinesin-like protein KIF1C

3

13

Small-scale

0.667

High

1202462

ZC4H2
Zinc finger C4H2 domain-containing protein

3

1

High-throughput

0.667

High

1202470

IFT57
Intraflagellar transport protein 57 homolog

3

0

High-throughput

0.638

High

1022930

CDC16
Cell division cycle protein 16 homolog

2

1

High-throughput

0.628

High

1153784

KLH10
Kelch-like protein 10

2

6

High-throughput

0.628

High

1202471

MTMR4
Myotubularin-related protein 4

2

9

High-throughput

0.628

High

1113802

GRDN
Girdin

1

16

High-throughput

0.618

High

1202492

DC1L1
Cytoplasmic dynein 1 light intermediate chain 1

2

3

High-throughput

0.611

High

826466

FNTB
Protein farnesyltransferase subunit beta

3

2

High-throughput

0.609

High

1202420

CMTD1
Catechol O-methyltransferase domain-containing protein 1

3

1

High-throughput

0.609

High

1189592

K1C27
Keratin, type I cytoskeletal 27

3

20

High-throughput

0.607

High

200888

CTIF
CBP80/20-dependent translation initiation factor

3

3

High-throughput

0.596

High

231597

KIF1B
Kinesin-like protein KIF1B

2

13

High-throughput

0.584

High

1202486

ADIP
Afadin- and alpha-actinin-binding protein

2

1

High-throughput

0.584

High

1071116

RBP1
RalA-binding protein 1

2

12

High-throughput

0.574

High

1152344

CNDH2
Condensin-2 complex subunit H2

2

1

High-throughput

0.574

High

1201241

FHI2B
FHF complex subunit HOOK-interacting protein 2B

2

13

High-throughput

0.567

High

531488

K1C13
Keratin, type I cytoskeletal 13

2

20

High-throughput

0.553

High

1202442

PNMA5
Paraneoplastic antigen-like protein 5

2

6

High-throughput

0.553

High

1139922

FHI2A
FHF complex subunit HOOK interacting protein 2A

2

13

High-throughput

0.549

High

164137

ARHGA
Rho guanine nucleotide exchange factor 10

1

16

High-throughput

0.536

High

364952

FRIL
Ferritin light chain

1

3

High-throughput

0.536

High

535453

GFAP
Glial fibrillary acidic protein

1

20

High-throughput

0.536

High

675195

CLIP1
CAP-Gly domain-containing linker protein 1

1

18

High-throughput

0.536

High

683511

1433B
14-3-3 protein beta/alpha

1

20

High-throughput

0.536

High

862300

NUBP1
Cytosolic Fe-S cluster assembly factor NUBP1

1

1

High-throughput

0.536

High

869391

HAP1
Huntingtin-associated protein 1

1

18

High-throughput

0.536

High

933876

TBB4B
Tubulin beta-4B chain

1

6

High-throughput

0.536

High

1041949

CUL3
Cullin-3

1

20

High-throughput

0.536

High

1077011

MARE1
Microtubule-associated protein RP/EB family member 1

1

7

High-throughput

0.536

High

1202421

SKAP1
Src kinase-associated phosphoprotein 1

1

19

High-throughput

0.536

High

1202436

TRI52
E3 ubiquitin-protein ligase TRIM52

1

9

High-throughput

0.536

High

1202447

CAB45
45 kDa calcium-binding protein

1

9

High-throughput

0.536

High

1202453

DUS16
Dual specificity protein phosphatase 16

1

7

High-throughput

0.536

High

1202487

KLH20
Kelch-like protein 20

1

6

High-throughput

0.536

High

1051348

DCTN1
Dynactin subunit 1

1

19

High-throughput

0.515

High

1051598

DYHC1
Cytoplasmic dynein 1 heavy chain 1

1

3

High-throughput

0.515

High

497257

TAU
Microtubule-associated protein tau

1

8

Small-scale

0.501

High

280628

KRT34
Keratin, type I cuticular Ha4

1

20

High-throughput

0.489

High

280892

KRT37
Keratin, type I cuticular Ha7

1

20

High-throughput

0.489

High

639606

TNR5
Tumor necrosis factor receptor superfamily member 5

1

5

High-throughput

0.489

High

795985

MAGA8
Melanoma-associated antigen 8

1

7

High-throughput

0.489

High

864311

ITA8
Integrin alpha-8 [Cleaved into: Integrin alpha-8 heavy chain; Integrin alpha-8 light chain]

1

6

High-throughput

0.489

High

975449

PPARD
Peroxisome proliferator-activated receptor delta

1

14

High-throughput

0.489

High

1030996

GPR17
Uracil nucleotide/cysteinyl leukotriene receptor

1

8

High-throughput

0.489

High

1071246

K1H1
Keratin, type I cuticular Ha1

1

20

High-throughput

0.489

High

1139578

ANR22
Ankyrin repeat domain-containing protein 22

1

12

High-throughput

0.489

High

1202426

FAM9C
Protein FAM9C

1

2

High-throughput

0.489

High

1202427

SYCE1
Synaptonemal complex central element protein 1

1

3

High-throughput

0.489

High

1202434

RUBIC
Run domain Beclin-1-interacting and cysteine-rich domain-containing protein

1

1

High-throughput

0.489

High

1202450

FEM1A
Protein fem-1 homolog A

1

13

High-throughput

0.489

High

1202483

AP4E1
AP-4 complex subunit epsilon-1

1

7

Small-scale

0.489

High

838094

MEOX2
Homeobox protein MOX-2

1

11

High-throughput

0.481

High

1202463

4ET
Eukaryotic translation initiation factor 4E transporter

1

2

High-throughput

0.481

High

64814

TBKB1
TANK-binding kinase 1-binding protein 1

1

3

High-throughput

0.479

High

135460

PPP6
Serine/threonine-protein phosphatase 6 catalytic subunit

1

8

High-throughput

0.479

High

151070

DVL2
Segment polarity protein dishevelled homolog DVL-2

1

17

High-throughput

0.479

High

167096

ARHGB
Rho guanine nucleotide exchange factor 11

1

16

High-throughput

0.479

High

198273

DC1L2
Cytoplasmic dynein 1 light intermediate chain 2

1

3

High-throughput

0.479

High

201956

WDR62
WD repeat-containing protein 62

1

8

High-throughput

0.479

High

202768

TPD54
Tumor protein D54

1

1

High-throughput

0.479

High

230258

SI1L3
Signal-induced proliferation-associated 1-like protein 3

1

8

High-throughput

0.479

High

300926

HAUS5
HAUS augmin-like complex subunit 5

1

3

High-throughput

0.479

High

387029

P53
Cellular tumor antigen p53

1

7

High-throughput

0.479

High

504342

HSP7C
Heat shock cognate 71 kDa protein

1

8

High-throughput

0.479

High

513597

PYC
Pyruvate carboxylase, mitochondrial

1

8

High-throughput

0.479

High

517346

PCNA
Proliferating cell nuclear antigen

1

1

High-throughput

0.479

High

587620

NFKB1
Nuclear factor NF-kappa-B p105 subunit

1

14

High-throughput

0.479

High

626184

APC
Adenomatous polyposis coli protein

1

9

High-throughput

0.479

High

647069

1433T
14-3-3 protein theta

1

20

High-throughput

0.479

High

702938

KINH
Kinesin-1 heavy chain

1

8

High-throughput

0.479

High

725198

MYH10
Myosin-10

1

15

High-throughput

0.479

High

833147

VPS41
Vacuolar protein sorting-associated protein 41 homolog

1

8

Small-scale

0.479

High

846568

DUS3
Dual specificity protein phosphatase 3

1

8

High-throughput

0.479

High

876701

BRPF1
Peregrin

1

6

High-throughput

0.479

High

876838

NP1L1
Nucleosome assembly protein 1-like 1

1

4

High-throughput

0.479

High

929915

ACTG
Actin, cytoplasmic 2

1

19

High-throughput

0.479

High

978793

TF65
Transcription factor p65

1

5

High-throughput

0.479

High

990880

ZO1
Tight junction protein ZO-1

1

11

High-throughput

0.479

High

1015860

WASC5
WASH complex subunit 5

1

1

High-throughput

0.479

High

1033287

DC1I2
Cytoplasmic dynein 1 intermediate chain 2

1

6

High-throughput

0.479

High

1068588

PLEC
Plectin

1

20

High-throughput

0.479

High

1068781

PCM1
Pericentriolar material 1 protein

1

7

High-throughput

0.479

High

1145064

WAC2A
WASH complex subunit 2A

1

2

High-throughput

0.479

High

1158621

C2D1A
Coiled-coil and C2 domain-containing protein 1A

1

5

High-throughput

0.479

High

1170645

TRI67
Tripartite motif-containing protein 67

1

20

High-throughput

0.479

High

1200968

LUZP1
Leucine zipper protein 1

1

19

High-throughput

0.479

High

1202422

CEP97
Centrosomal protein of 97 kDa

1

3

High-throughput

0.479

High

1202423

MA7D3
MAP7 domain-containing protein 3

1

2

High-throughput

0.479

High

1202430

ANR52
Serine/threonine-protein phosphatase 6 regulatory ankyrin repeat subunit C

1

13

High-throughput

0.479

High

1202431

GOGA5
Golgin subfamily A member 5

1

18

High-throughput

0.479

High

1202432

ALMS1
Centrosome-associated protein ALMS1

1

4

High-throughput

0.479

High

1202433

DLG5
Disks large homolog 5

1

14

High-throughput

0.479

High

1202439

CEP63
Centrosomal protein of 63 kDa

1

18

High-throughput

0.479

High

1202441

RBM14
RNA-binding protein 14

1

5

High-throughput

0.479

High

1202443

SPAG5
Sperm-associated antigen 5

1

18

High-throughput

0.479

High

1202445

NP1L4
Nucleosome assembly protein 1-like 4

1

4

High-throughput

0.479

High

1202446

COR1B
Coronin-1B

1

12

High-throughput

0.479

High

1202451

TBB2B
Tubulin beta-2B chain

1

6

High-throughput

0.479

High

1202452

IFT27
Intraflagellar transport protein 27 homolog

1

9

High-throughput

0.479

High

1202456

KLC2
Kinesin light chain 2

1

10

High-throughput

0.479

High

1202457

CCDC8
Coiled-coil domain-containing protein 8

1

6

High-throughput

0.479

High

1202458

VPS16
Vacuolar protein sorting-associated protein 16 homolog

1

2

Small-scale

0.479

High

1202461

Q9HCK3
KIAA1569 protein

1

1

High-throughput

0.479

High

1202466

KLC4
Kinesin light chain 4

1

10

High-throughput

0.479

High

1202472

ABI2
Abl interactor 2

1

20

High-throughput

0.479

High

1202474

BCCIP
BRCA2 and CDKN1A-interacting protein

1

1

High-throughput

0.479

High

1202475

CING
Cingulin

1

17

High-throughput

0.479

High

1202476

AASS
Alpha-aminoadipic semialdehyde synthase, mitochondrial

1

1

High-throughput

0.479

High

1202478

ZRAN1
Ubiquitin thioesterase ZRANB1

1

15

High-throughput

0.479

High

1202481

MYO6
Unconventional myosin-VI

1

18

High-throughput

0.479

High

1202490

WAC2C
WASH complex subunit 2C

1

2

High-throughput

0.479

High

601049

MSRE
Macrophage scavenger receptor types I and II

1

8

Small-scale

0.470

High

1151098

Q6FHY5
MEOX2 protein

1

11

High-throughput

0.470

High

240408

SNX2
Sorting nexin-2

1

0

High-throughput

0.458

High

841471

BPL1
Biotin--protein ligase

1

0

High-throughput

0.458

High

1120242

CEP55
Centrosomal protein of 55 kDa

1

0

High-throughput

0.458

High

1164817

AFTIN
Aftiphilin

1

0

High-throughput

0.458

High

1202455

WDR11
WD repeat-containing protein 11

1

0

High-throughput

0.458

High

1202469

BSDC1
BSD domain-containing protein 1

1

0

High-throughput

0.458

High

1202482

SYNRG
Synergin gamma

1

0

High-throughput

0.458

High

56657

PIPSL
Putative PIP5K1A and PSMD4-like protein

1

3

High-throughput

0.445

High

1131755

CE170
Centrosomal protein of 170 kDa

1

11

High-throughput

0.445

High

132519

RCAS1
Receptor-binding cancer antigen expressed on SiSo cells

1

1

High-throughput

0.437

High

136042

ACACB
Acetyl-CoA carboxylase 2

1

8

High-throughput

0.437

High

166960

ANR28
Serine/threonine-protein phosphatase 6 regulatory ankyrin repeat subunit A

1

13

High-throughput

0.437

High

205612

TGON2
Trans-Golgi network integral membrane protein 2

1

3

High-throughput

0.437

High

215249

STRN
Striatin

1

11

High-throughput

0.437

High

246244

NBN
Nibrin

1

1

High-throughput

0.437

High

252843

ABCB7
Iron-sulfur clusters transporter ABCB7, mitochondrial

1

1

High-throughput

0.437

High

254813

COBL
Protein cordon-bleu

1

2

High-throughput

0.437

High

257195

PP6R2
Serine/threonine-protein phosphatase 6 regulatory subunit 2

1

7

High-throughput

0.437

High

280272

CBPD
Carboxypeptidase D

1

2

High-throughput

0.437

High

385106

NTRK1
High affinity nerve growth factor receptor

1

20

High-throughput

0.437

High

398270

PCCA
Propionyl-CoA carboxylase alpha chain, mitochondrial

1

8

High-throughput

0.437

High

398370

PCCB
Propionyl-CoA carboxylase beta chain, mitochondrial

1

5

High-throughput

0.437

High

418996

TPM3
Tropomyosin alpha-3 chain

1

19

High-throughput

0.437

High

444411

K1C19
Keratin, type I cytoskeletal 19

1

20

High-throughput

0.437

High

506617

BCR
Breakpoint cluster region protein

1

20

High-throughput

0.437

High

514859

MPRI
Cation-independent mannose-6-phosphate receptor

1

4

High-throughput

0.437

High

682878

HNRH1
Heterogeneous nuclear ribonucleoprotein H

1

6

High-throughput

0.437

High

708696

MCM5
DNA replication licensing factor MCM5

1

9

High-throughput

0.437

High

813592

CAPZB
F-actin-capping protein subunit beta

1

5

High-throughput

0.437

High

857166

CAZA1
F-actin-capping protein subunit alpha-1

1

7

High-throughput

0.437

High

891556

MYL6
Myosin light polypeptide 6

1

17

High-throughput

0.437

High

1024044

ACACA
Acetyl-CoA carboxylase 1

1

8

High-throughput

0.437

High

1052550

RCN2
Reticulocalbin-2

1

9

High-throughput

0.437

High

1061931

GAPD1
GTPase-activating protein and VPS9 domain-containing protein 1

1

12

High-throughput

0.437

High

1101661

AAK1
AP2-associated protein kinase 1

1

15

High-throughput

0.437

High

1103051

ATG2A
Autophagy-related protein 2 homolog A

1

3

High-throughput

0.437

High

1124900

ZN326
DBIRD complex subunit ZNF326

1

1

High-throughput

0.437

High

1126001

PP6R3
Serine/threonine-protein phosphatase 6 regulatory subunit 3

1

4

High-throughput

0.437

High

1145606

F91A1
Protein FAM91A1

1

1

High-throughput

0.437

High

1164677

C1TM
Monofunctional C1-tetrahydrofolate synthase, mitochondrial

1

3

High-throughput

0.437

High

1198350

PATL1
Protein PAT1 homolog 1

1

3

High-throughput

0.437

High

1202424

Z3H7A
Zinc finger CCCH domain-containing protein 7A

1

4

High-throughput

0.437

High

1202429

KRI1
Protein KRI1 homolog

1

1

High-throughput

0.437

High

1202435

RAD50
DNA repair protein RAD50

1

18

High-throughput

0.437

High

1202444

MCCA
Methylcrotonoyl-CoA carboxylase subunit alpha, mitochondrial

1

8

High-throughput

0.437

High

1202448

GPTC1
G patch domain-containing protein 1

1

2

High-throughput

0.437

High

1202449

WDR83
WD repeat domain-containing protein 83

1

9

High-throughput

0.437

High

1202454

BACH2
Transcription regulator protein BACH2

1

9

High-throughput

0.437

High

1202464

VPS45
Vacuolar protein sorting-associated protein 45

1

6

High-throughput

0.437

High

1202465

SYIM
Isoleucine--tRNA ligase, mitochondrial

1

2

High-throughput

0.437

High

1202467

TBC23
TBC1 domain family member 23

1

2

High-throughput

0.437

High

1202468

PAPD1
Poly(A) RNA polymerase, mitochondrial

1

1

High-throughput

0.437

High

1202473

F120A
Constitutive coactivator of PPAR-gamma-like protein 1

1

1

High-throughput

0.437

High

1202477

ZO2
Tight junction protein ZO-2

1

10

High-throughput

0.437

High

1202480

RAB21
Ras-related protein Rab-21

1

13

High-throughput

0.437

High

1202484

PHF8
Histone lysine demethylase PHF8

1

3

High-throughput

0.437

High

1202489

HBS1L
HBS1-like protein

1

1

High-throughput

0.437

High

1202491

HYOU1
Hypoxia up-regulated protein 1

1

11

High-throughput

0.437

High

1202493

WASF2
Actin-binding protein WASF2

1

3

High-throughput

0.437

High

1091128

WHAL1
Putative WASP homolog-associated protein with actin, membranes and microtubules-like protein 1

1

4

High-throughput

0.407

High

50439

SYCE3
Synaptonemal complex central element protein 3

2

0

High-throughput

0.328

High

1138353

CBPC6
Cytosolic carboxypeptidase 6

1

0

High-throughput

0.279

Low

1165298

LCTL
Lactase-like protein

1

0

High-throughput

0.279

Low

1202440

TMM74
Transmembrane protein 74

1

0

High-throughput

0.279

Low

269019

CSDE1
Cold shock domain-containing protein E1

1

0

High-throughput

0.249

Low

336778

CERU
Ceruloplasmin

1

0

High-throughput

0.249

Low

452829

DLDH
Dihydrolipoyl dehydrogenase, mitochondrial

1

0

High-throughput

0.249

Low

986524

GFPT1
Glutamine--fructose-6-phosphate aminotransferase [isomerizing] 1

1

0

High-throughput

0.249

Low

1202425

K319L
Dyslexia-associated protein KIAA0319-like protein

1

0

High-throughput

0.249

Low

1202438

LTV1
Protein LTV1 homolog

1

0

High-throughput

0.249

Low

1202459

OSBL3
Oxysterol-binding protein-related protein 3

1

0

High-throughput

0.249

Low

1202488

ACOT9
Acyl-coenzyme A thioesterase 9, mitochondrial

1

0

High-throughput

0.249

Low


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Last updated: 15 Jul 2024