Protein: CLH2
Clathrin heavy chain 2 (Clathrin heavy chain on chromosome 22) (CLH-22)

Gene: CLH2, CLTCL1
Organism: Homo sapiens
Interactions: 175
UniProt ID: P53675

Gene Ontology (top 5):
GO:0000278 - mitotic cell cycle
GO:0005198 - structural molecule activity
GO:0005770 - late endosome
GO:0005802 - trans-Golgi network
GO:0005819 - spindle

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

451653

CLCB
Clathrin light chain B

3

7

High-throughput

0.861

High

863925

CLH1
Clathrin heavy chain 1

3

7

High-throughput

0.847

High

451399

CLCA
Clathrin light chain A

3

11

Small-scale

0.839

High

863933

PICAL
Phosphatidylinositol-binding clathrin assembly protein

3

14

High-throughput

0.675

High

317718

STABP
STAM-binding protein

3

3

High-throughput

0.667

High

863937

RAB32
Ras-related protein Rab-32

3

5

High-throughput

0.667

High

429856

CATL1
Procathepsin L

3

0

High-throughput

0.638

High

444697

GNAI3
Guanine nucleotide-binding protein G(i) subunit alpha-3

3

0

High-throughput

0.638

High

864008

MLP3A
Microtubule-associated proteins 1A/1B light chain 3A

3

11

Small-scale

0.633

High

528819

CFTR
Cystic fibrosis transmembrane conductance regulator

2

3

High-throughput

0.628

High

863938

EPN4
Clathrin interactor 1

2

13

High-throughput

0.628

High

863989

STALP
AMSH-like protease

2

3

High-throughput

0.628

High

245161

CUTA
Protein CutA

2

0

High-throughput

0.602

High

863957

GALT7
N-acetylgalactosaminyltransferase 7

2

0

High-throughput

0.602

High

864027

NOP53
Ribosome biogenesis protein NOP53

2

0

High-throughput

0.602

High

864028

AAKG3
5'-AMP-activated protein kinase subunit gamma-3

2

0

High-throughput

0.602

High

863952

CDC73
Parafibromin

2

1

Small-scale

0.586

High

863928

RL6
Large ribosomal subunit protein eL6

2

0

High-throughput

0.585

High

134295

CCL21
C-C motif chemokine 21

2

1

High-throughput

0.574

High

786756

GRIA3
Glutamate receptor 3

2

2

High-throughput

0.574

High

863944

CCD27
Coiled-coil domain-containing protein 27

2

1

High-throughput

0.574

High

863962

WDR5B
WD repeat-containing protein 5B

2

4

High-throughput

0.574

High

863964

IT70A
Intraflagellar transport protein 70A

2

1

High-throughput

0.574

High

863969

IT70B
Intraflagellar transport protein 70B

2

1

High-throughput

0.574

High

124382

HIP1
Huntingtin-interacting protein 1

1

4

Small-scale

0.568

High

63134

CCD69
Coiled-coil domain-containing protein 69

2

1

High-throughput

0.558

High

303042

HEXI1
Protein HEXIM1

2

1

High-throughput

0.558

High

864037

SNX5
Sorting nexin-5

1

3

Small-scale

0.552

High

354377

HLAB
HLA class I histocompatibility antigen, B alpha chain

2

1

High-throughput

0.552

High

161338

MYPT1
Protein phosphatase 1 regulatory subunit 12A

1

3

High-throughput

0.536

High

161639

GAK
Cyclin-G-associated kinase

1

9

High-throughput

0.536

High

164839

SC16A
Protein transport protein Sec16A

1

3

High-throughput

0.536

High

237880

AP180
Clathrin coat assembly protein AP180

1

8

High-throughput

0.536

High

241158

TOM1
Target of Myb1 membrane trafficking protein

1

17

High-throughput

0.536

High

253737

AUXI
Auxilin

1

6

High-throughput

0.536

High

257959

DNJB6
DnaJ homolog subfamily B member 6

1

1

High-throughput

0.536

High

338174

EGFR
Epidermal growth factor receptor

1

7

Small-scale

0.536

High

369239

ESR1
Estrogen receptor

1

3

High-throughput

0.536

High

807290

RS10
Small ribosomal subunit protein eS10

1

4

High-throughput

0.536

High

812968

CAZA2
F-actin-capping protein subunit alpha-2

1

1

High-throughput

0.536

High

863921

B2MG
Beta-2-microglobulin [Cleaved into: Beta-2-microglobulin form pI 5.3]

1

2

High-throughput

0.536

High

863926

HNRPU
Heterogeneous nuclear ribonucleoprotein U

1

1

High-throughput

0.536

High

863929

TF65
Transcription factor p65

1

4

High-throughput

0.536

High

863935

CUL1
Cullin-1

1

5

High-throughput

0.536

High

863936

CUL3
Cullin-3

1

5

High-throughput

0.536

High

863942

NEDD8
NEDD8

1

1

High-throughput

0.536

High

863948

MT21C
Protein-lysine methyltransferase METTL21C

1

3

High-throughput

0.536

High

863949

K1C39
Keratin, type I cytoskeletal 39

1

1

High-throughput

0.536

High

863956

CSN6
COP9 signalosome complex subunit 6

1

1

High-throughput

0.536

High

863959

THOC4
THO complex subunit 4

1

1

High-throughput

0.536

High

863961

CAND1
Cullin-associated NEDD8-dissociated protein 1

1

2

High-throughput

0.536

High

863966

SFPA2
Pulmonary surfactant-associated protein A2

1

1

High-throughput

0.536

High

863978

DDX54
ATP-dependent RNA helicase DDX54

1

3

High-throughput

0.536

High

863982

CSN5
COP9 signalosome complex subunit 5

1

3

High-throughput

0.536

High

863983

TP4A1
Protein tyrosine phosphatase type IVA 1

1

6

High-throughput

0.536

High

863987

EDC3
Enhancer of mRNA-decapping protein 3

1

1

High-throughput

0.536

High

863990

EF2KT
Protein-lysine N-methyltransferase EEF2KMT

1

2

High-throughput

0.536

High

863992

MYO19
Unconventional myosin-XIX

1

4

High-throughput

0.536

High

863997

RIOK2
Serine/threonine-protein kinase RIO2

1

2

High-throughput

0.536

High

864000

WNK3
Serine/threonine-protein kinase WNK3

1

5

High-throughput

0.536

High

864025

GTSE1
G2 and S phase-expressed protein 1

1

1

High-throughput

0.536

High

864029

LIMA1
LIM domain and actin-binding protein 1

1

3

High-throughput

0.536

High

864031

RUVB2
RuvB-like 2

1

1

High-throughput

0.536

High

864034

HYOU1
Hypoxia up-regulated protein 1

1

6

High-throughput

0.536

High

863953

LDH6A
L-lactate dehydrogenase A-like 6A

1

2

High-throughput

0.515

High

127638

EF2K
Eukaryotic elongation factor 2 kinase

1

0

High-throughput

0.513

High

394389

A4
Amyloid-beta precursor protein

1

0

High-throughput

0.513

High

812869

RPGP1
Rap1 GTPase-activating protein 1

1

0

High-throughput

0.513

High

863918

GEMI4
Gem-associated protein 4

1

0

High-throughput

0.513

High

863919

APC15
Anaphase-promoting complex subunit 15

1

0

High-throughput

0.513

High

863923

X3CL1
Fractalkine

1

0

High-throughput

0.513

High

863932

NDK3
Nucleoside diphosphate kinase 3

1

0

High-throughput

0.513

High

863934

ASAH1
Acid ceramidase

1

0

High-throughput

0.513

High

863951

FXL22
F-box and leucine-rich protein 22

1

0

High-throughput

0.513

High

863963

JAZF1
Juxtaposed with another zinc finger protein 1

1

0

High-throughput

0.513

High

863975

ZNRF1
E3 ubiquitin-protein ligase ZNRF1

1

0

High-throughput

0.513

High

863988

NEIL1
Endonuclease 8-like 1

1

0

High-throughput

0.513

High

863996

CSN8
COP9 signalosome complex subunit 8

1

0

High-throughput

0.513

High

864006

OSBL5
Oxysterol-binding protein-related protein 5

1

0

High-throughput

0.513

High

864017

DMAP1
DNA methyltransferase 1-associated protein 1

1

0

High-throughput

0.513

High

864018

EXOS3
Exosome complex component RRP40

1

0

High-throughput

0.513

High

864020

DDX21
Nucleolar RNA helicase 2

1

0

High-throughput

0.513

High

864024

OCAD1
OCIA domain-containing protein 1

1

0

High-throughput

0.513

High

864030

PCS1N
ProSAAS

1

0

High-throughput

0.513

High

863998

APOL5
Apolipoprotein L5

1

0

High-throughput

0.493

High

126575

P2Y10
Putative P2Y purinoceptor 10

1

4

High-throughput

0.489

High

666472

ARI4A
AT-rich interactive domain-containing protein 4A

1

1

High-throughput

0.489

High

863939

ARI5B
AT-rich interactive domain-containing protein 5B

1

1

High-throughput

0.489

High

863943

DREB
Drebrin

1

3

High-throughput

0.489

High

863947

SNPC4
snRNA-activating protein complex subunit 4

1

3

High-throughput

0.489

High

863967

CFA52
Cilia- and flagella-associated protein 52

1

7

High-throughput

0.489

High

863977

PMFBP
Polyamine-modulated factor 1-binding protein 1

1

4

High-throughput

0.489

High

863985

KCD12
BTB/POZ domain-containing protein KCTD12

1

1

High-throughput

0.489

High

864001

GLIS2
Zinc finger protein GLIS2

1

1

High-throughput

0.489

High

864004

REXO4
RNA exonuclease 4

1

1

High-throughput

0.489

High

864012

PAAT
ATPase PAAT

1

1

High-throughput

0.489

High

864014

LIN7B
Protein lin-7 homolog B

1

5

High-throughput

0.489

High

864026

HPBP1
Hsp70-binding protein 1

1

2

High-throughput

0.489

High

864038

NPTN
Neuroplastin

1

1

High-throughput

0.489

High

148571

CTRO
Citron Rho-interacting kinase

1

2

High-throughput

0.479

High

209801

PRC1
Protein regulator of cytokinesis 1

1

3

High-throughput

0.479

High

308528

KI20A
Kinesin-like protein KIF20A

1

5

High-throughput

0.479

High

584351

TNR1A
Tumor necrosis factor receptor superfamily member 1A

1

2

High-throughput

0.479

High

808420

YAP1
Transcriptional coactivator YAP1

1

6

High-throughput

0.479

High

863922

H31
Histone H3.1

1

2

High-throughput

0.479

High

863930

EP300
Histone acetyltransferase p300

1

5

High-throughput

0.479

High

863931

TFCP2
Alpha-globin transcription factor CP2

1

1

High-throughput

0.479

High

863941

KIF14
Kinesin-like protein KIF14

1

1

High-throughput

0.479

High

863946

LARP7
La-related protein 7

1

3

High-throughput

0.479

High

863981

STAM1
Signal transducing adapter molecule 1

1

18

Small-scale

0.479

High

863984

CHM4C
Charged multivesicular body protein 4c

1

3

High-throughput

0.479

High

863986

SPDLY
Protein Spindly

1

3

High-throughput

0.479

High

863991

AURKB
Aurora kinase B

1

4

High-throughput

0.479

High

863995

RING2
E3 ubiquitin-protein ligase RING2

1

2

High-throughput

0.479

High

864007

CHM4B
Charged multivesicular body protein 4b

1

3

High-throughput

0.479

High

864013

ECT2
Protein ECT2

1

2

High-throughput

0.479

High

864015

PKHA2
Pleckstrin homology domain-containing family A member 2

1

3

Small-scale

0.479

High

864019

ANLN
Anillin

1

1

High-throughput

0.479

High

864032

FBW1A
F-box/WD repeat-containing protein 1A

1

6

High-throughput

0.479

High

326529

SNAI1
Zinc finger protein SNAI1

1

0

High-throughput

0.458

High

665834

PTN6
Tyrosine-protein phosphatase non-receptor type 6

1

0

High-throughput

0.458

High

863965

CEP57
Centrosomal protein of 57 kDa

1

0

High-throughput

0.458

High

217864

PRKY
Putative serine/threonine-protein kinase PRKY

1

3

High-throughput

0.445

High

306041

GBRAP
Gamma-aminobutyric acid receptor-associated protein

1

11

High-throughput

0.445

High

863920

GBRL2
Gamma-aminobutyric acid receptor-associated protein-like 2

1

11

High-throughput

0.445

High

863927

OCRL
Inositol polyphosphate 5-phosphatase OCRL

1

4

High-throughput

0.445

High

863973

CD177
CD177 antigen

1

2

Small-scale

0.445

High

864002

ZDHC5
Palmitoyltransferase ZDHHC5

1

1

High-throughput

0.445

High

864003

MLP3B
Microtubule-associated proteins 1A/1B light chain 3B

1

11

High-throughput

0.445

High

864005

GBRL1
Gamma-aminobutyric acid receptor-associated protein-like 1

1

11

High-throughput

0.445

High

329534

AGR2
Anterior gradient protein 2 homolog

1

1

High-throughput

0.437

High

346311

MYC
Myc proto-oncogene protein

1

2

High-throughput

0.437

High

552316

RFA2
Replication protein A 32 kDa subunit

1

2

High-throughput

0.437

High

650760

RFA1
Replication protein A 70 kDa DNA-binding subunit

1

2

High-throughput

0.437

High

720050

RFA3
Replication protein A 14 kDa subunit

1

1

High-throughput

0.437

High

863954

TRI67
Tripartite motif-containing protein 67

1

1

High-throughput

0.437

High

863955

MEPCE
7SK snRNA methylphosphate capping enzyme

1

1

High-throughput

0.437

High

863999

LGR4
Leucine-rich repeat-containing G-protein coupled receptor 4

1

1

High-throughput

0.437

High

864040

CDY2
Testis-specific chromodomain protein Y 2

1

1

High-throughput

0.437

High

863950

PVRIG
Transmembrane protein PVRIG

3

0

High-throughput

0.347

High

863940

ZN169
Zinc finger protein 169

2

0

High-throughput

0.328

High

863971

TM199
Transmembrane protein 199

2

0

High-throughput

0.328

High

863972

TTC9B
Tetratricopeptide repeat protein 9B

2

0

High-throughput

0.328

High

863974

SPX3
Sugar phosphate exchanger 3

2

0

High-throughput

0.328

High

863979

TCP1L
T-complex protein 10A homolog 1

2

0

High-throughput

0.328

High

864033

RXLT1
Ribitol-5-phosphate xylosyltransferase 1

2

0

High-throughput

0.328

High

863994

CD006
Uncharacterized protein encoded by LINC01587

2

0

High-throughput

0.318

High

51005

PL8L1
PLAC8-like protein 1

1

0

High-throughput

0.279

Low

234009

O10H2
Olfactory receptor 10H2

1

0

High-throughput

0.279

Low

275311

CD123
Translation initiation factor eIF2 assembly protein

1

0

High-throughput

0.279

Low

561295

CRIS2
Cysteine-rich secretory protein 2

1

0

High-throughput

0.279

Low

589126

TCO2
Transcobalamin-2

1

0

High-throughput

0.279

Low

595712

NTF3
Neurotrophin-3

1

0

High-throughput

0.279

Low

863917

GALC
Galactocerebrosidase

1

0

High-throughput

0.279

Low

863924

PRR3
Proline-rich protein 3

1

0

High-throughput

0.279

Low

863945

DB135
Beta-defensin 135

1

0

High-throughput

0.279

Low

863958

T150A
Transmembrane protein 150A

1

0

High-throughput

0.279

Low

863960

PIGZ
GPI mannosyltransferase 4

1

0

High-throughput

0.279

Low

863968

FGRL1
Fibroblast growth factor receptor-like 1

1

0

High-throughput

0.279

Low

863970

MESH1
Guanosine-3',5'-bis(diphosphate) 3'-pyrophosphohydrolase MESH1

1

0

High-throughput

0.279

Low

863980

CCG8
Voltage-dependent calcium channel gamma-8 subunit

1

0

High-throughput

0.279

Low

863993

VCIP1
Deubiquitinating protein VCPIP1

1

0

High-throughput

0.279

Low

864009

SIA7D
Alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3-N-acetyl-galactosaminide alpha-2,6-sialyltransferase

1

0

High-throughput

0.279

Low

864010

SPRNG
SREBP regulating gene protein

1

0

High-throughput

0.279

Low

864016

MET14
N6-adenosine-methyltransferase non-catalytic subunit

1

0

High-throughput

0.279

Low

864021

ABC3C
DNA dC->dU-editing enzyme APOBEC-3C

1

0

High-throughput

0.279

Low

864022

GKN1
Gastrokine-1

1

0

High-throughput

0.279

Low

864035

MB212
Protein mab-21-like 2

1

0

High-throughput

0.279

Low

864036

ZSC21
Zinc finger and SCAN domain-containing protein 21

1

0

High-throughput

0.279

Low

864039

HS3S4
Heparan sulfate glucosamine 3-O-sulfotransferase 4

1

0

High-throughput

0.279

Low

541233

GBRA1
Gamma-aminobutyric acid receptor subunit alpha-1

1

0

High-throughput

0.269

Low

863976

O13A1
Olfactory receptor 13A1

1

0

High-throughput

0.269

Low

864023

CZIB
CXXC motif containing zinc binding protein

1

0

High-throughput

0.269

Low

472832

H2AB2
Histone H2A-Bbd type 2/3

1

0

High-throughput

0.249

Low

864011

Q9H8E5
cDNA FLJ13705 fis, clone PLACE2000302

1

0

High-throughput

0.232

Low


Service provided by Combinatics, Japan

Last updated: 15 Jul 2024