Protein: Q7K306
Cyclin-dependent kinase 4, isoform A (EC 2.7.11.22) (Cyclin-dependent kinase 4, isoform B) (Cyclin-dependent kinase 4, isoform C) (Cyclin-dependent kinase 4, isoform D) (Cyclin-dependent kinase 4, isoform E) (LD31205p)

Gene: Q7K306, Cdk4
Organism: Drosophila melanogaster
Interactions: 93
UniProt ID: Q7K306

Gene Ontology (top 5):
GO:0000082 - G1/S transition of mitotic cell cycle
GO:0000307 - cyclin-dependent protein kinase holoenzyme complex
GO:0004693 - cyclin-dependent protein serine/threonine kinase activity
GO:0005524 - ATP binding
GO:0005634 - nucleus

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

1179435

Q7KUZ5
Cyclin D, isoform D

3

20

Small-scale

0.829

High

1179449

CYCG
Cyclin G

2

20

Small-scale

0.775

High

332667

PLK4
Serine/threonine-protein kinase PLK4

1

8

High-throughput

0.656

High

618450

CDK2
Cyclin-dependent kinase 2

1

15

High-throughput

0.656

High

625704

CCNC
Cyclin-C

1

20

High-throughput

0.656

High

872349

CCNE
G1/S-specific cyclin-E

1

20

High-throughput

0.656

High

1179451

Q961D1
Cyclin K, isoform A

1

20

High-throughput

0.656

High

1179464

Q9VGK8
Tyrosine-protein kinase

1

16

High-throughput

0.656

High

1179476

MSIR6
RNA-binding protein Musashi homolog Rbp6

1

5

High-throughput

0.656

High

1179480

Q9VZP3
Cyclin J, isoform A

1

20

High-throughput

0.656

High

283948

O76513
Cyclin-H

1

20

High-throughput

0.621

High

1179447

PAN3
PAN2-PAN3 deadenylation complex subunit PAN3

1

3

High-throughput

0.621

High

1179471

Q9VS55
CTCF

1

1

High-throughput

0.621

High

1179483

SF3B3
Splicing factor 3B subunit 3

1

5

High-throughput

0.621

High

184393

O17144
Cyclin-H

1

20

High-throughput

0.590

High

247440

MK38B
Mitogen-activated protein kinase p38b

1

19

High-throughput

0.590

High

618394

CDK1
Cyclin-dependent kinase 1

1

15

High-throughput

0.590

High

820726

CDK5
Cyclin-dependent kinase 5 homolog

1

15

High-throughput

0.590

High

823657

MAPK2
MAP kinase-activated protein kinase 2

1

5

High-throughput

0.590

High

955084

JNK
Stress-activated protein kinase JNK

1

18

High-throughput

0.590

High

1096792

CSKP
Peripheral plasma membrane protein CASK

1

2

High-throughput

0.590

High

1179443

HIPPO
Serine/threonine-protein kinase hippo

1

10

High-throughput

0.590

High

1179446

Q8TA44
CTCF

1

1

High-throughput

0.590

High

1179454

Q9I7T8
PAN2-PAN3 deadenylation complex subunit PAN3

1

1

High-throughput

0.590

High

1179477

Q9VXM1
LD22957p

1

20

High-throughput

0.590

High

1000997

EIF3B
Eukaryotic translation initiation factor 3 subunit B

1

5

High-throughput

0.587

High

1178735

GLIS2
Zinc finger protein GLIS2 homolog

1

6

High-throughput

0.587

High

1179455

CEG1A
Centaurin-gamma-1A

1

2

High-throughput

0.587

High

1179482

Q9W0A7
RabX5

1

1

High-throughput

0.587

High

1179445

Q8T9L6
Splicing factor 3B subunit 3

1

5

High-throughput

0.528

High

51274

GUS
Protein gustavus

1

7

High-throughput

0.508

High

284467

PP4C
Serine/threonine-protein phosphatase 4 catalytic subunit

1

12

High-throughput

0.508

High

428861

DFD
Homeotic protein deformed

1

9

High-throughput

0.508

High

447370

BCD
Homeotic protein bicoid

1

7

High-throughput

0.508

High

524619

PP12
Serine/threonine-protein phosphatase alpha-2 isoform

1

14

High-throughput

0.508

High

571938

CRN
Protein crooked neck

1

3

High-throughput

0.508

High

709156

ECR
Ecdysone receptor

1

8

High-throughput

0.508

High

737581

2ABA
Protein phosphatase PP2A 55 kDa regulatory subunit

1

4

High-throughput

0.508

High

990966

GELS
Gelsolin

1

3

High-throughput

0.508

High

1097573

ER
Protein enhancer of rudimentary

1

2

High-throughput

0.508

High

1099600

RAD51
DNA repair protein Rad51 homolog

1

1

High-throughput

0.508

High

1179434

ACOX1
Acyl-coenzyme A oxidase 1

1

2

High-throughput

0.508

High

1179438

Q8MLW7
X-box-binding protein 1

1

8

High-throughput

0.508

High

1179442

CSN3
COP9 signalosome complex subunit 3

1

3

High-throughput

0.508

High

1179450

Q95U38
Succinate--CoA ligase [ADP-forming] subunit beta, mitochondrial

1

1

High-throughput

0.508

High

1179452

Q9I7L0
LP01847p

1

3

High-throughput

0.508

High

1179461

FANCM
DEAD-box ATP-dependent DNA helicase Fancm

1

4

High-throughput

0.508

High

1179466

Q9VL21
LD11652p

1

4

High-throughput

0.508

High

1179467

Q9VL27
Alpha-galactosidase

1

1

High-throughput

0.508

High

1179475

Q9VUD3
GH07353p

1

11

High-throughput

0.508

High

1179486

Q9W1S5
Proteasome subunit beta

1

5

High-throughput

0.508

High

54269

A1Z9I6
Uncharacterized protein, isoform A

1

0

High-throughput

0.486

High

984909

RSMB
Small nuclear ribonucleoprotein-associated protein B

1

0

High-throughput

0.486

High

1096135

NELFD
Negative elongation factor D

1

0

High-throughput

0.486

High

1179444

Q8T965
Prefoldin subunit 3

1

0

High-throughput

0.486

High

1179453

Q9I7M1
Olfactory-specific 9

1

0

High-throughput

0.486

High

1179457

DAN
Protein distal antenna

1

0

High-throughput

0.486

High

1179458

Q9VCU8
LD15939p

1

0

High-throughput

0.486

High

1179472

FRY
Protein furry

1

0

High-throughput

0.486

High

1179473

Q9VTM2
2-(3-amino-3-carboxypropyl)histidine synthase subunit 1

1

0

High-throughput

0.486

High

1179479

LTOR4
Ragulator complex protein LAMTOR4 homolog

1

0

High-throughput

0.486

High

1179481

ECD
Protein ecdysoneless

1

0

High-throughput

0.486

High

1179488

Q9W3F1
RE21057p

1

0

High-throughput

0.486

High

81476

B7Z143
Protein interacting with Ttk69 and Sin3A, isoform D

1

1

High-throughput

0.481

High

1178938

Q7K148
Proteasome subunit beta

1

6

High-throughput

0.481

High

1179437

PANG2
Protein pangolin, isoform J

1

11

High-throughput

0.481

High

1179459

Q9VD04
Uncharacterized protein, isoform B

1

7

High-throughput

0.481

High

1179469

Q9VQ95
Testis EndoG-Like 3

1

1

High-throughput

0.481

High

1179485

Q9W1H7
Putative homeodomain protein

1

4

High-throughput

0.481

High

114627

M9PD17
Gigas, isoform B

1

3

Small-scale

0.479

High

1096411

STAT
Signal transducer and transcription activator

1

1

Small-scale

0.479

High

220818

O46070
EG:25E8.4 protein

1

1

High-throughput

0.464

High

1179463

Q9VGI6
FI06048p

1

2

High-throughput

0.464

High

1179468

POLZ2
DNA polymerase zeta subunit 2

1

1

High-throughput

0.464

High

1179470

Q9VRQ4
LD47944p

1

1

High-throughput

0.464

High

1179484

Q9W0Y0
RE57840p

1

1

High-throughput

0.464

High

283690

O76136
Homeodomain protein

1

9

High-throughput

0.457

High

1179439

Q8MS22
RE41430p

1

1

High-throughput

0.457

High

1179456

Q9NHX7
Proteasome subunit beta

1

6

High-throughput

0.457

High

1179460

Q9VD05
RT01151p

1

5

High-throughput

0.457

High

1179478

FBXW7
F-box/WD repeat-containing protein 7

1

6

High-throughput

0.457

High

52575

A1Z7M3
Notopleural, isoform A

1

3

High-throughput

0.439

High

115562

M9PFH3
Uncharacterized protein, isoform D

1

1

High-throughput

0.439

High

1179465

Q9VL01
FI06461p

1

3

High-throughput

0.439

High

954940

PANG1
Protein pangolin, isoforms A/H/I/S

1

8

High-throughput

0.417

High

1179436

Q86PE8
SD23103p

1

3

High-throughput

0.417

High

1179474

Q9VU23
Uncharacterized protein, isoform E

1

1

High-throughput

0.417

High

221036

LIP3
Lipase 3

1

0

High-throughput

0.265

Low

1179440

Q8SXL5
RE09177p

1

0

High-throughput

0.265

Low

1179441

Q8SXV4
RH68528p

1

0

High-throughput

0.265

Low

1179448

PGPLA
Peptidoglycan-recognition protein LA

1

0

High-throughput

0.265

Low

1179462

Q9VFA3
Uncharacterized protein, isoform A

1

0

High-throughput

0.265

Low

1179487

Q9W239
FI14129p

1

0

High-throughput

0.265

Low


Service provided by Combinatics, Japan

Last updated: 15 Jul 2024