Protein: GRAP
Growth factor receptor-bound protein 2 (Downstream of receptor kinase) (Protein enhancer of sevenless 2B)

Gene: GRAP, drk
Organism: Drosophila melanogaster
Interactions: 69
UniProt ID: Q08012

Gene Ontology (top 5):
GO:0001784 - phosphotyrosine residue binding
GO:0005118 - sevenless binding
GO:0005154 - epidermal growth factor receptor binding
GO:0005654 - nucleoplasm
GO:0005737 - cytoplasm

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

644366

SOS
Protein son of sevenless

6

20

Small-scale

0.944

High

382208

EGFR
Epidermal growth factor receptor

5

20

Small-scale

0.907

High

993221

DOS
Protein daughter of sevenless

3

20

Small-scale

0.855

High

112214

M9MRE1
PDGF- and VEGF-receptor related, isoform K

3

20

Small-scale

0.829

High

649302

DYN
Dynamin

2

20

Small-scale

0.806

High

526798

7LESS
Protein sevenless

2

20

Small-scale

0.768

High

665777

CSW
Tyrosine-protein phosphatase corkscrew

2

20

High-throughput

0.713

High

993198

CAD96
Tyrosine kinase receptor Cad96Ca

1

20

Small-scale

0.713

High

993195

Q9V3V3
Pez, isoform A

2

20

High-throughput

0.675

High

337676

SRC64
Tyrosine-protein kinase Src64B

1

19

High-throughput

0.656

High

957161

DAB
Protein disabled

3

20

Small-scale

0.655

High

220607

O46034
E3 ubiquitin-protein ligase CBL

2

20

Small-scale

0.643

High

55337

A1ZAN6
Rho guanine nucleotide exchange factor 2, isoform D

1

19

High-throughput

0.618

High

507710

KRAF1
Raf homolog serine/threonine-protein kinase Raf

1

20

High-throughput

0.618

High

993194

Q9V3C8
DShc protein

1

20

High-throughput

0.618

High

993202

Q9VDF4
Cortactin, isoform A

1

20

High-throughput

0.618

High

993206

Q9VHK4
Polychaetoid, isoform B

1

19

High-throughput

0.618

High

993211

Q9VUH6
Myopic

1

20

High-throughput

0.618

High

993213

Q9VWB7
LD06925p

1

8

High-throughput

0.618

High

993220

ACK
Activated Cdc42 kinase Ack

1

20

Small-scale

0.618

High

547615

DORS
Embryonic polarity protein dorsal

2

5

High-throughput

0.600

High

993226

Y34F
Uncharacterized protein CG43867

1

20

High-throughput

0.555

High

993193

ACKL
Activated Cdc42 kinase-like

1

20

High-throughput

0.553

High

993229

X2JFU3
Uncharacterized protein, isoform E

1

20

High-throughput

0.553

High

219699

SPY
Protein sprouty

2

19

High-throughput

0.552

High

993201

PFD5
Probable prefoldin subunit 5

1

1

High-throughput

0.508

High

993223

Q9W3N8
non-specific serine/threonine protein kinase

1

20

High-throughput

0.508

High

993186

Q7JNX6
Phosphoinositide 3-kinase

1

20

High-throughput

0.492

High

52725

PKN
Serine/threonine-protein kinase N

1

20

High-throughput

0.479

High

65062

A8DY50
Missing-in-metastasis, isoform B

1

10

High-throughput

0.479

High

284703

C3G
Guanine nucleotide-releasing factor 2

1

20

High-throughput

0.479

High

664604

1433Z
14-3-3 protein zeta

1

20

High-throughput

0.479

High

954994

1433E
14-3-3 protein epsilon

1

9

High-throughput

0.479

High

991221

EXPA
Protein expanded

1

20

High-throughput

0.479

High

993183

Q0E8H9
beta-N-acetylhexosaminidase

1

3

High-throughput

0.479

High

993184

Q0KHR5
Rho GTPase activating protein at 15B, isoform B

1

20

High-throughput

0.479

High

993188

Q7KV89
non-specific serine/threonine protein kinase

1

20

High-throughput

0.479

High

993190

Q8IPP3
Canoe, isoform D

1

20

High-throughput

0.479

High

993192

LARK
RNA-binding protein lark

1

11

High-throughput

0.479

High

993200

RGS
Regulator of G-protein signaling loco

1

6

High-throughput

0.479

High

993203

CYFIP
Cytoplasmic FMR1-interacting protein

1

10

High-throughput

0.479

High

993204

Q9VFD3
Uncharacterized protein, isoform B

1

20

High-throughput

0.479

High

993214

Q9VWL0
Mec2

1

5

High-throughput

0.479

High

993215

Q9VWL9
LD25711p

1

20

High-throughput

0.479

High

993218

AJUBA
LIM domain-containing protein jub

1

20

High-throughput

0.479

High

993225

MOODY
G-protein coupled receptor moody

1

16

High-throughput

0.479

High

993191

ENA
Protein enabled

1

20

Small-scale

0.470

High

993209

BL1S2
Biogenesis of lysosome-related organelles complex 1 subunit 2

1

2

High-throughput

0.464

High

993210

Q9VTW3
FI06571p

1

17

High-throughput

0.464

High

993224

Q9W424
RE50839p

1

14

High-throughput

0.464

High

993196

Q9VA35
CIN85 and CD2AP related, isoform A

1

0

High-throughput

0.458

High

993217

Q9VX08
LD10434p

1

0

High-throughput

0.458

High

993222

DIP2
Disco-interacting protein 2

1

0

High-throughput

0.458

High

993189

Q7KW26
MIP13633p

1

1

High-throughput

0.439

High

516241

NINL
Ninein homolog

1

15

High-throughput

0.437

High

984838

ATPB
ATP synthase subunit beta, mitochondrial

1

5

High-throughput

0.437

High

993185

Q5U0V7
phosphoinositide 5-phosphatase

1

20

High-throughput

0.437

High

993197

Q9VB22
LD33695p

1

4

High-throughput

0.437

High

993199

SAV
Scaffold protein salvador

1

19

High-throughput

0.437

High

993205

Q9VGQ1
Dihydrolipoyllysine-residue succinyltransferase component of 2-oxoglutarate dehydrogenase complex, mitochondrial

1

1

High-throughput

0.437

High

993207

Q9VN88
LD45836p

1

4

High-throughput

0.437

High

993212

Q9VVL7
Dihydrolipoyl dehydrogenase

1

1

High-throughput

0.437

High

993228

Q9XZT0
EG:34F3.10 protein

1

1

High-throughput

0.417

High

993227

IRS1
Insulin receptor substrate 1

1

12

High-throughput

0.381

High

993216

Q9VWM7
MIP16618p

2

0

High-throughput

0.310

High

55885

A1ZBC3
Uncharacterized protein

1

0

High-throughput

0.265

Low

993187

Q7KMK4
BcDNA.GH08789

1

0

High-throughput

0.249

Low

993208

Q9VRQ4
LD47944p

1

0

High-throughput

0.249

Low

993219

Q9VYR3
LP03706p

1

0

High-throughput

0.249

Low


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Last updated: 15 Jul 2024