Protein: POLO
Serine/threonine-protein kinase polo (EC 2.7.11.21)

Gene: POLO
Organism: Drosophila melanogaster
Interactions: 79
UniProt ID: P52304

Gene Ontology (top 5):
GO:0000278 - mitotic cell cycle
GO:0000776 - kinetochore
GO:0000915 - actomyosin contractile ring assembly
GO:0000922 - spindle pole
GO:0000940 - outer kinetochore

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

854019

POLO
Serine/threonine-protein kinase polo

2

17

Small-scale

0.812

High

854036

Q95TN8
Serine/threonine-protein kinase greatwall

1

18

Small-scale

0.724

High

854031

SPEN
Protein split ends

1

2

High-throughput

0.698

High

854073

DDB1
DNA damage-binding protein 1

1

9

High-throughput

0.698

High

54252

A1Z9I5
FI24033p1

1

7

Small-scale

0.680

High

854021

MTRM
Protein matrimony

4

0

Small-scale

0.675

High

854057

AURKB
Aurora kinase B

1

18

Small-scale

0.647

High

613173

MA205
205 kDa microtubule-associated protein

3

2

Small-scale

0.640

High

332659

PLK4
Serine/threonine-protein kinase PLK4

1

16

High-throughput

0.621

High

854026

Q7KT38
non-specific serine/threonine protein kinase

1

19

High-throughput

0.621

High

422738

NOTCH
Neurogenic locus Notch protein [Cleaved into: Processed neurogenic locus Notch protein]

1

5

High-throughput

0.618

High

594003

MPIP
M-phase inducer phosphatase

1

3

Small-scale

0.618

High

854059

Q9VP79
FI21431p1

2

1

High-throughput

0.595

High

854055

Q9VJ30
non-specific serine/threonine protein kinase

1

19

High-throughput

0.590

High

854060

CHNMO
Zinc finger protein chinmo

1

4

High-throughput

0.590

High

854049

Q9VGD3
Defective proboscis extension response 17, isoform A

1

1

High-throughput

0.587

High

854020

CNN
Centrosomin

2

8

Small-scale

0.584

High

854023

Q6NN29
Nuclear fallout, isoform E

1

12

Small-scale

0.561

High

854077

X2JFU3
Uncharacterized protein, isoform E

1

3

High-throughput

0.555

High

854028

MIRO
Mitochondrial Rho GTPase

1

5

Small-scale

0.553

High

854052

Q9VHC3
Blistery, isoform A

2

8

High-throughput

0.543

High

184269

TAP
Basic helix-loop-helix neural transcription factor TAP

1

4

High-throughput

0.541

High

611968

MYOD
Myogenic-determination protein

1

1

High-throughput

0.541

High

854022

OMB
Optomotor-blind protein

1

4

High-throughput

0.541

High

854025

MARS
Guanylate kinase-associated protein mars

1

2

High-throughput

0.541

High

854043

Q9U8L5
Dorsocross1, isoform A

1

4

High-throughput

0.541

High

854041

Q9I7U5
Centrobin, isoform A

1

10

Small-scale

0.536

High

854050

Q9VGU4
FI02822p

1

7

High-throughput

0.536

High

854065

Q9VX80
FI18040p1

1

3

High-throughput

0.528

High

854051

DALMA
Protein dalmatian

1

0

High-throughput

0.518

High

428859

DFD
Homeotic protein deformed

1

7

High-throughput

0.508

High

576058

JRA
Transcription factor Jra

1

7

High-throughput

0.508

High

771289

PSA2
Proteasome subunit alpha type-2

1

16

High-throughput

0.508

High

854045

SIR7
NAD-dependent protein deacetylase Sirt7

1

2

High-throughput

0.508

High

854038

KI10A
Kinesin-like protein Klp10A

1

9

Small-scale

0.501

High

854042

CLASP
CLIP-associating protein

1

6

Small-scale

0.501

High

854046

DCA10
DDB1- and CUL4-associated factor 10 homolog

1

9

High-throughput

0.494

High

854053

Q9VI23
LD40317p

1

1

High-throughput

0.494

High

844308

TAF1
Transcription initiation factor TFIID subunit 1

1

3

High-throughput

0.494

High

854076

AMOS
Basic helix-loop-helix transcription factor amos

1

4

High-throughput

0.494

High

365447

HSP83
Heat shock protein 83

1

20

High-throughput

0.492

High

183468

MBL
Protein muscleblind

1

0

High-throughput

0.486

High

854063

TPPP
Tubulin polymerization-promoting protein homolog

1

0

High-throughput

0.486

High

854039

Q961D7
LD07765p

1

1

High-throughput

0.481

High

854044

Q9V9T4
ATP-dependent chromatin assembly factor large subunit

1

10

High-throughput

0.481

High

854054

Q9VI72
Spindle assembly abnormal 4

1

9

High-throughput

0.481

High

854056

PDM2B
POU domain protein 2, isoform B

1

6

High-throughput

0.481

High

854066

Q9VXJ5
Disco-related, isoform A

1

1

High-throughput

0.481

High

854074

Q9XZ31
Anastral spindle 2, isoform A

1

1

High-throughput

0.481

High

854061

Q9VQS4
Spindly

1

0

Small-scale

0.480

High

854062

Q9VUA5
LD42058p

1

0

Small-scale

0.480

High

612593

DDX6
ATP-dependent RNA helicase me31b

1

2

High-throughput

0.479

High

854024

Q7JRJ9
Inner centromere protein, isoform A

1

4

Small-scale

0.479

High

854037

Q960D2
SD06673p

1

11

Small-scale

0.479

High

854048

Q9VEV3
LP07287p

1

10

High-throughput

0.479

High

854068

Q9W1G7
LD21576p

1

3

Small-scale

0.479

High

854072

Q9W4H9
Fizzy-related, isoform A

1

11

Small-scale

0.479

High

854058

MAEL
Protein maelstrom

1

0

Small-scale

0.458

High

185770

O18363
Knockout

1

1

High-throughput

0.457

High

679680

PDM2A
POU domain protein 2, isoform A

1

6

High-throughput

0.457

High

854035

Q95RV8
LD09043p

1

10

High-throughput

0.457

High

854040

Q9GSZ5
Disco-related protein

1

1

High-throughput

0.457

High

854067

Q9VZU6
BTB-VII protein domain

1

4

High-throughput

0.457

High

854075

FL2D
Pre-mRNA-splicing regulator female-lethal(2)D

1

9

Small-scale

0.445

High

54128

A1Z9E4
MIP03776p

1

1

High-throughput

0.439

High

854027

Q7YU88
SD08871p

1

1

High-throughput

0.439

High

854030

Q8MSY6
LD01372p

1

0

High-throughput

0.438

High

854033

Q8SZX6
LP03146p

1

1

High-throughput

0.417

High

854070

Q9W3X2
Uncharacterized protein, isoform A

1

4

High-throughput

0.417

High

183618

O16048
Kinesin-like protein

1

7

High-throughput

0.381

High

284271

O76904
EG:8D8.1 protein

1

0

High-throughput

0.282

High

854029

RS8
Small ribosomal subunit protein eS8

1

0

High-throughput

0.282

High

854064

Y3380
Uncharacterized protein CG13380

1

0

High-throughput

0.282

High

854069

Q9W3T0
RE73396p

1

0

High-throughput

0.282

High

854047

Q9VB45
GEO07187p1

1

0

High-throughput

0.265

Low

854071

Q9W3Z4
GH18625p

1

0

High-throughput

0.265

Low

854034

Q95RF6
LD34461p

1

0

High-throughput

0.249

Low

854032

Q8SYE7
RE65113p

1

0

High-throughput

0.238

Low


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Last updated: 15 Jul 2024