HitPredict

Interactor 1: IKBE (O00221)
NF-kappa-B inhibitor epsilon (NF-kappa-BIE) (I-kappa-B-epsilon) (IkB-E) (IkB-epsilon) (IkappaBepsilon)
Gene: NFKBIE

Interactor 2: PP6R3 (Q5H9R7)
Serine/threonine-protein phosphatase 6 regulatory subunit 3 (SAPS domain family member 3) (Sporulation-induced transcript 4-associated protein SAPL)
Gene: PPP6R3

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	14743216
Identification Methods	tandem affinity purification
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005654 - nucleoplasm GO:0005829 - cytosol
Homologous interactions	16

Homologous interactions

Color coding for hit scores

	1 500 Hs			1 873
+	Hs
		166945 ANR28_HUMAN (30-458): 1.63e-51: 190: 15.28		PP6R3_HUMAN (1-873): 0: 854: 100.00
+	Hs
		1126010 ANR44_HUMAN (16-364): 1.76e-36: 146: 12.50		PP6R3_HUMAN (1-873): 0: 854: 100.00
+	Hs
		166864 ANR28_HUMAN (30-458): 1.63e-51: 190: 15.28		PP6R2_HUMAN (1-870): 0: 766: 45.79
+	Hs
		1126012 ANR52_HUMAN (298-488): 3.21e-13: 74.3: 33.85		PP6R3_HUMAN (1-873): 0: 854: 100.00
+	Hs
		257199 ANR44_HUMAN (16-364): 1.76e-36: 146: 12.50		PP6R2_HUMAN (1-870): 0: 766: 45.79
+	Hs
		167044 ANR28_HUMAN (30-458): 1.63e-51: 190: 15.28		PP6R1_HUMAN (1-872): 0: 670: 44.00
+	Hs
		121552 IKBE_HUMAN (405-499): 6.48e-15: 79.1: 22.86		PP6R2_HUMAN (1-870): 0: 766: 45.79
+	Hs
		257200 ANR52_HUMAN (298-488): 3.21e-13: 74.3: 33.85		PP6R2_HUMAN (1-870): 0: 766: 45.79
+	Hs
		1237562 ANR44_HUMAN (16-364): 1.76e-36: 146: 12.50		PP6R1_HUMAN (1-872): 0: 670: 44.00
+	Hs
		883672 RIPK4_HUMAN (381-500): 5.47e-16: 82.9: 21.67		PP6R1_HUMAN (1-872): 0: 670: 44.00
+	Hs
		1330883 Q9H4D1_HUMAN (403-500): 4.98e-15: 79.8: 23.47		PP6R1_HUMAN (1-872): 0: 670: 44.00
+	Hs
		121602 IKBE_HUMAN (405-499): 6.48e-15: 79.1: 22.86		PP6R1_HUMAN (1-872): 0: 670: 44.00
+	Hs
		1239519 ANR52_HUMAN (298-488): 3.21e-13: 74.3: 33.85		PP6R1_HUMAN (1-872): 0: 670: 44.00
+	Mm
		103608 ANK3_MOUSE (1-346): 4.34e-56: 204: 15.23		ANK2_MOUSE (487-873): 5.84e-23: 108: 11.80
+	Hs
		978563 ANKK1_HUMAN (1-330): 1.67e-29: 124: 10.00		PRB3_HUMAN (642-872): 2.28e-09: 62.3: 13.03
+	Hs
		1336188 KDIS_HUMAN (5-297): 1.52e-22: 104: 10.88		MAGE1_HUMAN (626-872): 1.03e-10: 67.6: 8.84