HitPredict - High confidence protein-protein interactions

Protein: HTRA2
Serine protease HTRA2, mitochondrial (EC 3.4.21.108) (High temperature requirement protein A2) (DmHtrA2) (HtrA2) (Omi stress-regulated endoprotease) (dOmi) [Cleaved into: Serine protease HTRA2, mitochondrial, long; Serine protease HTRA2, mitochondrial, short]

Gene: HTRA2
Organism: Drosophila melanogaster
Interactions: 7
UniProt ID: Q9VFJ3

Gene Ontology (top 5):
GO:0004252 - serine-type endopeptidase activity
GO:0005739 - mitochondrion
GO:0005758 - mitochondrial intermembrane space
GO:0005829 - cytosol
GO:0006508 - proteolysis

Download interactions: TXT MITAB-2.5

Interaction	Interactor	Experiments	Homologs	Category	Interaction Score	Confidence
1173284	DIAP1 Death-associated inhibitor of apoptosis 1	2	15	Small-scale	0.634	High
1173361	DIAP2 Death-associated inhibitor of apoptosis 2	1	16	Small-scale	0.561	High
1473933	Q9VSX2 IP01061p	2	2	High-throughput	0.521	High
1473932	Q9VL01 Phenoloxidase-activating factor 2	1	0	High-throughput	0.486	High
1070727	PINK1 Serine/threonine-protein kinase Pink1, mitochondrial	1	2	Small-scale	0.479	High
1378431	Q95U20 Dynamin-like GTPase OPA1, mitochondrial	1	1	Small-scale	0.479	High
54576	PARL Presenilins-associated rhomboid-like protein, mitochondrial	1	0	Small-scale	0.458	High

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Last updated: 11Aug2025