Protein: DIAP1
Death-associated inhibitor of apoptosis 1 (EC 2.3.2.27) (Apoptosis 1 inhibitor) (E3 ubiquitin-protein ligase th) (Inhibitor of apoptosis 1) (Protein thread) (RING-type E3 ubiquitin transferase Diap1)

Gene: DIAP1
Organism: Drosophila melanogaster
Interactions: 37
UniProt ID: Q24306

Gene Ontology (top 5):
GO:0000209 - protein polyubiquitination
GO:0004842 - ubiquitin-protein transferase activity
GO:0004869 - cysteine-type endopeptidase inhibitor activity
GO:0005634 - nucleus
GO:0005737 - cytoplasm

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

1173292

DRONC
Caspase Dronc

12

20

Small-scale

0.980

High

144558

DRICE
Caspase drICE

6

20

Small-scale

0.941

High

145408

CASP1
Caspase-1

4

20

Small-scale

0.861

High

1173280

HIPPO
Serine/threonine-protein kinase hippo

3

5

Small-scale

0.820

High

1173293

Q9Y165
E2 ubiquitin-conjugating enzyme

3

20

Small-scale

0.806

High

1173282

Q9V3Y8
FI05319p

1

16

Small-scale

0.780

High

1173270

DIAP1
Death-associated inhibitor of apoptosis 1

2

16

Small-scale

0.768

High

1171957

HID
Cell death protein hid

12

1

Small-scale

0.755

High

1173273

RPR
Cell death protein rpr

9

2

Small-scale

0.750

High

1173274

GRIM
Cell death protein Grim

5

1

Small-scale

0.707

High

1173271

DIAP2
Death-associated inhibitor of apoptosis 2

1

17

Small-scale

0.692

High

683044

UBCD1
Ubiquitin-conjugating enzyme E2-17 kDa

1

20

Small-scale

0.665

High

1173284

HTRA2
Serine protease HTRA2, mitochondrial

2

15

Small-scale

0.634

High

583670

RS27A
Ubiquitin-ribosomal protein eS31 fusion protein [Cleaved into: Ubiquitin; Small ribosomal subunit protein eS31

1

5

Small-scale

0.618

High

1173285

UBC2M
Nedd8-conjugating enzyme UbcE2M

1

20

Small-scale

0.618

High

1173281

Q9V3Q4
thioredoxin-dependent peroxiredoxin

2

10

Small-scale

0.608

High

1173277

Q7JXB9
Endonuclease

1

2

Small-scale

0.578

High

234468

CTBP
C-terminal-binding protein

1

6

Small-scale

0.561

High

874919

IF4E
Eukaryotic translation initiation factor 4E1

1

3

Small-scale

0.561

High

1173289

UBR3
E3 ubiquitin-protein ligase Ubr3

2

0

Small-scale

0.559

High

638301

SINA
E3 ubiquitin-protein ligase sina

1

12

High-throughput

0.508

High

1173272

Q24326
receptor protein serine/threonine kinase

1

7

High-throughput

0.492

High

1173278

Q7KHK9
DREAM

1

20

High-throughput

0.492

High

1173275

Q6NQZ7
LD40663p

1

0

High-throughput

0.486

High

1173294

X2JIB5
Uncharacterized protein, isoform D

1

1

High-throughput

0.481

High

94965

E1JGN7
Heterogeneous nuclear ribonucleoprotein K, isoform E

1

7

Small-scale

0.479

High

682735

PROF
Profilin

1

3

Small-scale

0.479

High

827998

RAC1
Ras-related protein Rac1

1

11

Small-scale

0.479

High

1173276

Q7JQI1
Deubiquitinating apoptotic inhibitor, isoform A

1

20

Small-scale

0.479

High

1173279

TERA
Transitional endoplasmic reticulum ATPase TER94

1

1

Small-scale

0.479

High

1173288

Q9W246
Uncharacterized protein

1

1

High-throughput

0.464

High

1173286

Q9VVP8
FI02818p

1

0

Small-scale

0.458

High

1173287

Q9VZU6
BTB-VII protein domain

1

3

High-throughput

0.457

High

1173290

Q9W4F9
IP01388p

1

2

High-throughput

0.457

High

1173283

Q9VBA5
GM18993p

1

0

High-throughput

0.249

Low

1173291

Q9W528
LD31238p

1

0

High-throughput

0.249

Low


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Last updated: 11Aug2025