Protein: PGTB2
Geranylgeranyl transferase type-2 subunit beta (EC 2.5.1.60) (Geranylgeranyl transferase type II subunit beta) (GGTase-II-beta) (Rab geranyl-geranyltransferase subunit beta) (Rab GG transferase beta) (Rab GGTase beta) (Rab geranylgeranyltransferase subunit beta) (Type II protein geranyl-geranyltransferase subunit beta)

Gene: PGTB2, RABGGTB
Organism: Homo sapiens
Interactions: 87
UniProt ID: P53611

Gene Ontology (top 5):
GO:0004663 - Rab geranylgeranyltransferase activity
GO:0005829 - cytosol
GO:0005886 - plasma membrane
GO:0005968 - Rab-protein geranylgeranyltransferase complex
GO:0007601 - visual perception

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

863114

PGTA
Geranylgeranyl transferase type-2 subunit alpha

6

18

High-throughput

0.950

High

180841

YKT6
Synaptobrevin homolog YKT6

3

1

High-throughput

0.861

High

863109

PTAR1
Protein prenyltransferase alpha subunit repeat-containing protein 1

4

18

High-throughput

0.808

High

863094

TP4A2
Protein tyrosine phosphatase type IVA 2

4

4

Small-scale

0.702

High

863148

RAP2C
Ras-related protein Rap-2c

3

3

High-throughput

0.675

High

231386

PI51C
Phosphatidylinositol 4-phosphate 5-kinase type-1 gamma

3

2

High-throughput

0.667

High

301190

RHBT3
Rho-related BTB domain-containing protein 3

3

2

High-throughput

0.667

High

349213

RASH
GTPase HRas

3

4

High-throughput

0.667

High

486016

RAP2A
Ras-related protein Rap-2a

3

3

High-throughput

0.667

High

863092

NOTC2
Neurogenic locus notch homolog protein 2

3

1

High-throughput

0.667

High

863093

RB40B
Ras-related protein Rab-40B

3

6

High-throughput

0.667

High

863095

RAB31
Ras-related protein Rab-31

3

6

High-throughput

0.667

High

863096

GIT2
ARF GTPase-activating protein GIT2

3

1

High-throughput

0.667

High

863099

NCOA1
Nuclear receptor coactivator 1

3

1

High-throughput

0.667

High

863124

RB40C
Ras-related protein Rab-40C

3

5

High-throughput

0.667

High

863125

PI51A
Phosphatidylinositol 4-phosphate 5-kinase type-1 alpha

3

2

High-throughput

0.667

High

863142

NOTC3
Neurogenic locus notch homolog protein 3

3

1

High-throughput

0.667

High

863144

GIT1
ARF GTPase-activating protein GIT1

3

1

High-throughput

0.667

High

592176

RAB5A
Ras-related protein Rab-5A

3

6

High-throughput

0.657

High

863087

WDR4
tRNA

3

0

High-throughput

0.646

High

863136

B4GT7
Beta-1,4-galactosyltransferase 7

3

0

High-throughput

0.646

High

274816

PALM
Paralemmin-1

3

0

High-throughput

0.638

High

610700

KAPCB
cAMP-dependent protein kinase catalytic subunit beta

3

0

High-throughput

0.638

High

823360

PAXI
Paxillin

3

0

High-throughput

0.638

High

863097

I5P1
Inositol polyphosphate-5-phosphatase A

3

0

High-throughput

0.638

High

863098

ARHG6
Rho guanine nucleotide exchange factor 6

3

0

High-throughput

0.638

High

863103

BORA
Protein aurora borealis

3

0

High-throughput

0.638

High

863119

ZCCHL
Zinc finger CCCH-type antiviral protein 1-like

3

0

High-throughput

0.638

High

863120

PP16A
Protein phosphatase 1 regulatory subunit 16A

3

0

High-throughput

0.638

High

863126

MCMBP
Mini-chromosome maintenance complex-binding protein

3

0

High-throughput

0.638

High

863135

CACO1
Calcium-binding and coiled-coil domain-containing protein 1

3

0

High-throughput

0.638

High

863139

AKA11
A-kinase anchor protein 11

3

0

High-throughput

0.638

High

863143

TRI33
E3 ubiquitin-protein ligase TRIM33

3

0

High-throughput

0.638

High

845419

RAB9A
Ras-related protein Rab-9A

2

7

High-throughput

0.628

High

863121

FXL20
F-box/LRR-repeat protein 20

2

1

High-throughput

0.628

High

863134

RAB6B
Ras-related protein Rab-6B

2

4

High-throughput

0.628

High

348591

RASN
GTPase NRas

2

4

High-throughput

0.611

High

863089

RRAS2
Ras-related protein R-Ras2

2

5

High-throughput

0.611

High

863133

RAB9B
Ras-related protein Rab-9B

2

6

High-throughput

0.611

High

863150

PRC2C
Protein PRRC2C

2

1

High-throughput

0.611

High

863115

TP4A1
Protein tyrosine phosphatase type IVA 1

3

4

High-throughput

0.609

High

863123

PSKH2
Serine/threonine-protein kinase H2

3

1

High-throughput

0.609

High

863138

HOOK1
Protein Hook homolog 1

3

2

High-throughput

0.609

High

679217

KAP1
cAMP-dependent protein kinase type I-beta regulatory subunit

2

0

High-throughput

0.585

High

863116

RAB7B
Ras-related protein Rab-7b

2

8

High-throughput

0.574

High

863117

RAB37
Ras-related protein Rab-37

1

4

High-throughput

0.560

High

56604

PIPSL
Putative PIP5K1A and PSMD4-like protein

2

3

High-throughput

0.552

High

863110

TMM25
Transmembrane protein 25

1

0

High-throughput

0.549

High

642714

RAE2
Rab proteins geranylgeranyltransferase component A 2

1

1

High-throughput

0.536

High

863132

UBE2Z
Ubiquitin-conjugating enzyme E2 Z

1

2

High-throughput

0.536

High

863141

RAB26
Ras-related protein Rab-26

1

4

High-throughput

0.536

High

863106

NPSR1
Neuropeptide S receptor

1

0

High-throughput

0.518

High

863147

SHLB1
Endophilin-B1

1

0

High-throughput

0.518

High

863102

RRAGB
Ras-related GTP-binding protein B

1

0

High-throughput

0.513

High

627220

MCM3
DNA replication licensing factor MCM3

1

1

High-throughput

0.489

High

488630

ARAF
Serine/threonine-protein kinase A-Raf

1

0

Small-scale

0.486

High

591464

RAB3A
Ras-related protein Rab-3A

1

3

Small-scale

0.481

High

863107

TRI67
Tripartite motif-containing protein 67

1

2

High-throughput

0.479

High

863131

RAB17
Ras-related protein Rab-17

1

4

High-throughput

0.479

High

863140

FBXL2
F-box/LRR-repeat protein 2

1

1

Small-scale

0.479

High

863149

M4K5
Mitogen-activated protein kinase kinase kinase kinase 5

1

1

High-throughput

0.479

High

863090

RNF4
E3 ubiquitin-protein ligase RNF4

1

0

High-throughput

0.458

High

863100

CL16A
Protein CLEC16A

1

0

High-throughput

0.458

High

863105

LMBRL
Protein LMBR1L

1

0

High-throughput

0.458

High

863113

TIP
T-cell immunomodulatory protein

1

0

High-throughput

0.458

High

863129

MLP3B
Microtubule-associated proteins 1A/1B light chain 3B

1

0

High-throughput

0.458

High

863130

SHRPN
Sharpin

1

0

Small-scale

0.458

High

863137

ZRAN1
Ubiquitin thioesterase ZRANB1

1

0

High-throughput

0.458

High

863088

RAB8A
Ras-related protein Rab-8A

1

2

Small-scale

0.445

High

650757

RFA1
Replication protein A 70 kDa DNA-binding subunit

1

1

High-throughput

0.437

High

720047

RFA3
Replication protein A 14 kDa subunit

1

1

High-throughput

0.437

High

863101

LRRK2
Leucine-rich repeat serine/threonine-protein kinase 2

1

0

High-throughput

0.426

High

863128

ZDHC5
Palmitoyltransferase ZDHHC5

1

0

High-throughput

0.426

High

863091

FOXK1
Forkhead box protein K1

3

0

High-throughput

0.347

High

863104

ABRX1
BRCA1-A complex subunit Abraxas 1

3

0

High-throughput

0.347

High

863111

F219A
Protein FAM219A

3

0

High-throughput

0.347

High

863112

PGBD5
PiggyBac transposable element-derived protein 5

3

0

High-throughput

0.347

High

863118

TRM2B
tRNA

3

0

High-throughput

0.347

High

863127

GNB1L
Guanine nucleotide-binding protein subunit beta-like protein 1

3

0

High-throughput

0.347

High

863145

ACOT9
Acyl-coenzyme A thioesterase 9, mitochondrial

3

0

High-throughput

0.347

High

623567

IBP6
Insulin-like growth factor-binding protein 6

2

0

High-throughput

0.316

High

863108

TAFA1
Chemokine-like protein TAFA-1

1

0

High-throughput

0.299

High

441714

CFAH
Complement factor H

1

0

Small-scale

0.249

Low

552313

RFA2
Replication protein A 32 kDa subunit

1

0

High-throughput

0.249

Low

708585

MCM5
DNA replication licensing factor MCM5

1

0

High-throughput

0.249

Low

863122

MAGD4
Melanoma-associated antigen D4

1

0

High-throughput

0.249

Low

863146

AAR2
Protein AAR2 homolog

1

0

High-throughput

0.249

Low


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Last updated: 15 Jul 2024