Protein: MYB
Transcriptional activator Myb (Proto-oncogene c-Myb)

Gene: MYB
Organism: Homo sapiens
Interactions: 145
UniProt ID: P10242

Gene Ontology (top 5):
GO:0000122 - negative regulation of transcription by RNA polymerase II
GO:0000278 - mitotic cell cycle
GO:0000978 - RNA polymerase II cis-regulatory region sequence-specific DNA binding
GO:0000981 - DNA-binding transcription factor activity, RNA polymerase II-specific
GO:0001228 - DNA-binding transcription activator activity, RNA polymerase II-specific

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

486816

CBP
CREB-binding protein

7

10

Small-scale

0.971

High

486778

EP300
Histone acetyltransferase p300

6

13

Small-scale

0.937

High

261379

NCOR1
Nuclear receptor corepressor 1

2

6

Small-scale

0.806

High

486839

NLK
Serine/threonine-protein kinase NLK

2

20

Small-scale

0.657

High

486817

KAT2A
Histone acetyltransferase KAT2A

1

8

Small-scale

0.647

High

486772

UBC9
SUMO-conjugating enzyme UBC9

3

5

Small-scale

0.647

High

486830

HIPK2
Homeodomain-interacting protein kinase 2

2

20

Small-scale

0.636

High

486819

FBXW7
F-box/WD repeat-containing protein 7

2

4

Small-scale

0.624

High

486730

MYB
Transcriptional activator Myb

1

16

Small-scale

0.618

High

486829

PAIP1
Polyadenylate-binding protein-interacting protein 1

2

1

High-throughput

0.606

High

277898

PIAS1
E3 SUMO-protein ligase PIAS1

2

2

Small-scale

0.605

High

486852

TRAF6
TNF receptor-associated factor 6

2

3

Small-scale

0.601

High

165617

SET1A
Histone-lysine N-methyltransferase SETD1A

2

6

High-throughput

0.584

High

486797

LIN9
Protein lin-9 homolog

2

3

Small-scale

0.584

High

486747

PML
Protein PML

1

6

Small-scale

0.561

High

486753

RL4
Large ribosomal subunit protein uL4

1

1

Small-scale

0.561

High

486780

CHD3
Chromodomain-helicase-DNA-binding protein 3

1

12

Small-scale

0.561

High

486782

TIF1B
Transcription intermediary factor 1-beta

1

6

Small-scale

0.561

High

486826

SIN3A
Paired amphipathic helix protein Sin3a

1

5

Small-scale

0.561

High

486833

RENT2
Regulator of nonsense transcripts 2

1

1

High-throughput

0.561

High

486743

SP100
Nuclear autoantigen Sp-100

1

4

High-throughput

0.541

High

486748

CCND3
G1/S-specific cyclin-D3

1

5

High-throughput

0.541

High

486792

HLF
Hepatic leukemia factor

1

7

High-throughput

0.541

High

486811

PPM1K
Protein phosphatase Mn(2+)-dependent 1K

1

2

High-throughput

0.541

High

486733

SKI
Ski oncogene

1

0

Small-scale

0.537

High

486774

CLH1
Clathrin heavy chain 1

1

2

Small-scale

0.536

High

166824

ERC2
ERC protein 2

1

3

High-throughput

0.528

High

486767

SUMO2
Small ubiquitin-related modifier 2

1

2

Small-scale

0.527

High

486771

SUMO1
Small ubiquitin-related modifier 1

1

2

Small-scale

0.527

High

265106

MAF
Transcription factor Maf

1

1

Small-scale

0.527

High

486787

ZMY11
Zinc finger MYND domain-containing protein 11

1

7

Small-scale

0.527

High

486802

SND1
Staphylococcal nuclease domain-containing protein 1

1

1

Small-scale

0.527

High

486834

MYOZ2
Myozenin-2

1

0

High-throughput

0.518

High

486760

SMCA2
Probable global transcription activator SNF2L2

1

20

Small-scale

0.501

High

486788

CEBPE
CCAAT/enhancer-binding protein epsilon

1

8

Small-scale

0.501

High

486794

H31T
Histone H3.1t

1

4

Small-scale

0.501

High

486770

RBX1
E3 ubiquitin-protein ligase RBX1

1

0

Small-scale

0.480

High

116765

KIF2A
Kinesin-like protein KIF2A

1

5

High-throughput

0.479

High

152578

KMT2D
Histone-lysine N-methyltransferase 2D

1

9

High-throughput

0.479

High

167129

ZN536
Zinc finger protein 536

1

1

High-throughput

0.479

High

230303

ZC3H1
Zinc finger C3H1 domain-containing protein

1

2

High-throughput

0.479

High

231196

ZEB2
Zinc finger E-box-binding homeobox 2

1

2

High-throughput

0.479

High

265592

E2F6
Transcription factor E2F6

1

7

High-throughput

0.479

High

321694

WIZ
Protein Wiz

1

1

High-throughput

0.479

High

455015

PARP1
Poly [ADP-ribose] polymerase 1

1

5

Small-scale

0.479

High

486731

IRF1
Interferon regulatory factor 1

1

2

Small-scale

0.479

High

486732

HSP7C
Heat shock cognate 71 kDa protein

1

4

Small-scale

0.479

High

486734

NR2C1
Nuclear receptor subfamily 2 group C member 1

1

5

High-throughput

0.479

High

486735

IRF2
Interferon regulatory factor 2

1

2

Small-scale

0.479

High

486736

ZEP1
Zinc finger protein 40

1

1

High-throughput

0.479

High

486737

TAL1
T-cell acute lymphocytic leukemia protein 1

1

1

Small-scale

0.479

High

486739

EGR1
Early growth response protein 1

1

2

Small-scale

0.479

High

486740

NUCL
Nucleolin

1

4

Small-scale

0.479

High

486744

GATA3
Trans-acting T-cell-specific transcription factor GATA-3

1

2

Small-scale

0.479

High

486746

TYY1
Transcriptional repressor protein YY1

1

1

High-throughput

0.479

High

486752

BMI1
Polycomb complex protein BMI-1

1

4

Small-scale

0.479

High

486754

ZEB1
Zinc finger E-box-binding homeobox 1

1

2

High-throughput

0.479

High

486755

CUX1
Homeobox protein cut-like 1

1

5

High-throughput

0.479

High

486756

STA5A
Signal transducer and activator of transcription 5A

1

1

Small-scale

0.479

High

486758

CTCF
Transcriptional repressor CTCF

1

1

High-throughput

0.479

High

486759

CEBPA
CCAAT/enhancer-binding protein alpha

1

6

High-throughput

0.479

High

486762

BLM
RecQ-like DNA helicase BLM

1

6

High-throughput

0.479

High

486768

WDR5
WD repeat-containing protein 5

1

8

Small-scale

0.479

High

486776

PAX5
Paired box protein Pax-5

1

2

Small-scale

0.479

High

486777

KMT2A
Histone-lysine N-methyltransferase 2A

1

8

Small-scale

0.479

High

486779

NFIA
Nuclear factor 1 A-type

1

4

High-throughput

0.479

High

486781

RLF
Zinc finger protein Rlf

1

1

High-throughput

0.479

High

486784

CUL4A
Cullin-4A

1

3

Small-scale

0.479

High

486786

RBBP5
Retinoblastoma-binding protein 5

1

9

Small-scale

0.479

High

486790

EZH2
Histone-lysine N-methyltransferase EZH2

1

8

Small-scale

0.479

High

486791

DDB1
DNA damage-binding protein 1

1

5

Small-scale

0.479

High

486800

NIPBL
Nipped-B-like protein

1

5

High-throughput

0.479

High

486801

PAXI1
PAX-interacting protein 1

1

5

High-throughput

0.479

High

486803

KANL1
KAT8 regulatory NSL complex subunit 1

1

1

High-throughput

0.479

High

486804

POGZ
Pogo transposable element with ZNF domain

1

1

High-throughput

0.479

High

486805

EMSY
BRCA2-interacting transcriptional repressor EMSY

1

4

High-throughput

0.479

High

486807

ARI3B
AT-rich interactive domain-containing protein 3B

1

3

High-throughput

0.479

High

486808

MGAP
MAX gene-associated protein

1

2

High-throughput

0.479

High

486809

PHF6
PHD finger protein 6

1

4

High-throughput

0.479

High

486810

KMT2E
Inactive histone-lysine N-methyltransferase 2E

1

4

High-throughput

0.479

High

486813

KDM2B
Lysine-specific demethylase 2B

1

3

High-throughput

0.479

High

486814

GATD1
GATA zinc finger domain-containing protein 1

1

1

High-throughput

0.479

High

486815

BAP1
Ubiquitin carboxyl-terminal hydrolase BAP1

1

2

High-throughput

0.479

High

486818

KAT5
Histone acetyltransferase KAT5

1

2

Small-scale

0.479

High

486822

ZBTB9
Zinc finger and BTB domain-containing protein 9

1

7

High-throughput

0.479

High

486823

ZBT10
Zinc finger and BTB domain-containing protein 10

1

3

High-throughput

0.479

High

486824

EHMT2
Histone-lysine N-methyltransferase EHMT2

1

5

High-throughput

0.479

High

486825

CIC
Protein capicua homolog

1

6

High-throughput

0.479

High

486827

ARI3A
AT-rich interactive domain-containing protein 3A

1

3

High-throughput

0.479

High

486828

PCGF6
Polycomb group RING finger protein 6

1

4

High-throughput

0.479

High

486831

ZN644
Zinc finger protein 644

1

1

High-throughput

0.479

High

486832

EHMT1
Histone-lysine N-methyltransferase EHMT1

1

4

High-throughput

0.479

High

486836

CXXC1
CXXC-type zinc finger protein 1

1

7

High-throughput

0.479

High

486837

CHD7
Chromodomain-helicase-DNA-binding protein 7

1

12

High-throughput

0.479

High

486840

ASH2L
Set1/Ash2 histone methyltransferase complex subunit ASH2

1

5

Small-scale

0.479

High

486841

TRPS1
Zinc finger transcription factor Trps1

1

4

High-throughput

0.479

High

486843

LEF1
Lymphoid enhancer-binding factor 1

1

5

Small-scale

0.479

High

486845

KMT2B
Histone-lysine N-methyltransferase 2B

1

7

High-throughput

0.479

High

486846

PHF8
Histone lysine demethylase PHF8

1

5

High-throughput

0.479

High

486848

SMC3
Structural maintenance of chromosomes protein 3

1

5

High-throughput

0.479

High

486849

ZN148
Zinc finger protein 148

1

1

High-throughput

0.479

High

486850

ZN281
Zinc finger protein 281

1

1

High-throughput

0.479

High

92157

E9PAV9
G patch domain-containing protein 4

1

0

High-throughput

0.458

High

122462

MEN1
Menin

1

0

Small-scale

0.458

High

224279

RAD21
Double-strand-break repair protein rad21 homolog

1

0

High-throughput

0.458

High

396842

IL4
Interleukin-4

1

0

Small-scale

0.458

High

486741

PTMS
Parathymosin

1

0

High-throughput

0.458

High

486751

IL13
Interleukin-13

1

0

Small-scale

0.458

High

486757

RL34
Large ribosomal subunit protein eL34

1

0

High-throughput

0.458

High

486761

ZN131
Zinc finger protein 131

1

0

High-throughput

0.458

High

486763

ATX1
Ataxin-1

1

0

High-throughput

0.458

High

486764

AF17
Protein AF-17

1

0

High-throughput

0.458

High

486765

RL37A
Large ribosomal subunit protein eL43

1

0

High-throughput

0.458

High

486775

BEX3
Protein BEX3

1

0

High-throughput

0.458

High

486783

PIN1
Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1

1

0

Small-scale

0.458

High

486793

TAF9
Transcription initiation factor TFIID subunit 9

1

0

High-throughput

0.458

High

486795

BEND3
BEN domain-containing protein 3

1

0

High-throughput

0.458

High

486806

KAISO
Transcriptional regulator Kaiso

1

0

High-throughput

0.458

High

486812

ZN709
Zinc finger protein 709

1

0

High-throughput

0.458

High

486820

LMBL2
Lethal(3)malignant brain tumor-like protein 2

1

0

High-throughput

0.458

High

486821

FBXW5
F-box/WD repeat-containing protein 5

1

0

Small-scale

0.458

High

486838

KANL3
KAT8 regulatory NSL complex subunit 3

1

0

High-throughput

0.458

High

486842

DACH1
Dachshund homolog 1

1

0

High-throughput

0.458

High

486844

FBXL5
F-box/LRR-repeat protein 5

1

0

High-throughput

0.458

High

486847

SATB2
DNA-binding protein SATB2

1

0

High-throughput

0.458

High

486851

NOP16
Nucleolar protein 16

1

0

High-throughput

0.458

High

451345

CLCA
Clathrin light chain A

1

1

Small-scale

0.445

High

486738

CEBPB
CCAAT/enhancer-binding protein beta

1

7

Small-scale

0.445

High

486742

FLNA
Filamin-A

1

3

Small-scale

0.445

High

486785

SPTN1
Spectrin alpha chain, non-erythrocytic 1

1

9

Small-scale

0.445

High

486789

MK11
Mitogen-activated protein kinase 11

1

20

Small-scale

0.445

High

178057

NCAM2
Neural cell adhesion molecule 2

1

1

High-throughput

0.437

High

486796

NBPFE
Neuroblastoma breakpoint family member 14

1

1

High-throughput

0.437

High

486798

ZMYM4
Zinc finger MYM-type protein 4

1

1

High-throughput

0.437

High

391520

H2A1B
Histone H2A type 1-B/E

1

1

Small-scale

0.408

High

486749

H2B1B
Histone H2B type 1-B

1

2

Small-scale

0.408

High

486769

H4
Histone H4

1

2

Small-scale

0.408

High

486773

H31
Histone H3.1

1

4

Small-scale

0.408

High

486766

LYSC
Lysozyme C

1

0

Small-scale

0.269

Low

158308

PCD17
Protocadherin-17

1

0

High-throughput

0.249

Low

486745

COX7B
Cytochrome c oxidase subunit 7B, mitochondrial

1

0

High-throughput

0.249

Low

486750

SDC2
Syndecan-2

1

0

High-throughput

0.249

Low

486799

DCA15
DDB1- and CUL4-associated factor 15

1

0

High-throughput

0.249

Low

486835

ADA22
Disintegrin and metalloproteinase domain-containing protein 22

1

0

High-throughput

0.249

Low


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Last updated: 15 Jul 2024