Protein: MEX3C
RNA-binding E3 ubiquitin-protein ligase MEX3C (EC 2.3.2.27) (RING finger and KH domain-containing protein 2) (RING finger protein 194) (RING-type E3 ubiquitin transferase MEX3C)

Gene: MEX3C
Organism: Homo sapiens
Interactions: 160
UniProt ID: Q5U5Q3

Gene Ontology (top 5):
GO:0003415 - chondrocyte hypertrophy
GO:0003723 - RNA binding
GO:0005634 - nucleus
GO:0005737 - cytoplasm
GO:0045598 - regulation of fat cell differentiation

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

919746

UB2D2
Ubiquitin-conjugating enzyme E2 D2

2

20

Small-scale

0.778

High

959466

VIGLN
Vigilin

2

17

Small-scale

0.737

High

1137379

ZCCHV
Zinc finger CCCH-type antiviral protein 1

2

6

Small-scale

0.737

High

516551

PABP1
Polyadenylate-binding protein 1

4

6

Small-scale

0.676

High

909657

1433E
14-3-3 protein epsilon

4

3

Small-scale

0.672

High

982114

1433F
14-3-3 protein eta

3

14

Small-scale

0.650

High

895808

UB2D3
Ubiquitin-conjugating enzyme E2 D3

1

20

Small-scale

0.647

High

932529

UB2L3
Ubiquitin-conjugating enzyme E2 L3

1

20

High-throughput

0.647

High

1137371

MEX3C
RNA-binding E3 ubiquitin-protein ligase MEX3C

1

14

Small-scale

0.647

High

270653

MYCB2
E3 ubiquitin-protein ligase MYCBP2

3

3

Small-scale

0.633

High

890700

PTEN
Phosphatidylinositol 3,4,5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase PTEN

2

2

Small-scale

0.629

High

638307

RBTN2
Rhombotin-2

2

4

High-throughput

0.628

High

896460

UBE2N
Ubiquitin-conjugating enzyme E2 N

1

20

Small-scale

0.618

High

1033114

UB2V1
Ubiquitin-conjugating enzyme E2 variant 1

1

20

Small-scale

0.618

High

1071901

PCBP1
Poly(rC)-binding protein 1

1

10

High-throughput

0.618

High

1086903

UBE2S
Ubiquitin-conjugating enzyme E2 S

1

20

Small-scale

0.618

High

1137376

MEX3B
RNA-binding protein MEX3B

1

5

High-throughput

0.618

High

1137382

MEX3D
RNA-binding protein MEX3D

1

16

High-throughput

0.618

High

925899

AP2B1
AP-2 complex subunit beta

4

7

Small-scale

0.613

High

321566

AP2A1
AP-2 complex subunit alpha-1

3

5

Small-scale

0.585

High

1137407

CNOT7
CCR4-NOT transcription complex subunit 7

2

3

Small-scale

0.584

High

1137405

IF2B1
Insulin-like growth factor 2 mRNA-binding protein 1

1

14

Small-scale

0.575

High

817681

PI42A
Phosphatidylinositol 5-phosphate 4-kinase type-2 alpha

2

2

High-throughput

0.574

High

653285

PYR1
Multifunctional protein CAD

2

2

Small-scale

0.571

High

789835

LPPRC
Leucine-rich PPR motif-containing protein, mitochondrial

2

1

Small-scale

0.571

High

932742

EF1A1
Elongation factor 1-alpha 1

2

5

Small-scale

0.571

High

994205

DHX9
ATP-dependent RNA helicase A

2

14

Small-scale

0.571

High

1019528

ILF2
Interleukin enhancer-binding factor 2

2

6

Small-scale

0.571

High

1029518

TIF1B
Transcription intermediary factor 1-beta

2

5

Small-scale

0.571

High

1137374

PRP8
Pre-mRNA-processing-splicing factor 8

2

2

Small-scale

0.571

High

1137393

UBP7
Ubiquitin carboxyl-terminal hydrolase 7

1

8

Small-scale

0.534

High

519010

PIP
Prolactin-inducible protein

1

0

High-throughput

0.513

High

61384

CNOT1
CCR4-NOT transcription complex subunit 1

1

3

Small-scale

0.479

High

117727

MYO1C
Unconventional myosin-Ic

1

7

Small-scale

0.479

High

118873

GTPB1
GTP-binding protein 1

1

8

Small-scale

0.479

High

127518

RPOM
DNA-directed RNA polymerase, mitochondrial

1

1

Small-scale

0.479

High

162846

XPO1
Exportin-1

1

8

High-throughput

0.479

High

257364

CNOT3
CCR4-NOT transcription complex subunit 3

1

6

Small-scale

0.479

High

300180

PRP6
Pre-mRNA-processing factor 6

1

4

Small-scale

0.479

High

321905

RIGI
Antiviral innate immune response receptor RIG-I

1

13

Small-scale

0.479

High

325215

AIFM1
Apoptosis-inducing factor 1, mitochondrial

1

3

Small-scale

0.479

High

374370

RAF1
RAF proto-oncogene serine/threonine-protein kinase

1

4

High-throughput

0.479

High

382020

G3P
Glyceraldehyde-3-phosphate dehydrogenase

1

4

Small-scale

0.479

High

472706

FBSP1
F-box/SPRY domain-containing protein 1

1

4

High-throughput

0.479

High

502198

BIP
Endoplasmic reticulum chaperone BiP

1

5

Small-scale

0.479

High

607086

UBA1
Ubiquitin-like modifier-activating enzyme 1

1

3

Small-scale

0.479

High

684100

1433S
14-3-3 protein sigma

1

14

High-throughput

0.479

High

818140

SOX2
Transcription factor SOX-2

1

3

High-throughput

0.479

High

877294

DSRAD
Double-stranded RNA-specific adenosine deaminase

1

7

Small-scale

0.479

High

944281

PRKDC
DNA-dependent protein kinase catalytic subunit

1

4

Small-scale

0.479

High

1019788

ILF3
Interleukin enhancer-binding factor 3

1

11

Small-scale

0.479

High

1041765

CUL3
Cullin-3

1

5

High-throughput

0.479

High

1045127

RUNX3
Runt-related transcription factor 3

1

2

Small-scale

0.479

High

1049475

SAFB2
Scaffold attachment factor B2

1

11

Small-scale

0.479

High

1049574

EIF3A
Eukaryotic translation initiation factor 3 subunit A

1

5

Small-scale

0.479

High

1058107

BMS1
Ribosome biogenesis protein BMS1 homolog

1

3

Small-scale

0.479

High

1092835

HNRL2
Heterogeneous nuclear ribonucleoprotein U-like protein 2

1

7

Small-scale

0.479

High

1119427

PAN2
PAN2-PAN3 deadenylation complex catalytic subunit PAN2

1

11

Small-scale

0.479

High

1121051

GLE1
mRNA export factor GLE1

1

3

Small-scale

0.479

High

1137375

GGYF2
GRB10-interacting GYF protein 2

1

9

Small-scale

0.479

High

1137380

NUFP2
FMR1-interacting protein NUFIP2

1

1

Small-scale

0.479

High

1137381

THOC4
THO complex subunit 4

1

8

Small-scale

0.479

High

1137383

DHX37
Probable ATP-dependent RNA helicase DHX37

1

14

Small-scale

0.479

High

1137384

CCAR2
Cell cycle and apoptosis regulator protein 2

1

2

Small-scale

0.479

High

1137386

ATX2L
Ataxin-2-like protein

1

4

Small-scale

0.479

High

1137396

LENG8
Leukocyte receptor cluster member 8

1

2

Small-scale

0.479

High

1137398

CDX2
Homeobox protein CDX-2

1

2

Small-scale

0.479

High

1137400

NOL6
Nucleolar protein 6

1

1

Small-scale

0.479

High

1137401

WDR6
tRNA

1

13

Small-scale

0.479

High

1137406

NXF1
Nuclear RNA export factor 1

1

3

Small-scale

0.479

High

1137408

AGO1
Protein argonaute-1

1

6

Small-scale

0.479

High

1137409

PRP19
Pre-mRNA-processing factor 19

1

6

High-throughput

0.479

High

1137410

CHIP
E3 ubiquitin-protein ligase CHIP

1

6

High-throughput

0.479

High

1137411

PPIE
Peptidyl-prolyl cis-trans isomerase E

1

2

High-throughput

0.479

High

1137413

RBM19
Probable RNA-binding protein 19

1

11

Small-scale

0.479

High

647910

MARK3
MAP/microtubule affinity-regulating kinase 3

1

0

Small-scale

0.458

High

1137377

ZN574
Zinc finger protein 574

1

0

Small-scale

0.458

High

1137390

ESR2
Estrogen receptor beta

1

0

High-throughput

0.458

High

1137402

RT30
Large ribosomal subunit protein mL65

1

0

Small-scale

0.458

High

72805

B4DHC4
14-3-3 protein gamma

1

14

Small-scale

0.445

High

73243

B4E083
Serine/threonine-protein kinase PLK1

1

3

Small-scale

0.445

High

78248

B5MCW2
Large ribosomal subunit protein uL3

1

1

Small-scale

0.445

High

81615

B7Z4B8
Heterogeneous nuclear ribonucleoprotein U like 1

1

7

Small-scale

0.445

High

81652

B7Z7T5
Ubiquitin carboxyl-terminal hydrolase

1

8

Small-scale

0.445

High

90113

D6REM6
Matrin 3

1

4

Small-scale

0.445

High

91326

E5RGV0
Heterogeneous nuclear ribonucleoprotein H1

1

9

Small-scale

0.445

High

91451

E7EQV3
Polyadenylate-binding protein

1

5

Small-scale

0.445

High

92501

E9PIN3
Nuclear RNA export factor 1

1

3

Small-scale

0.445

High

92580

E9PLA9
Cell cycle associated protein 1

1

2

Small-scale

0.445

High

92680

E9PPU1
Ribosomal protein S3

1

2

Small-scale

0.445

High

92689

E9PQD7
Ribosomal protein S2

1

1

Small-scale

0.445

High

134079

DDX3X
ATP-dependent RNA helicase DDX3X

1

8

Small-scale

0.445

High

202197

HNRPR
Heterogeneous nuclear ribonucleoprotein R

1

10

Small-scale

0.445

High

272171

U520
U5 small nuclear ribonucleoprotein 200 kDa helicase

1

11

Small-scale

0.445

High

311562

SMC2
Structural maintenance of chromosomes protein 2

1

7

Small-scale

0.445

High

397414

ADT2
ADP/ATP translocase 2

1

5

Small-scale

0.445

High

400943

RLA0
Large ribosomal subunit protein uL10

1

2

Small-scale

0.445

High

418350

NPM
Nucleophosmin

1

2

Small-scale

0.445

High

444182

RS17
Small ribosomal subunit protein eS17

1

2

Small-scale

0.445

High

453414

ROA1
Heterogeneous nuclear ribonucleoprotein A1

1

9

Small-scale

0.445

High

455537

PARP1
Poly [ADP-ribose] polymerase 1

1

6

Small-scale

0.445

High

486405

RO60
RNA-binding protein RO60

1

1

Small-scale

0.445

High

571485

DDX5
Probable ATP-dependent RNA helicase DDX5

1

8

Small-scale

0.445

High

631182

RS12
Small ribosomal subunit protein eS12

1

1

Small-scale

0.445

High

643525

PTBP1
Polypyrimidine tract-binding protein 1

1

10

Small-scale

0.445

High

646979

1433T
14-3-3 protein theta

1

14

Small-scale

0.445

High

671260

RL12
Large ribosomal subunit protein uL11

1

2

Small-scale

0.445

High

722434

RL22
Large ribosomal subunit protein eL22

1

2

Small-scale

0.445

High

759692

RS19
Small ribosomal subunit protein eS19

1

2

Small-scale

0.445

High

773404

RL13A
Large ribosomal subunit protein uL13

1

1

Small-scale

0.445

High

806889

RS9
Small ribosomal subunit protein uS4

1

1

Small-scale

0.445

High

807175

RS5
Small ribosomal subunit protein uS7

1

2

Small-scale

0.445

High

807394

RS10
Small ribosomal subunit protein eS10

1

1

Small-scale

0.445

High

809328

IQGA1
Ras GTPase-activating-like protein IQGAP1

1

4

Small-scale

0.445

High

846133

RT29
Small ribosomal subunit protein mS29

1

2

Small-scale

0.445

High

875989

ECHB
Trifunctional enzyme subunit beta, mitochondrial

1

2

Small-scale

0.445

High

907960

RS16
Small ribosomal subunit protein uS9

1

4

Small-scale

0.445

High

910860

RS18
Small ribosomal subunit protein uS13

1

1

Small-scale

0.445

High

914997

RS4X
Small ribosomal subunit protein eS4, X isoform

1

1

Small-scale

0.445

High

920785

RS28
Small ribosomal subunit protein eS28

1

1

Small-scale

0.445

High

933846

TBB4B
Tubulin beta-4B chain

1

3

Small-scale

0.445

High

958050

RBM10
RNA-binding protein 10

1

10

Small-scale

0.445

High

981289

SSBP
Single-stranded DNA-binding protein, mitochondrial

1

1

Small-scale

0.445

High

1030288

G3BP1
Ras GTPase-activating protein-binding protein 1

1

9

Small-scale

0.445

High

1057282

SMC1A
Structural maintenance of chromosomes protein 1A

1

8

Small-scale

0.445

High

1137372

DHX57
Putative ATP-dependent RNA helicase DHX57

1

14

Small-scale

0.445

High

1137373

C2D1A
Coiled-coil and C2 domain-containing protein 1A

1

3

Small-scale

0.445

High

1137378

DHX30
ATP-dependent RNA helicase DHX30

1

14

Small-scale

0.445

High

1137385

GEMI5
Gem-associated protein 5

1

6

Small-scale

0.445

High

1137387

RT27
Small ribosomal subunit protein mS27

1

2

Small-scale

0.445

High

1137388

HS105
Heat shock protein 105 kDa

1

8

Small-scale

0.445

High

1137389

RT31
Small ribosomal subunit protein mS31

1

2

Small-scale

0.445

High

1137391

DDX17
Probable ATP-dependent RNA helicase DDX17

1

8

Small-scale

0.445

High

1137392

USP9X
Ubiquitin carboxyl-terminal hydrolase 9X

1

8

Small-scale

0.445

High

1137395

RBM14
RNA-binding protein 14

1

9

Small-scale

0.445

High

1137399

NAT10
RNA cytidine acetyltransferase

1

1

Small-scale

0.445

High

1137403

DDX21
Nucleolar RNA helicase 2

1

12

Small-scale

0.445

High

1137412

SMC3
Structural maintenance of chromosomes protein 3

1

7

Small-scale

0.445

High

147433

SOCS3
Suppressor of cytokine signaling 3

1

2

Small-scale

0.437

High

302169

AP2A2
AP-2 complex subunit alpha-2

1

5

Small-scale

0.437

High

514017

C1TC
C-1-tetrahydrofolate synthase, cytoplasmic

1

2

Small-scale

0.437

High

901881

B2MG
Beta-2-microglobulin [Cleaved into: Beta-2-microglobulin form pI 5.3]

1

7

Small-scale

0.437

High

1137394

AP2M1
AP-2 complex subunit mu

1

4

Small-scale

0.437

High

1137404

ATD3A
ATPase family AAA domain-containing protein 3A

1

6

Small-scale

0.437

High

56783

A2A3R5
40S ribosomal protein S6

1

2

Small-scale

0.407

High

72394

B3KX72
cDNA FLJ44920 fis, clone BRAMY3011501, highly similar to Heterogeneous nuclear ribonucleoprotein U

1

7

Small-scale

0.407

High

72406

B3KY97
cDNA FLJ16235 fis, clone FEBRA2028516

1

1

Small-scale

0.407

High

81622

B7Z4V2
Stress-70 protein, mitochondrial

1

9

Small-scale

0.407

High

87327

C9J9K3
40S ribosomal protein SA

1

2

Small-scale

0.407

High

87577

C9JXB8
Ribosomal protein L24

1

2

Small-scale

0.407

High

90124

D6RG13
Ribosomal protein S3A

1

1

Small-scale

0.407

High

91328

E5RH77
Small ribosomal subunit protein uS11

1

1

Small-scale

0.407

High

92400

E9PD53
Structural maintenance of chromosomes protein

1

7

Small-scale

0.407

High

92444

E9PDU5
tRNA

1

11

Small-scale

0.407

High

92486

E9PH82
Family with sequence similarity 98 member A

1

1

Small-scale

0.407

High

151816

IRS4
Insulin receptor substrate 4

1

1

Small-scale

0.407

High

778176

ECHA
Trifunctional enzyme subunit alpha, mitochondrial

1

2

Small-scale

0.407

High

959232

S25A3
Solute carrier family 25 member 3

1

7

Small-scale

0.407

High

1137397

NUDC1
NudC domain-containing protein 1

1

0

High-throughput

0.232

Low


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Last updated: 15 Jul 2024