Protein: HBS1L
HBS1-like protein (EC 3.6.5.-) (ERFS)

Gene: HBS1L
Organism: Homo sapiens
Interactions: 110
UniProt ID: Q9Y450

Gene Ontology (top 5):
GO:0003746 - translation elongation factor activity
GO:0003924 - GTPase activity
GO:0005525 - GTP binding
GO:0005829 - cytosol
GO:0006412 - translation

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

1310745

PELO
Protein pelota homolog

4

7

High-throughput

0.882

High

1257158

DI3L1
DIS3-like exonuclease 1

4

1

Small-scale

0.699

High

1063787

EXOS7
Exosome complex component RRP42

4

4

Small-scale

0.696

High

1285001

EXOS8
Exosome complex component RRP43

4

4

Small-scale

0.696

High

1377594

EXOS1
Exosome complex component CSL4

4

1

Small-scale

0.696

High

1343617

EXOS3
Exosome complex component RRP40

5

0

Small-scale

0.689

High

1343600

EXOS5
Exosome complex component RRP46

3

5

Small-scale

0.670

High

131626

STK25
Serine/threonine-protein kinase 25

3

3

High-throughput

0.667

High

724291

MSX2
Homeobox protein MSX-2

3

2

High-throughput

0.667

High

986742

EXOS9
Exosome complex component RRP45

3

4

Small-scale

0.660

High

1342633

EXOS4
Exosome complex component RRP41

3

5

Small-scale

0.660

High

1157406

JMJD6
Bifunctional arginine demethylase and lysyl-hydroxylase JMJD6

2

1

High-throughput

0.628

High

1287964

RB39B
Ras-related protein Rab-39B

2

3

High-throughput

0.628

High

1064889

U5S1
116 kDa U5 small nuclear ribonucleoprotein component

1

5

High-throughput

0.618

High

1332808

EGLN3
Prolyl hydroxylase EGLN3

1

1

High-throughput

0.618

High

670891

GFRP
GTP cyclohydrolase 1 feedback regulatory protein

2

0

High-throughput

0.602

High

1238606

EIF1A
Probable RNA-binding protein EIF1AD

2

0

High-throughput

0.602

High

1130070

EXOS6
Exosome complex component MTR3

2

6

Small-scale

0.595

High

1046363

EXOS2
Exosome complex component RRP4

2

0

High-throughput

0.585

High

229149

PRKN
E3 ubiquitin-protein ligase parkin

2

13

High-throughput

0.584

High

1137061

LIN9
Protein lin-9 homolog

2

1

High-throughput

0.574

High

370792

ESR1
Estrogen receptor

2

9

High-throughput

0.571

High

943040

SRPK2
SRSF protein kinase 2

1

8

High-throughput

0.569

High

1302115

SRPK1
SRSF protein kinase 1

1

6

High-throughput

0.569

High

1056170

NBR1
Next to BRCA1 gene 1 protein

2

0

Small-scale

0.559

High

891451

UB2G2
Ubiquitin-conjugating enzyme E2 G2

1

2

High-throughput

0.541

High

243678

DNJA2
DnaJ homolog subfamily A member 2

1

4

High-throughput

0.536

High

325471

AIFM1
Apoptosis-inducing factor 1, mitochondrial

1

2

High-throughput

0.536

High

422647

GPX1
Glutathione peroxidase 1

1

1

High-throughput

0.536

High

515976

PRPS2
Ribose-phosphate pyrophosphokinase 2

1

1

High-throughput

0.536

High

750795

LICH
Lysosomal acid lipase/cholesteryl ester hydrolase

1

1

High-throughput

0.536

High

895762

CXCR4
C-X-C chemokine receptor type 4

1

2

High-throughput

0.536

High

908236

RS16
Small ribosomal subunit protein uS9

1

1

High-throughput

0.536

High

1042910

CUL3
Cullin-3

1

13

High-throughput

0.536

High

1069575

TEBP
Prostaglandin E synthase 3

1

1

High-throughput

0.536

High

1336375

E41L5
Band 4.1-like protein 5

1

1

High-throughput

0.536

High

1347435

HIF1N
Hypoxia-inducible factor 1-alpha inhibitor

1

1

High-throughput

0.536

High

1336625

GOPC
Golgi-associated PDZ and coiled-coil motif-containing protein

1

3

High-throughput

0.515

High

621217

KTHY
Thymidylate kinase

1

0

High-throughput

0.513

High

1136857

FAXC
Failed axon connections homolog

1

0

High-throughput

0.513

High

1156197

CK087
Uncharacterized protein C11orf87

1

0

High-throughput

0.513

High

1198970

ISCA2
Iron-sulfur cluster assembly 2 homolog, mitochondrial

1

0

High-throughput

0.513

High

396110

A4
Amyloid-beta precursor protein

1

2

High-throughput

0.501

High

476620

UBC
Polyubiquitin-C [Cleaved into: Ubiquitin]

1

10

High-throughput

0.501

High

1028456

M3K1
Mitogen-activated protein kinase kinase kinase 1

1

7

Small-scale

0.501

High

1303064

UHRF1
E3 ubiquitin-protein ligase UHRF1

1

5

High-throughput

0.489

High

163514

XPO1
Exportin-1

1

7

High-throughput

0.479

High

237355

IF4E2
Eukaryotic translation initiation factor 4E type 2

1

2

High-throughput

0.479

High

295449

RECQ4
ATP-dependent DNA helicase Q4

1

2

High-throughput

0.479

High

323356

STAU1
Double-stranded RNA-binding protein Staufen homolog 1

1

9

High-throughput

0.479

High

387791

P53
Cellular tumor antigen p53

1

3

High-throughput

0.479

High

434096

LYN
Tyrosine-protein kinase Lyn

1

2

Small-scale

0.479

High

632452

TNR6
Tumor necrosis factor receptor superfamily member 6

1

4

High-throughput

0.479

High

669097

PML
Protein PML

1

4

High-throughput

0.479

High

742626

SYUA
Alpha-synuclein

1

3

High-throughput

0.479

High

780374

CCNF
Cyclin-F

1

3

High-throughput

0.479

High

792121

HD
Huntingtin

1

4

Small-scale

0.479

High

835579

GSK3A
Glycogen synthase kinase-3 alpha

1

6

High-throughput

0.479

High

836112

GSK3B
Glycogen synthase kinase-3 beta

1

8

High-throughput

0.479

High

867025

MOT1
Monocarboxylate transporter 1

1

2

High-throughput

0.479

High

893210

RS20
Small ribosomal subunit protein uS10

1

3

High-throughput

0.479

High

966513

EXOSX
Exosome complex component 10

1

2

High-throughput

0.479

High

999247

EP300
Histone acetyltransferase p300

1

3

High-throughput

0.479

High

1163918

RICTR
Rapamycin-insensitive companion of mTOR

1

1

High-throughput

0.479

High

1168019

GGYF2
GRB10-interacting GYF protein 2

1

1

High-throughput

0.479

High

1254325

BICD2
Protein bicaudal D homolog 2

1

1

High-throughput

0.479

High

1272729

CSN5
COP9 signalosome complex subunit 5

1

11

High-throughput

0.479

High

1326801

WWTR1
WW domain-containing transcription regulator protein 1

1

7

High-throughput

0.479

High

1342860

BRD7
Bromodomain-containing protein 7

1

7

High-throughput

0.479

High

1354979

ZRAN1
Ubiquitin thioesterase ZRANB1

1

4

High-throughput

0.479

High

1377778

ARI1
E3 ubiquitin-protein ligase ARIH1

1

9

High-throughput

0.479

High

1304459

MPH6
M-phase phosphoprotein 6

1

0

High-throughput

0.458

High

1348927

TLS1
Splicing factor C9orf78

1

0

High-throughput

0.458

High

1223637

ULK2
Serine/threonine-protein kinase ULK2

1

4

High-throughput

0.445

High

1303885

CDC5L
Cell division cycle 5-like protein

1

2

High-throughput

0.445

High

348330

MYC
Myc proto-oncogene protein

1

9

High-throughput

0.437

High

352330

INS
Insulin [Cleaved into: Insulin B chain; Insulin A chain]

1

1

High-throughput

0.437

High

385774

NTRK1
High affinity nerve growth factor receptor

1

5

High-throughput

0.437

High

554136

RFA2
Replication protein A 32 kDa subunit

1

5

High-throughput

0.437

High

570222

CEBPB
CCAAT/enhancer-binding protein beta

1

5

High-throughput

0.437

High

652695

RFA1
Replication protein A 70 kDa DNA-binding subunit

1

3

High-throughput

0.437

High

721864

RFA3
Replication protein A 14 kDa subunit

1

3

High-throughput

0.437

High

787039

MTREX
Exosome RNA helicase MTR4

1

3

High-throughput

0.437

High

824576

NR2C2
Nuclear receptor subfamily 2 group C member 2

1

4

High-throughput

0.437

High

1026598

RFA4
Replication protein A 30 kDa subunit

1

5

High-throughput

0.437

High

1172403

TRI67
Tripartite motif-containing protein 67

1

8

High-throughput

0.437

High

1189092

PARPT
Protein mono-ADP-ribosyltransferase TIPARP

1

2

High-throughput

0.437

High

1202489

HOOK3
Protein Hook homolog 3

1

1

High-throughput

0.437

High

1236592

SIR6
NAD-dependent protein deacylase sirtuin-6

1

2

High-throughput

0.437

High

1294177

DDRGK
DDRGK domain-containing protein 1

1

2

High-throughput

0.437

High

1357026

HECD1
E3 ubiquitin-protein ligase HECTD1

1

10

High-throughput

0.437

High

1377779

RBM7
RNA-binding protein 7

1

12

High-throughput

0.437

High

56778

PIPSL
Putative PIP5K1A and PSMD4-like protein

1

2

High-throughput

0.407

High

1039967

SNW1
SNW domain-containing protein 1

1

2

High-throughput

0.407

High

1377780

CCG2
Voltage-dependent calcium channel gamma-2 subunit

3

0

High-throughput

0.347

High

1283778

ISOC2
Isochorismatase domain-containing protein 2

2

0

High-throughput

0.328

High

1357940

LAMP3
Lysosome-associated membrane glycoprotein 3

2

0

High-throughput

0.328

High

64035

SPDE4
Speedy protein E4

1

0

High-throughput

0.279

Low

179284

COPT1
High affinity copper uptake protein 1

1

0

High-throughput

0.279

Low

273319

SURF6
Surfeit locus protein 6

1

0

High-throughput

0.279

Low

672760

CD6
T-cell differentiation antigen CD6

1

0

High-throughput

0.279

Low

1121962

H1BP3
HCLS1-binding protein 3

1

0

High-throughput

0.279

Low

1205653

F90A1
Protein FAM90A1

1

0

High-throughput

0.279

Low

1231878

PIAS4
E3 SUMO-protein ligase PIAS4

1

0

High-throughput

0.279

Low

1238312

F133A
Protein FAM133A

1

0

High-throughput

0.279

Low

1299917

CC85A
Coiled-coil domain-containing protein 85A

1

0

High-throughput

0.279

Low

1312652

MMTA2
Multiple myeloma tumor-associated protein 2

1

0

High-throughput

0.279

Low

262631

TULP3
Tubby-related protein 3

1

0

High-throughput

0.249

Low

1157919

ZCHC8
Zinc finger CCHC domain-containing protein 8

1

0

High-throughput

0.249

Low

1297221

CEP19
Centrosomal protein of 19 kDa

1

0

High-throughput

0.249

Low


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Last updated: 15 Jul 2024