Protein: GROU
Protein groucho (Enhancer of split m9/10 protein) (E(spl)m9/10)

Gene: GROU, gro
Organism: Drosophila melanogaster
Interactions: 87
UniProt ID: P16371

Gene Ontology (top 5):
GO:0000122 - negative regulation of transcription by RNA polymerase II
GO:0003714 - transcription corepressor activity
GO:0005634 - nucleus
GO:0005654 - nucleoplasm
GO:0005667 - transcription regulator complex

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

558355

GROU
Protein groucho

4

17

Small-scale

0.873

High

534341

HAIR
Protein hairy

16

20

Small-scale

0.765

High

525718

ESM7
Enhancer of split m7 protein

10

20

Small-scale

0.754

High

525743

ESM8
Enhancer of split m8 protein

9

20

Small-scale

0.750

High

367240

HMEN
Segmentation polarity homeobox protein engrailed

7

20

Small-scale

0.744

High

558372

ESMD
Enhancer of split mdelta protein

6

20

Small-scale

0.734

High

525705

ESM5
Enhancer of split m5 protein

5

20

Small-scale

0.706

High

558369

ESM3
Enhancer of split m3 protein

5

20

Small-scale

0.706

High

558373

HLES
Protein hairless

5

13

Small-scale

0.705

High

558377

DPN
Protein deadpan

5

20

Small-scale

0.696

High

558410

Q9W0Q1
Homeodomain interacting protein kinase, isoform A

4

17

Small-scale

0.696

High

558413

Q9XTN4
Brinker

4

1

Small-scale

0.690

High

558358

RUNT
Segmentation protein Runt

4

9

Small-scale

0.684

High

558384

PANG2
Protein pangolin, isoform J

4

20

Small-scale

0.680

High

415574

EVE
Segmentation protein even-skipped

3

20

Small-scale

0.648

High

558370

ESMB
Enhancer of split mbeta protein

3

20

Small-scale

0.648

High

558371

ESMC
Enhancer of split mgamma protein

3

20

Small-scale

0.648

High

558402

Q9VN10
Huckebein

3

2

Small-scale

0.648

High

558378

SO
Protein sine oculis

3

20

Small-scale

0.625

High

558385

HDAC1
Histone deacetylase HDAC1

3

20

Small-scale

0.625

High

558360

SLP1
Fork head domain transcription factor slp1

2

20

Small-scale

0.600

High

558409

Q9VWX7
HES-related

2

20

Small-scale

0.600

High

558411

MYC
Myc protein

1

16

Small-scale

0.589

High

499298

KNIR
Zygotic gap protein knirps

1

20

Small-scale

0.586

High

220622

CTBP
C-terminal-binding protein

2

9

Small-scale

0.584

High

558357

VND
Homeobox protein vnd

2

20

Small-scale

0.584

High

558381

Q7KUL4
Intermediate neuroblasts defective

2

18

Small-scale

0.584

High

558368

PANG1
Protein pangolin, isoforms A/H/I/S

2

20

Small-scale

0.563

High

558365

GSC
Homeobox protein goosecoid

2

20

High-throughput

0.560

High

547606

DORS
Embryonic polarity protein dorsal

2

6

Small-scale

0.552

High

558392

CIC
Putative transcription factor capicua

2

20

Small-scale

0.552

High

436853

KRH1
Krueppel homolog 1

1

1

High-throughput

0.541

High

558359

ETS3
DNA-binding protein D-ETS-3

1

17

High-throughput

0.541

High

558361

FTZF1
Nuclear hormone receptor FTZ-F1

1

20

High-throughput

0.541

High

558362

SALM
Homeotic protein spalt-major

1

11

High-throughput

0.541

High

558364

E78C
Ecdysone-induced protein 78C

1

20

High-throughput

0.541

High

558375

DICH
SOX domain-containing protein dichaete

1

20

High-throughput

0.541

High

558383

TAD2B
Transcriptional adapter 2B

1

8

High-throughput

0.541

High

558393

TIPT
Protein tiptop

1

1

High-throughput

0.541

High

558395

Q9VAY8
LD18667p

1

2

High-throughput

0.541

High

558405

BOWEL
Protein bowel

1

2

High-throughput

0.541

High

558374

Q0E8K8
FI21816p1

1

8

High-throughput

0.536

High

558363

PEP
Zinc finger protein on ecdysone puffs

1

0

High-throughput

0.518

High

558407

Q9VTE8
GEO08928p1

1

0

High-throughput

0.518

High

332491

O97102
Small ubiquitin-related modifier

1

2

Small-scale

0.515

High

284748

UNC4
Homeobox protein unc-4

1

20

High-throughput

0.508

High

403512

HMIN
Homeobox protein invected

1

20

High-throughput

0.508

High

484925

HMH2
Homeobox protein H2.0

1

20

High-throughput

0.508

High

558396

Q9VDA2
Ladybird late, isoform A

1

20

High-throughput

0.508

High

356066

H3
Histone H3

2

11

Small-scale

0.504

High

558380

Q7KNM2
Dorsal interacting protein 4

1

12

High-throughput

0.492

High

332597

O97111
LD29223p

1

0

High-throughput

0.486

High

90931

E1JJ76
Alhambra, isoform H

1

15

High-throughput

0.481

High

558366

UBX
Homeotic protein ultrabithorax

1

20

High-throughput

0.481

High

558379

Q5U156
RE01954p

1

8

High-throughput

0.481

High

558414

Q9XYM5
LD27861p

1

7

High-throughput

0.481

High

53129

A1Z8F4
Schnurri, isoform D

1

4

Small-scale

0.479

High

185801

PAX6
Paired box protein Pax-6

1

20

Small-scale

0.479

High

485920

AST4
Achaete-scute complex protein T4

1

5

Small-scale

0.479

High

558382

Q7KVG9
Chip, isoform B

1

1

Small-scale

0.479

High

558386

OPTIX
Protein Optix

1

20

Small-scale

0.479

High

558389

Q9GRA9
Master of thick veins

1

19

Small-scale

0.479

High

558390

Q9N693
Brakeless-B

1

20

Small-scale

0.479

High

558391

Q9NHP8
GTX/Nkx6B-like homeodomain protein

1

20

Small-scale

0.479

High

558394

ASF1
Histone chaperone asf1

1

1

Small-scale

0.479

High

558399

Q9VJ16
GH26014p

1

20

Small-scale

0.479

High

558400

ELBOW
Zinc finger protein Elbow

1

7

Small-scale

0.479

High

558401

Q9VMR2
LP04777p

1

20

Small-scale

0.479

High

525696

ESM4
Enhancer of split m4 protein

1

0

Small-scale

0.460

High

355223

H1
Histone H1

1

0

Small-scale

0.458

High

2350

A0A0B4KER0
Relative of woc, isoform C

1

8

High-throughput

0.457

High

2376

A0A0B4KGP1
Alhambra, isoform P

1

12

High-throughput

0.457

High

52653

A1Z7P5
Suppressor of variegation 2-10, isoform I

1

7

High-throughput

0.457

High

558388

Q961V5
GH04704p

1

20

High-throughput

0.457

High

116435

M9PIW5
Uncharacterized protein, isoform B

1

1

High-throughput

0.439

High

558403

Q9VN42
Dorsal interacting protein 2

1

1

Small-scale

0.439

High

558367

H4
Histone H4

1

8

Small-scale

0.437

High

558412

Q9W4U0
Uncharacterized protein, isoform A

1

1

High-throughput

0.417

High

558356

TIN
Muscle-specific homeobox protein tinman

1

20

High-throughput

0.381

High

558376

DRI
Protein dead ringer

1

11

High-throughput

0.381

High

558387

Q960G9
SD02279p

1

1

High-throughput

0.348

High

558408

Q9VWX6
Holes in muscle

2

0

Small-scale

0.305

High

558397

Q9VFM2
FI08034p

1

0

High-throughput

0.265

Low

558398

Q9VGM5
IP07109p

1

0

High-throughput

0.265

Low

558404

Q9VPF9
SD10847p

1

0

High-throughput

0.265

Low

558406

Q9VT66
GEO02549p1

1

0

High-throughput

0.265

Low


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Last updated: 15 Jul 2024