Protein: PRIO
Major prion protein (PrP) (PrP27-30) (PrP33-35C) (CD antigen CD230)

Gene: PRIO, Prnp
Organism: Mus musculus
Interactions: 59
UniProt ID: P04925

Gene Ontology (top 5):
GO:0001540 - amyloid-beta binding
GO:0001933 - negative regulation of protein phosphorylation
GO:0002020 - protease binding
GO:0005507 - copper ion binding
GO:0005521 - lamin binding

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

392749

PRIO
Major prion protein

7

4

Small-scale

0.969

High

392755

A4
Amyloid-beta precursor protein

4

3

Small-scale

0.689

High

392776

MOG
Myelin-oligodendrocyte glycoprotein

1

1

Small-scale

0.665

High

392775

GRB2
Growth factor receptor-bound protein 2

2

1

Small-scale

0.621

High

392792

NECT1
Nectin-1

1

8

Small-scale

0.618

High

392797

DPP6
Dipeptidyl aminopeptidase-like protein 6

2

1

Small-scale

0.601

High

392786

IGSF8
Immunoglobulin superfamily member 8

1

0

Small-scale

0.586

High

392793

PRND
Prion-like protein doppel

1

0

Small-scale

0.586

High

392789

CADM3
Cell adhesion molecule 3

1

5

Small-scale

0.553

High

392773

SHAN3
SH3 and multiple ankyrin repeat domains protein 3

1

1

High-throughput

0.536

High

192272

NCAM2
Neural cell adhesion molecule 2

1

5

Small-scale

0.515

High

392751

PDIA1
Protein disulfide-isomerase

1

1

Small-scale

0.515

High

392756

CNTN1
Contactin-1

1

3

Small-scale

0.515

High

392757

NCAM1
Neural cell adhesion molecule 1

1

3

Small-scale

0.515

High

392760

MAG
Myelin-associated glycoprotein

1

7

Small-scale

0.515

High

392770

APLP2
Amyloid beta precursor like protein 2

1

3

Small-scale

0.515

High

392781

LSAMP
Limbic system-associated membrane protein

1

8

Small-scale

0.515

High

392791

CSTN1
Calsyntenin-1

1

1

Small-scale

0.515

High

392750

APOE
Apolipoprotein E

1

0

Small-scale

0.493

High

392759

BIP
Endoplasmic reticulum chaperone BiP

1

0

Small-scale

0.493

High

392761

DYN1
Dynamin-1

1

0

Small-scale

0.493

High

392771

CLUS
Clusterin

1

0

Small-scale

0.493

High

392794

APBB1
Amyloid beta precursor protein binding family B member 1

1

0

Small-scale

0.493

High

57058

A2AFG8
L1 cell adhesion molecule

1

3

Small-scale

0.479

High

103587

G5E8G3
Opioid binding protein/cell adhesion molecule-like

1

6

Small-scale

0.479

High

139076

DPYL2
Dihydropyrimidinase-related protein 2

1

1

Small-scale

0.479

High

292460

SYN1
Synapsin-1

1

3

Small-scale

0.479

High

381378

MBP
Myelin basic protein

1

1

Small-scale

0.479

High

392753

TAU
Microtubule-associated protein tau

1

4

High-throughput

0.479

High

392754

L1CAM
Neural cell adhesion molecule L1

1

3

Small-scale

0.479

High

392758

AT1B1
Sodium/potassium-transporting ATPase subunit beta-1

1

1

Small-scale

0.479

High

392763

MYPR
Myelin proteolipid protein

1

2

Small-scale

0.479

High

392765

GBB1
Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1

1

1

Small-scale

0.479

High

392766

1433Z
14-3-3 protein zeta/delta

1

1

Small-scale

0.479

High

392769

APLP1
Amyloid beta precursor like protein 1

1

3

Small-scale

0.479

High

392778

AT1A3
Sodium/potassium-transporting ATPase subunit alpha-3

1

4

Small-scale

0.479

High

392779

TAOK2
Serine/threonine-protein kinase TAO2

1

1

High-throughput

0.479

High

392780

Q8BG33
Neurotrimin

1

8

Small-scale

0.479

High

392787

AT1A1
Sodium/potassium-transporting ATPase subunit alpha-1

1

4

Small-scale

0.479

High

392790

NTRI
Neurotrimin

1

7

Small-scale

0.479

High

392795

AT2B2
Plasma membrane calcium-transporting ATPase 2

1

5

Small-scale

0.479

High

139013

CA2D1
Voltage-dependent calcium channel subunit alpha-2/delta-1

1

0

Small-scale

0.458

High

139532

STXB1
Syntaxin-binding protein 1

1

0

Small-scale

0.458

High

392764

1433E
14-3-3 protein epsilon

1

0

Small-scale

0.458

High

392767

TRAF6
TNF receptor-associated factor 6

1

0

Small-scale

0.458

High

392772

GRM5
Metabotropic glutamate receptor 5

1

0

Small-scale

0.458

High

392777

UBP7
Ubiquitin carboxyl-terminal hydrolase 7

1

0

High-throughput

0.458

High

392783

ERI3
ERI1 exoribonuclease 3

1

0

Small-scale

0.458

High

392784

PDE10
cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A

1

0

Small-scale

0.458

High

392785

FNDC5
Fibronectin type III domain-containing protein 5

1

0

High-throughput

0.458

High

392752

BCL2
Apoptosis regulator Bcl-2

1

0

Small-scale

0.438

High

392782

Q8BMT5
Ig-like domain-containing protein

1

6

Small-scale

0.437

High

392768

SPRL1
SPARC-like protein 1

1

0

Small-scale

0.269

Low

392796

ADA23
Disintegrin and metalloproteinase domain-containing protein 23

1

0

Small-scale

0.269

Low

371479

CFAD
Complement factor D

1

0

High-throughput

0.249

Low

392762

PRS7
26S proteasome regulatory subunit 7

1

0

Small-scale

0.249

Low

392774

CYFP2
Cytoplasmic FMR1-interacting protein 2

1

0

High-throughput

0.249

Low

392788

PSMD6
26S proteasome non-ATPase regulatory subunit 6

1

0

Small-scale

0.249

Low


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Last updated: 15 Jul 2024