Protein: SMUF1
E3 ubiquitin-protein ligase Smurf1 (EC 2.3.2.26) (HECT-type E3 ubiquitin transferase Smurf1) (Lethal with a checkpoint kinase protein) (SMAD ubiquitination regulatory factor 1 homolog) (DSmurf)

Gene: SMUF1, Smurf
Organism: Drosophila melanogaster
Interactions: 24
UniProt ID: Q9V853

Gene Ontology (top 5):
GO:0000151 - ubiquitin ligase complex
GO:0001700 - embryonic development via the syncytial blastoderm
GO:0004842 - ubiquitin-protein transferase activity
GO:0005737 - cytoplasm
GO:0005829 - cytosol

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

615093

PTC
Protein patched

2

14

Small-scale

0.620

High

1466458

SMUF1
E3 ubiquitin-protein ligase Smurf1

1

18

Small-scale

0.618

High

1466459

WARTS
Serine/threonine-protein kinase Warts

2

20

Small-scale

0.584

High

1377996

Q95SI0
receptor protein serine/threonine kinase

1

19

Small-scale

0.578

High

57055

A1ZAN6
Rho guanine nucleotide exchange factor 2, isoform D

1

7

High-throughput

0.575

High

837159

MAD
Protein mothers against dpp

2

20

High-throughput

0.560

High

661867

FUSED
Serine/threonine-protein kinase fused

1

17

Small-scale

0.536

High

1344656

Q8SYU5
RE33762p

1

20

High-throughput

0.536

High

1466460

Q9VGU4
FI02822p

1

20

High-throughput

0.536

High

1019403

SMO
Protein smoothened

2

2

Small-scale

0.533

High

746392

GPRK2
G protein-coupled receptor kinase 2

1

20

Small-scale

0.479

High

1466464

Q9VVJ5
Nedd4 family interacting protein

1

17

Small-scale

0.479

High

119022

M9NFI9
Neurabin-1

1

12

High-throughput

0.445

High

262945

TENM
Teneurin-m

1

13

High-throughput

0.445

High

614143

SGG
Protein kinase shaggy

1

3

High-throughput

0.445

High

756946

FAS2
Fasciclin-2

1

5

High-throughput

0.445

High

1466465

Q9VX92
Rho GTPase activating protein at 15B, isoform C

1

7

High-throughput

0.445

High

1466462

Q9VQW7
Echinoid, isoform A

1

1

Small-scale

0.437

High

57964

A1ZBB1
Galectin

1

3

High-throughput

0.407

High

1175076

NETB
Netrin-B

1

3

High-throughput

0.407

High

1466463

Q9VV52
LD37257p

1

11

High-throughput

0.407

High

1377844

PITA
Zinc finger protein pita

1

0

High-throughput

0.232

Low

1466461

Q9VLB2
IP09645p

1

0

High-throughput

0.232

Low


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Last updated: 11Aug2025