Protein: CMTD1
Catechol O-methyltransferase domain-containing protein 1 (EC 2.1.1.-)

Gene: CMTD1, COMTD1
Organism: Homo sapiens
Interactions: 196
UniProt ID: Q86VU5

Gene Ontology (top 5):
GO:0008171 - O-methyltransferase activity
GO:0008757 - S-adenosylmethionine-dependent methyltransferase activity
GO:0016020 - membrane
GO:0032259 - methylation

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

312317

IPO7
Importin-7

3

8

High-throughput

0.667

High

867729

SYRC
Arginine--tRNA ligase, cytoplasmic

3

1

High-throughput

0.667

High

1159144

ANM9
Protein arginine N-methyltransferase 9

3

1

High-throughput

0.667

High

1202512

GEMI5
Gem-associated protein 5

3

1

High-throughput

0.667

High

1202534

IPO9
Importin-9

3

9

High-throughput

0.667

High

777210

PEX19
Peroxisomal biogenesis factor 19

3

0

High-throughput

0.638

High

783071

SYIC
Isoleucine--tRNA ligase, cytoplasmic

3

0

High-throughput

0.638

High

1202503

STAG2
Cohesin subunit SA-2

3

0

High-throughput

0.638

High

1202524

PBIP1
Pre-B-cell leukemia transcription factor-interacting protein 1

3

0

High-throughput

0.638

High

1202580

COG5
Conserved oligomeric Golgi complex subunit 5

3

0

High-throughput

0.638

High

1060813

IMB1
Importin subunit beta-1

2

5

High-throughput

0.628

High

431001

SYEP
Bifunctional glutamate/proline--tRNA ligase

2

2

High-throughput

0.611

High

541389

SYDC
Aspartate--tRNA ligase, cytoplasmic

2

1

High-throughput

0.611

High

834784

RBP2
E3 SUMO-protein ligase RanBP2

2

1

High-throughput

0.611

High

203384

IF4G3
Eukaryotic translation initiation factor 4 gamma 3

3

2

High-throughput

0.609

High

549908

PHKG2
Phosphorylase b kinase gamma catalytic chain, liver/testis isoform

3

1

High-throughput

0.609

High

1120000

PDCD4
Programmed cell death protein 4

3

1

High-throughput

0.609

High

1129239

P4R3B
Serine/threonine-protein phosphatase 4 regulatory subunit 3B

3

1

High-throughput

0.609

High

1202420

HOOK3
Protein Hook homolog 3

3

1

High-throughput

0.609

High

1202499

S11IP
Serine/threonine-protein kinase 11-interacting protein

3

1

High-throughput

0.609

High

1202511

CIP2A
Protein CIP2A

3

1

High-throughput

0.609

High

1202539

RGPD5
RANBP2-like and GRIP domain-containing protein 5/6

3

1

High-throughput

0.609

High

1202548

XPO4
Exportin-4

3

4

High-throughput

0.609

High

1202574

IPO11
Importin-11

3

8

High-throughput

0.609

High

1202586

TNPO3
Transportin-3

3

8

High-throughput

0.609

High

155596

TNPO2
Transportin-2

3

8

High-throughput

0.599

High

1019421

AIMP1
Aminoacyl tRNA synthase complex-interacting multifunctional protein 1

2

0

High-throughput

0.585

High

1202571

DDX20
Probable ATP-dependent RNA helicase DDX20

2

0

High-throughput

0.585

High

858007

NUP98
Nuclear pore complex protein Nup98-Nup96

2

1

High-throughput

0.558

High

1025648

EI2BE
Translation initiation factor eIF2B subunit epsilon

2

3

High-throughput

0.558

High

1202509

NUP37
Nucleoporin Nup37

2

1

High-throughput

0.558

High

369931

ESR1
Estrogen receptor

2

0

High-throughput

0.547

High

162943

XPO1
Exportin-1

1

9

High-throughput

0.536

High

321294

TBCD8
TBC1 domain family member 8

1

1

High-throughput

0.536

High

787516

MTOR
Serine/threonine-protein kinase mTOR

1

1

High-throughput

0.536

High

789301

CNDD3
Condensin-2 complex subunit D3

1

1

High-throughput

0.536

High

842005

LRBA
Lipopolysaccharide-responsive and beige-like anchor protein

1

2

High-throughput

0.536

High

874537

XPO2
Exportin-2

1

7

High-throughput

0.536

High

880137

SYMC
Methionine--tRNA ligase, cytoplasmic

1

1

High-throughput

0.536

High

1047767

CKAP5
Cytoskeleton-associated protein 5

1

3

High-throughput

0.536

High

1051819

EI2BA
Translation initiation factor eIF2B subunit alpha

1

2

High-throughput

0.536

High

1063338

CND1
Condensin complex subunit 1

1

1

High-throughput

0.536

High

1065479

S39AE
Metal cation symporter ZIP14

1

6

High-throughput

0.536

High

1146062

TBC9B
TBC1 domain family member 9B

1

2

High-throughput

0.536

High

1198612

SYVN1
E3 ubiquitin-protein ligase synoviolin

1

2

High-throughput

0.536

High

1201970

CAND1
Cullin-associated NEDD8-dissociated protein 1

1

7

High-throughput

0.536

High

1202500

S39AB
Zinc transporter ZIP11

1

6

High-throughput

0.536

High

1202513

IPO4
Importin-4

1

6

High-throughput

0.536

High

1202518

GCN1
Stalled ribosome sensor GCN1

1

5

High-throughput

0.536

High

1202519

NU205
Nuclear pore complex protein Nup205

1

1

High-throughput

0.536

High

1202532

EXOC2
Exocyst complex component 2

1

1

High-throughput

0.536

High

1202579

UBQL1
Ubiquilin-1

1

1

High-throughput

0.523

High

170882

PGRC2
Membrane-associated progesterone receptor component 2

1

0

High-throughput

0.513

High

199352

ZW10
Centromere/kinetochore protein zw10 homolog

1

0

High-throughput

0.513

High

213226

SNG2
Synaptogyrin-2

1

0

High-throughput

0.513

High

234346

GSDME
Gasdermin-E

1

0

High-throughput

0.513

High

240765

USO1
General vesicular transport factor p115

1

0

High-throughput

0.513

High

298628

UFL1
E3 UFM1-protein ligase 1

1

0

High-throughput

0.513

High

792204

ECE1
Endothelin-converting enzyme 1

1

0

High-throughput

0.513

High

884029

GEMI4
Gem-associated protein 4

1

0

High-throughput

0.513

High

884753

NU107
Nuclear pore complex protein Nup107

1

0

High-throughput

0.513

High

1131237

NU188
Nucleoporin NUP188

1

0

High-throughput

0.513

High

1152345

CNDH2
Condensin-2 complex subunit H2

1

0

High-throughput

0.513

High

1162188

BRAT1
BRCA1-associated ATM activator 1

1

0

High-throughput

0.513

High

1186172

DYM
Dymeclin

1

0

High-throughput

0.513

High

1202495

CNDG2
Condensin-2 complex subunit G2

1

0

High-throughput

0.513

High

1202498

K2013
Uncharacterized protein KIAA2013

1

0

High-throughput

0.513

High

1202501

INT1
Integrator complex subunit 1

1

0

High-throughput

0.513

High

1202515

NU133
Nuclear pore complex protein Nup133

1

0

High-throughput

0.513

High

1202517

GBF1
Golgi-specific brefeldin A-resistance guanine nucleotide exchange factor 1

1

0

High-throughput

0.513

High

1202523

EXOC4
Exocyst complex component 4

1

0

High-throughput

0.513

High

1202528

CYFP2
Cytoplasmic FMR1-interacting protein 2

1

0

High-throughput

0.513

High

1202531

CK5P3
CDK5 regulatory subunit-associated protein 3

1

0

High-throughput

0.513

High

1202533

COG8
Conserved oligomeric Golgi complex subunit 8

1

0

High-throughput

0.513

High

1202537

CLCC1
Chloride channel CLIC-like protein 1

1

0

High-throughput

0.513

High

1202538

MMS19
MMS19 nucleotide excision repair protein homolog

1

0

High-throughput

0.513

High

1202546

NUP85
Nuclear pore complex protein Nup85

1

0

High-throughput

0.513

High

1202550

INT2
Integrator complex subunit 2

1

0

High-throughput

0.513

High

1202552

HEAT1
HEAT repeat-containing protein 1

1

0

High-throughput

0.513

High

1202564

CKLF6
CKLF-like MARVEL transmembrane domain-containing protein 6

1

0

High-throughput

0.513

High

1202566

ATX10
Ataxin-10

1

0

High-throughput

0.513

High

1202567

NCDN
Neurochondrin

1

0

High-throughput

0.513

High

1202582

EXOC7
Exocyst complex component 7

1

0

High-throughput

0.513

High

58236

SYTC2
Threonine--tRNA ligase 2, cytoplasmic

1

1

High-throughput

0.489

High

178208

IPO8
Importin-8

1

8

High-throughput

0.489

High

207959

XPOT
Exportin-T

1

7

High-throughput

0.489

High

236435

RNBP6
Ran-binding protein 6

1

5

High-throughput

0.489

High

282949

CIAO1
Probable cytosolic iron-sulfur protein assembly protein CIAO1

1

1

High-throughput

0.489

High

295813

ST17B
Serine/threonine-protein kinase 17B

1

1

High-throughput

0.489

High

310704

VAPB
Vesicle-associated membrane protein-associated protein B/C

1

1

High-throughput

0.489

High

311578

SMC2
Structural maintenance of chromosomes protein 2

1

1

High-throughput

0.489

High

714672

CNR2
Cannabinoid receptor 2

1

2

Small-scale

0.489

High

814488

SYQ
Glutamine--tRNA ligase

1

1

High-throughput

0.489

High

834427

EI2BB
Translation initiation factor eIF2B subunit beta

1

2

High-throughput

0.489

High

997407

VAC14
Protein VAC14 homolog

1

7

High-throughput

0.489

High

1065540

SYK
Lysine--tRNA ligase

1

1

High-throughput

0.489

High

1153034

P4R3A
Serine/threonine-protein phosphatase 4 regulatory subunit 3A

1

1

High-throughput

0.489

High

1160132

S39A4
Zinc transporter ZIP4

1

6

High-throughput

0.489

High

1174996

TBA1A
Tubulin alpha-1A chain

1

1

High-throughput

0.489

High

1202505

CCYL1
Cyclin-Y-like protein 1

1

1

High-throughput

0.489

High

1202507

CCNY
Cyclin-Y

1

1

High-throughput

0.489

High

1202510

TBC15
TBC1 domain family member 15

1

3

High-throughput

0.489

High

1202521

TNPO1
Transportin-1

1

7

High-throughput

0.489

High

1202526

HOOK2
Protein Hook homolog 2

1

1

High-throughput

0.489

High

1202542

TBA1C
Tubulin alpha-1C chain

1

1

High-throughput

0.489

High

1202556

XPO5
Exportin-5

1

6

High-throughput

0.489

High

1202557

EI2BG
Translation initiation factor eIF2B subunit gamma

1

1

High-throughput

0.489

High

1202562

SMC4
Structural maintenance of chromosomes protein 4

1

1

High-throughput

0.489

High

1202573

EI2BD
Translation initiation factor eIF2B subunit delta

1

2

High-throughput

0.489

High

1202576

XPO7
Exportin-7

1

6

High-throughput

0.489

High

1202578

S39AA
Zinc transporter ZIP10

1

6

High-throughput

0.489

High

1202581

PP6R1
Serine/threonine-protein phosphatase 6 regulatory subunit 1

1

1

High-throughput

0.489

High

1183792

5MP2
eIF5-mimic protein 2

1

2

High-throughput

0.479

High

1202520

AKAP1
A-kinase anchor protein 1, mitochondrial

1

0

High-throughput

0.458

High

258477

COQ9
Ubiquinone biosynthesis protein COQ9, mitochondrial

1

1

High-throughput

0.437

High

1034229

S39A6
Zinc transporter ZIP6

1

6

High-throughput

0.437

High

1202551

PKHA4
Pleckstrin homology domain-containing family A member 4

1

1

High-throughput

0.437

High

1202570

ZRAN1
Ubiquitin thioesterase ZRANB1

1

2

High-throughput

0.437

High

1117732

Q4LE60
TNPO2 variant protein

1

8

High-throughput

0.407

High

129130

IFRD1
Interferon-related developmental regulator 1

3

0

High-throughput

0.347

High

157747

GEMI2
Gem-associated protein 2

3

0

High-throughput

0.347

High

236793

CCNT1
Cyclin-T1

3

0

High-throughput

0.347

High

255334

HIP1R
Huntingtin-interacting protein 1-related protein

3

0

High-throughput

0.347

High

801545

KPB1
Phosphorylase b kinase regulatory subunit alpha, skeletal muscle isoform

3

0

High-throughput

0.347

High

1148303

INT3
Integrator complex subunit 3

3

0

High-throughput

0.347

High

1188025

SETX
Probable helicase senataxin

3

0

High-throughput

0.347

High

1190541

HEAT3
HEAT repeat-containing protein 3

3

0

High-throughput

0.347

High

1191041

WAPL
Wings apart-like protein homolog

3

0

High-throughput

0.347

High

1202497

SUGP1
SURP and G-patch domain-containing protein 1

3

0

High-throughput

0.347

High

1202506

MIGA1
Mitoguardin 1

3

0

High-throughput

0.347

High

1202536

UBP28
Ubiquitin carboxyl-terminal hydrolase 28

3

0

High-throughput

0.347

High

1202540

HAUS7
HAUS augmin-like complex subunit 7

3

0

High-throughput

0.347

High

1202545

MSTO1
Protein misato homolog 1

3

0

High-throughput

0.347

High

1202558

PNO1
RNA-binding protein PNO1

3

0

High-throughput

0.347

High

1202559

SOSSC
SOSS complex subunit C

3

0

High-throughput

0.347

High

1202561

DIAP3
Protein diaphanous homolog 3

3

0

High-throughput

0.347

High

1202568

TFP11
Tuftelin-interacting protein 11

3

0

High-throughput

0.347

High

229697

JIP4
C-Jun-amino-terminal kinase-interacting protein 4

2

0

High-throughput

0.328

High

674953

PUR8
Adenylosuccinate lyase

2

0

High-throughput

0.318

High

1058862

COG2
Conserved oligomeric Golgi complex subunit 2

2

0

High-throughput

0.318

High

1202496

DAAF5
Dynein axonemal assembly factor 5

2

0

High-throughput

0.318

High

1202527

SAAL1
Protein SAAL1

2

0

High-throughput

0.318

High

131922

UPK2
Uroplakin-2

1

0

High-throughput

0.279

Low

135461

PPP6
Serine/threonine-protein phosphatase 6 catalytic subunit

1

0

High-throughput

0.279

Low

163618

BTAF1
TATA-binding protein-associated factor 172

1

0

High-throughput

0.279

Low

166961

ANR28
Serine/threonine-protein phosphatase 6 regulatory ankyrin repeat subunit A

1

0

High-throughput

0.279

Low

168186

PLCB
1-acyl-sn-glycerol-3-phosphate acyltransferase beta

1

0

High-throughput

0.279

Low

195920

TTI1
TELO2-interacting protein 1 homolog

1

0

High-throughput

0.279

Low

236952

BUB1B
Mitotic checkpoint serine/threonine-protein kinase BUB1 beta

1

0

High-throughput

0.279

Low

299570

LRIG2
Leucine-rich repeats and immunoglobulin-like domains protein 2

1

0

High-throughput

0.279

Low

313080

AGM1
Phosphoacetylglucosamine mutase

1

0

High-throughput

0.279

Low

335682

COX1
Cytochrome c oxidase subunit 1

1

0

High-throughput

0.279

Low

841509

KNTC1
Kinetochore-associated protein 1

1

0

High-throughput

0.279

Low

849558

GPM6A
Neuronal membrane glycoprotein M6-a

1

0

High-throughput

0.279

Low

949228

COG7
Conserved oligomeric Golgi complex subunit 7

1

0

High-throughput

0.279

Low

1015911

NU160
Nuclear pore complex protein Nup160

1

0

High-throughput

0.279

Low

1047944

KCC1A
Calcium/calmodulin-dependent protein kinase type 1

1

0

High-throughput

0.279

Low

1084077

OCLN
Occludin

1

0

High-throughput

0.279

Low

1084826

SMN
Survival motor neuron protein

1

0

High-throughput

0.279

Low

1100525

PDS5A
Sister chromatid cohesion protein PDS5 homolog A

1

0

High-throughput

0.279

Low

1109557

TKFC
Triokinase/FMN cyclase

1

0

High-throughput

0.279

Low

1162896

ZNT9
Proton-coupled zinc antiporter SLC30A9, mitochondrial

1

0

High-throughput

0.279

Low

1168061

THADA
tRNA

1

0

High-throughput

0.279

Low

1200083

NLRX1
NLR family member X1

1

0

High-throughput

0.279

Low

1202494

LIPB1
Liprin-beta-1

1

0

High-throughput

0.279

Low

1202502

VPS8
Vacuolar protein sorting-associated protein 8 homolog

1

0

High-throughput

0.279

Low

1202504

FXL16
F-box/LRR-repeat protein 16

1

0

High-throughput

0.279

Low

1202508

DIK2A
Divergent protein kinase domain 2A

1

0

High-throughput

0.279

Low

1202514

COG1
Conserved oligomeric Golgi complex subunit 1

1

0

High-throughput

0.279

Low

1202516

GEMI6
Gem-associated protein 6

1

0

High-throughput

0.279

Low

1202522

FAKD4
FAST kinase domain-containing protein 4

1

0

High-throughput

0.279

Low

1202525

INT12
Integrator complex subunit 12

1

0

High-throughput

0.279

Low

1202529

INT4
Integrator complex subunit 4

1

0

High-throughput

0.279

Low

1202530

COG3
Conserved oligomeric Golgi complex subunit 3

1

0

High-throughput

0.279

Low

1202535

XPO6
Exportin-6

1

0

High-throughput

0.279

Low

1202541

SOSB1
SOSS complex subunit B1

1

0

High-throughput

0.279

Low

1202543

ZNG1A
Zinc-regulated GTPase metalloprotein activator 1A

1

0

High-throughput

0.279

Low

1202544

LRRC1
Leucine-rich repeat-containing protein 1

1

0

High-throughput

0.279

Low

1202547

FACD2
Fanconi anemia group D2 protein

1

0

High-throughput

0.279

Low

1202549

TTYH3
Protein tweety homolog 3

1

0

High-throughput

0.279

Low

1202553

PHAX
Phosphorylated adapter RNA export protein

1

0

High-throughput

0.279

Low

1202554

COG4
Conserved oligomeric Golgi complex subunit 4

1

0

High-throughput

0.279

Low

1202560

FIRRM
FIGNL1-interacting regulator of recombination and mitosis

1

0

High-throughput

0.279

Low

1202563

GEMI8
Gem-associated protein 8

1

0

High-throughput

0.279

Low

1202569

FA8A1
Protein FAM8A1

1

0

High-throughput

0.279

Low

1202572

GPN3
GPN-loop GTPase 3

1

0

High-throughput

0.279

Low

1202575

MD2L2
Mitotic spindle assembly checkpoint protein MAD2B

1

0

High-throughput

0.279

Low

1202577

VPS28
Vacuolar protein sorting-associated protein 28 homolog

1

0

High-throughput

0.279

Low

1202583

COG6
Conserved oligomeric Golgi complex subunit 6

1

0

High-throughput

0.279

Low

1202584

CAB39
Calcium-binding protein 39

1

0

High-throughput

0.279

Low

1202585

CIA2B
Cytosolic iron-sulfur assembly component 2B

1

0

High-throughput

0.279

Low

1173175

PAXI1
PAX-interacting protein 1

1

0

High-throughput

0.251

Low

1202555

RENT2
Regulator of nonsense transcripts 2

1

0

High-throughput

0.251

Low

177929

TMPS2
Transmembrane protease serine 2

1

0

High-throughput

0.249

Low

352165

INS
Insulin [Cleaved into: Insulin B chain; Insulin A chain]

1

0

High-throughput

0.249

Low

1202565

PP4R2
Serine/threonine-protein phosphatase 4 regulatory subunit 2

1

0

High-throughput

0.249

Low


Service provided by Combinatics, Japan

Last updated: 15 Jul 2024