Protein: HXB5
Homeobox protein Hox-B5 (Homeobox protein HHO.C10) (Homeobox protein Hox-2A) (Homeobox protein Hu-1)

Gene: HXB5, HOXB5
Organism: Homo sapiens
Interactions: 112
UniProt ID: P09067

Gene Ontology (top 5):
GO:0000785 - chromatin
GO:0000978 - RNA polymerase II cis-regulatory region sequence-specific DNA binding
GO:0000981 - DNA-binding transcription factor activity, RNA polymerase II-specific
GO:0001228 - DNA-binding transcription activator activity, RNA polymerase II-specific
GO:0001650 - fibrillar center

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

446885

HXC4
Homeobox protein Hox-C4

3

19

High-throughput

0.861

High

447226

PBX1
Pre-B-cell leukemia transcription factor 1

2

20

High-throughput

0.783

High

447227

PBX2
Pre-B-cell leukemia transcription factor 2

2

20

High-throughput

0.783

High

447287

PBX4
Pre-B-cell leukemia transcription factor 4

2

20

High-throughput

0.783

High

447225

TRI23
E3 ubiquitin-protein ligase TRIM23

3

7

High-throughput

0.675

High

447228

MAGAB
Melanoma-associated antigen 11

3

1

High-throughput

0.675

High

447234

CTBP2
C-terminal-binding protein 2

3

6

High-throughput

0.675

High

273669

NU155
Nuclear pore complex protein Nup155

3

1

High-throughput

0.667

High

433220

YES
Tyrosine-protein kinase Yes

3

11

High-throughput

0.667

High

433532

LYN
Tyrosine-protein kinase Lyn

3

11

High-throughput

0.667

High

447219

SRC
Proto-oncogene tyrosine-protein kinase Src

3

11

High-throughput

0.667

High

447249

EFR3A
Protein EFR3 homolog A

3

1

High-throughput

0.667

High

447267

CCNY
Cyclin-Y

3

3

High-throughput

0.667

High

447275

CTBL1
Beta-catenin-like protein 1

3

1

High-throughput

0.667

High

447279

SIR1
NAD-dependent protein deacetylase sirtuin-1

3

9

High-throughput

0.667

High

447301

SIR5
NAD-dependent protein deacylase sirtuin-5, mitochondrial

3

9

High-throughput

0.667

High

447307

EFR3B
Protein EFR3 homolog B

3

1

High-throughput

0.667

High

447257

Q6FHY5
MEOX2 protein

1

17

High-throughput

0.665

High

447221

H13
Histone H1.3

3

0

High-throughput

0.638

High

447248

CTBP1
C-terminal-binding protein 1

2

6

High-throughput

0.628

High

447232

MEOX2
Homeobox protein MOX-2

1

17

High-throughput

0.621

High

447229

NKX21
Homeobox protein Nkx-2.1

1

20

Small-scale

0.618

High

349075

RASH
GTPase HRas

2

3

High-throughput

0.611

High

411952

FYN
Tyrosine-protein kinase Fyn

2

11

High-throughput

0.611

High

447261

HDGR2
Hepatoma-derived growth factor-related protein 2

2

7

High-throughput

0.611

High

447268

NUP35
Nucleoporin NUP35

2

1

High-throughput

0.611

High

447278

VPP1
V-type proton ATPase 116 kDa subunit a 1

2

1

High-throughput

0.611

High

447281

TRI11
E3 ubiquitin-protein ligase TRIM11

2

14

High-throughput

0.611

High

447294

GBB4
Guanine nucleotide-binding protein subunit beta-4

2

2

High-throughput

0.611

High

447222

GNAZ
Guanine nucleotide-binding protein G(z) subunit alpha

3

4

High-throughput

0.609

High

447266

CCYL1
Cyclin-Y-like protein 1

3

3

High-throughput

0.609

High

204275

MS18B
Protein Mis18-beta

2

2

High-throughput

0.606

High

252956

HSF2B
Heat shock factor 2-binding protein

2

1

High-throughput

0.606

High

280511

KRT34
Keratin, type I cuticular Ha4

2

20

High-throughput

0.606

High

320650

LDOC1
Protein LDOC1

2

1

High-throughput

0.606

High

447220

TRI27
Zinc finger protein RFP

2

14

High-throughput

0.606

High

447235

KR106
Keratin-associated protein 10-6

2

20

High-throughput

0.606

High

447236

KR108
Keratin-associated protein 10-8

2

20

High-throughput

0.606

High

447241

KRA11
Keratin-associated protein 1-1

2

20

High-throughput

0.606

High

447242

TLE5
TLE family member 5

2

13

High-throughput

0.606

High

447245

TRAF2
TNF receptor-associated factor 2

2

20

High-throughput

0.606

High

447246

TRAF1
TNF receptor-associated factor 1

2

10

High-throughput

0.606

High

447247

CACO2
Calcium-binding and coiled-coil domain-containing protein 2

2

3

High-throughput

0.606

High

447251

K1H1
Keratin, type I cuticular Ha1

2

20

High-throughput

0.606

High

447253

USH1G
pre-mRNA splicing regulator USH1G

2

20

High-throughput

0.606

High

447254

MTUS2
Microtubule-associated tumor suppressor candidate 2

2

1

High-throughput

0.606

High

447255

PHF19
PHD finger protein 19

2

3

High-throughput

0.606

High

447256

MYOME
Myomegalin

2

1

High-throughput

0.606

High

447258

ZN774
Zinc finger protein 774

2

10

High-throughput

0.606

High

447265

ZN655
Zinc finger protein 655

2

4

High-throughput

0.606

High

447270

CEP70
Centrosomal protein of 70 kDa

2

1

High-throughput

0.606

High

447271

IKBD
NF-kappa-B inhibitor delta

2

20

High-throughput

0.606

High

447274

TEKT4
Tektin-4

2

4

High-throughput

0.606

High

447277

KIFA3
Kinesin-associated protein 3

2

1

High-throughput

0.606

High

447280

HOOK2
Protein Hook homolog 2

2

6

High-throughput

0.606

High

447284

TRIB3
Tribbles homolog 3

2

5

High-throughput

0.606

High

447285

TRAF4
TNF receptor-associated factor 4

2

20

High-throughput

0.606

High

447290

PRD14
PR domain zinc finger protein 14

2

13

High-throughput

0.606

High

447292

CARD9
Caspase recruitment domain-containing protein 9

2

3

High-throughput

0.606

High

447293

ZN552
Zinc finger protein 552

2

14

High-throughput

0.606

High

447295

Z286A
Zinc finger protein 286A

2

8

High-throughput

0.606

High

447297

HOME3
Homer protein homolog 3

2

4

High-throughput

0.606

High

447300

ASB6
Ankyrin repeat and SOCS box protein 6

2

20

High-throughput

0.606

High

447303

ZRAN1
Ubiquitin thioesterase ZRANB1

2

4

High-throughput

0.606

High

447308

AXIN2
Axin-2

2

8

High-throughput

0.606

High

274804

PALM
Paralemmin-1

2

0

High-throughput

0.585

High

61847

CC88B
Coiled-coil domain-containing protein 88B

2

0

High-throughput

0.580

High

447233

HAP1
Huntingtin-associated protein 1

2

0

High-throughput

0.580

High

447239

CSK2B
Casein kinase II subunit beta

2

0

High-throughput

0.580

High

447264

VPS52
Vacuolar protein sorting-associated protein 52 homolog

2

0

High-throughput

0.580

High

447296

ZC4H2
Zinc finger C4H2 domain-containing protein

2

0

High-throughput

0.580

High

60547

VP37C
Vacuolar protein sorting-associated protein 37C

2

4

High-throughput

0.574

High

447218

GNAO

2

4

High-throughput

0.558

High

447231

GNAQ
Guanine nucleotide-binding protein G(q) subunit alpha

2

4

High-throughput

0.558

High

447289

ULBP2
UL16-binding protein 2

2

3

High-throughput

0.558

High

62266

GG6L9
Golgin subfamily A member 6-like protein 9

2

10

High-throughput

0.553

High

66958

CRTP1
Cysteine-rich tail protein 1

2

5

High-throughput

0.553

High

447243

GOGA2
Golgin subfamily A member 2

2

6

High-throughput

0.553

High

447286

CNFN
Cornifelin

2

3

High-throughput

0.553

High

447288

TRI54
Tripartite motif-containing protein 54

2

19

High-throughput

0.553

High

447302

GOG6A
Golgin subfamily A member 6A

2

7

High-throughput

0.553

High

447304

TRIM1
Probable E3 ubiquitin-protein ligase MID2

2

20

High-throughput

0.553

High

447252

KRA63
Keratin-associated protein 6-3

1

4

High-throughput

0.515

High

447283

ZN363
RING finger and CHY zinc finger domain-containing protein 1

1

9

Small-scale

0.481

High

447305

CAPS1
Calcium-dependent secretion activator 1

1

3

High-throughput

0.481

High

335344

NB5R3
NADH-cytochrome b5 reductase 3

1

2

High-throughput

0.479

High

422129

NFL
Neurofilament light polypeptide

1

11

High-throughput

0.479

High

447230

IQGA1
Ras GTPase-activating-like protein IQGAP1

1

4

High-throughput

0.479

High

447237

ACTB
Actin, cytoplasmic 1

1

1

High-throughput

0.479

High

447238

RAB2A
Ras-related protein Rab-2A

1

4

High-throughput

0.479

High

447240

KC1G2
Casein kinase I isoform gamma-2

1

5

High-throughput

0.479

High

447250

GNA13
Guanine nucleotide-binding protein subunit alpha-13

1

4

High-throughput

0.479

High

447298

RBM12
RNA-binding protein 12

1

1

High-throughput

0.479

High

57980

A2RRN7
CADPS protein

1

3

High-throughput

0.470

High

447223

IF2B
Eukaryotic translation initiation factor 2 subunit 2

1

0

High-throughput

0.458

High

447260

MEAK7
MTOR-associated protein MEAK7

1

0

High-throughput

0.458

High

345747

MYC
Myc proto-oncogene protein

1

8

High-throughput

0.445

High

447262

TBC26
TBC1 domain family member 26

1

5

High-throughput

0.439

High

447282

CC136
Coiled-coil domain-containing protein 136

1

1

High-throughput

0.439

High

447224

GNA11
Guanine nucleotide-binding protein subunit alpha-11

1

4

High-throughput

0.437

High

447309

VPP2
V-type proton ATPase 116 kDa subunit a 2

1

1

High-throughput

0.437

High

447244

CNTN1
Contactin-1

3

0

High-throughput

0.347

High

447299

PHAG1
Phosphoprotein associated with glycosphingolipid-enriched microdomains 1

3

0

High-throughput

0.347

High

447272

OCC1
Overexpressed in colon carcinoma 1 protein

2

0

High-throughput

0.328

High

447259

ERIC5
Glutamate-rich protein 5

2

0

High-throughput

0.318

High

447269

SVIP
Small VCP/p97-interacting protein

2

0

High-throughput

0.318

High

447263

TEX11
Testis-expressed protein 11

2

0

High-throughput

0.316

High

447291

ZMY12
Zinc finger MYND domain-containing protein 12

2

0

High-throughput

0.316

High

447310

PLXD1
Plexin-D1

2

0

High-throughput

0.316

High

447273

UBTD2
Ubiquitin domain-containing protein 2

1

0

High-throughput

0.279

Low

447276

ASM3B
Acid sphingomyelinase-like phosphodiesterase 3b

1

0

High-throughput

0.249

Low

447306

EPCR
Endothelial protein C receptor

1

0

High-throughput

0.249

Low


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Last updated: 15 Jul 2024