Protein: ITPR3
Inositol 1,4,5-trisphosphate receptor type 3 (IP3 receptor isoform 3) (IP3R 3) (InsP3R3) (Type 3 inositol 1,4,5-trisphosphate receptor) (Type 3 InsP3 receptor)

Gene: ITPR3
Organism: Homo sapiens
Interactions: 202
UniProt ID: Q14573

Gene Ontology (top 5):
GO:0000822 - inositol hexakisphosphate binding
GO:0005220 - inositol 1,4,5-trisphosphate-gated calcium channel activity
GO:0005509 - calcium ion binding
GO:0005640 - nuclear outer membrane
GO:0005654 - nucleoplasm

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

823176

TRPC1
Short transient receptor potential channel 1

3

13

Small-scale

0.834

High

1037183

TRPC3
Short transient receptor potential channel 3

2

13

Small-scale

0.802

High

1055821

TRPC6
Short transient receptor potential channel 6

2

14

Small-scale

0.768

High

1055814

TRPC4
Short transient receptor potential channel 4

2

14

Small-scale

0.767

High

361218

TNNC2
Troponin C, skeletal muscle

1

7

High-throughput

0.691

High

648502

CALL3
Calmodulin-like protein 3

1

4

High-throughput

0.691

High

1055676

ITPR2
Inositol 1,4,5-trisphosphate receptor type 2

1

14

High-throughput

0.691

High

1055729

ITPR1
Inositol 1,4,5-trisphosphate-gated calcium channel ITPR1

1

14

High-throughput

0.691

High

1055748

CNGA4
Cyclic nucleotide-gated channel alpha-4

1

1

High-throughput

0.691

High

1055751

RASEF
Ras and EF-hand domain-containing protein

1

2

High-throughput

0.691

High

1055801

CABP2
Calcium-binding protein 2

1

10

High-throughput

0.691

High

1055810

PK2L2
Polycystin-2-like protein 2

1

6

High-throughput

0.691

High

58350

TESP1
Protein TESPA1

3

2

High-throughput

0.667

High

1055817

FBXL2
F-box/LRR-repeat protein 2

3

1

Small-scale

0.664

High

1055802

ANLN
Anillin

3

2

High-throughput

0.656

High

1055799

TRPC7
Short transient receptor potential channel 7

1

13

Small-scale

0.647

High

1055818

TRPC5
Short transient receptor potential channel 5

1

13

Small-scale

0.647

High

320320

SNP29
Synaptosomal-associated protein 29

3

0

High-throughput

0.638

High

160924

RAB7L
Ras-related protein Rab-7L1

2

6

High-throughput

0.628

High

686995

ACHA3
Neuronal acetylcholine receptor subunit alpha-3

2

1

High-throughput

0.628

High

1038964

KCC2G
Calcium/calmodulin-dependent protein kinase type II subunit gamma

2

11

High-throughput

0.628

High

1055766

LMBL2
Lethal(3)malignant brain tumor-like protein 2

2

1

High-throughput

0.628

High

1052970

FKBP8
Peptidyl-prolyl cis-trans isomerase FKBP8

1

11

High-throughput

0.618

High

1055741

TRI67
Tripartite motif-containing protein 67

1

1

High-throughput

0.618

High

278696

BODG
Gamma-butyrobetaine dioxygenase

3

2

High-throughput

0.609

High

1052865

FGL2
Fibroleukin

3

4

High-throughput

0.609

High

1055763

BAP1
Ubiquitin carboxyl-terminal hydrolase BAP1

1

0

Small-scale

0.589

High

890149

SC61B
Protein transport protein Sec61 subunit beta

2

2

High-throughput

0.584

High

484126

CALM3
Calmodulin-3

1

4

High-throughput

0.575

High

1047081

CAC1C
Voltage-dependent L-type calcium channel subunit alpha-1C

1

4

High-throughput

0.575

High

1055757

FRMD1
FERM domain-containing protein 1

2

1

High-throughput

0.574

High

1055775

TAFA4
Chemokine-like protein TAFA-4

2

2

High-throughput

0.574

High

1055733

KPCD1
Serine/threonine-protein kinase D1

2

8

High-throughput

0.571

High

1054121

BECN1
Beclin-1

1

1

Small-scale

0.561

High

131832

KRIT1
Krev interaction trapped protein 1

1

1

High-throughput

0.536

High

234217

PEPL
Periplakin

1

10

High-throughput

0.536

High

369605

ESR1
Estrogen receptor

1

6

High-throughput

0.536

High

565924

AATC
Aspartate aminotransferase, cytoplasmic

1

1

High-throughput

0.536

High

598118

FLNA
Filamin-A

1

1

High-throughput

0.536

High

654333

CALX
Calnexin

1

1

High-throughput

0.536

High

724830

MYH9
Myosin-9

1

6

High-throughput

0.536

High

771455

PSB10
Proteasome subunit beta type-10

1

1

High-throughput

0.536

High

802324

5HT3A
5-hydroxytryptamine receptor 3A

1

2

High-throughput

0.536

High

813028

CAZA2
F-actin-capping protein subunit alpha-2

1

2

High-throughput

0.536

High

849667

CCR6
C-C chemokine receptor type 6

1

2

High-throughput

0.536

High

984584

CALD1
Caldesmon

1

13

High-throughput

0.536

High

1038870

KCC2B
Calcium/calmodulin-dependent protein kinase type II subunit beta

1

11

High-throughput

0.536

High

1039062

KCC2D
Calcium/calmodulin-dependent protein kinase type II subunit delta

1

11

High-throughput

0.536

High

1048320

SCRB2
Lysosome membrane protein 2

1

1

High-throughput

0.536

High

1055732

P2RY6
P2Y purinoceptor 6

1

3

High-throughput

0.536

High

1055735

TTMP
TPA-induced transmembrane protein

1

1

High-throughput

0.536

High

1055753

SYNPO
Synaptopodin

1

3

High-throughput

0.536

High

1055762

ZNRF4
E3 ubiquitin-protein ligase ZNRF4

1

1

High-throughput

0.536

High

1055771

SGF29
SAGA-associated factor 29

1

2

High-throughput

0.536

High

1055772

MYO19
Unconventional myosin-XIX

1

3

High-throughput

0.536

High

1055812

STIM2
Stromal interaction molecule 2

1

1

High-throughput

0.536

High

1055819

KCC2A
Calcium/calmodulin-dependent protein kinase type II subunit alpha

1

11

High-throughput

0.536

High

1055822

IRAG1
Inositol 1,4,5-triphosphate receptor associated 1

1

3

High-throughput

0.536

High

409073

K2C8
Keratin, type II cytoskeletal 8

1

1

High-throughput

0.515

High

200389

HS12A
Heat shock 70 kDa protein 12A

1

0

High-throughput

0.513

High

314326

AHSA1
Activator of 90 kDa heat shock protein ATPase homolog 1

1

0

High-throughput

0.513

High

417722

G6PI
Glucose-6-phosphate isomerase

1

0

High-throughput

0.513

High

562162

ANFB
Natriuretic peptides B

1

0

High-throughput

0.513

High

789787

LPPRC
Leucine-rich PPR motif-containing protein, mitochondrial

1

0

High-throughput

0.513

High

834745

RBP2
E3 SUMO-protein ligase RanBP2

1

0

High-throughput

0.513

High

882734

STX17
Syntaxin-17

1

0

High-throughput

0.513

High

896892

ARP2
Actin-related protein 2

1

0

High-throughput

0.513

High

1053753

PIGH
Phosphatidylinositol N-acetylglucosaminyltransferase subunit H

1

0

High-throughput

0.513

High

1055743

CENPQ
Centromere protein Q

1

0

High-throughput

0.513

High

1055746

COMD2
COMM domain-containing protein 2

1

0

High-throughput

0.513

High

1055756

DYLT5
Dynein light chain Tctex-type 5

1

0

High-throughput

0.513

High

1055761

CC107
Coiled-coil domain-containing protein 107

1

0

High-throughput

0.513

High

1055787

GNL3
Guanine nucleotide-binding protein-like 3

1

0

High-throughput

0.513

High

1055791

COMD4
COMM domain-containing protein 4

1

0

High-throughput

0.513

High

1055811

VAPA
Vesicle-associated membrane protein-associated protein A

1

0

High-throughput

0.513

High

1055816

LIMA1
LIM domain and actin-binding protein 1

1

0

High-throughput

0.513

High

815873

MTR1A
Melatonin receptor type 1A

1

1

High-throughput

0.508

High

825698

MTR1B
Melatonin receptor type 1B

1

1

High-throughput

0.508

High

681845

AKT1
RAC-alpha serine/threonine-protein kinase

1

7

Small-scale

0.501

High

905893

PP1A
Serine/threonine-protein phosphatase PP1-alpha catalytic subunit

1

4

Small-scale

0.501

High

538233

ENPL
Endoplasmin

1

0

Small-scale

0.493

High

911386

RS11
Small ribosomal subunit protein uS17

1

0

High-throughput

0.493

High

1055780

PHB2
Prohibitin-2

1

0

High-throughput

0.493

High

796080

MAGA9
Melanoma-associated antigen 9

1

2

High-throughput

0.489

High

943629

KRT83
Keratin, type II cuticular Hb3

1

1

High-throughput

0.489

High

120438

RHOD
Rho-related GTP-binding protein RhoD

1

12

High-throughput

0.479

High

148813

CTRO
Citron Rho-interacting kinase

1

1

High-throughput

0.479

High

163805

AT2A1
Sarcoplasmic/endoplasmic reticulum calcium ATPase 1

1

6

High-throughput

0.479

High

255777

OBSL1
Obscurin-like protein 1

1

3

High-throughput

0.479

High

273799

NU155
Nuclear pore complex protein Nup155

1

2

High-throughput

0.479

High

315189

CNEP1
CTD nuclear envelope phosphatase 1

1

3

High-throughput

0.479

High

377325

GCR
Glucocorticoid receptor

1

6

High-throughput

0.479

High

390230

RPN1
Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit 1

1

2

High-throughput

0.479

High

390890

RPN2
Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit 2

1

2

High-throughput

0.479

High

408801

K1C18
Keratin, type I cytoskeletal 18

1

1

High-throughput

0.479

High

489420

BCL2
Apoptosis regulator Bcl-2

1

5

Small-scale

0.479

High

514687

CP2C9
Cytochrome P450 2C9

1

1

High-throughput

0.479

High

527454

LAMP2
Lysosome-associated membrane glycoprotein 2

1

2

High-throughput

0.479

High

545378

RAC2
Ras-related C3 botulinum toxin substrate 2

1

11

High-throughput

0.479

High

567058

CXA1
Gap junction alpha-1 protein

1

5

High-throughput

0.479

High

568668

KAPCA
cAMP-dependent protein kinase catalytic subunit alpha

1

9

High-throughput

0.479

High

573694

PTN1
Tyrosine-protein phosphatase non-receptor type 1

1

1

High-throughput

0.479

High

590924

BTF3
Transcription factor BTF3

1

2

High-throughput

0.479

High

591848

RAB4A
Ras-related protein Rab-4A

1

2

High-throughput

0.479

High

595224

LMNB1
Lamin-B1

1

1

High-throughput

0.479

High

720464

RFA3
Replication protein A 14 kDa subunit

1

1

High-throughput

0.479

High

726203

BASI
Basigin

1

3

High-throughput

0.479

High

751627

GRP75
Stress-70 protein, mitochondrial

1

1

Small-scale

0.479

High

795130

SSRA
Translocon-associated protein subunit alpha

1

2

High-throughput

0.479

High

813471

CAPZB
F-actin-capping protein subunit beta

1

2

High-throughput

0.479

High

825416

LMAN1
Protein ERGIC-53

1

1

High-throughput

0.479

High

838834

EMD
Emerin

1

2

High-throughput

0.479

High

844520

RAB5C
Ras-related protein Rab-5C

1

2

High-throughput

0.479

High

844926

RAB7A
Ras-related protein Rab-7a

1

7

High-throughput

0.479

High

845480

RAB9A
Ras-related protein Rab-9A

1

6

High-throughput

0.479

High

847468

BAP31
B-cell receptor-associated protein 31

1

2

High-throughput

0.479

High

874930

TERA
Transitional endoplasmic reticulum ATPase

1

5

Small-scale

0.479

High

890663

PTEN
Phosphatidylinositol 3,4,5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase PTEN

1

1

Small-scale

0.479

High

894011

CDC42
Cell division control protein 42 homolog

1

11

High-throughput

0.479

High

900471

RHOA
Transforming protein RhoA

1

12

High-throughput

0.479

High

950998

RHOG
Rho-related GTP-binding protein RhoG

1

11

High-throughput

0.479

High

961655

REEP5
Receptor expression-enhancing protein 5

1

1

High-throughput

0.479

High

969695

KIF23
Kinesin-like protein KIF23

1

3

High-throughput

0.479

High

974821

CAV1
Caveolin-1

1

3

Small-scale

0.479

High

1040103

STIM1
Stromal interaction molecule 1

1

1

High-throughput

0.479

High

1055730

TNIP1
TNFAIP3-interacting protein 1

1

9

High-throughput

0.479

High

1055731

KIF14
Kinesin-like protein KIF14

1

2

High-throughput

0.479

High

1055734

CAH9
Carbonic anhydrase 9

1

2

High-throughput

0.479

High

1055740

SYNE3
Nesprin-3

1

6

High-throughput

0.479

High

1055745

TM11B
Transmembrane protease serine 11B

1

3

High-throughput

0.479

High

1055750

MIRO2
Mitochondrial Rho GTPase 2

1

15

High-throughput

0.479

High

1055752

CXD3
Gap junction delta-3 protein

1

5

High-throughput

0.479

High

1055755

SIR6
NAD-dependent protein deacylase sirtuin-6

1

3

High-throughput

0.479

High

1055758

DHB11
Estradiol 17-beta-dehydrogenase 11

1

2

High-throughput

0.479

High

1055759

PDZD8
PDZ domain-containing protein 8

1

1

High-throughput

0.479

High

1055760

RBCC1
RB1-inducible coiled-coil protein 1

1

7

High-throughput

0.479

High

1055765

ESR2
Estrogen receptor beta

1

6

High-throughput

0.479

High

1055767

ERGI1
Endoplasmic reticulum-Golgi intermediate compartment protein 1

1

2

High-throughput

0.479

High

1055770

CHM4C
Charged multivesicular body protein 4c

1

2

High-throughput

0.479

High

1055773

RN170
E3 ubiquitin-protein ligase RNF170

1

2

High-throughput

0.479

High

1055774

DNJC1
DnaJ homolog subfamily C member 1

1

9

High-throughput

0.479

High

1055776

ERGI2
Endoplasmic reticulum-Golgi intermediate compartment protein 2

1

2

High-throughput

0.479

High

1055777

SEC62
Translocation protein SEC62

1

2

High-throughput

0.479

High

1055778

PARK7
Parkinson disease protein 7

1

1

Small-scale

0.479

High

1055779

DNJC7
DnaJ homolog subfamily C member 7

1

1

High-throughput

0.479

High

1055784

PCGF1
Polycomb group RING finger protein 1

1

2

High-throughput

0.479

High

1055785

DERL1
Derlin-1

1

2

High-throughput

0.479

High

1055788

FACD2
Fanconi anemia group D2 protein

1

1

High-throughput

0.479

High

1055790

LNP
Endoplasmic reticulum junction formation protein lunapark

1

3

High-throughput

0.479

High

1055792

CCDC8
Coiled-coil domain-containing protein 8

1

1

High-throughput

0.479

High

1055793

DJC25
DnaJ homolog subfamily C member 25

1

6

High-throughput

0.479

High

1055794

3BHS7
3 beta-hydroxysteroid dehydrogenase type 7

1

2

High-throughput

0.479

High

1055795

CHM4B
Charged multivesicular body protein 4b

1

2

High-throughput

0.479

High

1055796

PKHA4
Pleckstrin homology domain-containing family A member 4

1

2

High-throughput

0.479

High

1055797

TMT1A
Thiol S-methyltransferase TMT1A

1

2

High-throughput

0.479

High

1055800

B2L10
Bcl-2-like protein 10

1

2

Small-scale

0.479

High

1055803

PXMP2
Peroxisomal membrane protein 2

1

2

High-throughput

0.479

High

1055804

ST7
Suppressor of tumorigenicity 7 protein

1

2

High-throughput

0.479

High

1055805

SIR7
NAD-dependent protein deacetylase sirtuin-7

1

3

High-throughput

0.479

High

1055806

TMPS4
Transmembrane protease serine 4

1

3

High-throughput

0.479

High

1055807

OTULL
Inactive ubiquitin thioesterase OTULINL

1

2

High-throughput

0.479

High

1055809

ELOV5
Very long chain fatty acid elongase 5

1

2

High-throughput

0.479

High

1055813

B3GA1
Galactosylgalactosylxylosylprotein 3-beta-glucuronosyltransferase 1

1

2

High-throughput

0.479

High

1055815

SEC63
Translocation protein SEC63 homolog

1

3

High-throughput

0.479

High

1055820

LAMP3
Lysosome-associated membrane glycoprotein 3

1

2

High-throughput

0.479

High

233448

NUPR1
Nuclear protein 1

1

0

High-throughput

0.458

High

351376

TGFB1
Transforming growth factor beta-1 proprotein [Cleaved into: Latency-associated peptide

1

0

High-throughput

0.458

High

364273

TFR1
Transferrin receptor protein 1

1

0

High-throughput

0.458

High

374234

RAF1
RAF proto-oncogene serine/threonine-protein kinase

1

0

High-throughput

0.458

High

544970

AMPN
Aminopeptidase N

1

0

High-throughput

0.458

High

552726

RFA2
Replication protein A 32 kDa subunit

1

0

High-throughput

0.458

High

651203

RFA1
Replication protein A 70 kDa DNA-binding subunit

1

0

High-throughput

0.458

High

799225

EFTS
Elongation factor Ts, mitochondrial

1

0

High-throughput

0.458

High

881618

PEX3
Peroxisomal biogenesis factor 3

1

0

High-throughput

0.458

High

903228

WDR5
WD repeat-containing protein 5

1

0

High-throughput

0.458

High

917264

H4
Histone H4

1

0

High-throughput

0.458

High

931633

CSK2B
Casein kinase II subunit beta

1

0

High-throughput

0.458

High

967870

PO5F1
POU domain, class 5, transcription factor 1

1

0

High-throughput

0.458

High

1017631

STX4
Syntaxin-4

1

0

High-throughput

0.458

High

1055736

RN213
E3 ubiquitin-protein ligase RNF213

1

0

Small-scale

0.458

High

1055738

LMBRL
Protein LMBR1L

1

0

High-throughput

0.458

High

1055742

DPPA4
Developmental pluripotency-associated protein 4

1

0

High-throughput

0.458

High

1055749

TEX2
Testis-expressed protein 2

1

0

High-throughput

0.458

High

1055764

AKAP1
A-kinase anchor protein 1, mitochondrial

1

0

High-throughput

0.458

High

1055769

LRC59
Leucine-rich repeat-containing protein 59

1

0

High-throughput

0.458

High

1055781

SGMR1
Sigma non-opioid intracellular receptor 1

1

0

Small-scale

0.458

High

1055783

ESYT1
Extended synaptotagmin-1

1

0

High-throughput

0.458

High

1055786

DUS26
Dual specificity protein phosphatase 26

1

0

High-throughput

0.458

High

1055789

MK67I
MKI67 FHA domain-interacting nucleolar phosphoprotein

1

0

High-throughput

0.458

High

1055798

NANOG
Homeobox protein NANOG

1

0

High-throughput

0.458

High

1055808

MARH5
E3 ubiquitin-protein ligase MARCHF5

1

0

Small-scale

0.458

High

924577

GRB2
Growth factor receptor-bound protein 2

1

2

High-throughput

0.445

High

1032406

CTBP1
C-terminal-binding protein 1

1

1

High-throughput

0.445

High

914073

RB11A
Ras-related protein Rab-11A

1

1

High-throughput

0.437

High

1055737

A16L1
Autophagy-related protein 16-1

1

7

High-throughput

0.437

High

1055747

DYR2
Dihydrofolate reductase 2, mitochondrial

1

1

High-throughput

0.437

High

1055768

S2546
Mitochondrial outer membrane protein SLC25A46

1

1

High-throughput

0.437

High

1055754

RYBP
RING1 and YY1-binding protein

1

0

High-throughput

0.426

High

279298

DNJB5
DnaJ homolog subfamily B member 5

1

0

High-throughput

0.249

Low

1055739

LRC31
Leucine-rich repeat-containing protein 31

1

0

High-throughput

0.249

Low

1055744

PARPT
Protein mono-ADP-ribosyltransferase TIPARP

1

0

High-throughput

0.249

Low

1055782

TACO1
Translational activator of cytochrome c oxidase 1

1

0

High-throughput

0.249

Low


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Last updated: 15 Jul 2024