Protein: THB
Thyroid hormone receptor beta (Nuclear receptor subfamily 1 group A member 2) (c-erbA-2) (c-erbA-beta)

Gene: THB, Thrb
Organism: Mus musculus
Interactions: 117
UniProt ID: P37242

Gene Ontology (top 5):
GO:0000122 - negative regulation of transcription by RNA polymerase II
GO:0001223 - transcription coactivator binding
GO:0002157 - positive regulation of thyroid hormone receptor signaling pathway
GO:0003682 - chromatin binding
GO:0003700 - DNA-binding transcription factor activity

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

704567

RXRG
Retinoic acid receptor RXR-gamma

1

20

High-throughput

0.698

High

789711

THA
Thyroid hormone receptor alpha

1

19

High-throughput

0.618

High

104408

F6M2J9
Nuclear receptor coactivator-6 beta

2

20

Small-scale

0.595

High

704487

RXRA
Retinoic acid receptor RXR-alpha

1

20

Small-scale

0.590

High

686940

P85A
Phosphatidylinositol 3-kinase regulatory subunit alpha

2

20

Small-scale

0.584

High

267048

OSMR
Oncostatin-M-specific receptor subunit beta

1

5

High-throughput

0.553

High

789748

Q8BK32
Nuclear receptor co-repressor 1

2

20

Small-scale

0.533

High

59014

LMBL1
Lethal(3)malignant brain tumor-like protein 1

1

12

High-throughput

0.479

High

59099

CHD5
Chromodomain-helicase-DNA-binding protein 5

1

20

High-throughput

0.479

High

59333

PRD11
PR domain-containing protein 11

1

4

High-throughput

0.479

High

59401

CHD7
Chromodomain-helicase-DNA-binding protein 7

1

20

High-throughput

0.479

High

74262

EP300
Histone acetyltransferase p300

1

20

High-throughput

0.479

High

92640

SAFB1
Scaffold attachment factor B1

1

17

High-throughput

0.479

High

109304

G5E8N3
Histone-lysine N-methyltransferase SETDB1

1

16

Small-scale

0.479

High

148316

MNT
Max-binding protein MNT

1

13

High-throughput

0.479

High

312896

BSN
Protein bassoon

1

20

High-throughput

0.479

High

313455

LANC1
Glutathione S-transferase LANCL1

1

1

High-throughput

0.479

High

518665

EF1A1
Elongation factor 1-alpha 1

1

7

High-throughput

0.479

High

598654

G3P
Glyceraldehyde-3-phosphate dehydrogenase

1

4

High-throughput

0.479

High

663466

CRYAB
Alpha-crystallin B chain

1

4

High-throughput

0.479

High

789707

CSRP3
Cysteine and glycine-rich protein 3

1

8

High-throughput

0.479

High

789709

EF1A2
Elongation factor 1-alpha 2

1

7

High-throughput

0.479

High

789716

BACH2
Transcription regulator protein BACH2

1

14

High-throughput

0.479

High

789720

SHC1
SHC-transforming protein 1

1

19

High-throughput

0.479

High

789721

TBB5
Tubulin beta-5 chain

1

10

High-throughput

0.479

High

789724

TF65
Transcription factor p65

1

20

Small-scale

0.479

High

789725

SIAH2
E3 ubiquitin-protein ligase SIAH2

1

7

Small-scale

0.479

High

789727

Q2M4I6
SCAN domain-containing protein 1

1

8

Small-scale

0.479

High

789733

HCFC1
Host cell factor 1

1

5

High-throughput

0.479

High

789735

HAIR
Lysine-specific demethylase hairless

1

5

Small-scale

0.479

High

789736

ATRX
Transcriptional regulator ATRX

1

20

High-throughput

0.479

High

789737

K1C14
Keratin, type I cytoskeletal 14

1

12

High-throughput

0.479

High

789740

TRI37
E3 ubiquitin-protein ligase TRIM37

1

12

High-throughput

0.479

High

789741

AP2E
Transcription factor AP-2-epsilon

1

5

High-throughput

0.479

High

789753

THIM
3-ketoacyl-CoA thiolase, mitochondrial

1

1

High-throughput

0.479

High

789757

SYEP
Bifunctional glutamate/proline--tRNA ligase

1

1

High-throughput

0.479

High

789760

MYH9
Myosin-9

1

4

High-throughput

0.479

High

789761

K2C79
Keratin, type II cytoskeletal 79

1

15

High-throughput

0.479

High

789764

CLIP1
CAP-Gly domain-containing linker protein 1

1

8

High-throughput

0.479

High

789771

CST11
Cystatin-11

1

1

High-throughput

0.479

High

789779

NRIP2
Nuclear receptor-interacting protein 2

1

2

Small-scale

0.479

High

148493

AIP
AH receptor-interacting protein

1

9

Small-scale

0.462

High

789744

RNZ2
Zinc phosphodiesterase ELAC protein 2

1

0

High-throughput

0.458

High

789752

UBR7
Putative E3 ubiquitin-protein ligase UBR7

1

0

High-throughput

0.458

High

789758

GET1
Guided entry of tail-anchored proteins factor 1

1

0

High-throughput

0.458

High

789781

HTRA2
Serine protease HTRA2, mitochondrial

1

0

High-throughput

0.458

High

59535

CNTRL
Centriolin

1

12

High-throughput

0.437

High

59730

TBB1
Tubulin beta-1 chain

1

12

High-throughput

0.437

High

92747

D3Z482
Ankyrin repeat domain 26

1

8

High-throughput

0.437

High

266722

EF1B
Elongation factor 1-beta

1

2

High-throughput

0.437

High

312886

MAP7
Ensconsin

1

20

High-throughput

0.437

High

385195

K1C10
Keratin, type I cytoskeletal 10

1

14

High-throughput

0.437

High

403091

K2C1
Keratin, type II cytoskeletal 1

1

15

High-throughput

0.437

High

426885

TBA1B
Tubulin alpha-1B chain

1

16

High-throughput

0.437

High

547939

K2C8
Keratin, type II cytoskeletal 8

1

10

High-throughput

0.437

High

619278

NFH
Neurofilament heavy polypeptide

1

17

High-throughput

0.437

High

631779

MTAP2
Microtubule-associated protein 2

1

13

High-throughput

0.437

High

789703

NSF
Vesicle-fusing ATPase

1

9

High-throughput

0.437

High

789704

CBR1
Carbonyl reductase [NADPH] 1

1

4

High-throughput

0.437

High

789705

ADT1
ADP/ATP translocase 1

1

8

High-throughput

0.437

High

789706

K2C6A
Keratin, type II cytoskeletal 6A

1

15

High-throughput

0.437

High

789708

ADT2
ADP/ATP translocase 2

1

8

High-throughput

0.437

High

789710

ACTA
Actin, aortic smooth muscle

1

8

High-throughput

0.437

High

789712

TBA1A
Tubulin alpha-1A chain

1

16

High-throughput

0.437

High

789713

TBB4B
Tubulin beta-4B chain

1

10

High-throughput

0.437

High

789714

PTPR2
Receptor-type tyrosine-protein phosphatase N2

1

2

High-throughput

0.437

High

789717

KI20A
Kinesin-like protein KIF20A

1

8

High-throughput

0.437

High

789718

CPT1A
Carnitine O-palmitoyltransferase 1, liver isoform

1

2

High-throughput

0.437

High

789719

MASP1
Mannan-binding lectin serine protease 1

1

2

High-throughput

0.437

High

789722

ATPA
ATP synthase F(1) complex subunit alpha, mitochondrial

1

4

High-throughput

0.437

High

789723

KCND1
A-type voltage-gated potassium channel KCND1

1

1

High-throughput

0.437

High

789726

H1T
Histone H1t

1

3

High-throughput

0.437

High

789728

K22E
Keratin, type II cytoskeletal 2 epidermal

1

14

High-throughput

0.437

High

789729

K22O
Keratin, type II cytoskeletal 2 oral

1

15

High-throughput

0.437

High

789730

MFHA1
Malignant fibrous histiocytoma-amplified sequence 1 homolog

1

6

High-throughput

0.437

High

789731

ESYT3
Extended synaptotagmin-3

1

4

High-throughput

0.437

High

789732

FA2H
Fatty acid 2-hydroxylase

1

1

High-throughput

0.437

High

789734

FBN2
Fibrillin-2 [Cleaved into: Placensin]

1

2

High-throughput

0.437

High

789738

RPGFL
Rap guanine nucleotide exchange factor-like 1

1

2

High-throughput

0.437

High

789739

K2C73
Keratin, type II cytoskeletal 73

1

14

High-throughput

0.437

High

789742

RS9
Small ribosomal subunit protein uS4

1

2

High-throughput

0.437

High

789743

SYNE1
Nesprin-1

1

9

High-throughput

0.437

High

789746

EFTU
Elongation factor Tu, mitochondrial

1

10

High-throughput

0.437

High

789747

K2C75
Keratin, type II cytoskeletal 75

1

12

High-throughput

0.437

High

789749

ECHA
Trifunctional enzyme subunit alpha, mitochondrial

1

2

High-throughput

0.437

High

789751

ARF2
ADP-ribosylation factor 2

1

2

High-throughput

0.437

High

789754

CHD9
Chromodomain-helicase-DNA-binding protein 9

1

20

High-throughput

0.437

High

789755

GPC5
Glypican-5 [Cleaved into: Secreted glypican-5]

1

1

High-throughput

0.437

High

789756

SMOC2
SPARC-related modular calcium-binding protein 2

1

3

High-throughput

0.437

High

789759

S22A6
Solute carrier family 22 member 6

1

1

High-throughput

0.437

High

789762

CSPG4
Chondroitin sulfate proteoglycan 4

1

3

High-throughput

0.437

High

789763

ATPG
ATP synthase F(1) complex subunit gamma, mitochondrial

1

2

High-throughput

0.437

High

789765

K2C5
Keratin, type II cytoskeletal 5

1

14

High-throughput

0.437

High

789766

CPT1B
Carnitine O-palmitoyltransferase 1, muscle isoform

1

2

High-throughput

0.437

High

789770

CY1
Cytochrome c1, heme protein, mitochondrial

1

1

High-throughput

0.437

High

789772

TBB4A
Tubulin beta-4A chain

1

10

High-throughput

0.437

High

789773

EF1G
Elongation factor 1-gamma

1

2

High-throughput

0.437

High

789775

QCR2
Cytochrome b-c1 complex subunit 2, mitochondrial

1

2

High-throughput

0.437

High

789776

FBX3
F-box only protein 3

1

1

High-throughput

0.437

High

789777

CRIP2
Cysteine-rich protein 2

1

15

High-throughput

0.437

High

789778

NEK6
Serine/threonine-protein kinase Nek6

1

9

High-throughput

0.437

High

789782

TBA8
Tubulin alpha-8 chain

1

15

High-throughput

0.437

High

789783

CYH1
Cytohesin-1

1

1

High-throughput

0.437

High

789784

PLEC
Plectin

1

11

High-throughput

0.437

High

789785

K1C16
Keratin, type I cytoskeletal 16

1

15

High-throughput

0.437

High

60474

CTSRB
Cation channel sperm-associated auxiliary subunit beta

1

0

High-throughput

0.249

Low

204857

CLCN6
H(+)/Cl(-) exchange transporter 6

1

0

High-throughput

0.249

Low

313057

SC5D
Lathosterol oxidase

1

0

High-throughput

0.249

Low

715310

VTNC
Vitronectin

1

0

High-throughput

0.249

Low

789715

BEND4
BEN domain-containing protein 4

1

0

High-throughput

0.249

Low

789745

PRR5
Proline-rich protein 5

1

0

High-throughput

0.249

Low

789750

SPA2L
Spermatogenesis-associated protein 2-like protein

1

0

High-throughput

0.249

Low

789767

NLGN1
Neuroligin-1

1

0

High-throughput

0.249

Low

789768

ACON
Aconitate hydratase, mitochondrial

1

0

High-throughput

0.249

Low

789769

AGM1
Phosphoacetylglucosamine mutase

1

0

High-throughput

0.249

Low

789774

BORC5
BLOC-1-related complex subunit 5

1

0

High-throughput

0.249

Low

789780

SGPP1
Sphingosine-1-phosphate phosphatase 1

1

0

High-throughput

0.249

Low


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Last updated: 11Aug2025