Protein: HSDL2
Hydroxysteroid dehydrogenase-like protein 2 (EC 1.-.-.-) (Short chain dehydrogenase/reductase family 13C member 1)

Gene: HSDL2
Organism: Homo sapiens
Interactions: 120
UniProt ID: Q6YN16

Gene Ontology (top 5):
GO:0005739 - mitochondrion
GO:0005777 - peroxisome
GO:0016020 - membrane
GO:0016491 - oxidoreductase activity

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

227822

PRKN
E3 ubiquitin-protein ligase parkin

3

7

High-throughput

0.640

High

319888

HERC2
E3 ubiquitin-protein ligase HERC2

2

4

High-throughput

0.628

High

440584

ODPA
Pyruvate dehydrogenase E1 component subunit alpha, somatic form, mitochondrial

2

5

High-throughput

0.611

High

1168101

HSC20
Iron-sulfur cluster co-chaperone protein HscB

2

4

High-throughput

0.611

High

1168114

MIPEP
Mitochondrial intermediate peptidase

2

0

High-throughput

0.602

High

840272

PEX5
Peroxisomal targeting signal 1 receptor

2

7

Small-scale

0.584

High

1086624

CLPP
ATP-dependent Clp protease proteolytic subunit, mitochondrial

2

5

High-throughput

0.584

High

876146

PAR2
Proteinase-activated receptor 2

2

3

High-throughput

0.574

High

262859

CISY
Citrate synthase, mitochondrial

2

0

High-throughput

0.559

High

452813

DLDH
Dihydrolipoyl dehydrogenase, mitochondrial

1

1

High-throughput

0.536

High

728625

PPM1A
Protein phosphatase 1A

1

1

High-throughput

0.536

High

739164

ODO2
Dihydrolipoyllysine-residue succinyltransferase component of 2-oxoglutarate dehydrogenase complex, mitochondrial

1

1

High-throughput

0.536

High

1168133

NPS3A
Protein NipSnap homolog 3A

1

1

High-throughput

0.536

High

408633

KPCB
Protein kinase C beta type

2

2

High-throughput

0.521

High

417324

ENOA
Alpha-enolase

1

0

High-throughput

0.493

High

771462

PSB10
Proteasome subunit beta type-10

1

1

High-throughput

0.489

High

1085406

MK06
Mitogen-activated protein kinase 6

1

4

High-throughput

0.489

High

59212

VWA8
von Willebrand factor A domain-containing protein 8

1

3

High-throughput

0.479

High

116589

ADAS
Alkyldihydroxyacetonephosphate synthase, peroxisomal

1

4

High-throughput

0.479

High

258470

COQ9
Ubiquinone biosynthesis protein COQ9, mitochondrial

1

2

High-throughput

0.479

High

264941

MPPB
Mitochondrial-processing peptidase subunit beta

1

3

High-throughput

0.479

High

270058

RF1M
Peptide chain release factor 1, mitochondrial

1

1

High-throughput

0.479

High

294953

RECQ4
ATP-dependent DNA helicase Q4

1

2

High-throughput

0.479

High

348743

RASN
GTPase NRas

1

4

High-throughput

0.479

High

373394

CATA
Catalase

1

5

High-throughput

0.479

High

377412

GCR
Glucocorticoid receptor

1

10

High-throughput

0.479

High

429076

ADRB2
Beta-2 adrenergic receptor

1

3

High-throughput

0.479

High

499854

CH60
60 kDa heat shock protein, mitochondrial

1

2

High-throughput

0.479

High

777607

MDHM
Malate dehydrogenase, mitochondrial

1

1

High-throughput

0.479

High

803146

IF2M
Translation initiation factor IF-2, mitochondrial

1

4

High-throughput

0.479

High

813559

CAPZB
F-actin-capping protein subunit beta

1

1

High-throughput

0.479

High

921619

GBB2
Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-2

1

4

High-throughput

0.479

High

1014406

MPPA
Mitochondrial-processing peptidase subunit alpha

1

3

High-throughput

0.479

High

1020467

TRAP1
Heat shock protein 75 kDa, mitochondrial

1

1

High-throughput

0.479

High

1045785

AUHM
Methylglutaconyl-CoA hydratase, mitochondrial

1

2

High-throughput

0.479

High

1064422

U5S1
116 kDa U5 small nuclear ribonucleoprotein component

1

2

High-throughput

0.479

High

1067993

PDK1
[Pyruvate dehydrogenase

1

2

High-throughput

0.479

High

1157933

RUSD3
Mitochondrial mRNA pseudouridine synthase RPUSD3

1

1

High-throughput

0.479

High

1168097

FAKD5
FAST kinase domain-containing protein 5, mitochondrial

1

1

High-throughput

0.479

High

1168099

CNTRL
Centriolin

1

1

High-throughput

0.479

High

1168106

ESR2
Estrogen receptor beta

1

10

High-throughput

0.479

High

1168107

FAKD4
FAST kinase domain-containing protein 4

1

1

High-throughput

0.479

High

1168110

RUSD4
Pseudouridylate synthase RPUSD4, mitochondrial

1

1

High-throughput

0.479

High

1168111

MTEF3
Transcription termination factor 3, mitochondrial

1

1

High-throughput

0.479

High

1168113

EFGM
Elongation factor G, mitochondrial

1

2

High-throughput

0.479

High

1168116

TMM70
Transmembrane protein 70, mitochondrial

1

1

High-throughput

0.479

High

1168125

ACAD9
Complex I assembly factor ACAD9, mitochondrial

1

2

High-throughput

0.479

High

1168134

RF1ML
Peptide chain release factor 1-like, mitochondrial

1

1

High-throughput

0.479

High

1168138

FND3A
Fibronectin type-III domain-containing protein 3A

1

2

High-throughput

0.479

High

173592

NPHP1
Nephrocystin-1

1

0

High-throughput

0.458

High

298602

UFL1
E3 UFM1-protein ligase 1

1

0

High-throughput

0.458

High

327474

TRUB2
Pseudouridylate synthase TRUB2, mitochondrial

1

0

High-throughput

0.458

High

486557

COX8A
Cytochrome c oxidase subunit 8A, mitochondrial

1

0

High-throughput

0.458

High

737379

LONM
Lon protease homolog, mitochondrial

1

0

High-throughput

0.458

High

789852

LPPRC
Leucine-rich PPR motif-containing protein, mitochondrial

1

0

High-throughput

0.458

High

799264

EFTS
Elongation factor Ts, mitochondrial

1

0

High-throughput

0.458

High

827444

EFTU
Elongation factor Tu, mitochondrial

1

0

High-throughput

0.458

High

958949

TFAM
Transcription factor A, mitochondrial

1

0

High-throughput

0.458

High

981301

SSBP
Single-stranded DNA-binding protein, mitochondrial

1

0

High-throughput

0.458

High

990132

C1QBP
Complement component 1 Q subcomponent-binding protein, mitochondrial

1

0

High-throughput

0.458

High

1050988

ICT1
Large ribosomal subunit protein mL62

1

0

High-throughput

0.458

High

1128163

SYAM
Alanine--tRNA ligase, mitochondrial

1

0

High-throughput

0.458

High

1152871

MRM1
rRNA methyltransferase 1, mitochondrial

1

0

High-throughput

0.458

High

1168109

MCUR1
Mitochondrial calcium uniporter regulator 1

1

0

High-throughput

0.458

High

1168115

TACO1
Translational activator of cytochrome c oxidase 1

1

0

High-throughput

0.458

High

1168117

MIC26
MICOS complex subunit MIC26

1

0

High-throughput

0.458

High

1168118

TR61B
tRNA

1

0

High-throughput

0.458

High

1168119

HINT2
Adenosine 5'-monophosphoramidase HINT2

1

0

High-throughput

0.458

High

1168120

RT26
Small ribosomal subunit protein mS26

1

0

High-throughput

0.458

High

1168121

IF3M
Translation initiation factor IF-3, mitochondrial

1

0

High-throughput

0.458

High

1168128

SIR3
NAD-dependent protein deacetylase sirtuin-3, mitochondrial

1

0

Small-scale

0.458

High

1168129

EXD2
Exonuclease 3'-5' domain-containing protein 2

1

0

High-throughput

0.458

High

1168131

RMND1
Required for meiotic nuclear division protein 1 homolog

1

0

High-throughput

0.458

High

1168132

MRES1
Mitochondrial transcription rescue factor 1

1

0

High-throughput

0.458

High

1130231

LRRK2
Leucine-rich repeat serine/threonine-protein kinase 2

1

4

High-throughput

0.445

High

308812

KI20A
Kinesin-like protein KIF20A

1

9

High-throughput

0.437

High

553005

RFA2
Replication protein A 32 kDa subunit

1

4

High-throughput

0.437

High

651506

RFA1
Replication protein A 70 kDa DNA-binding subunit

1

5

High-throughput

0.437

High

720756

RFA3
Replication protein A 14 kDa subunit

1

4

High-throughput

0.437

High

824125

NR2C2
Nuclear receptor subfamily 2 group C member 2

1

1

High-throughput

0.437

High

900610

RHOA
Transforming protein RhoA

1

8

High-throughput

0.437

High

903322

WDR5
WD repeat-containing protein 5

1

5

High-throughput

0.437

High

951096

RHOG
Rho-related GTP-binding protein RhoG

1

6

High-throughput

0.437

High

1035840

BIRC3
Baculoviral IAP repeat-containing protein 3

1

4

High-throughput

0.437

High

1050228

IKKE
Inhibitor of nuclear factor kappa-B kinase subunit epsilon

1

2

High-throughput

0.437

High

1147608

FTM
Protein fantom

1

1

High-throughput

0.437

High

1156613

TECT3
Tectonic-3

1

2

High-throughput

0.437

High

1165697

LMBRL
Protein LMBR1L

1

2

High-throughput

0.437

High

1168096

TRI67
Tripartite motif-containing protein 67

1

12

High-throughput

0.437

High

1168098

PARPT
Protein mono-ADP-ribosyltransferase TIPARP

1

1

High-throughput

0.437

High

1168103

NUP43
Nucleoporin Nup43

1

8

High-throughput

0.437

High

1168108

ZUP1
Zinc finger-containing ubiquitin peptidase 1

1

3

High-throughput

0.437

High

1168122

PKHA4
Pleckstrin homology domain-containing family A member 4

1

6

High-throughput

0.437

High

1168123

EGLN3
Prolyl hydroxylase EGLN3

1

2

High-throughput

0.437

High

1168126

ANLN
Anillin

1

2

High-throughput

0.437

High

1168130

PIHD1
PIH1 domain-containing protein 1

1

1

High-throughput

0.437

High

1168135

ZRAN1
Ubiquitin thioesterase ZRANB1

1

10

High-throughput

0.437

High

1168137

FBW1A
F-box/WD repeat-containing protein 1A

1

5

High-throughput

0.437

High

1168140

KIF3A
Kinesin-like protein KIF3A

1

3

High-throughput

0.437

High

1168141

TRRAP
Transformation/transcription domain-associated protein

1

1

High-throughput

0.437

High

111293

J3KPF9
Kinesin-like protein

1

3

High-throughput

0.407

High

306215

GBRAP
Gamma-aminobutyric acid receptor-associated protein

1

3

High-throughput

0.407

High

349418

RASH
GTPase HRas

1

4

High-throughput

0.407

High

402173

JUN
Transcription factor Jun

1

2

High-throughput

0.407

High

1153262

PKHA7
Pleckstrin homology domain-containing family A member 7

1

10

High-throughput

0.407

High

1168112

NEUL4
Neuralized-like protein 4

2

0

High-throughput

0.328

High

261840

NDUS6
NADH dehydrogenase [ubiquinone] iron-sulfur protein 6, mitochondrial

1

0

High-throughput

0.279

Low

648529

CALL3
Calmodulin-like protein 3

1

0

High-throughput

0.279

Low

893384

PRPS1
Ribose-phosphate pyrophosphokinase 1

1

0

High-throughput

0.279

Low

1038476

HDAC1
Histone deacetylase 1

1

0

High-throughput

0.279

Low

1168100

LHPL4
LHFPL tetraspan subfamily member 4 protein

1

0

High-throughput

0.279

Low

1168102

F133A
Protein FAM133A

1

0

High-throughput

0.279

Low

868229

ATX3
Ataxin-3

1

0

Small-scale

0.249

Low

1033953

XRCC4
DNA repair protein XRCC4

1

0

High-throughput

0.249

Low

1168104

NUP35
Nucleoporin NUP35

1

0

High-throughput

0.249

Low

1168105

DNJC9
DnaJ homolog subfamily C member 9

1

0

High-throughput

0.249

Low

1168124

MET17
Ribosome assembly protein METTL17, mitochondrial

1

0

High-throughput

0.249

Low

1168127

FBX6
F-box only protein 6

1

0

High-throughput

0.249

Low

1168136

DNPEP
Aspartyl aminopeptidase

1

0

High-throughput

0.249

Low

1168139

AAR2
Protein AAR2 homolog

1

0

High-throughput

0.249

Low


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Last updated: 15 Jul 2024