Protein: FOXM1
Forkhead box protein M1 (Forkhead-related protein FKHL16) (Hepatocyte nuclear factor 3 forkhead homolog 11) (HFH-11) (HNF-3/fork-head homolog 11) (M-phase phosphoprotein 2) (MPM-2 reactive phosphoprotein 2) (Transcription factor Trident) (Winged-helix factor from INS-1 cells)

Gene: FOXM1
Organism: Homo sapiens
Interactions: 113
UniProt ID: Q08050

Gene Ontology (top 5):
GO:0000086 - G2/M transition of mitotic cell cycle
GO:0000122 - negative regulation of transcription by RNA polymerase II
GO:0000785 - chromatin
GO:0000977 - RNA polymerase II transcription regulatory region sequence-specific DNA binding
GO:0000981 - DNA-binding transcription factor activity, RNA polymerase II-specific

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

993334

CBP
CREB-binding protein

4

16

Small-scale

0.696

High

993357

FZR1
Fizzy-related protein homolog

4

9

Small-scale

0.676

High

414889

CDK1
Cyclin-dependent kinase 1

3

5

Small-scale

0.674

High

861714

PLK1
Serine/threonine-protein kinase PLK1

3

5

Small-scale

0.670

High

993339

OTUB1
Ubiquitin thioesterase OTUB1

4

0

Small-scale

0.667

High

717029

CTNB1
Catenin beta-1

2

5

Small-scale

0.650

High

538528

CCNB1
G2/mitotic-specific cyclin-B1

3

2

Small-scale

0.650

High

624578

CCNE1
G1/S-specific cyclin-E1

2

2

Small-scale

0.646

High

414258

RB
Retinoblastoma-associated protein

2

6

Small-scale

0.634

High

206830

FOXO3
Forkhead box protein O3

1

20

Small-scale

0.618

High

978727

TF65
Transcription factor p65

1

11

Small-scale

0.618

High

993331

BANP
Protein BANP

2

1

High-throughput

0.613

High

625387

CDK2
Cyclin-dependent kinase 2

2

5

Small-scale

0.611

High

486897

MYBB
Myb-related protein B

2

3

Small-scale

0.611

High

993355

FBXL2
F-box/LRR-repeat protein 2

3

1

Small-scale

0.599

High

672818

CDC27
Cell division cycle protein 27 homolog

2

1

Small-scale

0.584

High

800576

UBP5
Ubiquitin carboxyl-terminal hydrolase 5

2

7

Small-scale

0.584

High

993354

UBP21
Ubiquitin carboxyl-terminal hydrolase 21

1

1

Small-scale

0.578

High

993308

FOXM1
Forkhead box protein M1

1

17

High-throughput

0.575

High

515410

CDK4
Cyclin-dependent kinase 4

1

7

Small-scale

0.569

High

960158

CDK6
Cyclin-dependent kinase 6

1

7

Small-scale

0.569

High

435068

SP1
Transcription factor Sp1

1

17

Small-scale

0.561

High

548092

UCHL3
Ubiquitin carboxyl-terminal hydrolase isozyme L3

1

5

Small-scale

0.561

High

950152

SMAD3
Mothers against decapentaplegic homolog 3

1

4

Small-scale

0.561

High

993317

UBP39
Ubiquitin carboxyl-terminal hydrolase 39

1

9

Small-scale

0.561

High

993338

SIR1
NAD-dependent protein deacetylase sirtuin-1

1

3

Small-scale

0.561

High

993360

DCAF1
DDB1- and CUL4-associated factor 1

1

6

Small-scale

0.561

High

132135

PESC
Pescadillo homolog

1

1

High-throughput

0.554

High

993310

ORC2
Origin recognition complex subunit 2

1

3

High-throughput

0.554

High

993347

TF7L2
Transcription factor 7-like 2

1

20

Small-scale

0.554

High

993344

ZBTB3
Zinc finger and BTB domain-containing protein 3

1

17

High-throughput

0.541

High

199721

SNUT1
U4/U6.U5 tri-snRNP-associated protein 1

1

1

High-throughput

0.536

High

209922

PRC1
Protein regulator of cytokinesis 1

1

1

High-throughput

0.536

High

229375

SMCA5
SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A member 5

1

20

High-throughput

0.536

High

272109

U520
U5 small nuclear ribonucleoprotein 200 kDa helicase

1

9

High-throughput

0.536

High

311532

SMC2
Structural maintenance of chromosomes protein 2

1

17

High-throughput

0.536

High

745134

RBMX
RNA-binding motif protein, X chromosome

1

7

High-throughput

0.536

High

783021

SYIC
Isoleucine--tRNA ligase, cytoplasmic

1

15

High-throughput

0.536

High

814426

SYQ
Glutamine--tRNA ligase

1

1

High-throughput

0.536

High

869623

TERF1
Telomeric repeat-binding factor 1

1

2

High-throughput

0.536

High

993312

BMS1
Ribosome biogenesis protein BMS1 homolog

1

2

High-throughput

0.536

High

993313

KIF22
Kinesin-like protein KIF22

1

2

High-throughput

0.536

High

993324

LIN54
Protein lin-54 homolog

1

1

High-throughput

0.536

High

993325

PRP8
Pre-mRNA-processing-splicing factor 8

1

1

High-throughput

0.536

High

993329

KAISO
Transcriptional regulator Kaiso

1

4

High-throughput

0.536

High

993333

DNJC9
DnaJ homolog subfamily C member 9

1

4

High-throughput

0.536

High

993343

PAR6B
Partitioning defective 6 homolog beta

1

4

High-throughput

0.536

High

993345

ECT2
Protein ECT2

1

1

High-throughput

0.536

High

993352

LRWD1
Leucine-rich repeat and WD repeat-containing protein 1

1

3

High-throughput

0.536

High

993356

TF3C4
General transcription factor 3C polypeptide 4

1

4

High-throughput

0.536

High

993358

DDX52
Probable ATP-dependent RNA helicase DDX52

1

5

High-throughput

0.536

High

256494

ZC11A
Zinc finger CCCH domain-containing protein 11A

1

0

High-throughput

0.530

High

673472

MPIP2
M-phase inducer phosphatase 2

1

1

Small-scale

0.515

High

993318

DEP1A
DEP domain-containing protein 1A

1

0

High-throughput

0.513

High

993319

RNH2B
Ribonuclease H2 subunit B

1

0

High-throughput

0.513

High

993320

LIN9
Protein lin-9 homolog

1

0

High-throughput

0.513

High

993328

TRM1L
TRMT1-like protein

1

0

High-throughput

0.513

High

993332

KI18A
Kinesin-like protein KIF18A

1

0

High-throughput

0.513

High

993340

LIN37
Protein lin-37 homolog

1

0

High-throughput

0.513

High

541351

SYDC
Aspartate--tRNA ligase, cytoplasmic

1

2

High-throughput

0.506

High

331263

CHK2
Serine/threonine-protein kinase Chk2

1

4

Small-scale

0.501

High

928078

SUMO1
Small ubiquitin-related modifier 1

1

1

Small-scale

0.501

High

930170

UBC9
SUMO-conjugating enzyme UBC9

1

2

Small-scale

0.501

High

993316

HIF1A
Hypoxia-inducible factor 1-alpha

1

11

Small-scale

0.501

High

993326

ANR12
Ankyrin repeat domain-containing protein 12

1

9

Small-scale

0.501

High

46894

PNT87
Transcriptional regulator PINT87aa

1

0

Small-scale

0.493

High

515842

PRPS2
Ribose-phosphate pyrophosphokinase 2

1

1

High-throughput

0.489

High

993350

SYLC
Leucine--tRNA ligase, cytoplasmic

1

15

High-throughput

0.489

High

993353

HERC5
E3 ISG15--protein ligase HERC5

1

5

High-throughput

0.489

High

122696

MEN1
Menin

1

4

High-throughput

0.479

High

282634

RNF8
E3 ubiquitin-protein ligase RNF8

1

6

Small-scale

0.479

High

346618

MYC
Myc proto-oncogene protein

1

11

High-throughput

0.479

High

386605

P53
Cellular tumor antigen p53

1

15

High-throughput

0.479

High

431778

HS90A
Heat shock protein HSP 90-alpha

1

4

High-throughput

0.479

High

438104

HS90B
Heat shock protein HSP 90-beta

1

4

High-throughput

0.479

High

508961

TOP2A
DNA topoisomerase 2-alpha

1

3

Small-scale

0.479

High

551128

ITF2
Transcription factor 4

1

1

Small-scale

0.479

High

668629

PML
Protein PML

1

6

High-throughput

0.479

High

673391

MPIP1
M-phase inducer phosphatase 1

1

1

Small-scale

0.479

High

835346

GSK3A
Glycogen synthase kinase-3 alpha

1

3

Small-scale

0.479

High

835696

GSK3B
Glycogen synthase kinase-3 beta

1

4

Small-scale

0.479

High

843629

FXR1
RNA-binding protein FXR1

1

1

Small-scale

0.479

High

918315

H2B1C
Histone H2B type 1-C/E/F/G/I

1

1

High-throughput

0.479

High

993309

EP300
Histone acetyltransferase p300

1

19

Small-scale

0.479

High

993314

EZH2
Histone-lysine N-methyltransferase EZH2

1

1

Small-scale

0.479

High

993323

OTU7B
OTU domain-containing protein 7B

1

5

Small-scale

0.479

High

993336

IRF7
Interferon regulatory factor 7

1

4

Small-scale

0.479

High

993337

FBXW7
F-box/WD repeat-containing protein 7

1

12

Small-scale

0.479

High

993359

TRRAP
Transformation/transcription domain-associated protein

1

3

High-throughput

0.479

High

993361

PARP3
Protein mono-ADP-ribosyltransferase PARP3

1

7

Small-scale

0.479

High

154023

TERT
Telomerase reverse transcriptase

1

0

Small-scale

0.458

High

170640

AXIN1
Axin-1

1

0

Small-scale

0.458

High

781348

BCL6
B-cell lymphoma 6 protein

1

0

Small-scale

0.458

High

993315

CDC37
Hsp90 co-chaperone Cdc37

1

0

High-throughput

0.458

High

993330

RN168
E3 ubiquitin-protein ligase RNF168

1

0

Small-scale

0.458

High

993335

CSN5
COP9 signalosome complex subunit 5

1

0

Small-scale

0.458

High

993351

DNM3B
DNA

1

0

Small-scale

0.458

High

72482

B4DE54
Protein BANP

1

1

High-throughput

0.457

High

993341

LZTS2
Leucine zipper putative tumor suppressor 2

1

7

High-throughput

0.437

High

993342

TRI56
E3 ubiquitin-protein ligase TRIM56

1

7

Small-scale

0.437

High

993346

GORS2
Golgi reassembly-stacking protein 2

1

3

Small-scale

0.437

High

993348

SYIM
Isoleucine--tRNA ligase, mitochondrial

1

15

High-throughput

0.437

High

993349

SLX9
Ribosome biogenesis protein SLX9 homolog

1

1

Small-scale

0.437

High

56611

PIPSL
Putative PIP5K1A and PSMD4-like protein

1

1

High-throughput

0.407

High

179166

COPT1
High affinity copper uptake protein 1

1

0

High-throughput

0.279

Low

364869

FRIL
Ferritin light chain

1

0

High-throughput

0.279

Low

486251

CCL3
C-C motif chemokine 3

1

0

High-throughput

0.279

Low

560055

CTLA4
Cytotoxic T-lymphocyte protein 4

1

0

High-throughput

0.279

Low

993327

SYPM
Probable proline--tRNA ligase, mitochondrial

1

0

High-throughput

0.279

Low

993311

OS9
Protein OS-9

1

0

High-throughput

0.251

Low

993321

FBX31
F-box only protein 31

1

0

Small-scale

0.249

Low

993322

DCA15
DDB1- and CUL4-associated factor 15

1

0

High-throughput

0.249

Low


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Last updated: 15 Jul 2024