Protein: GUF1
Translation factor GUF1, mitochondrial (EC 3.6.5.-) (Elongation factor 4 homolog) (EF-4) (GTPase GUF1) (Ribosomal back-translocase)

Gene: GUF1
Organism: Homo sapiens
Interactions: 102
UniProt ID: Q8N442

Gene Ontology (top 5):
GO:0003924 - GTPase activity
GO:0005525 - GTP binding
GO:0005739 - mitochondrion
GO:0005743 - mitochondrial inner membrane
GO:0005759 - mitochondrial matrix

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

1232855

RT07
Small ribosomal subunit protein uS7m

2

4

High-throughput

0.628

High

173061

RT12
Small ribosomal subunit protein uS12m

1

2

High-throughput

0.618

High

799283

EFTS
Elongation factor Ts, mitochondrial

1

7

High-throughput

0.618

High

803160

IF2M
Translation initiation factor IF-2, mitochondrial

1

11

High-throughput

0.618

High

827484

EFTU
Elongation factor Tu, mitochondrial

1

5

High-throughput

0.618

High

1232826

RRFM
Ribosome-recycling factor, mitochondrial

1

1

High-throughput

0.618

High

1232829

EFGM
Elongation factor G, mitochondrial

1

13

High-throughput

0.618

High

1232839

MTG2
Mitochondrial ribosome-associated GTPase 2

1

4

High-throughput

0.618

High

1232857

RM11
Large ribosomal subunit protein uL11m

1

2

High-throughput

0.618

High

352656

TNFA
Tumor necrosis factor

3

3

High-throughput

0.609

High

262884

CISY
Citrate synthase, mitochondrial

2

2

High-throughput

0.584

High

1086657

CLPP
ATP-dependent Clp protease proteolytic subunit, mitochondrial

2

4

High-throughput

0.584

High

527618

LAMP2
Lysosome-associated membrane glycoprotein 2

2

1

High-throughput

0.574

High

1232818

TSYL6
Testis-specific Y-encoded-like protein 6

2

1

High-throughput

0.574

High

1232850

C5AR2
C5a anaphylatoxin chemotactic receptor 2

2

4

High-throughput

0.574

High

254722

PTCD1
Pentatricopeptide repeat-containing protein 1, mitochondrial

1

2

High-throughput

0.536

High

815397

UCRI
Cytochrome b-c1 complex subunit Rieske, mitochondrial

1

1

High-throughput

0.536

High

1159901

FAHD1
Oxaloacetate decarboxylase, mitochondrial

1

1

High-throughput

0.536

High

1218813

HSC20
Iron-sulfur cluster co-chaperone protein HscB

1

2

High-throughput

0.536

High

1232828

MASU1
Mitochondrial assembly of ribosomal large subunit protein 1

1

1

High-throughput

0.536

High

1232843

SYSM
Serine--tRNA ligase, mitochondrial

1

2

High-throughput

0.536

High

1232856

SYYM
Tyrosine--tRNA ligase, mitochondrial

1

1

High-throughput

0.536

High

369992

ESR1
Estrogen receptor

2

8

High-throughput

0.521

High

1232820

HUMMR
Protein MGARP

1

0

High-throughput

0.513

High

1232853

AMACR
Alpha-methylacyl-CoA racemase

1

0

High-throughput

0.513

High

234549

DSCAM
Cell adhesion molecule DSCAM

1

2

High-throughput

0.494

High

126620

P2Y10
Putative P2Y purinoceptor 10

1

4

High-throughput

0.489

High

207253

TNF14
Tumor necrosis factor ligand superfamily member 14

1

3

High-throughput

0.489

High

442914

FCG3A
Low affinity immunoglobulin gamma Fc region receptor III-A

1

4

High-throughput

0.489

High

685273

CEAM8
Carcinoembryonic antigen-related cell adhesion molecule 8

1

1

High-throughput

0.489

High

796134

MAGA9
Melanoma-associated antigen 9

1

2

High-throughput

0.489

High

814277

GLR
Glucagon receptor

1

1

High-throughput

0.489

High

825072

PTH2R
Parathyroid hormone 2 receptor

1

1

High-throughput

0.489

High

1100204

MICB
MHC class I polypeptide-related sequence B

1

2

High-throughput

0.489

High

1120216

LRC23
Leucine-rich repeat-containing protein 23

1

1

High-throughput

0.489

High

1232831

PFD5
Prefoldin subunit 5

1

1

High-throughput

0.489

High

1232858

GPR45
Probable G-protein coupled receptor 45

1

3

High-throughput

0.489

High

59230

VWA8
von Willebrand factor A domain-containing protein 8

1

2

High-throughput

0.479

High

63394

MET15
12S rRNA N4-methylcytidine

1

1

High-throughput

0.479

High

270073

RF1M
Peptide chain release factor 1, mitochondrial

1

5

High-throughput

0.479

High

327491

TRUB2
Pseudouridylate synthase TRUB2, mitochondrial

1

2

High-throughput

0.479

High

440617

ODPA
Pyruvate dehydrogenase E1 component subunit alpha, somatic form, mitochondrial

1

5

High-throughput

0.479

High

455651

PARP1
Poly [ADP-ribose] polymerase 1

1

1

High-throughput

0.479

High

486573

COX8A
Cytochrome c oxidase subunit 8A, mitochondrial

1

1

High-throughput

0.479

High

737401

LONM
Lon protease homolog, mitochondrial

1

2

High-throughput

0.479

High

777638

MDHM
Malate dehydrogenase, mitochondrial

1

3

High-throughput

0.479

High

789879

LPPRC
Leucine-rich PPR motif-containing protein, mitochondrial

1

2

High-throughput

0.479

High

958965

TFAM
Transcription factor A, mitochondrial

1

4

High-throughput

0.479

High

981329

SSBP
Single-stranded DNA-binding protein, mitochondrial

1

4

High-throughput

0.479

High

990173

C1QBP
Complement component 1 Q subcomponent-binding protein, mitochondrial

1

2

High-throughput

0.479

High

1014423

MPPA
Mitochondrial-processing peptidase subunit alpha

1

6

High-throughput

0.479

High

1017958

GRSF1
G-rich sequence factor 1

1

6

High-throughput

0.479

High

1020487

TRAP1
Heat shock protein 75 kDa, mitochondrial

1

13

High-throughput

0.479

High

1045801

AUHM
Methylglutaconyl-CoA hydratase, mitochondrial

1

7

High-throughput

0.479

High

1051011

ICT1
Large ribosomal subunit protein mL62

1

2

High-throughput

0.479

High

1068014

PDK1
[Pyruvate dehydrogenase

1

3

High-throughput

0.479

High

1128183

SYAM
Alanine--tRNA ligase, mitochondrial

1

4

High-throughput

0.479

High

1152894

MRM1
rRNA methyltransferase 1, mitochondrial

1

3

High-throughput

0.479

High

1157944

RUSD3
Mitochondrial mRNA pseudouridine synthase RPUSD3

1

2

High-throughput

0.479

High

1183939

DHX30
ATP-dependent RNA helicase DHX30

1

2

High-throughput

0.479

High

1232821

FAKD4
FAST kinase domain-containing protein 4

1

8

High-throughput

0.479

High

1232822

MCUR1
Mitochondrial calcium uniporter regulator 1

1

2

High-throughput

0.479

High

1232824

RUSD4
Pseudouridylate synthase RPUSD4, mitochondrial

1

2

High-throughput

0.479

High

1232827

MTEF3
Transcription termination factor 3, mitochondrial

1

2

High-throughput

0.479

High

1232830

IMP2L
Mitochondrial inner membrane protease subunit 2

1

2

High-throughput

0.479

High

1232832

TACO1
Translational activator of cytochrome c oxidase 1

1

3

High-throughput

0.479

High

1232833

TR61B
tRNA

1

2

High-throughput

0.479

High

1232834

HINT2
Adenosine 5'-monophosphoramidase HINT2

1

5

High-throughput

0.479

High

1232835

RT26
Small ribosomal subunit protein mS26

1

2

High-throughput

0.479

High

1232836

IF3M
Translation initiation factor IF-3, mitochondrial

1

2

High-throughput

0.479

High

1232837

PARL
Presenilin-associated rhomboid-like protein, mitochondrial

1

2

High-throughput

0.479

High

1232838

MTRFR
Mitochondrial translation release factor in rescue

1

5

High-throughput

0.479

High

1232841

MET17
Ribosome assembly protein METTL17, mitochondrial

1

2

High-throughput

0.479

High

1232842

ACAD9
Complex I assembly factor ACAD9, mitochondrial

1

4

High-throughput

0.479

High

1232844

NGRN
Neugrin

1

1

High-throughput

0.479

High

1232845

DDX28
Probable ATP-dependent RNA helicase DDX28

1

2

High-throughput

0.479

High

1232846

EXD2
Exonuclease 3'-5' domain-containing protein 2

1

4

High-throughput

0.479

High

1232848

MRES1
Mitochondrial transcription rescue factor 1

1

1

High-throughput

0.479

High

1232851

RF1ML
Peptide chain release factor 1-like, mitochondrial

1

5

High-throughput

0.479

High

1183172

COX15
Heme A synthase COX15

1

0

High-throughput

0.458

High

1232823

CHCH1
Small ribosomal subunit protein mS37

1

0

High-throughput

0.458

High

1232825

TIM14
Mitochondrial import inner membrane translocase subunit TIM14

1

0

High-throughput

0.458

High

1232847

ATD3A
ATPase family AAA domain-containing protein 3A

1

5

High-throughput

0.445

High

130987

PSDE
26S proteasome non-ATPase regulatory subunit 14

1

7

High-throughput

0.437

High

329835

AGR2
Anterior gradient protein 2 homolog

1

2

High-throughput

0.437

High

347318

MYC
Myc proto-oncogene protein

1

8

High-throughput

0.437

High

824186

NR2C2
Nuclear receptor subfamily 2 group C member 2

1

3

High-throughput

0.437

High

1170799

TRI67
Tripartite motif-containing protein 67

1

11

High-throughput

0.437

High

1232840

PKHA4
Pleckstrin homology domain-containing family A member 4

1

10

High-throughput

0.437

High

1232852

ZRAN1
Ubiquitin thioesterase ZRANB1

1

4

High-throughput

0.437

High

1232854

ITM2B
Integral membrane protein 2B

1

4

High-throughput

0.407

High

1056217

I13R2
Interleukin-13 receptor subunit alpha-2

2

0

High-throughput

0.328

High

1165254

TMCO3
Transmembrane and coiled-coil domain-containing protein 3

2

0

High-throughput

0.328

High

1232819

F174A
Membrane protein FAM174A

2

0

High-throughput

0.328

High

245255

RAMP2
Receptor activity-modifying protein 2

1

0

High-throughput

0.279

Low

795373

SSRB
Translocon-associated protein subunit beta

1

0

High-throughput

0.279

Low

1203130

OSTM1
Osteopetrosis-associated transmembrane protein 1

1

0

High-throughput

0.279

Low

1224206

S22AF
Solute carrier family 22 member 15

1

0

High-throughput

0.279

Low

1232035

LRC25
Leucine-rich repeat-containing protein 25

1

0

High-throughput

0.279

Low

1232849

TMEM9
Proton-transporting V-type ATPase complex assembly regulator TMEM9

1

0

High-throughput

0.279

Low

1035502

SMAD4
Mothers against decapentaplegic homolog 4

1

0

High-throughput

0.249

Low

209263

PSCA
Prostate stem cell antigen

1

0

High-throughput

0.232

Low


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Last updated: 15 Jul 2024