Protein: FANCM
Fanconi anemia group M protein (Protein FACM) (EC 3.6.4.13) (ATP-dependent RNA helicase FANCM) (Fanconi anemia-associated polypeptide of 250 kDa) (FAAP250) (Protein Hef ortholog)

Gene: FANCM
Organism: Homo sapiens
Interactions: 71
UniProt ID: Q8IYD8

Gene Ontology (top 5):
GO:0000400 - four-way junction DNA binding
GO:0000712 - resolution of meiotic recombination intermediates
GO:0000785 - chromatin
GO:0003682 - chromatin binding
GO:0003724 - RNA helicase activity

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

1223006

FAP24
Fanconi anemia core complex-associated protein 24

11

0

Small-scale

0.934

High

1222999

CENPS
Centromere protein S

8

0

Small-scale

0.923

High

867615

BLM
RecQ-like DNA helicase BLM

5

19

Small-scale

0.915

High

67734

CENPX
Centromere protein X

5

0

Small-scale

0.875

High

1035338

TOP3A
DNA topoisomerase 3-alpha

3

6

Small-scale

0.857

High

176615

FANCA
Fanconi anemia group A protein

12

1

Small-scale

0.756

High

1222998

FANCM
Fanconi anemia group M protein

2

20

Small-scale

0.754

High

536917

TRI27
Zinc finger protein RFP

1

7

High-throughput

0.740

High

1223015

FANCL
E3 ubiquitin-protein ligase FANCL

10

0

Small-scale

0.718

High

1223012

FANCE
Fanconi anemia group E protein

8

0

Small-scale

0.713

High

174412

FANCG
Fanconi anemia group G protein

5

2

Small-scale

0.709

High

1223013

FANCF
Fanconi anemia group F protein

6

0

Small-scale

0.702

High

1223011

RMI1
RecQ-mediated genome instability protein 1

4

2

Small-scale

0.700

High

1012603

FP100
Fanconi anemia core complex-associated protein 100

6

0

Small-scale

0.695

High

517358

PCNA
Proliferating cell nuclear antigen

3

2

Small-scale

0.681

High

1223000

FANCB
Fanconi anemia group B protein

4

0

Small-scale

0.664

High

960697

FANCC
Fanconi anemia group C protein

4

0

Small-scale

0.657

High

60016

EME2
Probable crossover junction endonuclease EME2

1

2

Small-scale

0.647

High

917571

H4
Histone H4

1

15

High-throughput

0.618

High

988103

RAD51
DNA repair protein RAD51 homolog 1

1

6

Small-scale

0.618

High

1223003

EME1
Crossover junction endonuclease EME1

1

2

Small-scale

0.618

High

1223021

INO80
Chromatin-remodeling ATPase INO80

1

16

Small-scale

0.618

High

1157477

FAP20
Fanconi anemia core complex-associated protein 20

3

0

Small-scale

0.613

High

307542

EPN2
Epsin-2

2

4

High-throughput

0.606

High

395145

A4
Amyloid-beta precursor protein

2

8

High-throughput

0.602

High

1062426

PAF15
PCNA-associated factor

2

0

High-throughput

0.602

High

1223020

FBW1B
F-box/WD repeat-containing protein 11

2

20

Small-scale

0.584

High

1223004

RMI2
RecQ-mediated genome instability protein 2

2

0

Small-scale

0.569

High

331923

MOC2A
Molybdopterin synthase sulfur carrier subunit

2

0

High-throughput

0.559

High

1223023

TELO2
Telomere length regulation protein TEL2 homolog

2

0

Small-scale

0.559

High

1130304

LRRK2
Leucine-rich repeat serine/threonine-protein kinase 2

1

9

High-throughput

0.536

High

271776

PRDM1
PR domain zinc finger protein 1

1

5

High-throughput

0.536

High

1029273

MD2L1
Mitotic spindle assembly checkpoint protein MAD2A

1

5

High-throughput

0.536

High

1050927

DPYL3
Dihydropyrimidinase-related protein 3

1

1

High-throughput

0.536

High

1223001

TNR6A
Trinucleotide repeat-containing gene 6A protein

1

15

High-throughput

0.536

High

1223002

AN32B
Acidic leucine-rich nuclear phosphoprotein 32 family member B

1

6

High-throughput

0.536

High

1223005

SORT
Sortilin

1

1

High-throughput

0.536

High

1223007

KIFC3
Kinesin-like protein KIFC3

1

1

High-throughput

0.536

High

1223016

CARF
CDKN2A-interacting protein

1

7

High-throughput

0.536

High

330617

MOC2B
Molybdopterin synthase catalytic subunit

2

0

High-throughput

0.528

High

1068593

PLEC
Plectin

1

4

High-throughput

0.515

High

1049941

SPIDR
DNA repair-scaffolding protein

1

0

Small-scale

0.513

High

1223009

CAPAM
mRNA

1

0

High-throughput

0.513

High

930291

UBC9
SUMO-conjugating enzyme UBC9

1

7

Small-scale

0.501

High

428691

TRY1
Serine protease 1

1

3

High-throughput

0.489

High

933267

TBA1B
Tubulin alpha-1B chain

1

10

High-throughput

0.489

High

946565

DCD
Dermcidin

1

3

High-throughput

0.489

High

1223010

ECT2
Protein ECT2

1

5

High-throughput

0.481

High

273455

PPM1B
Protein phosphatase 1B

1

1

High-throughput

0.479

High

553148

RFA2
Replication protein A 32 kDa subunit

1

16

Small-scale

0.479

High

651649

RFA1
Replication protein A 70 kDa DNA-binding subunit

1

14

Small-scale

0.479

High

726924

FUS
RNA-binding protein FUS

1

20

High-throughput

0.479

High

749664

BRCA1
Breast cancer type 1 susceptibility protein

1

20

High-throughput

0.479

High

832573

MCM2
DNA replication licensing factor MCM2

1

20

Small-scale

0.479

High

833920

CLK2
Dual specificity protein kinase CLK2

1

15

Small-scale

0.479

High

1021057

FOXF1
Forkhead box protein F1

1

20

Small-scale

0.479

High

1184685

MCM10
Protein MCM10 homolog

1

1

Small-scale

0.479

High

1205444

ZGRF1
5'-3' DNA helicase ZGRF1

1

5

Small-scale

0.479

High

1221556

SMC5
Structural maintenance of chromosomes protein 5

1

17

High-throughput

0.479

High

1223008

FACD2
Fanconi anemia group D2 protein

1

13

High-throughput

0.479

High

1223019

MCM8
DNA helicase MCM8

1

20

Small-scale

0.479

High

1223022

FBW1A
F-box/WD repeat-containing protein 1A

1

20

Small-scale

0.479

High

264217

CDC45
Cell division control protein 45 homolog

1

0

Small-scale

0.458

High

1223014

FANCI
Fanconi anemia group I protein

1

0

Small-scale

0.458

High

1223017

ETAA1
Ewing's tumor-associated antigen 1

1

0

Small-scale

0.458

High

347287

MYC
Myc proto-oncogene protein

1

20

High-throughput

0.445

High

1043449

CUL4B
Cullin-4B

1

20

Small-scale

0.445

High

1223018

GRHL1
Grainyhead-like protein 1 homolog

1

7

High-throughput

0.445

High

1101692

KIZ
Centrosomal protein kizuna

1

0

High-throughput

0.279

Low

495730

COX5B
Cytochrome c oxidase subunit 5B, mitochondrial

1

0

High-throughput

0.269

Low


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Last updated: 15 Jul 2024