Protein: EDN3
Endothelin-3 (ET-3) (Preproendothelin-3) (PPET3)

Gene: EDN3
Organism: Homo sapiens
Interactions: 102
UniProt ID: P14138

Gene Ontology (top 5):
GO:0001755 - neural crest cell migration
GO:0002690 - positive regulation of leukocyte chemotaxis
GO:0003100 - regulation of systemic arterial blood pressure by endothelin
GO:0005102 - signaling receptor binding
GO:0005179 - hormone activity

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

535619

EDNRB
Endothelin receptor type B

1

2

Small-scale

0.647

High

129684

AGRIN
Agrin [Cleaved into: Agrin N-terminal 110 kDa subunit; Agrin C-terminal 110 kDa subunit; Agrin C-terminal 90 kDa fragment

1

4

High-throughput

0.536

High

172641

LAMA5
Laminin subunit alpha-5

1

6

High-throughput

0.536

High

258291

LRP5
Low-density lipoprotein receptor-related protein 5

1

3

High-throughput

0.536

High

270258

LRP6
Low-density lipoprotein receptor-related protein 6

1

3

High-throughput

0.536

High

276919

ATRN
Attractin

1

6

High-throughput

0.536

High

312845

GDF11
Growth/differentiation factor 11

1

1

High-throughput

0.536

High

313614

TNF6B
Tumor necrosis factor receptor superfamily member 6B

1

1

High-throughput

0.536

High

351243

TGFB1
Transforming growth factor beta-1 proprotein [Cleaved into: Latency-associated peptide

1

1

High-throughput

0.536

High

394043

A4
Amyloid-beta precursor protein

1

1

High-throughput

0.536

High

423070

PROS
Vitamin K-dependent protein S

1

4

High-throughput

0.536

High

427996

TBB5
Tubulin beta chain

1

1

High-throughput

0.536

High

437663

BGLR
Beta-glucuronidase

1

1

High-throughput

0.536

High

517916

CO6A1

1

1

High-throughput

0.536

High

517984

CO6A2

1

1

High-throughput

0.536

High

535615

ARSA
Arylsulfatase A

1

1

High-throughput

0.536

High

535617

FGFR4
Fibroblast growth factor receptor 4

1

1

High-throughput

0.536

High

535618

FGFR3
Fibroblast growth factor receptor 3

1

1

High-throughput

0.536

High

535620

PCSK6
Proprotein convertase subtilisin/kexin type 6

1

2

High-throughput

0.536

High

535622

NOTC1
Neurogenic locus notch homolog protein 1

1

2

High-throughput

0.536

High

535624

LAMB2
Laminin subunit beta-2

1

4

High-throughput

0.536

High

535625

TBA4A
Tubulin alpha-4A chain

1

3

High-throughput

0.536

High

535626

CNTP1
Contactin-associated protein 1

1

5

High-throughput

0.536

High

535627

PGBM
Basement membrane-specific heparan sulfate proteoglycan core protein

1

2

High-throughput

0.536

High

535630

NOTC2
Neurogenic locus notch homolog protein 2

1

2

High-throughput

0.536

High

535632

SEM3B
Semaphorin-3B

1

1

High-throughput

0.536

High

535633

ADA15
Disintegrin and metalloproteinase domain-containing protein 15

1

1

High-throughput

0.536

High

535634

TBB3
Tubulin beta-3 chain

1

1

High-throughput

0.536

High

535636

LAMB3
Laminin subunit beta-3

1

4

High-throughput

0.536

High

535637

GAS6
Growth arrest-specific protein 6

1

5

High-throughput

0.536

High

535649

ARSK
Arylsulfatase K

1

1

High-throughput

0.536

High

535650

CREL2
Protein disulfide isomerase CRELD2

1

2

High-throughput

0.536

High

535654

MEGF8
Multiple epidermal growth factor-like domains protein 8

1

7

High-throughput

0.536

High

535661

VWDE
von Willebrand factor D and EGF domain-containing protein

1

4

High-throughput

0.536

High

535663

PCSK9
Proprotein convertase subtilisin/kexin type 9

1

1

High-throughput

0.536

High

535667

SORL
Sortilin-related receptor

1

3

High-throughput

0.536

High

535680

CHRD
Chordin

1

3

High-throughput

0.536

High

535688

ATS7
A disintegrin and metalloproteinase with thrombospondin motifs 7

1

1

High-throughput

0.536

High

60288

POTEF
POTE ankyrin domain family member F

1

0

High-throughput

0.513

High

327259

NOE2
Noelin-2

1

0

High-throughput

0.513

High

441600

TRFM
Melanotransferrin

1

0

High-throughput

0.513

High

528069

BMP1
Bone morphogenetic protein 1

1

0

High-throughput

0.513

High

535621

ACHA5
Neuronal acetylcholine receptor subunit alpha-5

1

0

High-throughput

0.513

High

535628

DIAC
Di-N-acetylchitobiase

1

0

High-throughput

0.513

High

535640

PRSS8
Prostasin

1

0

High-throughput

0.513

High

535641

TECT1
Tectonic-1

1

0

High-throughput

0.513

High

535658

CILP2
Cartilage intermediate layer protein 2

1

0

High-throughput

0.513

High

535671

RSPRY
RING finger and SPRY domain-containing protein 1

1

0

High-throughput

0.513

High

535672

TRI11
E3 ubiquitin-protein ligase TRIM11

1

0

High-throughput

0.513

High

535673

I17RA
Interleukin-17 receptor A

1

0

High-throughput

0.513

High

535687

METRN
Meteorin

1

0

High-throughput

0.513

High

535691

LOXL2
Lysyl oxidase homolog 2

1

0

High-throughput

0.513

High

129462

MANBA
Beta-mannosidase

1

1

High-throughput

0.489

High

152073

TOR1B
Torsin-1B

1

1

High-throughput

0.489

High

351044

LDLR
Low-density lipoprotein receptor

1

3

High-throughput

0.489

High

535631

APLP2
Amyloid beta precursor like protein 2

1

1

High-throughput

0.489

High

535644

ZNG1C
Zinc-regulated GTPase metalloprotein activator 1C

1

1

High-throughput

0.489

High

535651

DUSTY
Dual serine/threonine and tyrosine protein kinase

1

1

High-throughput

0.489

High

535652

THSD4
Thrombospondin type-1 domain-containing protein 4

1

1

High-throughput

0.489

High

535653

TBA1A
Tubulin alpha-1A chain

1

3

High-throughput

0.489

High

535656

ANR46
Ankyrin repeat domain-containing protein 46

1

1

High-throughput

0.489

High

535659

P3H3
Prolyl 3-hydroxylase 3

1

1

High-throughput

0.489

High

535665

KREM2
Kremen protein 2

1

1

High-throughput

0.489

High

535668

SC65
Endoplasmic reticulum protein SC65

1

1

High-throughput

0.489

High

535676

TBA1C
Tubulin alpha-1C chain

1

3

High-throughput

0.489

High

535677

CSTN3
Calsyntenin-3

1

1

High-throughput

0.489

High

535678

ZNG1A
Zinc-regulated GTPase metalloprotein activator 1A

1

1

High-throughput

0.489

High

535681

TOR3A
Torsin-3A

1

1

High-throughput

0.489

High

535682

TBB1
Tubulin beta-1 chain

1

3

High-throughput

0.489

High

535689

JAG2
Protein jagged-2

1

2

High-throughput

0.489

High

535683

SEM4B
Semaphorin-4B

1

1

High-throughput

0.445

High

150352

ZN195
Zinc finger protein 195

1

0

High-throughput

0.279

Low

225291

H6ST1
Heparan-sulfate 6-O-sulfotransferase 1

1

0

High-throughput

0.279

Low

230115

MGRN1
E3 ubiquitin-protein ligase MGRN1

1

0

High-throughput

0.279

Low

335238

DYR
Dihydrofolate reductase

1

0

High-throughput

0.279

Low

535616

NAGAB
Alpha-N-acetylgalactosaminidase

1

0

High-throughput

0.279

Low

535623

ANAG
Alpha-N-acetylglucosaminidase

1

0

High-throughput

0.279

Low

535629

NAAA
N-acylethanolamine-hydrolyzing acid amidase

1

0

High-throughput

0.279

Low

535635

ITA7
Integrin alpha-7 [Cleaved into: Integrin alpha-7 heavy chain; Integrin alpha-7 light chain; Integrin alpha-7 70 kDa form]

1

0

High-throughput

0.279

Low

535638

CND1
Condensin complex subunit 1

1

0

High-throughput

0.279

Low

535639

OZF
Zinc finger protein OZF

1

0

High-throughput

0.279

Low

535642

FUT11
Alpha-(1,3)-fucosyltransferase 11

1

0

High-throughput

0.279

Low

535643

TGO1
Transport and Golgi organization protein 1 homolog

1

0

High-throughput

0.279

Low

535645

GT253
Inactive glycosyltransferase 25 family member 3

1

0

High-throughput

0.279

Low

535646

AB17B
Alpha/beta hydrolase domain-containing protein 17B

1

0

High-throughput

0.279

Low

535647

GLT18
Polypeptide N-acetylgalactosaminyltransferase 18

1

0

High-throughput

0.279

Low

535648

PLGT2
Protein O-glucosyltransferase 2

1

0

High-throughput

0.279

Low

535655

OAF
Out at first protein homolog

1

0

High-throughput

0.279

Low

535657

FBX11
F-box only protein 11

1

0

High-throughput

0.279

Low

535660

TRM44
Probable tRNA

1

0

High-throughput

0.279

Low

535662

SUMF1
Formylglycine-generating enzyme

1

0

High-throughput

0.279

Low

535664

UXS1
UDP-glucuronic acid decarboxylase 1

1

0

High-throughput

0.279

Low

535666

NEK9
Serine/threonine-protein kinase Nek9

1

0

High-throughput

0.279

Low

535669

N42L2
NEDD4-binding protein 2-like 2

1

0

High-throughput

0.279

Low

535670

EXT2
Exostosin-2

1

0

High-throughput

0.279

Low

535674

DDX11
ATP-dependent DNA helicase DDX11

1

0

High-throughput

0.279

Low

535675

RBM14
RNA-binding protein 14

1

0

High-throughput

0.279

Low

535679

EDEM2
ER degradation-enhancing alpha-mannosidase-like protein 2

1

0

High-throughput

0.279

Low

535684

CELR1
Cadherin EGF LAG seven-pass G-type receptor 1

1

0

High-throughput

0.279

Low

535685

SELN
Selenoprotein N

1

0

High-throughput

0.279

Low

535686

SUN2
SUN domain-containing protein 2

1

0

High-throughput

0.279

Low

535690

MA2B2
Epididymis-specific alpha-mannosidase

1

0

High-throughput

0.279

Low


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Last updated: 15 Jul 2024