Protein: AK1A1
Aldo-keto reductase family 1 member A1 (EC 1.1.1.2) (EC 1.1.1.372) (EC 1.1.1.54) (Alcohol dehydrogenase [NADP(+)]) (Aldehyde reductase) (Glucuronate reductase) (EC 1.1.1.19) (Glucuronolactone reductase) (EC 1.1.1.20) (S-nitroso-CoA reductase) (ScorR) (EC 1.6.-.-)

Gene: AK1A1, AKR1A1
Organism: Homo sapiens
Interactions: 35
UniProt ID: P14550

Gene Ontology (top 5):
GO:0004032 - aldose reductase (NADPH) activity
GO:0004033 - aldo-keto reductase (NADPH) activity
GO:0005615 - extracellular space
GO:0005829 - cytosol
GO:0006629 - lipid metabolic process

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

537531

ALDR
Aldo-keto reductase family 1 member B1

1

13

High-throughput

0.691

High

261072

SH3L1
Adapter SH3BGRL

2

4

High-throughput

0.571

High

537539

CAV1
Caveolin-1

2

0

High-throughput

0.547

High

60289

POTEF
POTE ankyrin domain family member F

1

2

High-throughput

0.536

High

537542

TRIPC
E3 ubiquitin-protein ligase TRIP12

1

1

High-throughput

0.536

High

537552

TE2IP
Telomeric repeat-binding factor 2-interacting protein 1

1

1

High-throughput

0.518

High

537537

5HT6R
5-hydroxytryptamine receptor 6

1

0

High-throughput

0.518

High

537554

M4K5
Mitogen-activated protein kinase kinase kinase kinase 5

1

0

High-throughput

0.513

High

537555

SAR1B
Small COPII coat GTPase SAR1B

1

0

High-throughput

0.513

High

537550

EXOS4
Exosome complex component RRP41

1

1

High-throughput

0.508

High

537540

AAPK1
5'-AMP-activated protein kinase catalytic subunit alpha-1

1

0

High-throughput

0.493

High

281529

WFS1
Wolframin

1

0

High-throughput

0.493

High

537535

HD
Huntingtin

1

0

High-throughput

0.493

High

537547

TOPK
Lymphokine-activated killer T-cell-originated protein kinase

1

1

High-throughput

0.489

High

537549

S2532
Solute carrier family 25 member 32

1

1

High-throughput

0.489

High

226416

PRKN
E3 ubiquitin-protein ligase parkin

1

4

High-throughput

0.479

High

537536

SOX2
Transcription factor SOX-2

1

1

High-throughput

0.479

High

537545

NUP43
Nucleoporin Nup43

1

1

High-throughput

0.479

High

537546

BAP1
Ubiquitin carboxyl-terminal hydrolase BAP1

1

5

High-throughput

0.479

High

537553

ZRAN1
Ubiquitin thioesterase ZRANB1

1

4

High-throughput

0.479

High

148348

CTRO
Citron Rho-interacting kinase

1

0

High-throughput

0.458

High

353754

IGHG2
Immunoglobulin heavy constant gamma 2

1

0

High-throughput

0.458

High

503357

HSP7C
Heat shock cognate 71 kDa protein

1

0

High-throughput

0.458

High

537551

ANLN
Anillin

1

0

High-throughput

0.458

High

496213

TAU
Microtubule-associated protein tau

1

3

High-throughput

0.445

High

537532

RFA2
Replication protein A 32 kDa subunit

1

1

High-throughput

0.437

High

537533

RFA1
Replication protein A 70 kDa DNA-binding subunit

1

1

High-throughput

0.437

High

537534

RFA3
Replication protein A 14 kDa subunit

1

1

High-throughput

0.437

High

537541

DYR1A
Dual specificity tyrosine-phosphorylation-regulated kinase 1A

1

4

High-throughput

0.437

High

537544

TRI67
Tripartite motif-containing protein 67

1

2

High-throughput

0.437

High

537548

ZDHC5
Palmitoyltransferase ZDHHC5

1

2

High-throughput

0.407

High

537538

TERF1
Telomeric repeat-binding factor 1

1

0

High-throughput

0.282

High

177122

MOT5
Monocarboxylate transporter 5

1

0

High-throughput

0.269

Low

309775

MRP6
ATP-binding cassette sub-family C member 6

1

0

Small-scale

0.249

Low

537543

TET5C
Terminal nucleotidyltransferase 5C

1

0

High-throughput

0.249

Low


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Last updated: 15 Jul 2024