Protein: NAAA
N-acylethanolamine-hydrolyzing acid amidase (EC 3.5.1.60) (Acid ceramidase-like protein) (Acylsphingosine deacylase NAAA) (EC 3.5.1.23) (N-acylsphingosine amidohydrolase-like) (ASAH-like protein) [Cleaved into: N-acylethanolamine-hydrolyzing acid amidase subunit alpha; N-acylethanolamine-hydrolyzing acid amidase subunit beta]

Gene: NAAA
Organism: Homo sapiens
Interactions: 219
UniProt ID: Q02083

Gene Ontology (top 5):
GO:0005737 - cytoplasm
GO:0005764 - lysosome
GO:0006631 - fatty acid metabolic process
GO:0006670 - sphingosine metabolic process
GO:0016020 - membrane

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

234428

NRP2
Neuropilin-2

3

2

High-throughput

0.667

High

530630

ITA4
Integrin alpha-4

3

3

High-throughput

0.667

High

550462

ARSB
Arylsulfatase B

3

6

High-throughput

0.667

High

709245

GALNS
N-acetylgalactosamine-6-sulfatase

3

6

High-throughput

0.667

High

968837

TBB8
Tubulin beta-8 chain

3

3

High-throughput

0.667

High

968859

ARSK
Arylsulfatase K

3

6

High-throughput

0.667

High

968891

PCSK5
Proprotein convertase subtilisin/kexin type 5

3

1

High-throughput

0.667

High

968914

CNTP3
Contactin-associated protein-like 3

3

2

High-throughput

0.667

High

968941

CEIP2
Inactive cell surface hyaluronidase CEMIP2

3

1

High-throughput

0.667

High

968950

MA2B2
Epididymis-specific alpha-mannosidase

3

2

High-throughput

0.667

High

238793

UGDH
UDP-glucose 6-dehydrogenase

3

0

High-throughput

0.638

High

872931

ANAG
Alpha-N-acetylglucosaminidase

3

0

High-throughput

0.638

High

968835

T132A
Transmembrane protein 132A

3

0

High-throughput

0.638

High

968865

SYVN1
E3 ubiquitin-protein ligase synoviolin

3

0

High-throughput

0.638

High

968942

NB5R1
NADH-cytochrome b5 reductase 1

3

0

High-throughput

0.638

High

419193

ITAV
Integrin alpha-V

2

3

High-throughput

0.628

High

933407

TBA4A
Tubulin alpha-4A chain

2

3

High-throughput

0.628

High

849834

SPHM
N-sulphoglucosamine sulphohydrolase

2

6

High-throughput

0.611

High

968861

TBA1A
Tubulin alpha-1A chain

2

3

High-throughput

0.611

High

968912

EDEM2
ER degradation-enhancing alpha-mannosidase-like protein 2

2

2

High-throughput

0.611

High

840368

ERF
ETS domain-containing transcription factor ERF

3

1

High-throughput

0.609

High

968826

OS9
Protein OS-9

3

1

High-throughput

0.609

High

968875

PGLT1
Protein O-glucosyltransferase 1

3

2

High-throughput

0.609

High

968888

EDEM1
ER degradation-enhancing alpha-mannosidase-like protein 1

3

2

High-throughput

0.609

High

968904

DCBD2
Discoidin, CUB and LCCL domain-containing protein 2

3

5

High-throughput

0.609

High

260229

ENTP6
Ectonucleoside triphosphate diphosphohydrolase 6

2

0

High-throughput

0.585

High

968894

TTC17
Tetratricopeptide repeat protein 17

2

0

High-throughput

0.585

High

968922

SIAE
Sialate O-acetylesterase

2

0

High-throughput

0.585

High

968923

S38AA
Solute carrier family 38 member 10

2

0

High-throughput

0.585

High

968870

SULF2
Extracellular sulfatase Sulf-2

2

6

High-throughput

0.558

High

60325

POTEF
POTE ankyrin domain family member F

1

1

High-throughput

0.536

High

199451

SPIT1
Kunitz-type protease inhibitor 1

1

1

High-throughput

0.536

High

211360

PI15
Peptidase inhibitor 15

1

1

High-throughput

0.536

High

274528

S2512
Electrogenic aspartate/glutamate antiporter SLC25A12, mitochondrial

1

4

High-throughput

0.536

High

355027

DQB1
HLA class II histocompatibility antigen, DQ beta 1 chain

1

2

High-throughput

0.536

High

381168

TBB4A
Tubulin beta-4A chain

1

3

High-throughput

0.536

High

400051

ICAM1
Intercellular adhesion molecule 1

1

1

High-throughput

0.536

High

423078

PROS
Vitamin K-dependent protein S

1

2

High-throughput

0.536

High

428147

TBB5
Tubulin beta chain

1

3

High-throughput

0.536

High

488194

HLAC
HLA class I histocompatibility antigen, C alpha chain

1

2

High-throughput

0.536

High

501991

BIP
Endoplasmic reticulum chaperone BiP

1

1

High-throughput

0.536

High

514823

MPRI
Cation-independent mannose-6-phosphate receptor

1

2

High-throughput

0.536

High

518123

ADT1
ADP/ATP translocase 1

1

2

High-throughput

0.536

High

518319

ADT3
ADP/ATP translocase 3

1

3

High-throughput

0.536

High

530871

AT1A3
Sodium/potassium-transporting ATPase subunit alpha-3

1

1

High-throughput

0.536

High

546604

ARSA
Arylsulfatase A

1

6

High-throughput

0.536

High

606877

IDS
Iduronate 2-sulfatase

1

6

High-throughput

0.536

High

673952

HLAF
HLA class I histocompatibility antigen, alpha chain F

1

2

High-throughput

0.536

High

958283

AT2C1
Calcium-transporting ATPase type 2C member 1

1

1

High-throughput

0.536

High

959187

S25A3
Solute carrier family 25 member 3

1

6

High-throughput

0.536

High

964639

IL5RA
Interleukin-5 receptor subunit alpha

1

1

High-throughput

0.536

High

968822

MFGM
Lactadherin

1

4

High-throughput

0.536

High

968827

TBB3
Tubulin beta-3 chain

1

3

High-throughput

0.536

High

968830

DPOD3
DNA polymerase delta subunit 3

1

1

High-throughput

0.536

High

968836

TECT1
Tectonic-1

1

1

High-throughput

0.536

High

968847

GP107
Protein GPR107

1

1

High-throughput

0.536

High

968850

DRS7B
Dehydrogenase/reductase SDR family member 7B

1

1

High-throughput

0.536

High

968851

ACD10
Acyl-CoA dehydrogenase family member 10

1

1

High-throughput

0.536

High

968855

POTEE
POTE ankyrin domain family member E

1

1

High-throughput

0.536

High

968887

PMGT1
Protein O-linked-mannose beta-1,2-N-acetylglucosaminyltransferase 1

1

1

High-throughput

0.536

High

968906

YMEL1
ATP-dependent zinc metalloprotease YME1L1

1

1

High-throughput

0.536

High

968909

TBA1C
Tubulin alpha-1C chain

1

3

High-throughput

0.536

High

968918

TBB1
Tubulin beta-1 chain

1

4

High-throughput

0.536

High

968931

PYRG2
CTP synthase 2

1

1

High-throughput

0.536

High

968945

FBX2
F-box only protein 2

1

2

High-throughput

0.536

High

968946

MA1B1
Endoplasmic reticulum mannosyl-oligosaccharide 1,2-alpha-mannosidase

1

2

High-throughput

0.536

High

968955

ORNT1
Mitochondrial ornithine transporter 1

1

6

High-throughput

0.536

High

126797

ACATN
Acetyl-coenzyme A transporter 1

1

0

High-throughput

0.513

High

152275

ADA10
Disintegrin and metalloproteinase domain-containing protein 10

1

0

High-throughput

0.513

High

153302

CDIPT
CDP-diacylglycerol--inositol 3-phosphatidyltransferase

1

0

High-throughput

0.513

High

157560

MGST3
Glutathione S-transferase 3, mitochondrial

1

0

High-throughput

0.513

High

200382

HS12A
Heat shock 70 kDa protein 12A

1

0

High-throughput

0.513

High

239262

ICMT
Protein-S-isoprenylcysteine O-methyltransferase

1

0

High-throughput

0.513

High

242432

DKC1
H/ACA ribonucleoprotein complex subunit DKC1

1

0

High-throughput

0.513

High

260186

MPU1
Mannose-P-dolichol utilization defect 1 protein

1

0

High-throughput

0.513

High

318476

CDS2
Phosphatidate cytidylyltransferase 2

1

0

High-throughput

0.513

High

513569

PYC
Pyruvate carboxylase, mitochondrial

1

0

High-throughput

0.513

High

532929

PRG2
Bone marrow proteoglycan

1

0

High-throughput

0.513

High

556434

ITB4
Integrin beta-4

1

0

High-throughput

0.513

High

563878

NAGAB
Alpha-N-acetylgalactosaminidase

1

0

High-throughput

0.513

High

621204

KTHY
Thymidylate kinase

1

0

High-throughput

0.513

High

640717

CTNA2
Catenin alpha-2

1

0

High-throughput

0.513

High

708215

ERD22
ER lumen protein-retaining receptor 2

1

0

High-throughput

0.513

High

723764

IDUA
Alpha-L-iduronidase

1

0

High-throughput

0.513

High

834268

PSN1
Presenilin-1

1

0

High-throughput

0.513

High

848347

IRAK1
Interleukin-1 receptor-associated kinase 1

1

0

High-throughput

0.513

High

957392

IDD
Integral membrane protein DGCR2/IDD

1

0

High-throughput

0.513

High

964299

RUNX1
Runt-related transcription factor 1

1

0

High-throughput

0.513

High

968820

UPAR
Urokinase plasminogen activator surface receptor

1

0

High-throughput

0.513

High

968823

SIA4C
CMP-N-acetylneuraminate-beta-galactosamide-alpha-2,3-sialyltransferase 4

1

0

High-throughput

0.513

High

968831

NOMO1
BOS complex subunit NOMO1

1

0

High-throughput

0.513

High

968840

OCAD2
OCIA domain-containing protein 2

1

0

High-throughput

0.513

High

968848

KANK2
KN motif and ankyrin repeat domain-containing protein 2

1

0

High-throughput

0.513

High

968849

IQEC1
IQ motif and SEC7 domain-containing protein 1

1

0

High-throughput

0.513

High

968858

ENPP7
Ectonucleotide pyrophosphatase/phosphodiesterase family member 7

1

0

High-throughput

0.513

High

968860

NFXL1
NF-X1-type zinc finger protein NFXL1

1

0

High-throughput

0.513

High

968862

RD3
Protein RD3

1

0

High-throughput

0.513

High

968864

AGRG6
Adhesion G-protein coupled receptor G6

1

0

High-throughput

0.513

High

968872

S11IP
Serine/threonine-protein kinase 11-interacting protein

1

0

High-throughput

0.513

High

968878

NLGN2
Neuroligin-2

1

0

High-throughput

0.513

High

968879

COQ8A
Atypical kinase COQ8A, mitochondrial

1

0

High-throughput

0.513

High

968885

TM263
Transmembrane protein 263

1

0

High-throughput

0.513

High

968890

GGH
Gamma-glutamyl hydrolase

1

0

High-throughput

0.513

High

968893

CCD47
PAT complex subunit CCDC47

1

0

High-throughput

0.513

High

968896

RUSF1
RUS family member 1

1

0

High-throughput

0.513

High

968899

S35E1
Solute carrier family 35 member E1

1

0

High-throughput

0.513

High

968902

F210A
Protein FAM210A

1

0

High-throughput

0.513

High

968905

TM209
Transmembrane protein 209

1

0

High-throughput

0.513

High

968907

RMD3
Regulator of microtubule dynamics protein 3

1

0

High-throughput

0.513

High

968908

PKP2
Plakophilin-2

1

0

High-throughput

0.513

High

968915

LMA2L
VIP36-like protein

1

0

High-throughput

0.513

High

968921

L2HDH
L-2-hydroxyglutarate dehydrogenase, mitochondrial

1

0

High-throughput

0.513

High

968925

SDF2L
Stromal cell-derived factor 2-like protein 1

1

0

High-throughput

0.513

High

968926

SEC12
Guanine nucleotide-exchange factor SEC12

1

0

High-throughput

0.513

High

968934

DJB12
DnaJ homolog subfamily B member 12

1

0

High-throughput

0.513

High

968936

CHPF2
Chondroitin sulfate glucuronyltransferase

1

0

High-throughput

0.513

High

968940

SUSD2
Sushi domain-containing protein 2

1

0

High-throughput

0.513

High

968948

XCT
Cystine/glutamate transporter

1

0

High-throughput

0.513

High

968952

SAM50
Sorting and assembly machinery component 50 homolog

1

0

High-throughput

0.513

High

968953

PCDB3
Protocadherin beta-3

1

0

High-throughput

0.513

High

968956

TAF6L
TAF6-like RNA polymerase II p300/CBP-associated factor-associated factor 65 kDa subunit 6L

1

0

High-throughput

0.513

High

968958

S23IP
SEC23-interacting protein

1

0

High-throughput

0.513

High

394559

A4
Amyloid-beta precursor protein

1

1

High-throughput

0.501

High

561299

CRIS2
Cysteine-rich secretory protein 2

1

1

High-throughput

0.489

High

566876

ITA2
Integrin alpha-2

1

3

High-throughput

0.489

High

781166

ETV3
ETS translocation variant 3

1

1

High-throughput

0.489

High

830071

MA2A2
Alpha-mannosidase 2x

1

2

High-throughput

0.489

High

968819

BDH
D-beta-hydroxybutyrate dehydrogenase, mitochondrial

1

1

High-throughput

0.489

High

968828

ITA7
Integrin alpha-7 [Cleaved into: Integrin alpha-7 heavy chain; Integrin alpha-7 light chain; Integrin alpha-7 70 kDa form]

1

3

High-throughput

0.489

High

968829

MBTP1
Membrane-bound transcription factor site-1 protease

1

1

High-throughput

0.489

High

968852

SCMC2
Mitochondrial adenyl nucleotide antiporter SLC25A25

1

4

High-throughput

0.489

High

968853

SFXN4
Sideroflexin-4

1

2

High-throughput

0.489

High

968856

PLGT2
Protein O-glucosyltransferase 2

1

2

High-throughput

0.489

High

968863

PLGT3
Protein O-glucosyltransferase 3

1

2

High-throughput

0.489

High

968873

S2529
Mitochondrial basic amino acids transporter

1

5

High-throughput

0.489

High

968876

TM87A
Transmembrane protein 87A

1

1

High-throughput

0.489

High

968882

S2540
Mitochondrial glutathione transporter SLC25A40

1

5

High-throughput

0.489

High

968895

ERLEC
Endoplasmic reticulum lectin 1

1

1

High-throughput

0.489

High

968901

SFXN2
Sideroflexin-2

1

2

High-throughput

0.489

High

968913

SFXN3
Sideroflexin-3

1

2

High-throughput

0.489

High

968924

TPC
Mitochondrial thiamine pyrophosphate carrier

1

4

High-throughput

0.489

High

968933

RNF12
E3 ubiquitin-protein ligase RLIM

1

2

High-throughput

0.489

High

968939

DIC
Mitochondrial dicarboxylate carrier

1

4

High-throughput

0.489

High

968943

BTNL2
Butyrophilin-like protein 2

1

1

High-throughput

0.489

High

968949

SPG7
Mitochondrial inner membrane m-AAA protease component paraplegin

1

1

High-throughput

0.489

High

968834

MA2A1
Alpha-mannosidase 2

1

2

High-throughput

0.479

High

968897

TECT2
Tectonic-2

1

1

High-throughput

0.479

High

968930

FBX6
F-box only protein 6

1

2

High-throughput

0.479

High

267231

CLN5
Bis(monoacylglycero)phosphate synthase CLN5

1

0

High-throughput

0.458

High

968884

SCRB1
Scavenger receptor class B member 1

1

0

High-throughput

0.458

High

968929

CHSTC
Carbohydrate sulfotransferase 12

1

0

High-throughput

0.458

High

382394

HLAA
HLA class I histocompatibility antigen, A alpha chain

1

2

High-throughput

0.445

High

968903

CNT3B
Contactin-associated protein-like 3B

1

2

High-throughput

0.445

High

205286

TGON2
Trans-Golgi network integral membrane protein 2

1

1

High-throughput

0.437

High

209226

PSCA
Prostate stem cell antigen

1

0

High-throughput

0.426

High

574197

BMP7
Bone morphogenetic protein 7

3

0

High-throughput

0.347

High

856902

NDST1
Bifunctional heparan sulfate N-deacetylase/N-sulfotransferase 1

3

0

High-throughput

0.347

High

968832

EXT1
Exostosin-1

3

0

High-throughput

0.347

High

968838

FUT11
Alpha-(1,3)-fucosyltransferase 11

3

0

High-throughput

0.347

High

968846

MANEL
Glycoprotein endo-alpha-1,2-mannosidase-like protein

3

0

High-throughput

0.347

High

968866

OAF
Out at first protein homolog

3

0

High-throughput

0.347

High

305301

NXPH4
Neurexophilin-4

2

0

High-throughput

0.318

High

874435

PLTP
Phospholipid transfer protein

2

0

High-throughput

0.318

High

118278

HAX1
HCLS1-associated protein X-1

1

0

High-throughput

0.279

Low

150363

ZN195
Zinc finger protein 195

1

0

High-throughput

0.279

Low

265765

CRLF1
Cytokine receptor-like factor 1

1

0

High-throughput

0.279

Low

319539

LY86
Lymphocyte antigen 86

1

0

High-throughput

0.279

Low

362523

C1QB
Complement C1q subcomponent subunit B

1

0

High-throughput

0.279

Low

389453

REL1
Prorelaxin H1 [Cleaved into: Relaxin B chain; Relaxin A chain]

1

0

High-throughput

0.279

Low

398513

PPB1
Alkaline phosphatase, placental type

1

0

High-throughput

0.279

Low

535629

EDN3
Endothelin-3

1

0

High-throughput

0.279

Low

838563

PPOX
Protoporphyrinogen oxidase

1

0

High-throughput

0.279

Low

875823

MFAP4
Microfibril-associated glycoprotein 4

1

0

High-throughput

0.279

Low

882719

STX17
Syntaxin-17

1

0

High-throughput

0.279

Low

947922

RT11
Small ribosomal subunit protein uS11m

1

0

High-throughput

0.279

Low

968821

RON
Macrophage-stimulating protein receptor

1

0

High-throughput

0.279

Low

968824

SEM3B
Semaphorin-3B

1

0

High-throughput

0.279

Low

968825

SG2A2
Mammaglobin-A

1

0

High-throughput

0.279

Low

968833

TAZ
Tafazzin

1

0

High-throughput

0.279

Low

968839

FAKD1
FAST kinase domain-containing protein 1, mitochondrial

1

0

High-throughput

0.279

Low

968841

SYEM
Nondiscriminating glutamyl-tRNA synthetase EARS2, mitochondrial

1

0

High-throughput

0.279

Low

968843

COX20
Cytochrome c oxidase assembly protein COX20, mitochondrial

1

0

High-throughput

0.279

Low

968844

SYRM
Probable arginine--tRNA ligase, mitochondrial

1

0

High-throughput

0.279

Low

968845

GT253
Inactive glycosyltransferase 25 family member 3

1

0

High-throughput

0.279

Low

968857

LYZL1
Lysozyme-like protein 1

1

0

High-throughput

0.279

Low

968867

MISP
Mitotic interactor and substrate of PLK1

1

0

High-throughput

0.279

Low

968869

FXRD2
FAD-dependent oxidoreductase domain-containing protein 2

1

0

High-throughput

0.279

Low

968871

GLT12
Polypeptide N-acetylgalactosaminyltransferase 12

1

0

High-throughput

0.279

Low

968874

SUMF1
Formylglycine-generating enzyme

1

0

High-throughput

0.279

Low

968880

FIBIN
Fin bud initiation factor homolog

1

0

High-throughput

0.279

Low

968881

NUBPL
Iron-sulfur cluster transfer protein NUBPL

1

0

High-throughput

0.279

Low

968886

CA054
Uncharacterized protein C1orf54

1

0

High-throughput

0.279

Low

968892

GCDH
Glutaryl-CoA dehydrogenase, mitochondrial

1

0

High-throughput

0.279

Low

968898

KIRR1
Kin of IRRE-like protein 1

1

0

High-throughput

0.279

Low

968900

NAR5
Ecto-ADP-ribosyltransferase 5

1

0

High-throughput

0.279

Low

968910

MIC25
MICOS complex subunit MIC25

1

0

High-throughput

0.279

Low

968911

LRFN3
Leucine-rich repeat and fibronectin type-III domain-containing protein 3

1

0

High-throughput

0.279

Low

968916

SIL1
Nucleotide exchange factor SIL1

1

0

High-throughput

0.279

Low

968917

KLK15
Kallikrein-15

1

0

High-throughput

0.279

Low

968919

SG196
Protein O-mannose kinase

1

0

High-throughput

0.279

Low

968920

ANTR1
Anthrax toxin receptor 1

1

0

High-throughput

0.279

Low

968927

TIDC1
Complex I assembly factor TIMMDC1, mitochondrial

1

0

High-throughput

0.279

Low

968928

TF7L2
Transcription factor 7-like 2

1

0

High-throughput

0.279

Low

968932

T11L1
T-complex protein 11-like protein 1

1

0

High-throughput

0.279

Low

968935

UGGG2
UDP-glucose:glycoprotein glucosyltransferase 2

1

0

High-throughput

0.279

Low

968937

FA8A1
Protein FAM8A1

1

0

High-throughput

0.279

Low

968938

SE1L1
Protein sel-1 homolog 1

1

0

High-throughput

0.279

Low

968944

GGT7
Glutathione hydrolase 7

1

0

High-throughput

0.279

Low

968947

TMCO1
Calcium load-activated calcium channel

1

0

High-throughput

0.279

Low

968951

SAMH1
Deoxynucleoside triphosphate triphosphohydrolase SAMHD1

1

0

High-throughput

0.279

Low

968954

LIPG
Endothelial lipase

1

0

High-throughput

0.279

Low

968957

SQOR
Sulfide:quinone oxidoreductase, mitochondrial

1

0

High-throughput

0.279

Low

297857

SC24D
Protein transport protein Sec24D

1

0

High-throughput

0.249

Low

968842

NHLC3
NHL repeat-containing protein 3

1

0

High-throughput

0.249

Low

968854

WDR73
WD repeat-containing protein 73

1

0

High-throughput

0.249

Low

968868

GLBL2
Beta-galactosidase-1-like protein 2

1

0

High-throughput

0.249

Low

968877

SMG8
Nonsense-mediated mRNA decay factor SMG8

1

0

High-throughput

0.249

Low

968883

ZN507
Zinc finger protein 507

1

0

High-throughput

0.249

Low

968889

SC65
Endoplasmic reticulum protein SC65

1

0

High-throughput

0.249

Low


Service provided by Combinatics, Japan

Last updated: 15 Jul 2024