Protein: MAEA
E3 ubiquitin-protein transferase MAEA (EC 2.3.2.27) (Cell proliferation-inducing gene 5 protein) (Erythroblast macrophage protein) (Human lung cancer oncogene 10 protein) (HLC-10) (Macrophage erythroblast attacher) (P44EMLP)

Gene: MAEA
Organism: Homo sapiens
Interactions: 139
UniProt ID: Q7L5Y9

Gene Ontology (top 5):
GO:0000151 - ubiquitin ligase complex
GO:0003779 - actin binding
GO:0005634 - nucleus
GO:0005654 - nucleoplasm
GO:0005737 - cytoplasm

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

1185138

RANB9
Ran-binding protein 9

8

19

Small-scale

0.969

High

1185157

RMD5A
E3 ubiquitin-protein transferase RMND5A

8

16

Small-scale

0.969

High

1185162

GID8
Glucose-induced degradation protein 8 homolog

4

16

Small-scale

0.917

High

1167148

RBP10
Ran-binding protein 10

3

17

High-throughput

0.866

High

1185129

RMD5B
E3 ubiquitin-protein transferase RMND5B

2

16

High-throughput

0.789

High

1185113

ARMC8
Armadillo repeat-containing protein 8

4

8

Small-scale

0.703

High

1185156

WDR26
WD repeat-containing protein 26

3

11

Small-scale

0.674

High

526901

TDGF1
Protein Cripto

3

5

High-throughput

0.667

High

1185167

MKLN1
Muskelin

3

6

Small-scale

0.660

High

1185110

MAEA
E3 ubiquitin-protein transferase MAEA

1

16

Small-scale

0.647

High

914869

YPEL5
Protein yippee-like 5

3

9

High-throughput

0.646

High

217035

PRIC3
Prickle planar cell polarity protein 3

2

5

High-throughput

0.628

High

1120104

TIGD5
Tigger transposable element-derived protein 5

2

3

High-throughput

0.628

High

1185134

JPH4
Junctophilin-4

2

3

High-throughput

0.628

High

1185114

GID4
Glucose-induced degradation protein 4 homolog

2

8

High-throughput

0.619

High

1028180

GPS2
G protein pathway suppressor 2

2

3

High-throughput

0.611

High

1185130

AURKB
Aurora kinase B

2

3

High-throughput

0.611

High

532992

PRG2
Bone marrow proteoglycan

3

11

High-throughput

0.609

High

764748

GDNF
Glial cell line-derived neurotrophic factor

3

3

High-throughput

0.609

High

1116924

GRPL2
GLIPR1-like protein 2

3

3

High-throughput

0.609

High

1185146

RM04
Large ribosomal subunit protein uL4m

3

5

High-throughput

0.609

High

1185145

TMM70
Transmembrane protein 70, mitochondrial

2

0

High-throughput

0.602

High

908742

UBE2H
Ubiquitin-conjugating enzyme E2 H

2

15

High-throughput

0.595

High

227881

PRKN
E3 ubiquitin-protein ligase parkin

2

5

High-throughput

0.584

High

528112

BMP1
Bone morphogenetic protein 1

2

6

High-throughput

0.574

High

1185124

PIGT
GPI transamidase component PIG-T

2

5

High-throughput

0.574

High

1185126

RM38
Large ribosomal subunit protein mL38

2

1

High-throughput

0.574

High

1185131

CC120
Coiled-coil domain-containing protein 120

2

4

High-throughput

0.574

High

1185149

PDGFD
Platelet-derived growth factor D

2

7

High-throughput

0.574

High

1185168

PRG3
Proteoglycan 3

2

11

High-throughput

0.574

High

1185170

INSL6
Insulin-like peptide INSL6

2

5

High-throughput

0.574

High

448881

MMP7
Matrilysin

2

6

High-throughput

0.558

High

1185132

SFRP2
Secreted frizzled-related protein 2

2

3

High-throughput

0.558

High

159763

LECT2
Leukocyte cell-derived chemotaxin-2

1

4

High-throughput

0.536

High

203976

HTRA2
Serine protease HTRA2, mitochondrial

1

4

High-throughput

0.536

High

238496

CST8
Cystatin-8

1

3

High-throughput

0.536

High

253987

MTG16
Protein CBFA2T3

1

4

High-throughput

0.536

High

295863

LY6H
Lymphocyte antigen 6H

1

3

High-throughput

0.536

High

351824

GLUC
Pro-glucagon [Cleaved into: Glicentin; Glicentin-related polypeptide

1

5

High-throughput

0.536

High

382607

DPB1
HLA class II histocompatibility antigen, DP beta 1 chain

1

4

High-throughput

0.536

High

398192

PERM
Myeloperoxidase

1

1

High-throughput

0.536

High

439341

CATG
Cathepsin G

1

2

High-throughput

0.536

High

474826

POTEI
POTE ankyrin domain family member I

1

2

High-throughput

0.536

High

521285

SKI
Ski oncogene

1

3

High-throughput

0.536

High

571503

DDX5
Probable ATP-dependent RNA helicase DDX5

1

3

High-throughput

0.536

High

675836

GCH1
GTP cyclohydrolase 1

1

4

High-throughput

0.536

High

818188

SOX2
Transcription factor SOX-2

1

7

High-throughput

0.536

High

980625

TLE1
Transducin-like enhancer protein 1

1

2

High-throughput

0.536

High

980942

TLE4
Transducin-like enhancer protein 4

1

2

High-throughput

0.536

High

1033670

IKZF1
DNA-binding protein Ikaros

1

2

High-throughput

0.536

High

1088016

DUS6
Dual specificity protein phosphatase 6

1

4

High-throughput

0.536

High

1167481

CRDL2
Chordin-like protein 2

1

4

High-throughput

0.536

High

1185111

RHG22
Rho GTPase-activating protein 22

1

3

High-throughput

0.536

High

1185116

ELOA2
Elongin-A2

1

1

High-throughput

0.536

High

1185120

LIRB4
Leukocyte immunoglobulin-like receptor subfamily B member 4

1

4

High-throughput

0.536

High

1185121

NEUR4
Sialidase-4

1

1

High-throughput

0.536

High

1185123

DDX17
Probable ATP-dependent RNA helicase DDX17

1

3

High-throughput

0.536

High

1185143

GDF15
Growth/differentiation factor 15

1

7

High-throughput

0.536

High

1185144

DDX50
ATP-dependent RNA helicase DDX50

1

9

High-throughput

0.536

High

1185148

UCK2
Uridine-cytidine kinase 2

1

1

High-throughput

0.536

High

1185159

SPON1
Spondin-1

1

6

High-throughput

0.536

High

1185160

EMIL3
EMILIN-3

1

5

High-throughput

0.536

High

1185165

TCAL9
Transcription elongation factor A protein-like 9

1

4

High-throughput

0.536

High

893810

S10AA
Protein S100-A10

1

4

High-throughput

0.515

High

592792

MCH
Pro-MCH [Cleaved into: Neuropeptide-glycine-glutamic acid

1

0

High-throughput

0.513

High

873556

SNAA
Alpha-soluble NSF attachment protein

1

0

High-throughput

0.513

High

1051794

IL27B
Interleukin-27 subunit beta

1

0

High-throughput

0.513

High

1185117

LYPD1
Ly6/PLAUR domain-containing protein 1

1

0

High-throughput

0.513

High

1185125

PAUF
Pancreatic adenocarcinoma up-regulated factor

1

0

High-throughput

0.513

High

1185135

CALR3
Calreticulin-3

1

0

High-throughput

0.513

High

1185139

HPLN3
Hyaluronan and proteoglycan link protein 3

1

0

High-throughput

0.513

High

1185140

CK5P1
Mitochondrial tRNA methylthiotransferase CDK5RAP1

1

0

High-throughput

0.513

High

1185147

BACH2
Transcription regulator protein BACH2

1

0

High-throughput

0.513

High

1185161

HIF1N
Hypoxia-inducible factor 1-alpha inhibitor

1

0

High-throughput

0.513

High

835427

GSK3A
Glycogen synthase kinase-3 alpha

1

1

High-throughput

0.508

High

895826

UB2D3
Ubiquitin-conjugating enzyme E2 D3

1

6

High-throughput

0.501

High

146721

NCKP5
Nck-associated protein 5

1

1

High-throughput

0.489

High

261845

NDUS6
NADH dehydrogenase [ubiquinone] iron-sulfur protein 6, mitochondrial

1

4

High-throughput

0.489

High

445948

NMB
Neuromedin-B [Cleaved into: Neuromedin-B-32; Neuromedin-B]

1

4

High-throughput

0.489

High

533606

TNNT1
Troponin T, slow skeletal muscle

1

2

High-throughput

0.489

High

611572

GNLY
Granulysin

1

5

High-throughput

0.489

High

799434

TNNT3
Troponin T, fast skeletal muscle

1

2

High-throughput

0.489

High

799570

MMP13
Collagenase 3

1

6

High-throughput

0.489

High

885208

ISK7
Serine protease inhibitor Kazal-type 7

1

1

High-throughput

0.489

High

949088

HTRA3
Serine protease HTRA3

1

4

High-throughput

0.489

High

1102590

INSY1
Inhibitory synaptic factor 1

1

1

High-throughput

0.489

High

1127549

EFHC2
EF-hand domain-containing family member C2

1

4

High-throughput

0.489

High

1185112

LCA5
Lebercilin

1

1

High-throughput

0.489

High

1185119

KCTD6
BTB/POZ domain-containing protein KCTD6

1

6

High-throughput

0.489

High

1185122

COR2A
Coronin-2A

1

3

High-throughput

0.489

High

1185127

RT24
Small ribosomal subunit protein uS3m

1

3

High-throughput

0.489

High

1185136

IL17F
Interleukin-17F

1

2

High-throughput

0.489

High

1185150

WN10A
Protein Wnt-10a

1

5

High-throughput

0.489

High

1185151

RM18
Large ribosomal subunit protein uL18m

1

5

High-throughput

0.489

High

1185164

ATS1
A disintegrin and metalloproteinase with thrombospondin motifs 1

1

6

High-throughput

0.489

High

1185166

MRM2
rRNA methyltransferase 2, mitochondrial

1

3

High-throughput

0.489

High

1185169

COQ4
Ubiquinone biosynthesis protein COQ4 homolog, mitochondrial

1

3

High-throughput

0.489

High

151059

DVL2
Segment polarity protein dishevelled homolog DVL-2

1

5

High-throughput

0.479

High

233861

HBP1
HMG box-containing protein 1

1

11

High-throughput

0.479

High

262494

TULP3
Tubby-related protein 3

1

1

High-throughput

0.479

High

294971

RECQ4
ATP-dependent DNA helicase Q4

1

10

High-throughput

0.479

High

301894

TRI37
E3 ubiquitin-protein ligase TRIM37

1

4

High-throughput

0.479

High

475968

UBC
Polyubiquitin-C [Cleaved into: Ubiquitin]

1

1

High-throughput

0.479

High

714549

GRK5
G protein-coupled receptor kinase 5

1

2

High-throughput

0.479

High

717186

CTNB1
Catenin beta-1

1

2

Small-scale

0.479

High

894753

RAB8A
Ras-related protein Rab-8A

1

5

High-throughput

0.479

High

1029568

TIF1B
Transcription intermediary factor 1-beta

1

1

Small-scale

0.479

High

1041898

CUL3
Cullin-3

1

5

High-throughput

0.479

High

1049072

TRI14
Tripartite motif-containing protein 14

1

2

High-throughput

0.479

High

1076888

PTN14
Tyrosine-protein phosphatase non-receptor type 14

1

10

High-throughput

0.479

High

1087908

PTN21
Tyrosine-protein phosphatase non-receptor type 21

1

10

High-throughput

0.479

High

1170554

TRI67
Tripartite motif-containing protein 67

1

5

High-throughput

0.479

High

1185115

KIBRA
Protein KIBRA

1

4

Small-scale

0.479

High

1185133

WNK4
Serine/threonine-protein kinase WNK4

1

6

Small-scale

0.479

High

1185141

ANM1
Protein arginine N-methyltransferase 1

1

3

High-throughput

0.479

High

1185153

WNK1
Serine/threonine-protein kinase WNK1

1

6

Small-scale

0.479

High

1185154

EGLN3
Prolyl hydroxylase EGLN3

1

4

High-throughput

0.479

High

1185158

ECT2
Protein ECT2

1

1

High-throughput

0.479

High

1185142

MYOC
Myocilin

1

0

Small-scale

0.460

High

210093

PRC1
Protein regulator of cytokinesis 1

1

0

High-throughput

0.458

High

255887

OBSL1
Obscurin-like protein 1

1

0

High-throughput

0.458

High

308826

KI20A
Kinesin-like protein KIF20A

1

0

High-throughput

0.458

High

632316

TNR6
Tumor necrosis factor receptor superfamily member 6

1

0

High-throughput

0.458

High

1185118

CGAS
Cyclic GMP-AMP synthase

1

0

Small-scale

0.458

High

1185152

CHM4B
Charged multivesicular body protein 4b

1

0

High-throughput

0.458

High

1174501

UB2R2
Ubiquitin-conjugating enzyme E2 R2

1

6

High-throughput

0.457

High

988970

FMR1
Fragile X messenger ribonucleoprotein 1

1

4

High-throughput

0.457

High

170677

AXIN1
Axin-1

1

3

Small-scale

0.445

High

1161010

SG11A
Sperm-associated antigen 11A

1

1

High-throughput

0.437

High

996164

SG11B
Sperm-associated antigen 11B

1

1

High-throughput

0.407

High

61131

KRBA1
Protein KRBA1

1

0

High-throughput

0.279

Low

622242

ALAT1
Alanine aminotransferase 1

1

0

High-throughput

0.279

Low

933009

ACTS
Actin, alpha skeletal muscle

1

0

High-throughput

0.279

Low

1166367

CF015
Uncharacterized protein C6orf15

1

0

High-throughput

0.279

Low

1185128

MITOK
Mitochondrial potassium channel

1

0

High-throughput

0.279

Low

1185137

TEFM
Transcription elongation factor, mitochondrial

1

0

High-throughput

0.279

Low

1185155

GREM2
Gremlin-2

1

0

High-throughput

0.279

Low

1185163

SUCB1
Succinate--CoA ligase [ADP-forming] subunit beta, mitochondrial

1

0

High-throughput

0.279

Low


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Last updated: 15 Jul 2024