Protein: GLI2
Zinc finger protein GLI2 (GLI family zinc finger protein 2) (Tax helper protein)

Gene: GLI2
Organism: Homo sapiens
Interactions: 69
UniProt ID: P10070

Gene Ontology (top 5):
GO:0000122 - negative regulation of transcription by RNA polymerase II
GO:0000978 - RNA polymerase II cis-regulatory region sequence-specific DNA binding
GO:0000981 - DNA-binding transcription factor activity, RNA polymerase II-specific
GO:0001501 - skeletal system development
GO:0001649 - osteoblast differentiation

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

485068

ZIC1
Zinc finger protein ZIC 1

1

18

Small-scale

0.724

High

485095

SUFU
Suppressor of fused homolog

4

11

Small-scale

0.696

High

214050

SPOP
Speckle-type POZ protein

4

5

Small-scale

0.680

High

485039

GLI3
Transcriptional activator GLI3

1

18

High-throughput

0.646

High

485070

KIF7
Kinesin-like protein KIF7

2

5

High-throughput

0.628

High

485097

FBW1A
F-box/WD repeat-containing protein 1A

2

10

Small-scale

0.619

High

313636

ZIC2
Zinc finger protein ZIC 2

1

18

Small-scale

0.618

High

485045

EGR1
Early growth response protein 1

1

19

High-throughput

0.618

High

485083

ZN521
Zinc finger protein 521

1

2

Small-scale

0.618

High

485091

STK36
Serine/threonine-protein kinase 36

1

5

Small-scale

0.618

High

485064

PTC1
Protein patched homolog 1

2

1

Small-scale

0.584

High

485040

ANDR
Androgen receptor

1

14

Small-scale

0.561

High

485082

OTUB2
Ubiquitin thioesterase OTUB2

1

0

Small-scale

0.537

High

485057

SMAD3
Mothers against decapentaplegic homolog 3

1

8

Small-scale

0.536

High

485074

CARM1
Histone-arginine methyltransferase CARM1

1

6

High-throughput

0.536

High

485088

EGLN3
Prolyl hydroxylase EGLN3

1

2

High-throughput

0.536

High

485042

SKI
Ski oncogene

1

3

Small-scale

0.527

High

485086

ASHWN
Ashwin

1

0

High-throughput

0.513

High

485043

CREB1
Cyclic AMP-responsive element-binding protein 1

1

4

Small-scale

0.501

High

485069

TAF9
Transcription initiation factor TFIID subunit 9

1

2

Small-scale

0.501

High

485085

TS101
Tumor susceptibility gene 101 protein

1

1

High-throughput

0.501

High

320799

HS74L
Heat shock 70 kDa protein 4L

1

7

High-throughput

0.500

High

485066

HERC1
Probable E3 ubiquitin-protein ligase HERC1

1

7

High-throughput

0.500

High

485078

ZSC18
Zinc finger and SCAN domain-containing protein 18

1

18

High-throughput

0.500

High

485079

HS105
Heat shock protein 105 kDa

1

9

High-throughput

0.500

High

485067

SMAD2
Mothers against decapentaplegic homolog 2

1

8

Small-scale

0.484

High

485044

PRS6A
26S proteasome regulatory subunit 6A

1

0

High-throughput

0.479

High

485047

PSA3
Proteasome subunit alpha type-3

1

0

High-throughput

0.479

High

485049

PRS7
26S proteasome regulatory subunit 7

1

0

High-throughput

0.479

High

485071

MIDN
Midnolin

1

0

High-throughput

0.479

High

485084

PSMD1
26S proteasome non-ATPase regulatory subunit 1

1

0

High-throughput

0.479

High

61293

CNOT1
CCR4-NOT transcription complex subunit 1

1

1

High-throughput

0.479

High

181777

SOCS1
Suppressor of cytokine signaling 1

1

1

Small-scale

0.479

High

257309

CNOT3
CCR4-NOT transcription complex subunit 3

1

3

High-throughput

0.479

High

272479

OFD1
Centriole and centriolar satellite protein OFD1

1

4

High-throughput

0.479

High

302474

CE152
Centrosomal protein of 152 kDa

1

2

High-throughput

0.479

High

485048

2AAA
Serine/threonine-protein phosphatase 2A 65 kDa regulatory subunit A alpha isoform

1

6

High-throughput

0.479

High

485052

2ABA
Serine/threonine-protein phosphatase 2A 55 kDa regulatory subunit B alpha isoform

1

1

High-throughput

0.479

High

485053

SUMO1
Small ubiquitin-related modifier 1

1

1

High-throughput

0.479

High

485054

UBC9
SUMO-conjugating enzyme UBC9

1

4

High-throughput

0.479

High

485055

PP2AA
Serine/threonine-protein phosphatase 2A catalytic subunit alpha isoform

1

9

High-throughput

0.479

High

485056

RNF4
E3 ubiquitin-protein ligase RNF4

1

15

High-throughput

0.479

High

485058

XIAP
E3 ubiquitin-protein ligase XIAP

1

1

Small-scale

0.479

High

485059

TLE3
Transducin-like enhancer protein 3

1

8

High-throughput

0.479

High

485062

HDAC1
Histone deacetylase 1

1

9

Small-scale

0.479

High

485063

CUL3
Cullin-3

1

20

Small-scale

0.479

High

485072

A16L1
Autophagy-related protein 16-1

1

5

High-throughput

0.479

High

485073

CEP85
Centrosomal protein of 85 kDa

1

5

High-throughput

0.479

High

485076

KDM2B
Lysine-specific demethylase 2B

1

2

High-throughput

0.479

High

485077

COP1
E3 ubiquitin-protein ligase COP1

1

3

High-throughput

0.479

High

485081

UBP7
Ubiquitin carboxyl-terminal hydrolase 7

1

10

Small-scale

0.479

High

485092

HDAC6
Histone deacetylase 6

1

11

Small-scale

0.479

High

485093

UBP21
Ubiquitin carboxyl-terminal hydrolase 21

1

1

Small-scale

0.479

High

485094

FBW1B
F-box/WD repeat-containing protein 11

1

9

Small-scale

0.479

High

485096

TNR6B
Trinucleotide repeat-containing gene 6B protein

1

2

High-throughput

0.479

High

485041

BCL2
Apoptosis regulator Bcl-2

1

0

Small-scale

0.458

High

485046

FST
Follistatin

1

0

Small-scale

0.458

High

485065

PCM1
Pericentriolar material 1 protein

1

0

High-throughput

0.458

High

485080

CNOT9
CCR4-NOT transcription complex subunit 9

1

0

High-throughput

0.458

High

485089

GRPE1
GrpE protein homolog 1, mitochondrial

1

0

High-throughput

0.458

High

485090

M1IP1
Mid1-interacting protein 1

1

0

High-throughput

0.458

High

485060

LG3BP
Galectin-3-binding protein

1

4

High-throughput

0.457

High

485051

1433Z
14-3-3 protein zeta/delta

1

2

Small-scale

0.445

High

485061

SMAD4
Mothers against decapentaplegic homolog 4

1

8

Small-scale

0.445

High

485075

ANKH1
Ankyrin repeat and KH domain-containing protein 1

1

3

High-throughput

0.437

High

485087

CPVL
Probable serine carboxypeptidase CPVL

1

0

High-throughput

0.261

Low

445714

IL6RA
Interleukin-6 receptor subunit alpha

1

0

Small-scale

0.249

Low

483378

RGPD1
RANBP2-like and GRIP domain-containing protein 1

1

0

High-throughput

0.249

Low

485050

ATPG
ATP synthase subunit gamma, mitochondrial

1

0

High-throughput

0.249

Low


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Last updated: 15 Jul 2024