Protein: MYH6
Myosin-6 (Myosin heavy chain 6) (Myosin heavy chain, cardiac muscle alpha isoform) (MyHC-alpha)

Gene: MYH6
Organism: Homo sapiens
Interactions: 59
UniProt ID: P13533

Gene Ontology (top 5):
GO:0000146 - microfilament motor activity
GO:0001701 - in utero embryonic development
GO:0001725 - stress fiber
GO:0002026 - regulation of the force of heart contraction
GO:0002027 - regulation of heart rate

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

502901

MYH3
Myosin-3

1

16

High-throughput

0.691

High

528356

MYH6
Myosin-6

1

16

Small-scale

0.647

High

528376

HIF1A
Hypoxia-inducible factor 1-alpha

2

8

High-throughput

0.628

High

528360

RPB1
DNA-directed RNA polymerase II subunit RPB1

1

0

Small-scale

0.537

High

325611

LATS1
Serine/threonine-protein kinase LATS1

1

17

High-throughput

0.536

High

528357

CFTR
Cystic fibrosis transmembrane conductance regulator

1

12

High-throughput

0.536

High

528359

KAPCB
cAMP-dependent protein kinase catalytic subunit beta

1

12

High-throughput

0.536

High

528363

MP2K3
Dual specificity mitogen-activated protein kinase kinase 3

1

20

High-throughput

0.536

High

528388

DOCK6
Dedicator of cytokinesis protein 6

1

1

High-throughput

0.536

High

528390

SORT
Sortilin

1

2

High-throughput

0.536

High

528396

AAKG2
5'-AMP-activated protein kinase subunit gamma-2

1

10

High-throughput

0.536

High

528397

HSPB8
Heat shock protein beta-8

1

9

High-throughput

0.536

High

528398

UBP24
Ubiquitin carboxyl-terminal hydrolase 24

1

6

High-throughput

0.536

High

528399

DCAF1
DDB1- and CUL4-associated factor 1

1

5

High-throughput

0.536

High

149536

COPE
Coatomer subunit epsilon

1

0

High-throughput

0.513

High

231276

GANP
Germinal-center associated nuclear protein

1

0

High-throughput

0.513

High

396875

HMGN1
Non-histone chromosomal protein HMG-14

1

0

High-throughput

0.513

High

505697

UMPS
Uridine 5'-monophosphate synthase

1

0

High-throughput

0.513

High

528367

TYB4
Thymosin beta-4

1

0

High-throughput

0.513

High

528380

FBX31
F-box only protein 31

1

0

High-throughput

0.513

High

528382

SPICE
Spindle and centriole-associated protein 1

1

0

High-throughput

0.513

High

528391

MBB1A
Myb-binding protein 1A

1

0

High-throughput

0.513

High

528375

HSPB2
Heat shock protein beta-2

1

9

High-throughput

0.508

High

368902

ESR1
Estrogen receptor

1

12

Small-scale

0.501

High

528370

CACO2
Calcium-binding and coiled-coil domain-containing protein 2

1

17

Small-scale

0.501

High

528385

TRI63
E3 ubiquitin-protein ligase TRIM63

1

7

Small-scale

0.501

High

528392

NEUL2
Neuralized-like protein 2

1

1

Small-scale

0.501

High

528395

CACO1
Calcium-binding and coiled-coil domain-containing protein 1

1

18

Small-scale

0.501

High

61749

BDP1
Transcription factor TFIIIB component B'' homolog

1

13

High-throughput

0.489

High

319112

BRD1
Bromodomain-containing protein 1

1

1

High-throughput

0.489

High

528374

TRIPB
Thyroid receptor-interacting protein 11

1

16

High-throughput

0.489

High

528381

SPT2
Protein SPT2 homolog

1

1

High-throughput

0.489

High

528383

LZTR1
Leucine-zipper-like transcriptional regulator 1

1

9

High-throughput

0.489

High

528384

ABTB2
Ankyrin repeat and BTB/POZ domain-containing protein 2

1

9

High-throughput

0.489

High

362053

MBP
Myelin basic protein

1

1

High-throughput

0.479

High

528358

CXA1
Gap junction alpha-1 protein

1

2

Small-scale

0.479

High

528361

MSX2
Homeobox protein MSX-2

1

1

High-throughput

0.479

High

528362

NSF
Vesicle-fusing ATPase

1

1

High-throughput

0.479

High

528364

MCM2
DNA replication licensing factor MCM2

1

7

High-throughput

0.479

High

528368

CDK3
Cyclin-dependent kinase 3

1

12

High-throughput

0.479

High

528369

STK4
Serine/threonine-protein kinase 4

1

20

High-throughput

0.479

High

528371

STK3
Serine/threonine-protein kinase 3

1

16

High-throughput

0.479

High

528372

DYR1A
Dual specificity tyrosine-phosphorylation-regulated kinase 1A

1

14

High-throughput

0.479

High

528373

ELOC
Elongin-C

1

1

High-throughput

0.479

High

528386

OPTN
Optineurin

1

19

Small-scale

0.479

High

528393

TRIM6
Tripartite motif-containing protein 6

1

3

Small-scale

0.479

High

528394

SMYD2
N-lysine methyltransferase SMYD2

1

2

High-throughput

0.479

High

324202

BAG3
BAG family molecular chaperone regulator 3

1

0

Small-scale

0.458

High

111063

I3L0N3
Vesicle-fusing ATPase

1

1

High-throughput

0.445

High

528366

PP1A
Serine/threonine-protein phosphatase PP1-alpha catalytic subunit

1

9

High-throughput

0.445

High

528365

FOXA1
Hepatocyte nuclear factor 3-alpha

1

1

High-throughput

0.437

High

528387

LRC39
Leucine-rich repeat-containing protein 39

1

4

Small-scale

0.417

High

91329

E5RHG8
Elongin-C

1

1

High-throughput

0.407

High

111418

J3QQK6
Myelin basic protein

1

1

High-throughput

0.407

High

528377

T132A
Transmembrane protein 132A

1

0

High-throughput

0.279

Low

528378

EDRF1
Erythroid differentiation-related factor 1

1

0

High-throughput

0.279

Low

528379

IPIL2
Inositol 1,4,5-trisphosphate receptor-interacting protein-like 2

1

0

High-throughput

0.279

Low

528389

PIGS
GPI transamidase component PIG-S

1

0

High-throughput

0.279

Low


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Last updated: 15 Jul 2024