Protein: ZFHX3
Zinc finger homeobox protein 3 (AT motif-binding factor 1) (AT-binding transcription factor 1) (Alpha-fetoprotein enhancer-binding protein) (Zinc finger homeodomain protein 3) (ZFH-3)

Gene: ZFHX3
Organism: Homo sapiens
Interactions: 96
UniProt ID: Q15911

Gene Ontology (top 5):
GO:0000122 - negative regulation of transcription by RNA polymerase II
GO:0000785 - chromatin
GO:0000976 - transcription cis-regulatory region binding
GO:0000978 - RNA polymerase II cis-regulatory region sequence-specific DNA binding
GO:0000981 - DNA-binding transcription factor activity, RNA polymerase II-specific

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

540851

PO2F1
POU domain, class 2, transcription factor 1

2

11

High-throughput

0.783

High

724241

MSX2
Homeobox protein MSX-2

2

12

High-throughput

0.783

High

944032

PO6F2
POU domain, class 6, transcription factor 2

2

12

High-throughput

0.783

High

1080545

ZN620
Zinc finger protein 620

2

5

High-throughput

0.783

High

1080548

ZFHX4
Zinc finger homeobox protein 4

1

4

High-throughput

0.691

High

160589

AURKA
Aurora kinase A

1

1

Small-scale

0.647

High

1059640

CHD4
Chromodomain-helicase-DNA-binding protein 4

3

5

Small-scale

0.640

High

550392

ZEP1
Zinc finger protein 40

1

7

High-throughput

0.621

High

62595

DPRX
Divergent paired-related homeobox

1

13

High-throughput

0.618

High

197714

CRX
Cone-rod homeobox protein

1

15

High-throughput

0.618

High

211860

TLX3
T-cell leukemia homeobox protein 3

1

13

High-throughput

0.618

High

213339

TLX2
T-cell leukemia homeobox protein 2

1

12

High-throughput

0.618

High

505222

EGR2
E3 SUMO-protein ligase EGR2

1

11

High-throughput

0.618

High

620157

PAX7
Paired box protein Pax-7

1

13

High-throughput

0.618

High

641420

PAX6
Paired box protein Pax-6

1

10

High-throughput

0.618

High

679110

TLX1
T-cell leukemia homeobox protein 1

1

12

High-throughput

0.618

High

799109

NKX21
Homeobox protein Nkx-2.1

1

17

High-throughput

0.618

High

839748

LHX2
LIM/homeobox protein Lhx2

1

11

High-throughput

0.618

High

882128

GSC
Homeobox protein goosecoid

1

11

High-throughput

0.618

High

884162

KLF3
Krueppel-like factor 3

1

20

High-throughput

0.618

High

1080535

TBR1
T-box brain protein 1

1

4

High-throughput

0.618

High

1080569

VSX1
Visual system homeobox 1

1

17

High-throughput

0.618

High

146503

BHE40
Class E basic helix-loop-helix protein 40

2

2

High-throughput

0.606

High

264051

TACC1
Transforming acidic coiled-coil-containing protein 1

2

3

High-throughput

0.606

High

536845

TRI27
Zinc finger protein RFP

2

5

High-throughput

0.606

High

985705

DEUP1
Deuterosome assembly protein 1

2

1

High-throughput

0.606

High

993437

TLE5
TLE family member 5

2

5

High-throughput

0.606

High

1080537

MTUS2
Microtubule-associated tumor suppressor candidate 2

2

2

High-throughput

0.606

High

1080549

USBP1
Harmonin-binding protein USHBP1

2

1

High-throughput

0.606

High

1080550

TRIMM
Probable E3 ubiquitin-protein ligase TRIML2

2

6

High-throughput

0.606

High

1080563

TRI54
Tripartite motif-containing protein 54

2

5

High-throughput

0.606

High

1080566

PICK1
PRKCA-binding protein

2

1

High-throughput

0.606

High

1080568

CNOT2
CCR4-NOT transcription complex subunit 2

2

1

High-throughput

0.606

High

882914

RBM11
Splicing regulator RBM11

2

0

High-throughput

0.580

High

1080542

CYTSA
Cytospin-A

2

0

High-throughput

0.580

High

1080546

CSN6
COP9 signalosome complex subunit 6

2

0

High-throughput

0.580

High

1080565

CSTP1
Centriolar satellite-associated tubulin polyglutamylase complex regulator 1

2

0

High-throughput

0.580

High

1043824

DYR1A
Dual specificity tyrosine-phosphorylation-regulated kinase 1A

1

1

High-throughput

0.575

High

369689

ESR1
Estrogen receptor

2

20

High-throughput

0.571

High

62309

GG6L9
Golgin subfamily A member 6-like protein 9

2

6

High-throughput

0.553

High

280587

KRT34
Keratin, type I cuticular Ha4

2

6

High-throughput

0.553

High

975662

LMNB2
Lamin-B2

2

5

High-throughput

0.553

High

994896

GOGA2
Golgin subfamily A member 2

2

4

High-throughput

0.553

High

1071180

K1H1
Keratin, type I cuticular Ha1

2

6

High-throughput

0.553

High

1080552

CEP70
Centrosomal protein of 70 kDa

2

2

High-throughput

0.553

High

1080574

PIAS3
E3 SUMO-protein ligase PIAS3

1

0

Small-scale

0.549

High

1080544

TRAF7
E3 ubiquitin-protein ligase TRAF7

1

3

High-throughput

0.536

High

1080553

TGFA1
Transforming growth factor-beta receptor-associated protein 1

1

1

High-throughput

0.536

High

1080562

TCAB1
Telomerase Cajal body protein 1

1

3

High-throughput

0.536

High

1080570

TRPS1
Zinc finger transcription factor Trps1

1

8

High-throughput

0.536

High

1080543

K1C40
Keratin, type I cytoskeletal 40

1

6

High-throughput

0.523

High

150295

CCS
Copper chaperone for superoxide dismutase

1

0

High-throughput

0.513

High

210905

GET3
ATPase GET3

1

0

High-throughput

0.513

High

1080539

BEND3
BEN domain-containing protein 3

1

0

High-throughput

0.513

High

1080567

ALKB4
Alpha-ketoglutarate-dependent dioxygenase alkB homolog 4

1

0

Small-scale

0.486

High

1080555

PIBF1
Progesterone-induced-blocking factor 1

1

1

High-throughput

0.481

High

263648

PR40A
Pre-mRNA-processing factor 40 homolog A

1

0

Small-scale

0.480

High

487476

ANDR
Androgen receptor

1

19

High-throughput

0.479

High

620354

GATA2
Endothelial transcription factor GATA-2

1

6

High-throughput

0.479

High

658511

TEAD1
Transcriptional enhancer factor TEF-1

1

2

High-throughput

0.479

High

727524

HNF1B
Hepatocyte nuclear factor 1-beta

1

13

High-throughput

0.479

High

727749

SOX5
Transcription factor SOX-5

1

18

High-throughput

0.479

High

727873

SOX6
Transcription factor SOX-6

1

16

High-throughput

0.479

High

818089

SOX2
Transcription factor SOX-2

1

17

High-throughput

0.479

High

878413

PAX9
Paired box protein Pax-9

1

10

High-throughput

0.479

High

882320

BCAR1
Breast cancer anti-estrogen resistance protein 1

1

4

High-throughput

0.479

High

934805

H31
Histone H3.1

1

6

High-throughput

0.479

High

980760

TLE3
Transducin-like enhancer protein 3

1

8

High-throughput

0.479

High

1018506

CHD3
Chromodomain-helicase-DNA-binding protein 3

1

7

High-throughput

0.479

High

1021292

FOXL1
Forkhead box protein L1

1

4

High-throughput

0.479

High

1038413

HDAC1
Histone deacetylase 1

1

10

High-throughput

0.479

High

1052670

TRI25
E3 ubiquitin/ISG15 ligase TRIM25

1

7

Small-scale

0.479

High

1060293

NFIX
Nuclear factor 1 X-type

1

7

High-throughput

0.479

High

1080551

NUP43
Nucleoporin Nup43

1

9

High-throughput

0.479

High

1080554

PHIP
PH-interacting protein

1

7

High-throughput

0.479

High

1080556

ESR2
Estrogen receptor beta

1

20

High-throughput

0.479

High

1080557

PF21A
PHD finger protein 21A

1

13

High-throughput

0.479

High

1080558

SNR40
U5 small nuclear ribonucleoprotein 40 kDa protein

1

2

High-throughput

0.479

High

1080560

CIC
Protein capicua homolog

1

16

High-throughput

0.479

High

1080561

FEV
Protein FEV

1

7

High-throughput

0.479

High

1080571

RCOR1
REST corepressor 1

1

5

High-throughput

0.479

High

1080536

Q4G0R1
PIBF1 protein

1

1

High-throughput

0.470

High

167691

LSM1
U6 snRNA-associated Sm-like protein LSm1

1

0

High-throughput

0.458

High

523786

XRCC6
X-ray repair cross-complementing protein 6

1

0

High-throughput

0.458

High

776700

STAT3
Signal transducer and activator of transcription 3

1

0

Small-scale

0.458

High

1080540

DCA12
DDB1- and CUL4-associated factor 12

1

0

High-throughput

0.458

High

1080547

PARPT
Protein mono-ADP-ribosyltransferase TIPARP

1

0

High-throughput

0.458

High

346887

MYC
Myc proto-oncogene protein

1

3

High-throughput

0.445

High

1080572

NINL
Ninein-like protein

1

2

High-throughput

0.439

High

1080538

EFHC2
EF-hand domain-containing family member C2

2

0

High-throughput

0.316

High

1080541

TTC23
Tetratricopeptide repeat protein 23

2

0

High-throughput

0.316

High

1080559

SYGP1
Ras/Rap GTPase-activating protein SynGAP

2

0

High-throughput

0.288

High

1080564

GCP60
Golgi resident protein GCP60

1

0

High-throughput

0.279

Low

1080573

PCDG9
Protocadherin gamma-A9

1

0

High-throughput

0.279

Low

329748

AGR2
Anterior gradient protein 2 homolog

1

0

High-throughput

0.249

Low

912925

ARF6
ADP-ribosylation factor 6

1

0

High-throughput

0.249

Low


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Last updated: 15 Jul 2024