Protein: EAF1
ELL-associated factor 1

Gene: EAF1
Organism: Homo sapiens
Interactions: 121
UniProt ID: Q96JC9

Gene Ontology (top 5):
GO:0003711 - transcription elongation factor activity
GO:0005654 - nucleoplasm
GO:0006368 - transcription elongation by RNA polymerase II
GO:0008023 - transcription elongation factor complex
GO:0015030 - Cajal body

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

876661

ELL
RNA polymerase II elongation factor ELL

7

5

Small-scale

0.968

High

130169

ELL2
RNA polymerase II elongation factor ELL2

7

5

Small-scale

0.965

High

1295112

ELL3
RNA polymerase II elongation factor ELL3

6

5

High-throughput

0.950

High

899001

PSME3
Proteasome activator complex subunit 3

5

1

High-throughput

0.726

High

788058

AF9
Protein AF-9

5

1

Small-scale

0.718

High

850824

AFF1
AF4/FMR2 family member 1

4

2

High-throughput

0.699

High

1295120

AFF4
AF4/FMR2 family member 4

4

2

High-throughput

0.699

High

1145661

ICE2
Little elongation complex subunit 2

4

0

High-throughput

0.670

High

1295125

ICE1
Little elongation complex subunit 1

4

0

High-throughput

0.670

High

817729

PI42A
Phosphatidylinositol 5-phosphate 4-kinase type-2 alpha

3

3

High-throughput

0.667

High

942437

PI42B
Phosphatidylinositol 5-phosphate 4-kinase type-2 beta

3

3

High-throughput

0.667

High

974509

ENL
Protein ENL

3

1

High-throughput

0.667

High

1253113

PI42C
Phosphatidylinositol 5-phosphate 4-kinase type-2 gamma

3

3

High-throughput

0.667

High

1295104

KLDC3
Kelch domain-containing protein 3

3

1

High-throughput

0.667

High

1295113

E41L5
Band 4.1-like protein 5

3

1

High-throughput

0.667

High

1295126

LC7L2
Putative RNA-binding protein Luc7-like 2

3

2

High-throughput

0.667

High

1295102

STAC3
SH3 and cysteine-rich domain-containing protein 3

3

2

High-throughput

0.654

High

317853

CPSF4
Cleavage and polyadenylation specificity factor subunit 4

3

0

High-throughput

0.638

High

508659

TOP1
DNA topoisomerase 1

3

0

High-throughput

0.638

High

1075302

TAF1C
TATA box-binding protein-associated factor RNA polymerase I subunit C

3

0

High-throughput

0.638

High

1075331

TAF1A
TATA box-binding protein-associated factor RNA polymerase I subunit A

3

0

High-throughput

0.638

High

1121971

TAF1B
TATA box-binding protein-associated factor RNA polymerase I subunit B

3

0

High-throughput

0.638

High

1232271

PLCD3
1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase delta-3

3

0

High-throughput

0.638

High

1286795

EAF2
ELL-associated factor 2

3

0

High-throughput

0.638

High

1295110

TAF1D
TATA box-binding protein-associated factor RNA polymerase I subunit D

3

0

High-throughput

0.638

High

1295119

IKBL1
NF-kappa-B inhibitor-like protein 1

3

0

High-throughput

0.638

High

1295128

CABIN
Calcineurin-binding protein cabin-1

3

0

High-throughput

0.638

High

253598

CAPON
Carboxyl-terminal PDZ ligand of neuronal nitric oxide synthase protein

3

1

High-throughput

0.609

High

1139167

RSBN1
Lysine-specific demethylase 9

3

1

High-throughput

0.609

High

1160775

RSBNL
Lysine-specific demethylase RSBN1L

3

1

High-throughput

0.609

High

1295109

E41LB
Band 4.1-like protein 4B

3

1

High-throughput

0.609

High

1295114

LUC7L
Putative RNA-binding protein Luc7-like 1

3

2

High-throughput

0.609

High

1075157

TCEA2
Transcription elongation factor A protein 2

2

4

High-throughput

0.606

High

1117685

ARI4B
AT-rich interactive domain-containing protein 4B

2

1

High-throughput

0.606

High

1222211

YAF2
YY1-associated factor 2

2

1

High-throughput

0.606

High

1233147

RYBP
RING1 and YY1-binding protein

2

1

High-throughput

0.606

High

1255885

GRHL3
Grainyhead-like protein 3 homolog

2

1

High-throughput

0.606

High

1270282

TF2H4
General transcription factor IIH subunit 4

2

1

High-throughput

0.606

High

1139900

USPL1
SUMO-specific isopeptidase USPL1

2

0

High-throughput

0.602

High

841851

CDK9
Cyclin-dependent kinase 9

2

0

Small-scale

0.592

High

722631

T2FA
General transcription factor IIF subunit 1

2

0

High-throughput

0.585

High

1285570

PINX1
PIN2/TERF1-interacting telomerase inhibitor 1

2

0

High-throughput

0.585

High

1295127

RBMX2
RNA-binding motif protein, X-linked 2

2

0

High-throughput

0.585

High

1230512

CCAR2
Cell cycle and apoptosis regulator protein 2

2

1

Small-scale

0.584

High

1237260

BEND7
BEN domain-containing protein 7

2

1

High-throughput

0.584

High

253156

HSF2B
Heat shock factor 2-binding protein

2

0

High-throughput

0.580

High

304699

ZN202
Zinc finger protein 202

2

0

High-throughput

0.580

High

312765

TFIP8
Tumor necrosis factor alpha-induced protein 8

2

0

High-throughput

0.580

High

641523

PAX6
Paired box protein Pax-6

2

0

High-throughput

0.580

High

697764

TF2H1
General transcription factor IIH subunit 1

2

0

High-throughput

0.580

High

856032

ZN143
Zinc finger protein 143

2

0

High-throughput

0.580

High

1020867

TRAF2
TNF receptor-associated factor 2

2

0

High-throughput

0.580

High

1049305

KEAP1
Kelch-like ECH-associated protein 1

2

0

High-throughput

0.580

High

1183752

DPPA4
Developmental pluripotency-associated protein 4

2

0

High-throughput

0.580

High

1251132

G45IP
Large ribosomal subunit protein mL64

2

0

High-throughput

0.580

High

1295108

TDIF1
Deoxynucleotidyltransferase terminal-interacting protein 1

2

0

High-throughput

0.580

High

993553

TLE5
TLE family member 5

2

1

High-throughput

0.576

High

1238742

TAC2N
Tandem C2 domains nuclear protein

2

1

High-throughput

0.574

High

132991

SDCB1
Syntenin-1

1

2

High-throughput

0.573

High

1016839

TFCP2
Alpha-globin transcription factor CP2

1

1

High-throughput

0.573

High

1029746

TIF1B
Transcription intermediary factor 1-beta

1

1

Small-scale

0.561

High

62394

GG6L9
Golgin subfamily A member 6-like protein 9

2

1

High-throughput

0.553

High

1131049

VAX1
Ventral anterior homeobox 1

2

1

High-throughput

0.553

High

215917

ZBT14
Zinc finger and BTB domain-containing protein 14

1

0

High-throughput

0.549

High

313457

MED26
Mediator of RNA polymerase II transcription subunit 26

1

1

High-throughput

0.536

High

471642

TFPT
TCF3 fusion partner

1

1

Small-scale

0.515

High

163151

XPO1
Exportin-1

1

2

High-throughput

0.479

High

308243

LC7L3
Luc7-like protein 3

1

2

High-throughput

0.479

High

1044051

DYR1A
Dual specificity tyrosine-phosphorylation-regulated kinase 1A

1

1

High-throughput

0.479

High

1295111

SP110
Sp110 nuclear body protein

1

1

High-throughput

0.479

High

177357

HDAC3
Histone deacetylase 3

1

0

Small-scale

0.458

High

199806

SNUT1
U4/U6.U5 tri-snRNP-associated protein 1

1

0

High-throughput

0.458

High

627331

MCM3
DNA replication licensing factor MCM3

1

0

High-throughput

0.458

High

658413

DPOD1
DNA polymerase delta catalytic subunit

1

0

High-throughput

0.458

High

802478

ATRX
Transcriptional regulator ATRX

1

0

High-throughput

0.458

High

875715

MFAP1
Microfibrillar-associated protein 1

1

0

High-throughput

0.458

High

1061043

NOLC1
Nucleolar and coiled-body phosphoprotein 1

1

0

High-throughput

0.458

High

1164867

FIP1
Pre-mRNA 3'-end-processing factor FIP1

1

0

High-throughput

0.458

High

1293717

NAF1
H/ACA ribonucleoprotein complex non-core subunit NAF1

1

0

High-throughput

0.458

High

1295103

RBM14
RNA-binding protein 14

1

0

High-throughput

0.458

High

1295121

DDX20
Probable ATP-dependent RNA helicase DDX20

1

0

High-throughput

0.458

High

1295123

RUVB2
RuvB-like 2

1

1

High-throughput

0.445

High

1295124

RUVB1
RuvB-like 1

1

1

High-throughput

0.445

High

833643

NUMB
Protein numb homolog

1

1

High-throughput

0.439

High

1295117

MRGBP
MRG/MORF4L-binding protein

1

0

High-throughput

0.426

High

1295116

HOME3
Homer protein homolog 3

4

0

High-throughput

0.367

High

1286225

FGGY
FGGY carbohydrate kinase domain-containing protein

3

0

High-throughput

0.342

High

1241307

CAMKV
CaM kinase-like vesicle-associated protein

2

0

High-throughput

0.328

High

1018424

SFSWA
Splicing factor, suppressor of white-apricot homolog

2

0

High-throughput

0.318

High

1132785

CI114
Putative methyltransferase C9orf114

2

0

High-throughput

0.318

High

1295122

RL26L
Ribosomal protein uL24-like

2

0

High-throughput

0.318

High

330118

DRC4
Dynein regulatory complex subunit 4

2

0

High-throughput

0.316

High

381024

SEMG1
Semenogelin-1

2

0

High-throughput

0.316

High

581204

TNNI1
Troponin I, slow skeletal muscle

2

0

High-throughput

0.316

High

739803

SRP14
Signal recognition particle 14 kDa protein

2

0

High-throughput

0.316

High

1126979

GSAML
Germinal center-associated signaling and motility-like protein

2

0

High-throughput

0.316

High

1161652

GASP3
G protein-coupled receptor associated sorting protein 3

2

0

High-throughput

0.316

High

1169347

ZN620
Zinc finger protein 620

2

0

High-throughput

0.316

High

1198310

K1328
Protein hinderin

2

0

High-throughput

0.316

High

1202926

F228A
Protein FAM228A

2

0

High-throughput

0.316

High

1237939

MB213
Protein mab-21-like 3

2

0

High-throughput

0.316

High

1241977

CC150
Coiled-coil domain-containing protein 150

2

0

High-throughput

0.316

High

1245739

CEP70
Centrosomal protein of 70 kDa

2

0

High-throughput

0.316

High

1287464

AP2M1
AP-2 complex subunit mu

2

0

High-throughput

0.316

High

1295107

TRI62
E3 ubiquitin-protein ligase TRIM62

2

0

High-throughput

0.316

High

1295115

PICK1
PRKCA-binding protein

2

0

High-throughput

0.316

High

1295118

PIHD1
PIH1 domain-containing protein 1

2

0

High-throughput

0.316

High

1251520

CEP76
Centrosomal protein of 76 kDa

1

0

High-throughput

0.299

High

1254158

MIPO1
Mirror-image polydactyly gene 1 protein

1

0

High-throughput

0.299

High

897936

RAP1B
Ras-related protein Rap-1b

1

0

High-throughput

0.279

Low

1232808

FGRL1
Fibroblast growth factor receptor-like 1

1

0

High-throughput

0.279

Low

1235105

CCD33
Coiled-coil domain-containing protein 33

1

0

High-throughput

0.265

Low

395490

A4
Amyloid-beta precursor protein

1

0

High-throughput

0.261

Low

1191854

SH3R1
E3 ubiquitin-protein ligase SH3RF1

1

0

High-throughput

0.251

Low

63092

CC154
Coiled-coil domain-containing protein 154

1

0

High-throughput

0.249

Low

120018

AP3B1
AP-3 complex subunit beta-1

1

0

High-throughput

0.249

Low

809392

IQGA1
Ras GTPase-activating-like protein IQGAP1

1

0

High-throughput

0.249

Low

1074522

SP17
Sperm surface protein Sp17

1

0

High-throughput

0.249

Low

1224772

ASPM
Abnormal spindle-like microcephaly-associated protein

1

0

High-throughput

0.249

Low

1295105

E2AK1
Eukaryotic translation initiation factor 2-alpha kinase 1

1

0

High-throughput

0.249

Low

1295106

MMTA2
Multiple myeloma tumor-associated protein 2

1

0

High-throughput

0.249

Low


Service provided by Combinatics, Japan

Last updated: 15 Jul 2024