Protein: L2GL2
LLGL scribble cell polarity complex component 2 (HGL) (Lethal(2) giant larvae protein homolog 2)

Gene: L2GL2, LLGL2
Organism: Homo sapiens
Interactions: 123
UniProt ID: Q6P1M3

Gene Ontology (top 5):
GO:0005096 - GTPase activator activity
GO:0005737 - cytoplasm
GO:0005829 - cytosol
GO:0005886 - plasma membrane
GO:0005912 - adherens junction

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

829020

UBE2A
Ubiquitin-conjugating enzyme E2 A

2

1

High-throughput

0.811

High

1158575

UBE2O
(E3-independent) E2 ubiquitin-conjugating enzyme

2

4

High-throughput

0.811

High

1071538

L2GL1
Lethal(2) giant larvae protein homolog 1

2

3

High-throughput

0.776

High

1158539

L2GL2
LLGL scribble cell polarity complex component 2

2

10

High-throughput

0.776

High

784030

KPCI
Protein kinase C iota type

10

9

Small-scale

0.756

High

1158573

PAR6B
Partitioning defective 6 homolog beta

8

8

Small-scale

0.755

High

983860

KPCZ
Protein kinase C zeta type

8

10

High-throughput

0.750

High

1158540

BRWD3
Bromodomain and WD repeat-containing protein 3

2

17

High-throughput

0.726

High

1158580

PAR6A
Partitioning defective 6 homolog alpha

4

8

High-throughput

0.702

High

1158572

PAR6G
Partitioning defective 6 homolog gamma

4

8

High-throughput

0.699

High

787504

MTOR
Serine/threonine-protein kinase mTOR

1

5

High-throughput

0.691

High

1082234

DDB1
DNA damage-binding protein 1

1

8

High-throughput

0.691

High

1158567

LYST
Lysosomal-trafficking regulator

1

7

High-throughput

0.691

High

1158581

BIRC6
Baculoviral IAP repeat-containing protein 6

1

6

High-throughput

0.691

High

1158596

PKHG1
Pleckstrin homology domain-containing family G member 1

1

1

High-throughput

0.691

High

1158603

DCAF1
DDB1- and CUL4-associated factor 1

3

16

High-throughput

0.675

High

1158554

KBTB7
Kelch repeat and BTB domain-containing protein 7

3

3

High-throughput

0.667

High

1158583

RAD18
E3 ubiquitin-protein ligase RAD18

3

1

High-throughput

0.667

High

526663

GILT
Gamma-interferon-inducible lysosomal thiol reductase

3

0

High-throughput

0.638

High

673807

NKTR
NK-tumor recognition protein

2

2

High-throughput

0.628

High

934248

CSK21
Casein kinase II subunit alpha

2

7

High-throughput

0.628

High

1025304

LIPA1
Liprin-alpha-1

2

3

High-throughput

0.628

High

1078268

RAB30
Ras-related protein Rab-30

2

4

High-throughput

0.628

High

1158544

KBTB6
Kelch repeat and BTB domain-containing protein 6

2

3

High-throughput

0.628

High

1158548

ZN687
Zinc finger protein 687

2

1

High-throughput

0.628

High

1158589

RCOR3
REST corepressor 3

2

3

High-throughput

0.628

High

1158597

ZMYD8
MYND-type zinc finger-containing chromatin reader ZMYND8

2

6

High-throughput

0.628

High

1083662

TAF9
Transcription initiation factor TFIID subunit 9

1

1

High-throughput

0.618

High

243461

DNJA2
DnaJ homolog subfamily A member 2

2

12

High-throughput

0.611

High

990125

C1QBP
Complement component 1 Q subcomponent-binding protein, mitochondrial

2

0

High-throughput

0.602

High

1019319

TRI26
Tripartite motif-containing protein 26

2

0

High-throughput

0.602

High

1158553

CATIN
Splicing factor Cactin

2

0

High-throughput

0.602

High

350262

RASK
GTPase KRas

2

10

High-throughput

0.584

High

1158545

ZC3H3
Zinc finger CCCH domain-containing protein 3

1

0

High-throughput

0.578

High

1158556

ZN592
Zinc finger protein 592

2

1

High-throughput

0.574

High

1158571

DDA1
DET1- and DDB1-associated protein 1

2

1

High-throughput

0.574

High

1158579

HM20A
High mobility group protein 20A

2

7

High-throughput

0.574

High

1158594

RCOR1
REST corepressor 1

2

3

High-throughput

0.574

High

498294

KAP0
cAMP-dependent protein kinase type I-alpha regulatory subunit

2

1

High-throughput

0.571

High

925363

RAC1
Ras-related C3 botulinum toxin substrate 1

2

16

High-throughput

0.571

High

128582

DNM1L
Dynamin-1-like protein

1

2

High-throughput

0.536

High

172870

CASC3
Protein CASC3

1

3

High-throughput

0.536

High

224969

ZNRD2
Protein ZNRD2

1

1

High-throughput

0.536

High

313844

SVIL
Supervillin

1

2

High-throughput

0.536

High

547820

ATF2
Cyclic AMP-dependent transcription factor ATF-2

1

3

High-throughput

0.536

High

803590

BAG6
Large proline-rich protein BAG6

1

6

High-throughput

0.536

High

944176

DEN2B
DENN domain-containing protein 2B

1

3

High-throughput

0.536

High

1017314

BPTF
Nucleosome-remodeling factor subunit BPTF

1

14

High-throughput

0.536

High

1028385

M3K1
Mitogen-activated protein kinase kinase kinase 1

1

2

High-throughput

0.536

High

1050477

DOCK1
Dedicator of cytokinesis protein 1

1

3

High-throughput

0.536

High

1061001

NOLC1
Nucleolar and coiled-body phosphoprotein 1

1

1

High-throughput

0.536

High

1069381

TEBP
Prostaglandin E synthase 3

1

3

High-throughput

0.536

High

1147952

FMN1
Formin-1

1

2

High-throughput

0.536

High

1158541

FIP1
Pre-mRNA 3'-end-processing factor FIP1

1

1

High-throughput

0.536

High

1158546

PHAR4
Phosphatase and actin regulator 4

1

3

High-throughput

0.536

High

1158551

NEK7
Serine/threonine-protein kinase Nek7

1

2

High-throughput

0.536

High

1158555

PALLD
Palladin

1

2

High-throughput

0.536

High

1158558

EFMT3
EEF1A lysine methyltransferase 3

1

1

High-throughput

0.536

High

1158561

ELMO3
Engulfment and cell motility protein 3

1

1

High-throughput

0.536

High

1158563

GCC1
GRIP and coiled-coil domain-containing protein 1

1

11

High-throughput

0.536

High

1158564

ELMO2
Engulfment and cell motility protein 2

1

1

High-throughput

0.536

High

1158570

MKNK1
MAP kinase-interacting serine/threonine-protein kinase 1

1

1

High-throughput

0.536

High

1158574

GTPB4
GTP-binding protein 4

1

3

High-throughput

0.536

High

1158578

E41LB
Band 4.1-like protein 4B

1

4

High-throughput

0.536

High

1158587

BCLF1
Bcl-2-associated transcription factor 1

1

5

High-throughput

0.536

High

1158593

DAPK2
Death-associated protein kinase 2

1

1

High-throughput

0.536

High

1158599

EXO1
Exonuclease 1

1

1

High-throughput

0.536

High

230633

KATIP
Katanin-interacting protein

1

0

High-throughput

0.513

High

538562

CCNB1
G2/mitotic-specific cyclin-B1

1

0

High-throughput

0.513

High

1076227

ZNHI3
Zinc finger HIT domain-containing protein 3

1

0

High-throughput

0.513

High

1128057

CEP78
Centrosomal protein of 78 kDa

1

0

High-throughput

0.513

High

1158547

ABCA7
Phospholipid-transporting ATPase ABCA7

1

0

High-throughput

0.513

High

1158549

NKAP
NF-kappa-B-activating protein

1

0

High-throughput

0.513

High

1158550

C99L2
CD99 antigen-like protein 2

1

0

High-throughput

0.513

High

1158568

ATP5S
ATP synthase subunit s, mitochondrial

1

0

High-throughput

0.513

High

1158569

ECSIT
Evolutionarily conserved signaling intermediate in Toll pathway, mitochondrial

1

0

High-throughput

0.513

High

1158590

IMPCT
Protein IMPACT

1

0

High-throughput

0.513

High

232253

KDM1A
Lysine-specific histone demethylase 1A

1

1

High-throughput

0.489

High

873434

P5CS
Delta-1-pyrroline-5-carboxylate synthase

1

5

High-throughput

0.489

High

1135191

RBM26
RNA-binding protein 26

1

2

High-throughput

0.489

High

1138174

BRE1A
E3 ubiquitin-protein ligase BRE1A

1

8

High-throughput

0.489

High

1147501

UTP25
U3 small nucleolar RNA-associated protein 25 homolog

1

1

High-throughput

0.489

High

1158560

PF21A
PHD finger protein 21A

1

4

High-throughput

0.489

High

1158562

ZN707
Zinc finger protein 707

1

1

High-throughput

0.489

High

1158566

IWS1
Protein IWS1 homolog

1

1

High-throughput

0.489

High

1158577

BHE41
Class E basic helix-loop-helix protein 41

1

2

High-throughput

0.489

High

1158585

IMP3
U3 small nucleolar ribonucleoprotein protein IMP3

1

5

High-throughput

0.489

High

1158588

HM20B
SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily E member 1-related

1

5

High-throughput

0.489

High

1158592

HMGX4
HMG domain-containing protein 4

1

7

High-throughput

0.489

High

1158601

TR150
Thyroid hormone receptor-associated protein 3

1

7

High-throughput

0.489

High

227793

PRKN
E3 ubiquitin-protein ligase parkin

1

6

High-throughput

0.479

High

349406

RASH
GTPase HRas

1

7

High-throughput

0.479

High

636358

DNJB1
DnaJ homolog subfamily B member 1

1

12

High-throughput

0.479

High

681490

DNJA1
DnaJ homolog subfamily A member 1

1

12

High-throughput

0.479

High

912963

ARF6
ADP-ribosylation factor 6

1

4

High-throughput

0.479

High

1036666

SQSTM
Sequestosome-1

1

2

High-throughput

0.479

High

1063873

TNIP1
TNFAIP3-interacting protein 1

1

7

High-throughput

0.479

High

1158543

RBBP6
E3 ubiquitin-protein ligase RBBP6

1

4

High-throughput

0.479

High

1158552

PAR3L
Partitioning defective 3 homolog B

1

3

Small-scale

0.479

High

1158557

ESR2
Estrogen receptor beta

1

9

High-throughput

0.479

High

1158584

RN146
E3 ubiquitin-protein ligase RNF146

1

1

Small-scale

0.479

High

1158591

ZRAN1
Ubiquitin thioesterase ZRANB1

1

2

High-throughput

0.479

High

1158595

BAG5
BAG family molecular chaperone regulator 5

1

1

High-throughput

0.479

High

1158598

CHIP
E3 ubiquitin-protein ligase CHIP

1

8

High-throughput

0.479

High

1158600

NUDC
Nuclear migration protein nudC

1

6

High-throughput

0.479

High

1158602

SGT1
Protein SGT1 homolog

1

6

High-throughput

0.479

High

352140

INS
Insulin [Cleaved into: Insulin B chain; Insulin A chain]

1

0

High-throughput

0.458

High

1035476

SMAD4
Mothers against decapentaplegic homolog 4

1

0

High-throughput

0.458

High

1123412

H90B4
Putative heat shock protein HSP 90-beta 4

1

6

High-throughput

0.445

High

1158586

SPHK1
Sphingosine kinase 1

1

1

Small-scale

0.445

High

1075674

SF01
Splicing factor 1

1

1

High-throughput

0.437

High

1158604

TIM13
Mitochondrial import inner membrane translocase subunit Tim13

1

1

High-throughput

0.437

High

110683

H3BSK8
RB binding protein 6, ubiquitin ligase

1

1

High-throughput

0.407

High

1057823

GSE1
Genetic suppressor element 1

2

0

High-throughput

0.328

High

1158559

ARK2N
Protein ARK2N

2

0

High-throughput

0.328

High

1158582

TOPRS
E3 ubiquitin-protein ligase Topors

2

0

High-throughput

0.328

High

62504

ZN316
Zinc finger protein 316

1

0

High-throughput

0.279

Low

1158542

NKAP1
Uncharacterized protein NKAPD1

1

0

High-throughput

0.279

Low

1158565

ZN668
Zinc finger protein 668

1

0

High-throughput

0.279

Low

1158576

LNP
Endoplasmic reticulum junction formation protein lunapark

1

0

High-throughput

0.279

Low

329785

AGR2
Anterior gradient protein 2 homolog

1

0

High-throughput

0.249

Low

110824

H7C0N4
Splicing factor 1

1

0

High-throughput

0.232

Low


Service provided by Combinatics, Japan

Last updated: 15 Jul 2024