Protein: CDC7
Cell division cycle 7-related protein kinase (CDC7-related kinase) (HsCdc7) (huCdc7) (EC 2.7.11.1)

Gene: CDC7
Organism: Homo sapiens
Interactions: 119
UniProt ID: O00311

Gene Ontology (top 5):
GO:0000082 - G1/S transition of mitotic cell cycle
GO:0000727 - double-strand break repair via break-induced replication
GO:0004672 - protein kinase activity
GO:0004674 - protein serine/threonine kinase activity
GO:0005524 - ATP binding

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

125930

DBF4A
Protein DBF4 homolog A

16

5

Small-scale

0.988

High

125908

DBF4B
Protein DBF4 homolog B

4

5

Small-scale

0.895

High

125846

CDK2
Cyclin-dependent kinase 2

2

19

Small-scale

0.812

High

125881

IKZF1
DNA-binding protein Ikaros

2

7

High-throughput

0.783

High

125905

ZBT8B
Zinc finger and BTB domain-containing protein 8B

2

8

High-throughput

0.783

High

125916

IKZF4
Zinc finger protein Eos

2

9

High-throughput

0.783

High

125923

ZBT26
Zinc finger and BTB domain-containing protein 26

2

3

High-throughput

0.783

High

125932

IKZF3
Zinc finger protein Aiolos

2

7

High-throughput

0.783

High

125859

MCM2
DNA replication licensing factor MCM2

11

20

Small-scale

0.755

High

125863

CDK9
Cyclin-dependent kinase 9

1

20

High-throughput

0.698

High

125839

CDK4
Cyclin-dependent kinase 4

1

19

High-throughput

0.692

High

125853

CDN1A
Cyclin-dependent kinase inhibitor 1

1

11

High-throughput

0.692

High

125843

CSK22
Casein kinase II subunit alpha'

1

20

High-throughput

0.691

High

125855

CETN2
Centrin-2

1

13

High-throughput

0.691

High

125861

CDK7
Cyclin-dependent kinase 7

1

19

High-throughput

0.691

High

125865

CCNH
Cyclin-H

1

20

High-throughput

0.691

High

125866

MAT1
CDK-activating kinase assembly factor MAT1

1

1

High-throughput

0.691

High

125868

RD23B
UV excision repair protein RAD23 homolog B

1

12

High-throughput

0.691

High

125888

MK06
Mitogen-activated protein kinase 6

1

20

High-throughput

0.691

High

125937

IF2B2
Insulin-like growth factor 2 mRNA-binding protein 2

1

12

High-throughput

0.691

High

125850

MCM4
DNA replication licensing factor MCM4

3

17

Small-scale

0.650

High

125852

MCM7
DNA replication licensing factor MCM7

3

19

Small-scale

0.650

High

125822

CDC7
Cell division cycle 7-related protein kinase

1

16

Small-scale

0.647

High

125920

CLSPN
Claspin

2

6

Small-scale

0.646

High

125847

MCM3
DNA replication licensing factor MCM3

2

20

Small-scale

0.619

High

62518

RFOX3
RNA binding protein fox-1 homolog 3

1

9

High-throughput

0.618

High

125826

RFOX2
RNA binding protein fox-1 homolog 2

1

8

High-throughput

0.618

High

125854

CCNF
Cyclin-F

1

20

High-throughput

0.618

High

125917

Q9H4D1
Protein kinase

1

16

High-throughput

0.618

High

125918

PKHA4
Pleckstrin homology domain-containing family A member 4

1

20

High-throughput

0.618

High

125927

RFOX1
RNA binding protein fox-1 homolog 1

1

10

High-throughput

0.618

High

125933

CILK1
Serine/threonine-protein kinase ICK

1

19

Small-scale

0.618

High

125830

STAM2
Signal transducing adapter molecule 2

2

6

High-throughput

0.606

High

125831

TRI37
E3 ubiquitin-protein ligase TRIM37

2

20

High-throughput

0.606

High

125840

TRI27
Zinc finger protein RFP

2

7

High-throughput

0.606

High

125864

FXR1
RNA-binding protein FXR1

2

6

High-throughput

0.606

High

125876

GOGA2
Golgin subfamily A member 2

2

20

High-throughput

0.606

High

125879

CACO2
Calcium-binding and coiled-coil domain-containing protein 2

2

20

High-throughput

0.606

High

125892

MTUS2
Microtubule-associated tumor suppressor candidate 2

2

20

High-throughput

0.606

High

125895

HMBX1
Homeobox-containing protein 1

2

6

High-throughput

0.606

High

125913

ZBT10
Zinc finger and BTB domain-containing protein 10

2

7

High-throughput

0.606

High

125931

GMEB2
Glucocorticoid modulatory element-binding protein 2

2

2

High-throughput

0.606

High

125934

LZTS1
Leucine zipper putative tumor suppressor 1

2

20

High-throughput

0.606

High

125886

MCM6
DNA replication licensing factor MCM6

2

20

Small-scale

0.602

High

125936

ORC6
Origin recognition complex subunit 6

2

0

Small-scale

0.588

High

125869

BI1
Bax inhibitor 1

2

0

High-throughput

0.580

High

125885

SRTD2
SERTA domain-containing protein 2

2

0

High-throughput

0.580

High

125891

TXIP1
Translin-associated factor X-interacting protein 1

2

0

High-throughput

0.580

High

125904

BANP
Protein BANP

2

0

High-throughput

0.580

High

125878

CAF1A
Chromatin assembly factor 1 subunit A

1

8

Small-scale

0.578

High

125871

RIPK4
Receptor-interacting serine/threonine-protein kinase 4

1

15

High-throughput

0.575

High

125833

PGK1
Phosphoglycerate kinase 1

1

1

Small-scale

0.561

High

125862

TOB1
Protein Tob1

1

1

Small-scale

0.561

High

125915

MCMBP
Mini-chromosome maintenance complex-binding protein

2

0

Small-scale

0.559

High

125928

GOG6A
Golgin subfamily A member 6A

2

20

High-throughput

0.553

High

125929

GRHPR
Glyoxylate reductase/hydroxypyruvate reductase

1

8

High-throughput

0.541

High

125926

RAD18
E3 ubiquitin-protein ligase RAD18

1

0

Small-scale

0.537

High

125828

ORC5
Origin recognition complex subunit 5

1

7

High-throughput

0.536

High

125856

CDN2A
Cyclin-dependent kinase inhibitor 2A

1

17

High-throughput

0.536

High

125898

MCM10
Protein MCM10 homolog

1

2

High-throughput

0.536

High

125841

ERCC2
General transcription and DNA repair factor IIH helicase subunit XPD

1

1

High-throughput

0.536

High

125842

ERCC3
General transcription and DNA repair factor IIH helicase/translocase subunit XPB

1

14

High-throughput

0.536

High

125848

ERCC5
DNA excision repair protein ERCC-5

1

5

High-throughput

0.536

High

125872

RACK1
Small ribosomal subunit protein RACK1

1

16

High-throughput

0.536

High

125877

TWF1
Twinfilin-1

1

5

High-throughput

0.536

High

125893

RM02
Large ribosomal subunit protein uL2m

1

2

High-throughput

0.536

High

125899

HDGR2
Hepatoma-derived growth factor-related protein 2

1

4

High-throughput

0.536

High

125921

IF122
Intraflagellar transport protein 122 homolog

1

11

High-throughput

0.536

High

125924

SEC12
Guanine nucleotide-exchange factor SEC12

1

16

High-throughput

0.536

High

125823

SOCS6
Suppressor of cytokine signaling 6

1

20

High-throughput

0.515

High

125902

SLX4
Structure-specific endonuclease subunit SLX4

1

13

High-throughput

0.515

High

125837

TSPYA
Testis-specific Y-encoded protein 10

1

12

High-throughput

0.515

High

125857

HD
Huntingtin

1

4

High-throughput

0.515

High

125894

Q6FHY5
MEOX2 protein

1

5

High-throughput

0.515

High

125836

ERCC1
DNA excision repair protein ERCC-1

1

0

High-throughput

0.513

High

125844

XPA
DNA repair protein complementing XP-A cells

1

0

High-throughput

0.513

High

125849

TF2H1
General transcription factor IIH subunit 1

1

0

High-throughput

0.513

High

125867

HMGA2
High mobility group protein HMGI-C

1

0

High-throughput

0.513

High

125874

XPC
DNA repair protein complementing XP-C cells

1

0

High-throughput

0.513

High

125884

TF2H3
General transcription factor IIH subunit 3

1

0

High-throughput

0.513

High

125897

TF2H5
General transcription factor IIH subunit 5

1

0

High-throughput

0.513

High

125911

TF2H4
General transcription factor IIH subunit 4

1

0

High-throughput

0.513

High

125912

XPF
DNA repair endonuclease XPF

1

0

High-throughput

0.513

High

125835

A4
Amyloid-beta precursor protein

1

12

High-throughput

0.501

High

125845

ALAT1
Alanine aminotransferase 1

1

3

High-throughput

0.494

High

125935

ICE1
Little elongation complex subunit 1

1

0

High-throughput

0.493

High

125858

CAPZB
F-actin-capping protein subunit beta

1

5

High-throughput

0.489

High

125870

ECHB
Trifunctional enzyme subunit beta, mitochondrial

1

2

High-throughput

0.489

High

125875

PLOD1
Procollagen-lysine,2-oxoglutarate 5-dioxygenase 1

1

1

High-throughput

0.489

High

125887

I13R2
Interleukin-13 receptor subunit alpha-2

1

4

High-throughput

0.489

High

125889

MIC60
MICOS complex subunit MIC60

1

1

High-throughput

0.489

High

125906

GT251
Procollagen galactosyltransferase 1

1

1

High-throughput

0.489

High

125914

HIPL1
HHIP-like protein 1

1

3

High-throughput

0.489

High

125851

MCM5
DNA replication licensing factor MCM5

1

20

Small-scale

0.481

High

125860

MEOX2
Homeobox protein MOX-2

1

5

High-throughput

0.481

High

125873

TSPY1
Testis-specific Y-encoded protein 1

1

11

High-throughput

0.481

High

125880

ORC1
Origin recognition complex subunit 1

1

7

Small-scale

0.481

High

125901

HOMEZ
Homeobox and leucine zipper protein Homez

1

2

High-throughput

0.481

High

125909

DTD1
D-aminoacyl-tRNA deacylase 1

1

0

Small-scale

0.480

High

125824

DVL2
Segment polarity protein dishevelled homolog DVL-2

1

20

High-throughput

0.479

High

125825

XPO1
Exportin-1

1

18

High-throughput

0.479

High

125827

PRC1
Protein regulator of cytokinesis 1

1

6

High-throughput

0.479

High

125829

PSIP1
PC4 and SFRS1-interacting protein

1

4

High-throughput

0.479

High

125834

P53
Cellular tumor antigen p53

1

12

High-throughput

0.479

High

125882

CUL3
Cullin-3

1

11

High-throughput

0.479

High

125883

TF2H2
General transcription factor IIH subunit 2

1

1

High-throughput

0.479

High

125900

SHLD2
Shieldin complex subunit 2

1

1

High-throughput

0.479

High

125903

KMT2E
Inactive histone-lysine N-methyltransferase 2E

1

9

Small-scale

0.479

High

125919

EGLN3
Prolyl hydroxylase EGLN3

1

4

High-throughput

0.479

High

125922

CENPJ
Centromere protein J

1

20

High-throughput

0.479

High

125938

Q9Y6T4
NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 2, mitochondrial

1

1

High-throughput

0.470

High

125832

NDUB2
NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 2, mitochondrial

1

1

High-throughput

0.439

High

125925

DISC1
Disrupted in schizophrenia 1 protein

1

2

High-throughput

0.417

High

125896

T2H2L
General transcription factor IIH subunit 2-like protein

1

1

High-throughput

0.407

High

125907

MOT11
Monocarboxylate transporter 11

1

1

High-throughput

0.407

High

125910

PO210
Nuclear pore membrane glycoprotein 210

1

0

High-throughput

0.279

Low

125890

CL16A
Protein CLEC16A

1

0

High-throughput

0.249

Low

125838

AMY1B
Alpha-amylase 1B

1

0

High-throughput

0.232

Low


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Last updated: 15 Jul 2024