Protein: HAVR2
Hepatitis A virus cellular receptor 2 (HAVcr-2) (T-cell immunoglobulin and mucin domain-containing protein 3) (TIMD-3) (T-cell immunoglobulin mucin receptor 3) (TIM-3) (T-cell membrane protein 3) (CD antigen CD366)

Gene: HAVR2, HAVCR2
Organism: Homo sapiens
Interactions: 94
UniProt ID: Q8TDQ0

Gene Ontology (top 5):
GO:0001772 - immunological synapse
GO:0002250 - adaptive immune response
GO:0002281 - macrophage activation involved in immune response
GO:0002519 - natural killer cell tolerance induction
GO:0002652 - regulation of tolerance induction dependent upon immune response

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

646054

AVR2A
Activin receptor type-2A

2

3

High-throughput

0.811

High

738384

BMR1A
Bone morphogenetic protein receptor type-1A

2

3

High-throughput

0.811

High

787275

PK3CA
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform

2

2

High-throughput

0.811

High

232943

PHLP1
PH domain leucine-rich repeat-containing protein phosphatase 1

2

0

High-throughput

0.770

High

128887

P3C2A
Phosphatidylinositol 4-phosphate 3-kinase C2 domain-containing subunit alpha

2

2

High-throughput

0.726

High

787383

PK3CB
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform

2

2

High-throughput

0.726

High

1082015

PKN2
Serine/threonine-protein kinase N2

2

1

High-throughput

0.726

High

1160261

PKN3
Serine/threonine-protein kinase N3

2

1

High-throughput

0.726

High

383892

ERBB2
Receptor tyrosine-protein kinase erbB-2

1

1

High-throughput

0.691

High

532371

CEAM1
Carcinoembryonic antigen-related cell adhesion molecule 1

1

1

Small-scale

0.690

High

301217

RHBT3
Rho-related BTB domain-containing protein 3

2

0

High-throughput

0.679

High

942472

CNTP1
Contactin-associated protein 1

2

0

High-throughput

0.679

High

1057182

MELK
Maternal embryonic leucine zipper kinase

2

0

High-throughput

0.679

High

1127493

WDR44
WD repeat-containing protein 44

2

0

High-throughput

0.679

High

1242525

CBPC5
Cytosolic carboxypeptidase-like protein 5

2

0

High-throughput

0.679

High

1255250

UTP4
U3 small nucleolar RNA-associated protein 4 homolog

2

0

High-throughput

0.679

High

1255251

S22AI
Solute carrier family 22 member 18

2

0

High-throughput

0.679

High

1255272

TTF2
Transcription termination factor 2

2

0

High-throughput

0.679

High

1255263

Q9H4D1
Protein kinase

2

2

High-throughput

0.675

High

655427

P85A
Phosphatidylinositol 3-kinase regulatory subunit alpha

3

2

Small-scale

0.667

High

1255252

ORAI1
Calcium release-activated calcium channel protein 1

1

0

High-throughput

0.656

High

1255259

LGR4
Leucine-rich repeat-containing G-protein coupled receptor 4

1

0

High-throughput

0.656

High

1255270

NOCT
Nocturnin

1

0

High-throughput

0.656

High

616843

JAK1
Tyrosine-protein kinase JAK1

2

5

High-throughput

0.628

High

669189

TYK2
Non-receptor tyrosine-protein kinase TYK2

2

4

High-throughput

0.628

High

1057902

DIP2A
Disco-interacting protein 2 homolog A

2

2

High-throughput

0.628

High

1255274

NISCH
Nischarin

2

1

High-throughput

0.628

High

119454

LEG9
Galectin-9

1

1

Small-scale

0.618

High

395295

A4
Amyloid-beta precursor protein

1

0

High-throughput

0.614

High

297384

MYO1D
Unconventional myosin-Id

2

0

High-throughput

0.602

High

473407

CISD3
CDGSH iron-sulfur domain-containing protein 3, mitochondrial

2

0

High-throughput

0.602

High

856892

DGKQ
Diacylglycerol kinase theta

2

0

High-throughput

0.602

High

1255254

MYADM
Myeloid-associated differentiation marker

2

0

High-throughput

0.602

High

1255260

ZDHC5
Palmitoyltransferase ZDHHC5

2

0

High-throughput

0.602

High

1255265

IL1AP
Interleukin-1 receptor accessory protein

2

0

High-throughput

0.602

High

1255267

CLDN1
Claudin domain-containing protein 1

2

0

High-throughput

0.602

High

411802

LCK
Tyrosine-protein kinase Lck

2

2

Small-scale

0.588

High

1137886

MRCKA
Serine/threonine-protein kinase MRCK alpha

1

0

High-throughput

0.578

High

1246449

WDR36
WD repeat-containing protein 36

1

0

High-throughput

0.578

High

1255275

UTP18
U3 small nucleolar RNA-associated protein 18 homolog

1

0

High-throughput

0.578

High

129319

P85B
Phosphatidylinositol 3-kinase regulatory subunit beta

2

6

High-throughput

0.574

High

309502

MTMR5
Myotubularin-related protein 5

2

1

High-throughput

0.574

High

1040873

MTMR1
Myotubularin-related protein 1

2

1

High-throughput

0.574

High

1145407

LPCT4
Lysophospholipid acyltransferase LPCAT4

2

1

High-throughput

0.574

High

1253562

P4K2B
Phosphatidylinositol 4-kinase type 2-beta

2

1

High-throughput

0.574

High

1255249

P55G
Phosphatidylinositol 3-kinase regulatory subunit gamma

2

6

High-throughput

0.574

High

1255256

PKP4
Plakophilin-4

2

1

High-throughput

0.574

High

1255257

PLCA
1-acyl-sn-glycerol-3-phosphate acyltransferase alpha

2

1

High-throughput

0.574

High

1255258

PKP2
Plakophilin-2

2

1

High-throughput

0.574

High

1255266

AT132
Polyamine-transporting ATPase 13A2

2

1

High-throughput

0.574

High

1255269

DIP2B
Disco-interacting protein 2 homolog B

2

2

High-throughput

0.574

High

803662

BAG6
Large proline-rich protein BAG6

1

3

Small-scale

0.553

High

1065077

SNX17
Sorting nexin-17

1

1

High-throughput

0.536

High

1061733

Q149M6
Exophilin 5

2

1

High-throughput

0.533

High

883575

RIPK4
Receptor-interacting serine/threonine-protein kinase 4

1

2

High-throughput

0.514

High

1255255

Q96T11
cDNA FLJ14518 fis, clone NT2RM1000850, weakly similar to ANKYRIN R

1

2

High-throughput

0.514

High

1114162

TBB8
Tubulin beta-8 chain

1

0

High-throughput

0.513

High

1243573

EXPH5
Exophilin-5

2

1

High-throughput

0.504

High

412276

FYN
Tyrosine-protein kinase Fyn

1

2

Small-scale

0.484

High

796479

ZAP70
Tyrosine-protein kinase ZAP-70

1

4

Small-scale

0.484

High

796614

KSYK
Tyrosine-protein kinase SYK

1

6

Small-scale

0.484

High

1255264

SH22A
SH2 domain-containing protein 2A

1

6

Small-scale

0.442

High

548736

VAV
Proto-oncogene vav

1

0

Small-scale

0.426

High

1255273

SH2B3
SH2B adapter protein 3

1

4

Small-scale

0.407

High

62578

TCAF2
TRPM8 channel-associated factor 2

2

0

High-throughput

0.328

High

159384

PLD2
Phospholipase D2

2

0

High-throughput

0.328

High

322018

ZMYM6
Zinc finger MYM-type protein 6

2

0

High-throughput

0.328

High

783919

TSN7
Tetraspanin-7

2

0

High-throughput

0.328

High

994713

S20A2
Sodium-dependent phosphate transporter 2

2

0

High-throughput

0.328

High

1120113

TIGD5
Tigger transposable element-derived protein 5

2

0

High-throughput

0.328

High

1136465

M3K21
Mitogen-activated protein kinase kinase kinase 21

2

0

High-throughput

0.328

High

1190972

GOGA7
Golgin subfamily A member 7

2

0

High-throughput

0.328

High

1192296

PKHH3
Pleckstrin homology domain-containing family H member 3

2

0

High-throughput

0.328

High

1218648

DEN6A
Protein DENND6A

2

0

High-throughput

0.328

High

1221521

PLPL6
Patatin-like phospholipase domain-containing protein 6

2

0

High-throughput

0.328

High

1239572

KDM1B
Lysine-specific histone demethylase 2

2

0

High-throughput

0.328

High

1253793

CERK1
Ceramide kinase

2

0

High-throughput

0.328

High

1231687

TM86A
Lysoplasmalogenase TMEM86A

2

0

High-throughput

0.316

High

1255253

SC22A
Vesicle-trafficking protein SEC22a

2

0

High-throughput

0.316

High

157617

MGST3
Glutathione S-transferase 3, mitochondrial

1

0

High-throughput

0.279

Low

316688

ACSL3
Fatty acid CoA ligase Acsl3

1

0

High-throughput

0.279

Low

741153

PIGA
Phosphatidylinositol N-acetylglucosaminyltransferase subunit A

1

0

High-throughput

0.279

Low

1150537

IQEC1
IQ motif and SEC7 domain-containing protein 1

1

0

High-throughput

0.279

Low

1160627

CNKR3
Connector enhancer of kinase suppressor of ras 3

1

0

High-throughput

0.279

Low

1244810

BBS1
Bardet-Biedl syndrome 1 protein

1

0

High-throughput

0.279

Low

1255261

CCDC8
Coiled-coil domain-containing protein 8

1

0

High-throughput

0.279

Low

1255262

PIGM
GPI mannosyltransferase 1

1

0

High-throughput

0.279

Low

1255268

GSKIP
GSK3B-interacting protein

1

0

High-throughput

0.279

Low

1255271

ERG28
Ergosterol biosynthetic protein 28 homolog

1

0

High-throughput

0.269

Low

581029

PLCG1
1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-1

1

0

Small-scale

0.253

Low

66881

D11L8
Putative ATP-dependent RNA helicase DDX11-like protein 8

1

0

High-throughput

0.232

Low

890761

PTEN
Phosphatidylinositol 3,4,5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase PTEN

1

0

Small-scale

0.232

Low

940671

3BP2
SH3 domain-binding protein 2

1

0

Small-scale

0.232

Low

1024143

LCP2
Lymphocyte cytosolic protein 2

1

0

Small-scale

0.232

Low


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Last updated: 15 Jul 2024