Protein: DCAF8
DDB1- and CUL4-associated factor 8 (WD repeat-containing protein 42A)

Gene: DCAF8
Organism: Homo sapiens
Interactions: 141
UniProt ID: Q5TAQ9

Gene Ontology (top 5):
GO:0005634 - nucleus
GO:0005654 - nucleoplasm
GO:0005737 - cytoplasm
GO:0005739 - mitochondrion
GO:0005829 - cytosol

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

1082225

DDB1
DNA damage-binding protein 1

15

20

Small-scale

0.984

High

62660

DC8L1
DDB1- and CUL4-associated factor 8-like protein 1

2

19

High-throughput

0.811

High

1135829

ARHGQ
Rho guanine nucleotide exchange factor 26

2

10

High-throughput

0.811

High

1135860

FARP1
FERM, ARHGEF and pleckstrin domain-containing protein 1

2

5

High-throughput

0.811

High

1135842

WDR76
WD repeat-containing protein 76

2

18

Small-scale

0.806

High

1043043

CUL4A
Cullin-4A

10

20

Small-scale

0.754

High

1043405

CUL4B
Cullin-4B

7

20

Small-scale

0.747

High

203704

SUV91
Histone-lysine N-methyltransferase SUV39H1

1

7

High-throughput

0.740

High

1135833

MDFI
MyoD family inhibitor

4

1

High-throughput

0.709

High

794393

GRK6
G protein-coupled receptor kinase 6

1

8

High-throughput

0.691

High

231552

KIF1B
Kinesin-like protein KIF1B

1

5

High-throughput

0.665

High

1135836

DDA1
DET1- and DDB1-associated protein 1

3

6

Small-scale

0.656

High

227711

PRKN
E3 ubiquitin-protein ligase parkin

3

16

High-throughput

0.650

High

573301

TCPA
T-complex protein 1 subunit alpha

2

20

High-throughput

0.628

High

826701

TCPG
T-complex protein 1 subunit gamma

2

20

High-throughput

0.628

High

843239

TCPD
T-complex protein 1 subunit delta

2

20

High-throughput

0.628

High

943278

TCPB
T-complex protein 1 subunit beta

2

20

High-throughput

0.628

High

964787

AMPD2
AMP deaminase 2

2

1

High-throughput

0.628

High

1135806

ACD11
Acyl-CoA dehydrogenase family member 11

2

2

High-throughput

0.628

High

1135819

TCPW
T-complex protein 1 subunit zeta-2

2

20

High-throughput

0.628

High

1135830

REXO5
RNA exonuclease 5

2

6

High-throughput

0.628

High

1135834

TCPH
T-complex protein 1 subunit eta

2

20

High-throughput

0.628

High

1135843

E41L5
Band 4.1-like protein 5

2

7

High-throughput

0.628

High

1067514

P2RY6
P2Y purinoceptor 6

1

1

High-throughput

0.618

High

182791

R113A
E3 ubiquitin-protein ligase RNF113A

1

2

High-throughput

0.618

High

896123

UBC12
NEDD8-conjugating enzyme Ubc12

1

7

High-throughput

0.618

High

908679

UBE2H
Ubiquitin-conjugating enzyme E2 H

1

11

High-throughput

0.618

High

1135805

TRI67
Tripartite motif-containing protein 67

1

19

High-throughput

0.618

High

1135838

AMRA1
Activating molecule in BECN1-regulated autophagy protein 1

1

15

High-throughput

0.618

High

1135854

FBW1B
F-box/WD repeat-containing protein 11

1

18

High-throughput

0.618

High

72381

B3KW44
tRNA N(3)-methylcytidine methyltransferase

2

1

High-throughput

0.611

High

1135824

CSN5
COP9 signalosome complex subunit 5

2

9

High-throughput

0.611

High

1108757

INAVA
Innate immunity activator protein

2

0

High-throughput

0.602

High

162844

XPO1
Exportin-1

2

20

Small-scale

0.601

High

103751

G5E9A7
DM1 locus, WD repeat containing

1

19

High-throughput

0.594

High

374369

RAF1
RAF proto-oncogene serine/threonine-protein kinase

2

7

Small-scale

0.586

High

1135823

GGH
Gamma-glutamyl hydrolase

2

0

High-throughput

0.585

High

1135852

ZRAN1
Ubiquitin thioesterase ZRANB1

2

7

High-throughput

0.584

High

1135846

HELLS
Lymphoid-specific helicase

1

20

Small-scale

0.578

High

1135802

TENS2
Tensin-2

2

6

High-throughput

0.576

High

1135821

P55G
Phosphatidylinositol 3-kinase regulatory subunit gamma

2

3

High-throughput

0.576

High

1135816

TFB1M
Dimethyladenosine transferase 1, mitochondrial

2

1

High-throughput

0.574

High

1135835

ANM1
Protein arginine N-methyltransferase 1

1

8

High-throughput

0.573

High

1135847

THAP1
THAP domain-containing protein 1

1

3

High-throughput

0.573

High

805438

MP2K3
Dual specificity mitogen-activated protein kinase kinase 3

2

9

High-throughput

0.571

High

1135808

CSN6
COP9 signalosome complex subunit 6

2

7

High-throughput

0.571

High

1135837

TRI54
Tripartite motif-containing protein 54

1

17

High-throughput

0.568

High

1135815

DPTOR
DEP domain-containing mTOR-interacting protein

1

3

Small-scale

0.553

High

1135825

RBPMS
RNA-binding protein with multiple splicing

1

0

High-throughput

0.549

High

882924

RBM11
Splicing regulator RBM11

1

10

High-throughput

0.541

High

1135827

GTPB3
tRNA modification GTPase GTPBP3, mitochondrial

1

7

High-throughput

0.541

High

547093

EZRI
Ezrin

1

7

High-throughput

0.536

High

770879

TCPZ
T-complex protein 1 subunit zeta

1

20

High-throughput

0.536

High

821253

TCPE
T-complex protein 1 subunit epsilon

1

20

High-throughput

0.536

High

851534

NEK4
Serine/threonine-protein kinase Nek4

1

10

High-throughput

0.536

High

890200

SC61B
Protein transport protein Sec61 subunit beta

1

2

High-throughput

0.536

High

919113

RAN
GTP-binding nuclear protein Ran

1

5

High-throughput

0.536

High

983622

FAK1
Focal adhesion kinase 1

1

8

High-throughput

0.536

High

1035113

MYO9B
Unconventional myosin-IXb

1

10

High-throughput

0.536

High

1047385

PDE7A
High affinity 3',5'-cyclic-AMP phosphodiesterase 7A

1

3

High-throughput

0.536

High

1115176

PAR14
Protein mono-ADP-ribosyltransferase PARP14

1

8

High-throughput

0.536

High

1135803

SFRP4
Secreted frizzled-related protein 4

1

1

High-throughput

0.536

High

1135810

PODN
Podocan

1

4

High-throughput

0.536

High

1135844

PAK6
Serine/threonine-protein kinase PAK 6

1

4

High-throughput

0.536

High

1135849

FAKD2
FAST kinase domain-containing protein 2, mitochondrial

1

2

High-throughput

0.536

High

853619

IMA5
Importin subunit alpha-5

1

4

Small-scale

0.534

High

1060777

IMB1
Importin subunit beta-1

1

8

Small-scale

0.515

High

218019

PEX1
Peroxisomal ATPase PEX1

1

6

High-throughput

0.515

High

388499

HSPB1
Heat shock protein beta-1

1

4

High-throughput

0.515

High

422197

NFL
Neurofilament light polypeptide

1

8

High-throughput

0.515

High

719518

MERL
Merlin

1

7

High-throughput

0.515

High

772005

VHL
von Hippel-Lindau disease tumor suppressor

1

2

High-throughput

0.515

High

959948

TF2B
Transcription initiation factor IIB

1

2

High-throughput

0.515

High

966154

NC2B
Protein Dr1

1

3

High-throughput

0.515

High

1025781

TADBP
TAR DNA-binding protein 43

1

13

High-throughput

0.515

High

1135811

SPRE1
Sprouty-related, EVH1 domain-containing protein 1

1

1

High-throughput

0.515

High

1135859

RNF11
RING finger protein 11

1

2

High-throughput

0.515

High

1135861

TF3C3
General transcription factor 3C polypeptide 3

1

14

High-throughput

0.515

High

1055938

ZN460
Zinc finger protein 460

1

0

High-throughput

0.513

High

1135807

NDUF7
Protein arginine methyltransferase NDUFAF7, mitochondrial

1

0

High-throughput

0.513

High

1135850

STOX2
Storkhead-box protein 2

1

0

High-throughput

0.513

High

1135858

GSTK1
Glutathione S-transferase kappa 1

1

0

High-throughput

0.513

High

835400

GSK3A
Glycogen synthase kinase-3 alpha

1

6

High-throughput

0.508

High

358784

CRYAA
Alpha-crystallin A chain

1

4

High-throughput

0.501

High

1135851

SPAST
Spastin

1

11

Small-scale

0.501

High

1135826

TRI63
E3 ubiquitin-protein ligase TRIM63

1

17

High-throughput

0.500

High

203957

HTRA2
Serine protease HTRA2, mitochondrial

1

0

High-throughput

0.493

High

1135809

LYZL2
Lysozyme-like protein 2

1

1

High-throughput

0.489

High

1135814

CBPA6
Carboxypeptidase A6

1

1

High-throughput

0.489

High

1135856

PA2GD
Group IID secretory phospholipase A2

1

1

High-throughput

0.489

High

157211

BACH1
Transcription regulator protein BACH1

1

11

Small-scale

0.479

High

319227

BRD1
Bromodomain-containing protein 1

1

10

High-throughput

0.479

High

323817

BAG2
BAG family molecular chaperone regulator 2

1

5

Small-scale

0.479

High

347010

MYC
Myc proto-oncogene protein

1

20

High-throughput

0.479

High

551738

DESP
Desmoplakin

1

20

High-throughput

0.479

High

559751

H12
Histone H1.2

1

13

High-throughput

0.479

High

569809

CEBPB
CCAAT/enhancer-binding protein beta

1

10

High-throughput

0.479

High

573740

PTN1
Tyrosine-protein phosphatase non-receptor type 1

1

3

High-throughput

0.479

High

598163

FLNA
Filamin-A

1

15

High-throughput

0.479

High

622481

CCND1
G1/S-specific cyclin-D1

1

6

Small-scale

0.479

High

779566

CCNF
Cyclin-F

1

7

High-throughput

0.479

High

882359

BCAR1
Breast cancer anti-estrogen resistance protein 1

1

12

High-throughput

0.479

High

897260

CSN2
COP9 signalosome complex subunit 2

1

12

High-throughput

0.479

High

921292

RBX1
E3 ubiquitin-protein ligase RBX1

1

7

Small-scale

0.479

High

931678

CSK2B
Casein kinase II subunit beta

1

3

High-throughput

0.479

High

1035466

SMAD4
Mothers against decapentaplegic homolog 4

1

4

High-throughput

0.479

High

1036647

SQSTM
Sequestosome-1

1

7

High-throughput

0.479

High

1078304

MLF2
Myeloid leukemia factor 2

1

1

Small-scale

0.479

High

1085583

HIF1A
Hypoxia-inducible factor 1-alpha

1

9

Small-scale

0.479

High

1087898

PTN21
Tyrosine-protein phosphatase non-receptor type 21

1

12

High-throughput

0.479

High

1101101

CL16A
Protein CLEC16A

1

1

High-throughput

0.479

High

1114287

TIM50
Mitochondrial import inner membrane translocase subunit TIM50

1

2

Small-scale

0.479

High

1135818

DNJC9
DnaJ homolog subfamily C member 9

1

20

High-throughput

0.479

High

1135820

BAP1
Ubiquitin carboxyl-terminal hydrolase BAP1

1

5

High-throughput

0.479

High

1135822

ESR2
Estrogen receptor beta

1

20

High-throughput

0.479

High

1135840

EGLN3
Prolyl hydroxylase EGLN3

1

3

High-throughput

0.479

High

1135857

CSN3
COP9 signalosome complex subunit 3

1

12

High-throughput

0.479

High

660549

GRN
Progranulin

1

1

High-throughput

0.470

High

1135812

Q86WV8
TSC complex subunit 1

1

1

High-throughput

0.470

High

1135817

JPH3
Junctophilin-3

1

1

High-throughput

0.470

High

1135845

ANM8
Protein arginine N-methyltransferase 8

1

8

High-throughput

0.464

High

517297

PCNA
Proliferating cell nuclear antigen

1

0

Small-scale

0.458

High

673411

MPIP1
M-phase inducer phosphatase 1

1

0

Small-scale

0.458

High

1135828

GCP3
Gamma-tubulin complex component 3

1

0

High-throughput

0.458

High

1135832

PEO1
Twinkle mtDNA helicase

1

0

High-throughput

0.458

High

1135863

DNM3A
DNA

1

0

Small-scale

0.458

High

1135841

METL8
tRNA N(3)-methylcytidine methyltransferase METTL8, mitochondrial

1

1

High-throughput

0.445

High

100849

APRIO
Alternative prion protein

1

3

High-throughput

0.437

High

946540

DCD
Dermcidin

1

2

High-throughput

0.437

High

1135813

S15A3
Solute carrier family 15 member 3

1

1

High-throughput

0.437

High

1135831

DNJC1
DnaJ homolog subfamily C member 1

1

14

High-throughput

0.437

High

1135848

DJC28
DnaJ homolog subfamily C member 28

1

1

High-throughput

0.437

High

1135853

ZNHI2
Zinc finger HIT domain-containing protein 2

1

1

High-throughput

0.437

High

1135855

PNMA2
Paraneoplastic antigen Ma2

1

1

Small-scale

0.437

High

99624

F5H1C8
Solute carrier family 15 member 3

1

1

High-throughput

0.407

High

1135804

TMCO3
Transmembrane and coiled-coil domain-containing protein 3

2

0

High-throughput

0.328

High

812792

CASA1
Alpha-S1-casein [Cleaved into: Casoxin-D]

1

0

High-throughput

0.279

Low

1135801

LIPK
Lipase member K

1

0

High-throughput

0.279

Low

1135839

UN93B
Protein unc-93 homolog B1

1

0

High-throughput

0.279

Low

281669

WFS1
Wolframin

1

0

High-throughput

0.268

Low

1135862

DJC15
DnaJ homolog subfamily C member 15

1

0

High-throughput

0.249

Low


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Last updated: 15 Jul 2024